Steroids, Fluorinated

Name
Steroids, Fluorinated
Accession Number
DBCAT000749
Description

Steroids which are substituted with one or more fluorine atoms in any position.

Drugs
DrugDrug Description
AmcinonideA topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Betamethasone phosphateA fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions.
ClobetasolClobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
Clobetasol propionateA corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis.
ClobetasoneA corticosteroid used to treat dry eyes, eczema, and dermatitis.
ClocortoloneA corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp.
Clocortolone acetateNot Annotated
DesoximetasoneA glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions. Developed in 1957, dexamethasone is...
Dexamethasone isonicotinateDexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
Dexamethasone metasulfobenzoateAn ophthalmic and auricular corticosteroid used with antibiotics for the treatment of otitis externa, blepharitis, and other inflammatory eye conditions.
Dexamethasone palmitateDexamethasone palmitate is under investigation in clinical trial NCT05693467 (Preemptive Co-infiltration of Dexamethasone Palmitate With Ropivacaine for Postoperative Pain in Major Spinal Surgery).
DiflorasoneA topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort.
DifluocortoloneA topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
DifluprednateA topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery.
FlumethasoneA corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions.
FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
Flunisolide acetateNot Annotated
FluocinoloneFluocinolone has been used in trials studying the treatment and prevention of Candida Infection, Oral Lichen Planus, Macular Degeneration, and Choroidal Neovascularization.
Fluocinolone acetonideA corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
FluocinonideA high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
FluocortoloneA glucocorticoid used topically for localized skin reactions and also orally for systemic use.
Fluocortolone caproateA corticosteroid indicated in the treatment of hemorrhoids, anal fissures, and corticosteroid-responsive dermatoses.
Fluocortolone pivalateA corticosteroid used to treat corticosteroid-responsive dermatoses and hemorrhoids.
FluorometholoneAn ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
FluoxymesteroneA synthetic androgenic anabolic steroid that used in the treatment of hypogonadism and delayed puberty in males, as well as breast neoplasms in women.
FluprednisoloneA synthetic glucocorticoid with anti-inflammatory properties.
FlurandrenolideA corticosteroid used to treat corticosteroid-responsive dermatoses.
HalometasoneA corticosteroid indicated in the treatment of corticosteroid responsive dermatoses.
IsoflupredoneNot Annotated
Isoflupredone acetateNot Annotated
ParamethasoneFor the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary...
Paramethasone acetateNot Annotated
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
UlobetasolA lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Drugs & Drug Targets
DrugTargetType
AmcinonideGlucocorticoid receptortarget
AmcinonideAnnexin A1target
AmcinonideCytochrome P450 3A4enzyme
AmcinonideCytochrome P450 3A5enzyme
AmcinonideSteroid hormone receptor ERR1target
AmcinonideSteroid hormone receptor ERR2target
AmcinonideEstrogen-related receptor gammatarget
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCorticosteroid-binding globulincarrier
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneATP-dependent translocase ABCB1transporter
BetamethasoneAromataseenzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneAlbumincarrier
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
Betamethasone phosphateGlucocorticoid receptortarget
Betamethasone phosphateCytochrome P450 3A4enzyme
Betamethasone phosphateCytochrome P450 3A5enzyme
Betamethasone phosphateAnnexin A1target
Betamethasone phosphateCorticosteroid-binding globulincarrier
Betamethasone phosphateAlbumincarrier
Betamethasone phosphateSolute carrier organic anion transporter family member 1A2transporter
Betamethasone phosphateOrganic anion transporter 3transporter
Betamethasone phosphateATP-dependent translocase ABCB1transporter
ClobetasolPhospholipase A2target
ClobetasolCytochrome P450 3A5enzyme
ClobetasolCytochrome P450 3A4enzyme
Clobetasol propionateGlucocorticoid receptortarget
Clobetasol propionateAlbumincarrier
Clobetasol propionateCorticosteroid-binding globulincarrier
Clobetasol propionateMineralocorticoid receptortarget
Clobetasol propionateAnnexin A1target
Clobetasol propionateCytochrome P450 3A5enzyme
Clobetasol propionateCytochrome P450 3A4enzyme
ClobetasoneCytochrome P450 3A4enzyme
ClobetasoneGlucocorticoid receptortarget
ClocortolonePhospholipase A2target
ClocortoloneGlucocorticoid receptortarget
Clocortolone acetateCytochrome P450 3A4enzyme
Clocortolone acetateCytochrome P450 3A5enzyme
DesoximetasoneEstrogen-related receptor gammatarget
DesoximetasoneSteroid hormone receptor ERR2target
DesoximetasoneGlucocorticoid receptortarget
DesoximetasoneSteroid hormone receptor ERR1target
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DexamethasoneATP-binding cassette sub-family C member 2transporter
DexamethasoneATP-dependent translocase ABCB1transporter
DexamethasoneBile salt export pumptransporter
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneAlbumincarrier
Dexamethasone11-beta-hydroxysteroid dehydrogenase type 2enzyme
Dexamethasone11-beta-hydroxysteroid dehydrogenase 1enzyme
DexamethasoneOrganic anion transporter 3transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneAnnexin A1target
DexamethasoneGlucocorticoid receptortarget
Dexamethasone acetateCytochrome P450 2C19enzyme
Dexamethasone acetateCytochrome P450 2B6enzyme
Dexamethasone acetateCytochrome P450 2A6enzyme
Dexamethasone acetateCytochrome P450 1A1enzyme
Dexamethasone acetateSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
Dexamethasone acetateBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
Dexamethasone acetateSolute carrier organic anion transporter family member 1A2transporter
Dexamethasone acetateATP-binding cassette sub-family C member 2transporter
Dexamethasone acetateATP-dependent translocase ABCB1transporter
Dexamethasone acetateBile salt export pumptransporter
Dexamethasone acetateCytochrome P450 3A7enzyme
Dexamethasone acetateCytochrome P450 3A5enzyme
Dexamethasone acetateCytochrome P450 3A4enzyme
Dexamethasone acetateNuclear receptor subfamily 0 group B member 1target
Dexamethasone acetateNitric oxide synthase, inducibletarget
Dexamethasone acetateAnnexin A1target
Dexamethasone acetateGlucocorticoid receptortarget
Dexamethasone acetateCytochrome P450 2C8enzyme
Dexamethasone acetateCytochrome P450 2E1enzyme
Dexamethasone acetateCytochrome P450 3A43enzyme
Dexamethasone acetateCytochrome P450 4A11enzyme
Dexamethasone acetateNuclear receptor subfamily 1 group I member 2target
Dexamethasone acetateCytochrome P450 11B1, mitochondrialenzyme
Dexamethasone acetateAlbumincarrier
Dexamethasone acetate11-beta-hydroxysteroid dehydrogenase type 2enzyme
Dexamethasone acetate11-beta-hydroxysteroid dehydrogenase 1enzyme
Dexamethasone acetateOrganic anion transporter 3transporter
Dexamethasone isonicotinateCytochrome P450 3A4enzyme
Dexamethasone isonicotinateCytochrome P450 3A5enzyme
Dexamethasone palmitateSteroid hormone receptor ERR1target
DiflorasoneGlucocorticoid receptortarget
DiflorasonePhospholipase A2target
DifluocortoloneAnnexin A3target
DifluocortoloneCytochrome P450 3A5enzyme
DifluocortoloneCytochrome P450 3A4enzyme
DifluocortoloneGlucocorticoid receptortarget
DifluprednateAnnexin A1target
DifluprednateCytochrome P450 3A4enzyme
DifluprednateGlucocorticoid receptortarget
FlumethasoneCorticosteroid-binding globulincarrier
FlumethasoneGlucocorticoid receptortarget
FlumethasoneCytochrome P450 3A4enzyme
FlumethasoneSteroid hormone receptor ERR1target
FlumethasoneSteroid hormone receptor ERR2target
FlumethasoneEstrogen-related receptor gammatarget
FlunisolideCorticosteroid-binding globulincarrier
FlunisolideCytochrome P450 3A4enzyme
FlunisolideGlucocorticoid receptortarget
FluocinoloneGlucocorticoid receptortarget
Fluocinolone acetonideAnnexin A2target
Fluocinolone acetonideAnnexin A3target
Fluocinolone acetonideCytochrome P450 3A4enzyme
Fluocinolone acetonideGlucocorticoid receptortarget
Fluocinolone acetonideCorticosteroid-binding globulincarrier
Fluocinolone acetonideAnnexin A1target
Fluocinolone acetonideAnnexin A4target
Fluocinolone acetonideAnnexin A5target
Fluocinolone acetonidePhospholipase A2target
FluocinonideSteroid hormone receptor ERR2target
FluocinonideGlucocorticoid receptortarget
FluocinonideSteroid hormone receptor ERR1target
FluocinonideCytochrome P450 3A5enzyme
FluocinonideCytochrome P450 3A4enzyme
FluocinonideCorticosteroid-binding globulincarrier
FluocinonideEstrogen-related receptor gammatarget
FluocinonideProtein smoothenedtarget
FluocortoloneCytochrome P450 3A4enzyme
FluocortoloneCytochrome P450 3A5enzyme
FluocortoloneAlbumincarrier
FluocortoloneCorticosteroid-binding globulincarrier
FluorometholoneCytochrome P450 3A4enzyme
FluorometholoneGlucocorticoid receptortarget
FluorometholoneCytochrome P450 3A5enzyme
FluorometholoneCorticosteroid-binding globulincarrier
FluoxymesteroneSex hormone-binding globulincarrier
FluoxymesteroneEstrogen receptortarget
FluoxymesteroneAndrogen receptortarget
FluoxymesteroneGlucocorticoid receptortarget
Fluoxymesterone11-beta-hydroxysteroid dehydrogenase type 2target
FluprednisoloneCytochrome P450 3A4enzyme
FluprednisoloneGlucocorticoid receptortarget
FlurandrenolideEstrogen-related receptor gammatarget
FlurandrenolideSteroid hormone receptor ERR2target
FlurandrenolideSteroid hormone receptor ERR1target
FlurandrenolideCytochrome P450 3A4enzyme
FlurandrenolideGlucocorticoid receptortarget
FlurandrenolideCorticosteroid-binding globulincarrier
HalometasoneCytochrome P450 3A4enzyme
HalometasoneCytochrome P450 3A5enzyme
HalometasoneGlucocorticoid receptortarget
ParamethasoneGlucocorticoid receptortarget
ParamethasoneCorticosteroid-binding globulincarrier
ParamethasoneCytochrome P450 3A4enzyme
ParamethasoneCorticosteroid-binding globulintarget
ParamethasoneCytochrome P450 3A5enzyme
Paramethasone acetateGlucocorticoid receptortarget
TriamcinoloneCytochrome P450 3A5enzyme
TriamcinoloneCytochrome P450 3A7enzyme
TriamcinoloneAlbumincarrier
TriamcinoloneProstaglandin G/H synthase 2enzyme
TriamcinoloneCytochrome P450 3A4enzyme
TriamcinoloneGlucocorticoid receptortarget
TriamcinoloneCholinesteraseenzyme
TriamcinoloneCorticosteroid-binding globulincarrier
UlobetasolGlucocorticoid receptortarget
UlobetasolEstrogen-related receptor gammatarget
UlobetasolSteroid hormone receptor ERR2target
UlobetasolSteroid hormone receptor ERR1target
UlobetasolCorticosteroid-binding globulincarrier