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Displaying drugs 1 - 25 of 10312 in total
Meningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup Y. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup Y.
Approved
Experimental
Investigational
Matched Synonyms: … Meningococcal polysaccharide antigen group Y ... Neisseria meningitidis group Y polysaccharide antigen, A ... Neisseria meningitidis group Y capsular polysaccharide antigen …
Matched Name: … Meningococcal polysaccharide vaccine group Y …
Matched Description: … Meningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified ... It is subcutaneously administered as an active immunization against the invasive meningococcal disease …
Approved
Matched Synonyms: … Nimenrix component neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Name: … Neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen …
Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup c. The vaccine contains N. meningitis serogroup c capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Name: … Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen …
Matched Description: … Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active …
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-cells are collected from the patient, they are genetically engineered to express...
Approved
Matched Synonyms: … Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen …
Matched Description: … [L40054] The development of resulted from early preclinical studies conducted by a group of researchers ... Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. ... [A216163] Axicabtagene ciloleucel was approved by the FDA on October 18th, 2017. …
Matched Categories: … Antineoplastic Agents ... Antineoplastic Agents, Immunological ... Antineoplastic and Immunomodulating Agents
Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. Like other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way...
Approved
Matched Synonyms: … AN-MDP …
Approved
Experimental
Matched Products: … Truemed Group LLC …
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Categories: … Antihypertensive Agents ... Cardiovascular Agents ... Hypotensive Agents ... Vasodilating Agents ... Hypoglycemia-Treating Agents
Matched Products: … Truemed Group LLC …
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Approved
Vet approved
Matched Description: … It is used in allergies and as an antitussive, antiemetic, and hypnotic. …
Matched Categories: … Autonomic Agents ... Histamine Agents ... Anticholinergic Agents ... Agents producing tachycardia ... Gastrointestinal Agents
Matched Products: … Aldex AN
A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Categories: … Sensory System Agents ... Central Nervous System Agents ... Peripheral Nervous System Agents ... Methemoglobinemia Associated Agents
Matched Products: … Truemed Group LLC …
Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Approved
Matched Categories: … Hematologic Agents
Matched Products: … Truemed Group LLC …
Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower...
Approved
Investigational
Matched Description: … Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins ... Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 …
Matched Categories: … Hematologic Agents ... Agents causing hyperkalemia …
The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material. Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.[L5605,...
Approved
Matched Description: … [T484] The currently approved product of conjugated estrogens was developed by Wyeth Ayerst and FDA approved ... [T475] The conjugated estrogen mixture was approved for marketing in US in 1942 based on the efficacy …
Matched Categories: … Agents causing angioedema …
Matched Products: … Truemed Group LLC …
Foreskin fibroblast-like stromal cells (FDSCs) are progenitors isolated from human tissue that can differentiate into various cell types . Also known as Dermagraft, this device is a cryopreserved human fibroblast-derived dermal substitute. Composed of fibroblasts, extracellular matrix, and a bioabsorbable scaffold, it effectively supports wound healing . Dermagraft has only...
Approved
Matched Description: … Dermagraft has only been available in the United States as an investigational device (IDE). ... Dermagraft for the treatment of diabetic foot ulcers was approved for sale in Canada in 1997. …
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Description: … [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Antiparasitic Agents ... QTc Prolonging Agents ... Agents that reduce seizure threshold …
Matched Products: … Truemed Group LLC …
Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.
Approved
Investigational
Matched Categories: … Antiarrhythmic agents ... Cardiotonic Agents ... Protective Agents ... Hypotensive Agents ... Cardiovascular Agents
Indecainide is a rarely used antidysrhythmic. Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.
Approved
Matched Description: … Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of ... antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics …
Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... nonionic iodinated contrast agents. ... [A263096] Approved by the FDA in 1993, gadodiamide is the first non-ionic GBCA to be used. …
Matched Categories: … Miscellaneous Therapeutic Agents
Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved
Matched Description: … It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel ... Although it is not a currently approved drug by the FDA, pinaverium is available in over 60 countries …
Matched Categories: … Autonomic Agents ... Antiarrhythmic agents ... Cardiovascular Agents ... Agents causing hyperkalemia ... Vasodilating Agents
Matched Products: … Truemed Group LLC …
An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Approved
Investigational
Matched Description: … An antibiotic that is produced by Stretomyces achromogenes. ... It is used as an antineoplastic agent and to induce diabetes in experimental animals. …
Matched Categories: … Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Antineoplastic Agents, Alkylating ... Antineoplastic and Immunomodulating Agents
A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Categories: … Cardiovascular Agents ... Hypotensive Agents ... Natriuretic Agents ... Agents causing hyperkalemia …
Eptinezumab is a fully-humanized IgG1 antibody manufactured using yeast (Pichia pastoris) and developed by Lundbeck Seattle Biopharmaceuticals. Eptinezumab has been specifically designed to bind to both alpha and beta forms of the human calcitonin gene-related peptide (CGRP).[F94,A33105,A33106,A33108] It was approved by the FDA in February 2020 for the preventive treatment...
Approved
Investigational
Matched Description: … [F94,A33105,A33106,A33108] It was approved by the FDA in February 2020 for the preventive treatment of …
Potassium alum is considered by the FDA as a generally recognized as safe (GRAS) substance. It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that is predominantly produced in the dodecahydrate form (AlK(SO4)2 * 12H2O). Potassium alum is formed by large, transparent crystals that...
Approved
Matched Description: … [L1070] It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that …
Pirfenidone is a synthetic pyridone drug. It is an antifibrotic agent with anti-inflammatory and antioxidant properties that is used to treat idiopathic pulmonary fibrosis (IPF), which is a chronic, progressive form of interstitial pneumonia. While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate...
Approved
Investigational
Matched Description: … [A251370] It is an antifibrotic agent with anti-inflammatory and antioxidant properties [A251370] that ... [A251365] The FDA first approved pirfenidone alongside [nintedanib] as one of the first drugs to treat …
Matched Categories: … Antifibrotic Agents ... Antineoplastic Agents ... Antirheumatic Agents ... Anti-Inflammatory Agents ... Sensory System Agents
Matched Products: … Truemed Group LLC …
Displaying drugs 1 - 25 of 10312 in total