Carbonic anhydrase 9

BE0002437ProteinHumansCA9

Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). It is acted on by 31 drugs in DrugBank.

Gene name
CA9
UniProtKB entry
Q16790Swiss-Prot
Cellular location
Nucleus
Residues / weight
459 residues · 49,697 Da
Also known as
4.2.1.1 · CA-IX · CAIX · Carbonate dehydratase IX · Carbonic anhydrase IX

Resolves to

Protein
UniProtQ16790UniProt nameCAH9_HUMAN
Gene
HGNCHGNC:1383NCBI Gene768GeneCardsCA9
Pharmacology
IUPHAR/GtoPdb3055KEGGhsa:768
Structure
PDB2HKFPDB3IAIPDB5DVX
Drugs

What you can answer from here — as of September 07, 2019

31DrugsApproved to experimental, with action, bond type and pharmacological action
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7Clinical trialsTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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104+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Carbonic anhydrase 9, how selective are they, and which programs against it are still in active trials?

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