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Displaying drugs 2401 - 2425 of 6853 in total
Quercetin
Quercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Experimental
Investigational
Matched Synonyms: … 3,3',4',5,7-pentahydroxyflavone ... 3,5,7,3',4'-Pentahydroxyflavone ... FLAVONE, 3,3',4',5,7-PENTAHYDROXY- …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one …
Midecamycin
Midecamycin is a naturally occurring 16-membered macrolide that fits under the category of acetoxy-substituted macrolide antibiotics. In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar. Until 2017, midecamycin was still under the list of approved...
Experimental
Matched Iupac: … (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-4-(dimethylamino)-5-hydroxy-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-10 ... -hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-4-(propanoyloxy)-1-oxacyclohexadeca-11,13-dien- ... 6-yl]oxy}-2-methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl propanoate …
Matched Description: … 4 of the terminal sugar. ... In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position …
Matched Description: … 4 of the terminal sugar. ... In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position …
(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE
Experimental
Matched Name: … (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL …
Matched Iupac: … (1S,2R,5S)-5-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-2-(2,4,5-trifluorophenyl …
Matched Iupac: … (1S,2R,5S)-5-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-2-(2,4,5-trifluorophenyl …
BTA9881
BTA9881 is a respiratory syncytial virus (RSV) antiviral drug developed by the Australian company Biota Holdings. It is currently in phase I trials.
Investigational
99mTc-HYNIC (Tyr3)-octreotide
Investigational
Matched Iupac: … (99Tc)technetium(5+) 2-({2-[(carboxylatomethyl)amino]ethyl}amino)acetate 4-{[(4R,7S,10S,13R,16S,19R)- ... 10-(4-aminobutyl)-4-{[(2R,3R)-1,3-dihydroxybutan-2-yl]carbamoyl}-19-[(2R)-2-[(6-hydrazinylpyridin-3-yl …
KOS-1584
KOS-1584 is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. KOS-1584 is a second-generation compound with increased potency, favorable tissue distribution, and ease of formulation.
Investigational
Matched Iupac: … (4S,7R,8S,9S,10E,13Z,16S)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1E)-1-(2-methyl-1,3-thiazol-4-yl) …
Azosemide
Azosemide is a loop diuretic used to treat hypertension, edema, and ascites.
Investigational
Matched Synonyms: … 5-(4'-chloro-5'-sulfamoyl-2'-thenylaminophenyl)tetrazole ... 2-chloro-5-(1H-tetrazol-5-yl)-N4-2-thenylsulfanilamide …
Matched Iupac: … 2-chloro-5-(2H-1,2,3,4-tetrazol-5-yl)-4-{[(thiophen-2-yl)methyl]amino}benzene-1-sulfonamide …
Matched Iupac: … 2-chloro-5-(2H-1,2,3,4-tetrazol-5-yl)-4-{[(thiophen-2-yl)methyl]amino}benzene-1-sulfonamide …
ORC-13661
ORC-13661 is under investigation in clinical trial NCT05730283 (Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin).
Investigational
Matched Synonyms: … (1R,8S)-4-{[(4-chlorophenyl)carbamoyl]amino}-11-methyl-5-thia-11-azatricyclo[6.2.1.02,6]undeca ... (4R,6S)-2-[[[(4-Chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro-5-methyl-4,6-ethanothieno[3,2-c ... -5-methyl-, (4R,6S)- …
Technetium Tc-99m etifenin
Experimental
Fosbretabulin
Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Investigational
Matched Synonyms: … Combretastatin A-4 phosphate ... 2-METHOXY-5-((Z)-2-(3,4,5-TRIMETHOXYPHENYL)VINYL)PHENYL DIHYDROGEN PHOSPHATE ... PHENOL, 2-METHOXY-5-((Z)-2-(3,4,5-TRIMETHOXYPHENYL)ETHENYL)-, DIHYDROGEN PHOSPHATE …
Matched Iupac: … {2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy}phosphonic acid …
Matched Salts cas: … 404886-32-4 …
Matched Iupac: … {2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy}phosphonic acid …
Matched Salts cas: … 404886-32-4 …
KH064
Experimental
Matched Synonyms: … (S)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid ... 5-(4-Benzyloxyphenyl)-4S-(7-phenylheptanoylamino)pentanoic acid …
Matched Iupac: … (4S)-5-[4-(benzyloxy)phenyl]-4-(7-phenylheptanamido)pentanoic acid …
Matched Iupac: … (4S)-5-[4-(benzyloxy)phenyl]-4-(7-phenylheptanamido)pentanoic acid …
Orismilast
Orismilast is under investigation in clinical trial NCT05190419 (Study to Assess the Efficacy and Safety of Orismilast in Psoriasis).
Investigational
Matched Synonyms: … 2-(3,5-dichloro-1-oxido-4-pyridinyl)-1-(7-(difluoromethoxy)-2',3',5',6'-tetrahydro-1',1'-dioxidospiro ... (1,3-benzodioxole-2,4'-(4h)thiopyran)-4-yl)ethanone …
Stem-cell derived exosome vesicle products
Mesenchymal stem cells (MSCs) exert their therapeutic effects through multiple modalities, including paracrine factors such as exosomes. Exosomes are nanometer-sized, membrane-bound vesicles secreted for the purpose of cell-cell communication. Once secreted into extracellular fluid, exosomes are taken up by their target cells or carried to distant target sites. Various bioactive...
Investigational
Matched Description: … These exosomes can also consist of VEGF and matrix metalloproteinase-9 (MMP-9) which aid in angiogenesis …
3,5-dibromobiphenyl-4-ol
Experimental
Matched Name: … 3,5-dibromobiphenyl-4-ol …
Matched Iupac: … 3,5-dibromo-[1,1'-biphenyl]-4-ol …
Matched Iupac: … 3,5-dibromo-[1,1'-biphenyl]-4-ol …
4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine
Experimental
Matched Name: … 4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine …
Matched Iupac: … 4-methyl-5H,7H,8H-thiopyrano[4,3-d]pyrimidin-2-amine …
Matched Iupac: … 4-methyl-5H,7H,8H-thiopyrano[4,3-d]pyrimidin-2-amine …
SLC-391
Investigational
Matched Synonyms: … 2-Pyridinamine, 3-[5-(cyclopropylmethyl)-1,3,4-oxadiazol-2-yl]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- …
Giloralimab
Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination With IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis).
Investigational
Chrysoeriol
Investigational
Matched Synonyms: … 4h-1-benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)- ... 3'-methoxy-4',5,7-trihydroxyflavone …
Matched Iupac: … 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one …
Matched Iupac: … 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one …
Metavert
Investigational
Matched Synonyms: … Benzamide, n-hydroxy-4-(5-((4-methoxyphenyl)amino)-1,3,4-oxadiazol-2-yl)- ... N-hydroxy-4-(5-((4-methoxyphenyl)amino)-1,3,4-oxadiazol-2-yl)benzamide …
Matched Iupac: … N-hydroxy-4-{5-[(4-methoxyphenyl)amino]-1,3,4-oxadiazol-2-yl}benzamide …
Matched Iupac: … N-hydroxy-4-{5-[(4-methoxyphenyl)amino]-1,3,4-oxadiazol-2-yl}benzamide …
(5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-[[(S)-(4-fluorophenyl)-(2H-tetrazol-5-yl)methyl]amino]-1,3-thiazol-4-one
Experimental
Matched Name: … (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-[[(S)-(4-fluorophenyl)-(2H-tetrazol-5-yl)methyl]amino]-1,3- ... thiazol-4-one …
Matched Iupac: … }-4,5-dihydro-1,3-thiazol-4-one ... (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-{[(S)-(4-fluorophenyl)(1H-1,2,3,4-tetrazol-5-yl)methyl]amino …
Matched Iupac: … }-4,5-dihydro-1,3-thiazol-4-one ... (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-{[(S)-(4-fluorophenyl)(1H-1,2,3,4-tetrazol-5-yl)methyl]amino …
Trazpiroben
Investigational
Matched Synonyms: … (3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8 triazaspiro(4.5) decan-3-yl)methyl)benzoic acid ... Benzoic acid, 3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro(4.5)dec-3-yl)methyl)- …
Lorundrostat
Lorundrostat is under investigation in clinical trial NCT06153693 (Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension).
Investigational
Matched Synonyms: … 1-Piperazineacetamide, N-[trans-4-(acetylamino)cyclohexyl]-4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]- ... N-(trans-4-acetamidocyclohexyl)-2-{4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]piperazin-1-yl}acetamide …
Ralmitaront
Ralmitaront is under investigation in clinical trial NCT04512066 (A Trial of the Efficacy and the Safety of RO6889450 (Ralmitaront) vs Placebo in Patients With an Acute Exacerbation of Schizophrenia or Schizoaffective Disorder).
Investigational
Matched Synonyms: … 1h-pyrazole-3-carboxamide, 5-ethyl-4-methyl-n-(4-(2s)-2-morpholinylphenyl)- ... 5-ethyl-4-methyl-n-(4-((2s)-morpholin-2-yl)phenyl)-1h-pyrazole-3-carboxamide …
Carbopol 974P
Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. It was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies. The compound,...
Investigational
Displaying drugs 2401 - 2425 of 6853 in total