Voltage-dependent T-type calcium channel subunit alpha-1H

BE0000864ProteinHumansCACNA1H

Voltage-sensitive calcium channel that gives rise to T-type calcium currents. It is acted on by 23 drugs in DrugBank.

Gene name
CACNA1H
UniProtKB entry
O95180Swiss-Prot
Cellular location
Cell membrane
Residues / weight
2,353 residues · 259,160 Da
Also known as
Low-voltage-activated calcium channel alpha1 3.2 subunit · Voltage-gated calcium channel subunit alpha Cav3.2

Resolves to

Protein
UniProtO95180UniProt nameCAC1H_HUMAN
Gene
HGNCHGNC:1395NCBI Gene8912GenBank14670397GeneCardsCACNA1H
Pharmacology
IUPHAR/GtoPdb536KEGGhsa:8912
Structure
PDB9AYGPDB9AYHPDB9AYJ
Drugs

What you can answer from here — as of September 07, 2019

23DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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64+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Voltage-dependent T-type calcium channel subunit alpha-1H, how selective are they, and which programs against it are still in active trials?

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