Antiinfectives and Antiseptics for Local Oral Treatment

Name
Antiinfectives and Antiseptics for Local Oral Treatment
Accession Number
DBCAT002259
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
OxyquinolineA medication used in combination with other medications to restore vaginal pH.
DomiphenAnti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions.
Perboric acidIn the industry, sodium perborate is used as a disinfectant. It is also part of the ingredients for detergents, bleach powders, and personal care formulations. In cosmetic products, perboric acid...
BenzoxoniumAn antiseptic indicated in skin disinfection and prevention of infections.
Tibezonium iodideNot Annotated
DoxycyclineA tetracycline antibiotic used to treat a wide variety of bacterial infections.
Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
TetracyclineAn antibiotic used to treat a wide variety of susceptible infections.
NatamycinA macrolide antifungal used to treat fungal infections of the eye.
ChlorhexidineAn antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.
MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
MinocyclineA tetracycline analog used to treat a wide variety of infections in the body.
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
HexetidineAn topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa.
ChlortetracyclineThe first tetracycline antibiotic most commonly used for veterinary purposes.
Hydrogen peroxideA compound used as a disinfectant and sterilizer.
MepartricinA medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis.
Drugs & Drug Targets
DrugTargetType
ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
ClotrimazoleCytochrome P450 2D6enzyme
ClotrimazoleCytochrome P450 2C8enzyme
ClotrimazoleCytochrome P450 3A4enzyme
ClotrimazoleCytochrome P450 2B6enzyme
ClotrimazoleP-glycoprotein 1transporter
ClotrimazoleCytochrome P450 2A6enzyme
ClotrimazoleCytochrome P450 2C9enzyme
ClotrimazoleCytochrome P450 2E1enzyme
ClotrimazoleCytochrome P450 3A7enzyme
ClotrimazoleCytochrome P450 51target
ClotrimazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleHydroxycarboxylic acid receptor 2target
ClotrimazoleBile salt export pumptransporter
ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
ClotrimazoleErgosteroltarget
Doxycycline16S ribosomal RNAtarget
DoxycyclineSolute carrier family 22 member 6transporter
DoxycyclineCytochrome P450 3A4enzyme
DoxycyclineATP-binding cassette sub-family B member 5transporter
Amphotericin BErgosteroltarget
Tetracycline16S ribosomal RNAtarget
TetracyclineMajor prion proteintarget
TetracyclineSerum albumincarrier
TetracyclineCytochrome P450 3A4enzyme
TetracyclineSolute carrier family 22 member 6transporter
TetracyclineSolute carrier family 22 member 8transporter
TetracyclineSolute carrier family 22 member 11transporter
TetracyclineSolute carrier family 22 member 7transporter
Tetracycline30S ribosomal protein S3target
Tetracycline30S ribosomal protein S8target
Tetracycline30S ribosomal protein S19target
Tetracycline30S ribosomal protein S14target
Tetracycline30S ribosomal protein S7target
TetracyclineMultidrug translocase MdfAtarget
TetracyclineProtein-arginine deiminase type-4target
TetracyclineSolute carrier organic anion transporter family member 2B1transporter
NatamycinErgosteroltarget
ChlorhexidineBacterial outer membranetarget
ChlorhexidineSerum albumincarrier
MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
MetronidazoleCytochrome P450 2C9enzyme
MetronidazoleCytochrome P450 3A4enzyme
MetronidazoleCytochrome P450 2C8enzyme
MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
MetronidazoleAnaerobic bacterial DNAtarget
MetronidazoleProtozoal DNAtarget
MetronidazoleP-glycoprotein 1transporter
MetronidazoleCytochrome P450 2A6enzyme
MetronidazoleCytochrome P450 3A5enzyme
MetronidazoleCytochrome P450 3A7enzyme
Neomycin30S ribosomal protein S12target
Neomycin16S ribosomal RNAtarget
NeomycinExtracellular calcium-sensing receptortarget
Minocycline30S ribosomal protein S4target
Minocycline30S ribosomal protein S9target
Minocycline16S ribosomal RNAtarget
MinocyclineInterleukin-1 betatarget
MinocyclineArachidonate 5-lipoxygenasetarget
MinocyclineMatrix metalloproteinase-9target
MinocyclineVascular endothelial growth factor Atarget
MinocyclineCaspase-1target
MinocyclineCaspase-3target
MinocyclineCytochrome ctarget
MinocyclineSolute carrier family 22 member 6transporter
MinocyclineSolute carrier family 22 member 7transporter
MinocyclineOuter membrane protein Ftransporter
MinocyclineOuter membrane porin Ctransporter
MinocyclineMitogen-activated Protein Kinasestarget
MinocyclineNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
Chlortetracycline16S ribosomal RNAtarget
ChlortetracyclineSerum albumincarrier
Chlortetracycline30S ribosomal protein S3target
Chlortetracycline30S ribosomal protein S8target
Chlortetracycline30S ribosomal protein S19target
Chlortetracycline30S ribosomal protein S14target
Chlortetracycline30S ribosomal protein S7target
Hydrogen peroxideGlutathione peroxidase 1enzyme
Hydrogen peroxideCatalaseenzyme
Hydrogen peroxideAlkaline phosphatase, placental-likeenzyme