Displaying drugs 1 - 25 of 15965 in total
Poliovirus type 1 antigen (formaldehyde inactivated)
Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 1. The vaccine contains purified and inactivated poliovirus type 1 that were...
Approved
Investigational
Matched Synonyms: … poliovirus vaccine inactivated, type 1 (Mahoney) ... Inactivated poliomyelitis vaccine (V.C.O.) type 1 Mahoney …
Matched Name: … Poliovirus type 1 antigen (formaldehyde inactivated) …
Matched Description: … The vaccine contains purified and inactivated poliovirus type 1 that were grown from a continuous line ... by poliovirus Type 1. ... of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused …
Matched Mixtures name: … HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... TETRAXIM 0.5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Name: … Poliovirus type 1 antigen (formaldehyde inactivated) …
Matched Description: … The vaccine contains purified and inactivated poliovirus type 1 that were grown from a continuous line ... by poliovirus Type 1. ... of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused …
Matched Mixtures name: … HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... TETRAXIM 0.5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Tovorafenib
Tovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements. BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation,...
Approved
Investigational
Matched Synonyms: … 6-Amino-5-chloro-N-((1R)-1-(5-(((5-chloro-4-(trifluoromethyl)-2-pyridinyl)amino)carbonyl)-2-thiazolyl ... 6-amino-5-chloro-N-[1R)-1-[5-[[[5-hloro-4-(trifluoromethyl)-2pyridinyl]amino]carbonyl]-2-thiazoyl]ethyl ... ]carbonyl]-2-thiazolyl]ethyl]- …
Matched Iupac: … 6-amino-5-chloro-N-[(1R)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl) …
Matched Description: … growth and survival. ... [A263602] Tovorafenib inhibits BRAF and blocks dysregulated signalling pathways related to cancer cell ... [L50587] BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation, and differentiation …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 6-amino-5-chloro-N-[(1R)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl) …
Matched Description: … growth and survival. ... [A263602] Tovorafenib inhibits BRAF and blocks dysregulated signalling pathways related to cancer cell ... [L50587] BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation, and differentiation …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 1 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Synonyms: … Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 1 …
Matched Name: … Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 1 …
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide ... 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Chlorpropamide
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Synonyms: … 4-chloro-N-((propylamino)carbonyl)benzenesulfonamide ... 4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide ... 1-(p-chlorobenzenesulfonyl)-3-propylurea …
Matched Iupac: … 1-(4-chlorobenzenesulfonyl)-3-propylurea …
Matched Description: … increase the number and sensitivity of insulin receptors. ... Renal and hepatic dysfunction may increase the risk of hypoglycemia. ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 1-(4-chlorobenzenesulfonyl)-3-propylurea …
Matched Description: … increase the number and sensitivity of insulin receptors. ... Renal and hepatic dysfunction may increase the risk of hypoglycemia. ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Daprodustat
Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Synonyms: … Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)- …
Matched Description: … [L43857] On February 1, 2023, daprodustat was fully approved by the FDA as the first oral treatment for ... HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Description: … [L43857] On February 1, 2023, daprodustat was fully approved by the FDA as the first oral treatment for ... HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Cyclacillin
A cyclohexylamido analog of penicillanic acid.
Approved
Matched Synonyms: … (2S,5R,6R)-6-{[(1-aminocyclohexyl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane ... (1-aminocyclohexyl)penicillin ... 6-(1-aminocyclohexylcarboxamido)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-6-(1-aminocyclohexaneamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Iupac: … (2S,5R,6R)-6-(1-aminocyclohexaneamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Cyd dengue virus serotype 1 live (attenuated) antigen
Approved
Matched Name: … Cyd dengue virus serotype 1 live (attenuated) antigen …
Matched Mixtures name: … DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION ... DENGVAXIA, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION …
Matched Mixtures name: … DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION ... DENGVAXIA, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION …
Apadamtase alfa
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible for cleaving ... rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... apadamtase alfa and cinaxadamtase alfa …
Matched Description: … metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible for cleaving ... rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... apadamtase alfa and cinaxadamtase alfa …
Penicillium glaucum
Penicillium glaucum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, penicillium glaucum ... Molds, rusts and smuts, penicillium glaucus …
Rezafungin
Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Synonyms: … Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2- …
Matched Iupac: … heptahydroxy-18-[(Z)-[hydroxy({4-[4'-(pentyloxy)-[1,1'-biphenyl]-4-yl]phenyl})methylidene]amino]-3,15-bis[(1R)-1- …
Matched Description: … _Candida tropicalis_, as well as other _Candida_ and _Aspergillus_ spp. ... Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily ... pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … heptahydroxy-18-[(Z)-[hydroxy({4-[4'-(pentyloxy)-[1,1'-biphenyl]-4-yl]phenyl})methylidene]amino]-3,15-bis[(1R)-1- …
Matched Description: … _Candida tropicalis_, as well as other _Candida_ and _Aspergillus_ spp. ... Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily ... pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Heterocyclic Compounds, 1-Ring …
Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol)
Approved
Matched Name: … Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) …
Matched Iupac: … sodium (2R)-1-[(2,3-dihydroxypropyl phosphono)oxy]-3-(hexadecanoyloxy)propan-2-yl hexadecanoate …
Matched Iupac: … sodium (2R)-1-[(2,3-dihydroxypropyl phosphono)oxy]-3-(hexadecanoyloxy)propan-2-yl hexadecanoate …
CVac
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …
Matched Products: … ACT-HIB 0,5ML IM/SC 1 FLK LIYOFILIZE ASI+1 ENJ. COZUCU …
Matched Description: … These are heat inactivated and purified. …
Matched Products: … ACT-HIB 0,5ML IM/SC 1 FLK LIYOFILIZE ASI+1 ENJ. COZUCU …
Flucloxacillin
Antibiotic analog of cloxacillin.
Approved
Investigational
Matched Synonyms: … -4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Products: … FLIX 1 GR 1 AMPUL ... Floxapen 1 g Trockenstechampullen ... Flucloxacillin WABO 1 g Pulver zur Herstellung einer Injektions-/Infusionslösung …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Products: … FLIX 1 GR 1 AMPUL ... Floxapen 1 g Trockenstechampullen ... Flucloxacillin WABO 1 g Pulver zur Herstellung einer Injektions-/Infusionslösung …
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … ),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, EC=3.5.4.4)-(1- ... PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... (CYS74>SER,ALA245>THR)ADENOSINE DEAMINASE (BOS TAURUS, BOVINE)-(1-356)-PEPTIDE, PRODUCED IN ESCHERICHIA …
Matched Description: … with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Influenza B virus B/Wisconsin/1/2010) antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Wisconsin/1/2010) antigen (MDCK cell derived, propiolactone inactivated) …
Matched Description: … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated …
Matched Description: … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated …
Gibberella fujikuroi
Gibberella fujikuroi allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, fusarium moniliforme …
Balsalazide
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt.
Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid ... 3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. …
Matched Categories: … Alimentary Tract and Metabolism …
Rilonacept
Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Synonyms: … interleukin-1 (IL-1) trap ... IL-1 TRAP ... IL-1-TRAP …
Matched Description: … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... Muckle-Wells Syndrome (MWS), in adults and children greater than 12 years old. ... Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interleukin-1 Blockers ... Receptors, Interleukin-1 Type I ... Interleukin-1 Receptor Accessory Protein …
Matched Description: … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... Muckle-Wells Syndrome (MWS), in adults and children greater than 12 years old. ... Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interleukin-1 Blockers ... Receptors, Interleukin-1 Type I ... Interleukin-1 Receptor Accessory Protein …
Bifonazole
Bifonazole is an azole antifungal drug.
Approved
Investigational
Matched Synonyms: … (+-)-1-(p,alpha-Diphenylbenzyl)imidazole ... 1-(p,alpha-Diphenylbenzyl)imidazole ... 1-(alpha-(4-Biphenylyl)benzyl)imidazole …
Matched Iupac: … 1-({[1,1'-biphenyl]-4-yl}(phenyl)methyl)-1H-imidazole …
Matched Mixtures name: … CANESTEN ULTRA UÑAS 1% …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Imidazole and Triazole Derivatives …
Matched Products: … ANTIZOX® 1% CREMA ... MYCOSPOR POLVO 1 G. ... MYCOSPOR POLVO AL 1% …
Matched Iupac: … 1-({[1,1'-biphenyl]-4-yl}(phenyl)methyl)-1H-imidazole …
Matched Mixtures name: … CANESTEN ULTRA UÑAS 1% …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Imidazole and Triazole Derivatives …
Matched Products: … ANTIZOX® 1% CREMA ... MYCOSPOR POLVO 1 G. ... MYCOSPOR POLVO AL 1% …
Migalastat
Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys,...
Approved
Investigational
Matched Synonyms: … 1-Deoxygalactostatin ... 1-Deoxygalactonojirimycin …
Matched Description: … in patients with Fabry disease, builds up in the blood vessels, the kidneys, the nerves, the heart, and ... L4274,L4278] In the U.S., it is estimated that more than 3,000 people are living with Fabry disease, and ... [L4274] Given the rarity of Fabry disease and the proportion of Fabry disease patients that could …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Description: … in patients with Fabry disease, builds up in the blood vessels, the kidneys, the nerves, the heart, and ... L4274,L4278] In the U.S., it is estimated that more than 3,000 people are living with Fabry disease, and ... [L4274] Given the rarity of Fabry disease and the proportion of Fabry disease patients that could …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Domperidone
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Synonyms: … 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone ... 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2 ... 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2 …
Matched Iupac: … 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 …
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Salts cas: … 83898-65-1 …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 1-Ring …
Matched Products: … MOTILIUM SUSPENSION 1 mg/ml ... NORINPEP® SUSPENSION 1 MG/ML ... DOMPERIDONA SUSPENSION 1 MG/ML …
Matched Iupac: … 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 …
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Salts cas: … 83898-65-1 …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 1-Ring …
Matched Products: … MOTILIUM SUSPENSION 1 mg/ml ... NORINPEP® SUSPENSION 1 MG/ML ... DOMPERIDONA SUSPENSION 1 MG/ML …
Secnidazole
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Synonyms: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2 ol ... 1-(2 hydroxypropyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … to form a radical anion, thereby damaging and killing the target pathogen. ... It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays ... improved oral absorption and a longer terminal elimination half-life than other drugs in this class. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... azithromycin, fluconazole and secnidazole ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … SEDIL 1 G. ... SECNIDAZOL 1 G ... NIDAZ®TABLETA 1 G …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … to form a radical anion, thereby damaging and killing the target pathogen. ... It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays ... improved oral absorption and a longer terminal elimination half-life than other drugs in this class. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... azithromycin, fluconazole and secnidazole ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … SEDIL 1 G. ... SECNIDAZOL 1 G ... NIDAZ®TABLETA 1 G …
Methysergide
An ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the...
Approved
Matched Synonyms: … (+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide ... 1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide ... N-(1-(Hydroxymethyl)propyl)-1-methyl-dextro-(+)-lysergamide …
Matched Iupac: … (4R,7R)-N-(1-hydroxybutan-2-yl)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1 …
Matched Description: … Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …
Matched Categories: … Ergot Alkaloids and Derivatives …
Matched Iupac: … (4R,7R)-N-(1-hydroxybutan-2-yl)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1 …
Matched Description: … Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …
Matched Categories: … Ergot Alkaloids and Derivatives …
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