Displaying drugs 1 - 25 of 1932 in total
Hyaluronidase (human recombinant)
A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Synonyms: … Hyaluronidase human recombinant ... Hyaluronidase (human recombinant) ... Hyaluronidase recombinant human …
Matched Name: … Hyaluronidase (human recombinant) …
Matched Description: … A purified preparation of the enzyme recombinant human hyaluronidase. ... Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … Hyaluronidase ... HYLENEX Recombinant ... HYLENEX Recombinant Professional Sample …
Matched Name: … Hyaluronidase (human recombinant) …
Matched Description: … A purified preparation of the enzyme recombinant human hyaluronidase. ... Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … Hyaluronidase ... HYLENEX Recombinant ... HYLENEX Recombinant Professional Sample …
Insulin human
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Synonyms: … Insulin recombinant human ... Insulin recombinant purified human ... Human insulin …
Matched Name: … Insulin human …
Matched Description: … Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin ... Human Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the ... human insulin gene into Escherichia coli bacteria or Saccharomyces cerevisiae. …
Matched Mixtures name: … Humulin 30/70 (insulin Human Biosynth Inj) ... Humulin 30/70 (insulin Human Biosynth Inj) …
Matched Salts name: … Insulin human zinc suspension …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin (human) ... insulin (human) ... insulin (human) …
Matched Products: … Insulin Human Winthrop Rapid ... Insulin Human Winthrop Basal ... Insulin Human Winthrop Comb 15 …
Matched Name: … Insulin human …
Matched Description: … Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin ... Human Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the ... human insulin gene into Escherichia coli bacteria or Saccharomyces cerevisiae. …
Matched Mixtures name: … Humulin 30/70 (insulin Human Biosynth Inj) ... Humulin 30/70 (insulin Human Biosynth Inj) …
Matched Salts name: … Insulin human zinc suspension …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin (human) ... insulin (human) ... insulin (human) …
Matched Products: … Insulin Human Winthrop Rapid ... Insulin Human Winthrop Basal ... Insulin Human Winthrop Comb 15 …
Secretin human
Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Synonyms: … Human secretin ... Secretin human ... Secretin (human) …
Matched Name: … Secretin human …
Matched Description: … Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring ... , and liver. ... Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas …
Matched Salts name: … Secretin human pentahydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Secretin human …
Matched Description: … Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring ... , and liver. ... Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas …
Matched Salts name: … Secretin human pentahydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Tetanus immune globulin, human
Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients.
Approved
Matched Synonyms: … Tetanus immunoglobulin (human) ... Tetanus immunoglobulin ... Tetanus immune globulin human …
Matched Name: … Tetanus immune globulin, human …
Matched Description: … Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. ... It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in …
Matched Categories: … tetanus immunoglobulin ... Human Tetanus Immune Globulins ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … IGANTET ANTI-TETANUS IMMUNOGLOBULIN GRIFOLS INJECTION 250 IU/ml …
Matched Name: … Tetanus immune globulin, human …
Matched Description: … Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. ... It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in …
Matched Categories: … tetanus immunoglobulin ... Human Tetanus Immune Globulins ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … IGANTET ANTI-TETANUS IMMUNOGLOBULIN GRIFOLS INJECTION 250 IU/ml …
Human cytomegalovirus immune globulin
Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label].
Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to infections which are followed by life-long...
Approved
Matched Synonyms: … Human cytomegalovirus immunoglobulin ... Cytomegalovirus immunoglobulin ... Cytomegalovirus immune globulin (human) …
Matched Name: … Human cytomegalovirus immune globulin …
Matched Description: … It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. ... Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of ... Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to …
Matched Categories: … Human Immunoglobulin G ... Immunoglobulin G ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Immunoglobulin Isotypes …
Matched Name: … Human cytomegalovirus immune globulin …
Matched Description: … It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. ... Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of ... Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to …
Matched Categories: … Human Immunoglobulin G ... Immunoglobulin G ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Immunoglobulin Isotypes …
Antihemophilic factor human
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … F8 protein, human ... factor VIII, human ... Factor VIII (human) …
Matched Name: … Antihemophilic factor human …
Matched Description: … with conventional factor VIII due to conjugation to the dimeric Fc domain of human immunoglobulin G1 ... a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential ... ], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU …
Matched Name: … Antihemophilic factor human …
Matched Description: … with conventional factor VIII due to conjugation to the dimeric Fc domain of human immunoglobulin G1 ... a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential ... ], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU …
Anthrax immune globulin human
Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. It is derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified. Available as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing...
Approved
Matched Synonyms: … Anthrax immunoglobulin (human) ... Anthrax immune globulin human ... Anthrax immune globulin (human) …
Matched Name: … Anthrax immune globulin human …
Matched Description: … Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. ... It is administered in combination with appropriate antibiotic therapy as the immunoglobulin itself is ... polyclonal antibodies that bind the protective antigen (PA) component of Bacillus anthracis lethal and …
Matched Categories: … Human Immunoglobulin ... Amino Acids, Peptides, and Proteins …
Matched Name: … Anthrax immune globulin human …
Matched Description: … Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. ... It is administered in combination with appropriate antibiotic therapy as the immunoglobulin itself is ... polyclonal antibodies that bind the protective antigen (PA) component of Bacillus anthracis lethal and …
Matched Categories: … Human Immunoglobulin ... Amino Acids, Peptides, and Proteins …
Human albumin microspheres
Approved
Experimental
Matched Synonyms: … Albumin human, microspheres ... Albumin microsphere human serum ... Albumin, microsphere human serum …
Matched Name: … Human albumin microspheres …
Matched Name: … Human albumin microspheres …
Coagulation factor VII human
Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Approved
Investigational
Matched Synonyms: … Factor VII human ... Coagulation factor VII (human) ... Human coagulation factor VII …
Matched Name: … Coagulation factor VII human …
Matched Description: … Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... coagulation factor IX, II, VII and X in combination …
Matched Name: … Coagulation factor VII human …
Matched Description: … Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... coagulation factor IX, II, VII and X in combination …
Human papillomavirus type 31 L1 capsid protein antigen
Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 31. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 31 L1 protein ... L1 protein, Human papillomavirus type 31 Vaccine …
Matched Name: … Human papillomavirus type 31 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) type 31. ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 31 which are produced by separate fermentations in recombinant …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Name: … Human papillomavirus type 31 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) type 31. ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 31 which are produced by separate fermentations in recombinant …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 45 L1 capsid protein antigen
Human papillomavirus type 45 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 45. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 45 L1 protein ... L1 protein, Human papillomavirus type 45 Vaccine …
Matched Name: … Human papillomavirus type 45 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) type 45. ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 45 which are produced by separate fermentations in recombinant …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Name: … Human papillomavirus type 45 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) type 45. ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 45 which are produced by separate fermentations in recombinant …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 52 L1 capsid protein antigen
Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 52 The vaccine is prepared from the purified virus-like...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 52 L1 protein ... L1 protein, Human papillomavirus type 52 Vaccine …
Matched Name: … Human papillomavirus type 52 L1 capsid protein antigen …
Matched Description: … *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 52 which are produced by separate fermentations in recombinant ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Name: … Human papillomavirus type 52 L1 capsid protein antigen …
Matched Description: … *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 52 which are produced by separate fermentations in recombinant ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 18 L1 capsid protein antigen
Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Synonyms: … Recombinant human papillomavirus type 18 L1 protein ... L1 protein, Human papillomavirus type 18 Vaccine …
Matched Name: … Human papillomavirus type 18 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Matched Name: … Human papillomavirus type 18 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Antihemophilic factor (recombinant), PEGylated
Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label].
Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Synonyms: … Antihemophilic Factor (Recombinant), PEGylated ... antihemophilic factor (recombinant), PEGylated-aucl …
Matched Name: … Antihemophilic factor (recombinant), PEGylated …
Matched Description: … Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases …
Matched Categories: … Recombinant Proteins ... Human Antihemophilic Factors ... Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Matched Name: … Antihemophilic factor (recombinant), PEGylated …
Matched Description: … Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases …
Matched Categories: … Recombinant Proteins ... Human Antihemophilic Factors ... Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Hepatitis B immune globulin
Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Synonyms: … Human hepatitis B immunoglobulin ... Human hepatitis-B immunoglobulin ... Hepatitis B immunoglobulin (human) …
Matched Description: … The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. ... During the process, viruses are deactivated, and in the final steps, solvents used in the preparation ... According to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first …
Matched Categories: … Human Immunoglobulin ... hepatitis B immunoglobulin ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … HEPATITIS B IMMUNOGLOBULIN P BEHRING ... HEPATITIS B IMMUNOGLOBULIN P BEHRING 1000 IU/5 ML IM KULLANIMA HAZIR ENJEKTÖRDE ENJEKSİYONLUK ÇÖZELTİ ... HEPATITIS B IMMUNOGLOBULIN P BEHRING 200 IU/1 ML IM KULLANIMA HAZIR ENJEKTÖRDE ENJEKSİYONLUK ÇÖZELTİ …
Matched Description: … The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. ... During the process, viruses are deactivated, and in the final steps, solvents used in the preparation ... According to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first …
Matched Categories: … Human Immunoglobulin ... hepatitis B immunoglobulin ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … HEPATITIS B IMMUNOGLOBULIN P BEHRING ... HEPATITIS B IMMUNOGLOBULIN P BEHRING 1000 IU/5 ML IM KULLANIMA HAZIR ENJEKTÖRDE ENJEKSİYONLUK ÇÖZELTİ ... HEPATITIS B IMMUNOGLOBULIN P BEHRING 200 IU/1 ML IM KULLANIMA HAZIR ENJEKTÖRDE ENJEKSİYONLUK ÇÖZELTİ …
Reteplase
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) ... Reteplase,recombinant ... Reteplase, recombinant …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... human tPA. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... human tPA. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Human Thrombin (recombinant, glycosylated) ... Thrombin (synthetic human) …
Matched Description: … Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically ... The thrombin alfa product ultimate comes from recombinant human prethrombin-1 [L2079]. ... Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically ... The thrombin alfa product ultimate comes from recombinant human prethrombin-1 [L2079]. ... Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Natalizumab
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …
Matched Description: … Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Elosulfase alfa
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Recombinant human N-acetylgalactosamine-6-sulfatase ... Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS) …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim …
Matched Categories: … Recombinant Proteins ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Chondroitinases and Chondroitin Lyases …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim …
Matched Categories: … Recombinant Proteins ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Chondroitinases and Chondroitin Lyases …
Mecasermin
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I ... Mecasermin recombinant ... Human somatomedin C …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1 ... Human Insulin-like Growth Factor Analogs ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1 ... Human Insulin-like Growth Factor Analogs ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... sequence as human beta-glucuronidase (GUS) [FDA Label]. ... is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... sequence as human beta-glucuronidase (GUS) [FDA Label]. ... is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Interferon beta-1a
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta, recombinant human ... Interferon beta-1a (recombinant human) ... Interferon beta-1a,recombinant …
Matched Description: … Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. ... It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta …
Matched Categories: … Recombinant Human Interferon beta ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. ... It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta …
Matched Categories: … Recombinant Human Interferon beta ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Eftrenonacog alfa
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein ... Coagulation factor IX recombinant immunoglubulin g1 fusion protein …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. ... It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region …
Matched Categories: … Recombinant Proteins ... Enzymes and Coenzymes ... Immunoglobulin Fragments ... Amino Acids, Peptides, and Proteins ... Immunoglobulin Constant Regions …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. ... It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region …
Matched Categories: … Recombinant Proteins ... Enzymes and Coenzymes ... Immunoglobulin Fragments ... Amino Acids, Peptides, and Proteins ... Immunoglobulin Constant Regions …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER …
Matched Description: … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin ... [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. …
Matched Categories: … Immunoglobulin G ... Amino Acids, Peptides, and Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
Matched Description: … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin ... [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. …
Matched Categories: … Immunoglobulin G ... Amino Acids, Peptides, and Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
Insulin detemir
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human ... Insulin detemir recombinant …
Matched Description: … typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells ... tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells ... tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
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