BSEP/ABCB11 Substrates

Name
BSEP/ABCB11 Substrates
Accession Number
DBCAT003979
Description
Not Available
Drugs
DrugDrug Description
Ursodeoxycholic acidA bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients.
Taurocholic acidThe product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats...
Cholic AcidA bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function.
Glycochenodeoxycholic AcidA bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed....
VinblastineA vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
PaclitaxelA taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
DoxorubicinA medication used to treat various cancers and Kaposi's Sarcoma.
DaunorubicinAn anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
FluoresceinA dye used in angiography or angioscopy of the iris and retina.
VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
DigoxinA cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation.
PravastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
TipranavirA protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.
TelmisartanAn ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
Indocyanine green acid formA diagnostic agent used for the determination of cardiac output, hepatic function and liver blood flow, and for ophthalmic angiography.
NefazodoneAn antidepressant used in the treatment of depression.
SaquinavirAn HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
GlyburideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
MifepristoneA cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation.
LoratadineA second generation antihistamine used to manage the symptoms of allergic rhinitis.
DihydroergocristineAn ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's.
BenzbromaroneBenzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.
NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
LovastatinAn HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.
FelodipineA calcium channel blocker used to treat hypertension.
DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
LosartanAn angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
GlimepirideA sulfonylurea drug used to treat type 2 diabetes mellitus.
DisulfiramA carbamate derivative used to treat alcohol addiction.
SimvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
SpironolactoneAn aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, hirsutism (off-label) and hypokalemia.
AtorvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
CerivastatinA statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events.
IsradipineA dihydropyridine calcium channel blocker used for the treatment of hypertension.
EzetimibeA cholesterol absorption inhibitor used to lower total cholesterol, LDL-C, Apo-B, and non-HDL-C in primary hyperlipidemia and familial cholesterolemia.
DipyridamoleA phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
PitavastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
FenofibrateA peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia.
AtazanavirAn antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
RepaglinideA antihyperglycemic used to improve glycemic control in diabetes.
SulfinpyrazoneA platelet inhibitory and uricosuric agent used to inhibit thrombotic and embolic processes and to manage the chronic phases of gout .
RanolazineAn anti-anginal drug used for the treatment of chronic angina.
RosiglitazoneA thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes.
NelfinavirA viral protease inhibitor used in the treatment of HIV infection.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
IndinavirA protease inhibitor used to treat HIV infection.
CefaclorA second generation cephalosporin used to treat a wide variety of infections in the body.
Prasterone sulfateInvestigated for use/treatment in asthma and burns and burn infections.
AstemizoleA second generation antihistamine used to treat allergy symptoms.
AmiodaroneA class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
PilsicainidePilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.
NitrofurantoinAn antibiotic used to treat urinary tract infections.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
FluvoxamineA selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
OfloxacinAn antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
GlipizideA sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release.
AtenololA synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients.
EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
TerfenadineFor the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
ClarithromycinA macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
Glycyrrhizic acidGlycyrrhizic acid is widely applied in foods as a natural sweetener. As a therapeutic agent, is has been used in a vast variety of formulations as it is reported to...
AtropineA muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
FlucloxacillinA narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA).
NitrendipineFor the treatment of mild to moderate hypertension
ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
SulfamethoxazoleAn oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
Belantamab mafodotinAn anti B-cell maturation antigen antibody conjugated to a microtubule inhibitor to treat relapsed or refractory multiple myeloma.
Drugs & Drug Targets
DrugTargetType
Ursodeoxycholic acidAldo-keto reductase family 1 member C2target
Ursodeoxycholic acidBile salt export pumptransporter
Ursodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Ursodeoxycholic acidCanalicular multispecific organic anion transporter 1transporter
Ursodeoxycholic acidMultidrug resistance-associated protein 4transporter
Ursodeoxycholic acidIleal sodium/bile acid cotransportertransporter
Ursodeoxycholic acidSodium/bile acid cotransportertransporter
Ursodeoxycholic acidCytochrome P450 2E1enzyme
Ursodeoxycholic acidBile acid receptortarget
Taurocholic acidBile salt-activated lipasetarget
Taurocholic acidGastrotropintarget
Taurocholic acidBile salt export pumptransporter
Taurocholic acidMultidrug resistance-associated protein 1transporter
Taurocholic acidSolute carrier organic anion transporter family member 1A2transporter
Taurocholic acidIleal sodium/bile acid cotransportertransporter
Taurocholic acidCanalicular multispecific organic anion transporter 1transporter
Taurocholic acidSolute carrier organic anion transporter family member 1B1transporter
Taurocholic acidCanalicular multispecific organic anion transporter 2transporter
Taurocholic acidMultidrug resistance-associated protein 4transporter
Taurocholic acidP-glycoprotein 1transporter
Taurocholic acidSolute carrier family 22 member 6transporter
Taurocholic acidMultidrug resistance-associated protein 7transporter
Taurocholic acidSolute carrier family 22 member 8transporter
Taurocholic acidSolute carrier organic anion transporter family member 4A1transporter
Taurocholic acidATP-binding cassette sub-family C member 11transporter
Taurocholic acidSolute carrier organic anion transporter family member 1C1transporter
Taurocholic acidSolute carrier organic anion transporter family member 3A1transporter
Taurocholic acidATP-binding cassette sub-family G member 2transporter
Taurocholic acidSolute carrier organic anion transporter family member 2B1transporter
Taurocholic acidMonocarboxylate transporter 1transporter
Taurocholic acidSodium/bile acid cotransportertransporter
Taurocholic acidOrganic solute transporter subunit alphatransporter
Taurocholic acidOrganic solute transporter subunit betatransporter
Taurocholic acidSolute carrier organic anion transporter family member 1B3transporter
Taurocholic acidCystine/glutamate transportertransporter
Taurocholic acidBile acid receptortarget
Cholic AcidFerrochelatase, mitochondrialtarget
Cholic AcidBile salt export pumptransporter
Cholic AcidP-glycoprotein 1transporter
Cholic AcidMultidrug resistance-associated protein 1transporter
Cholic AcidSolute carrier organic anion transporter family member 1A2transporter
Cholic AcidIleal sodium/bile acid cotransportertransporter
Cholic AcidCanalicular multispecific organic anion transporter 1transporter
Cholic AcidSolute carrier organic anion transporter family member 1B1transporter
Cholic AcidCanalicular multispecific organic anion transporter 2transporter
Cholic AcidMultidrug resistance-associated protein 4transporter
Cholic AcidSodium/bile acid cotransportertransporter
Cholic AcidSolute carrier family 22 member 8transporter
Cholic AcidSolute carrier family 22 member 7transporter
Cholic AcidSolute carrier organic anion transporter family member 1B3transporter
Cholic AcidAlcohol dehydrogenase 1Ctarget
Cholic AcidEstrogen-related receptor gammatarget
Cholic AcidGastrotropintarget
Cholic AcidCytochrome c oxidase subunit 4 isoform 1, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 1target
Cholic AcidCytochrome c oxidase subunit 2target
Cholic AcidCytochrome c oxidase subunit 3target
Cholic AcidCytochrome c oxidase subunit 5A, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 5B, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 6Ctarget
Cholic AcidCytochrome c oxidase subunit 7B, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 7C, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 8A, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 6A2, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 6B1target
Cholic AcidCytochrome c oxidase subunit 7A1, mitochondrialtarget
Cholic AcidPhospholipase A2target
Cholic AcidLiver carboxylesterase 1target
Cholic AcidFatty acid-binding protein, livercarrier
Cholic AcidFerrochelatasetarget
Cholic AcidCholoylglycine hydrolasetarget
Cholic AcidBile acid receptortarget
Cholic AcidG-protein coupled bile acid receptor 1target
Glycochenodeoxycholic Acid7-alpha-hydroxysteroid dehydrogenasetarget
Glycochenodeoxycholic AcidBile salt export pumptransporter
Glycochenodeoxycholic AcidSolute carrier organic anion transporter family member 1A2transporter
Glycochenodeoxycholic AcidIleal sodium/bile acid cotransportertransporter
Glycochenodeoxycholic AcidSodium/bile acid cotransportertransporter
VinblastineTubulin beta chaintarget
VinblastineTranscription factor AP-1target
VinblastineCytochrome P450 3A4enzyme
VinblastineP-glycoprotein 1transporter
VinblastineMultidrug resistance-associated protein 1transporter
VinblastineCanalicular multispecific organic anion transporter 1transporter
VinblastineMultidrug resistance-associated protein 6transporter
VinblastineBile salt export pumptransporter
VinblastineTubulin alpha-1A chaintarget
VinblastineTubulin delta chaintarget
VinblastineTubulin epsilon chaintarget
VinblastineTubulin gamma-1 chaintarget
VinblastineCytochrome P450 2D6enzyme
VinblastineSolute carrier organic anion transporter family member 1B1transporter
PaclitaxelApoptosis regulator Bcl-2target
PaclitaxelTubulin beta-1 chaintarget
PaclitaxelCytochrome P450 2C8enzyme
PaclitaxelCytochrome P450 3A4enzyme
PaclitaxelCytochrome P450 3A5enzyme
PaclitaxelCytochrome P450 3A7enzyme
PaclitaxelBile salt export pumptransporter
PaclitaxelP-glycoprotein 1transporter
PaclitaxelMultidrug resistance-associated protein 1transporter
PaclitaxelMultidrug resistance-associated protein 7transporter
PaclitaxelCytochrome P450 19A1enzyme
PaclitaxelCytochrome P450 1B1enzyme
PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
PaclitaxelNuclear receptor subfamily 1 group I member 2target
PaclitaxelMicrotubule-associated protein 4target
PaclitaxelMicrotubule-associated protein 2target
PaclitaxelMicrotubule-associated protein tautarget
PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DoxorubicinDNA topoisomerase 2-alphatarget
DoxorubicinDNAtarget
DoxorubicinCytochrome P450 3A4enzyme
DoxorubicinCytochrome P450 2D6enzyme
DoxorubicinCytochrome P450 2B6enzyme
DoxorubicinP-glycoprotein 1transporter
DoxorubicinCanalicular multispecific organic anion transporter 2transporter
DoxorubicinMultidrug resistance-associated protein 6transporter
DoxorubicinMultidrug resistance-associated protein 1transporter
DoxorubicinMultidrug resistance-associated protein 7transporter
DoxorubicinATP-binding cassette sub-family G member 2transporter
DoxorubicinBile salt export pumptransporter
DoxorubicinSolute carrier family 22 member 16transporter
DoxorubicinATP-binding cassette sub-family B member 8, mitochondrialtransporter
DoxorubicinCytochrome P450 1B1enzyme
DoxorubicinCarbonyl reductase [NADPH] 1enzyme
DoxorubicinCarbonyl reductase [NADPH] 3enzyme
DoxorubicinAlcohol dehydrogenase [NADP(+)]enzyme
DoxorubicinAldo-keto reductase family 1 member C3enzyme
DoxorubicinNAD(P)H dehydrogenase [quinone] 1enzyme
DoxorubicinXanthine dehydrogenase/oxidaseenzyme
DoxorubicinNitric oxide synthase, endothelialenzyme
DoxorubicinNitric oxide synthase, inducibleenzyme
DoxorubicinNitric oxide synthase, brainenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialenzyme
DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialenzyme
DoxorubicinNADPH--cytochrome P450 reductaseenzyme
DoxorubicinRalA-binding protein 1transporter
DoxorubicinCanalicular multispecific organic anion transporter 1transporter
DoxorubicinSerum albumincarrier
DoxorubicinNucleolar and coiled-body phosphoprotein 1target
DaunorubicinDNAtarget
DaunorubicinXanthine dehydrogenase/oxidaseenzyme
DaunorubicinCytochrome P450 3A5enzyme
DaunorubicinNADPH--cytochrome P450 reductaseenzyme
DaunorubicinP-glycoprotein 1transporter
DaunorubicinMultidrug resistance-associated protein 1transporter
DaunorubicinCanalicular multispecific organic anion transporter 1transporter
DaunorubicinMultidrug resistance-associated protein 6transporter
DaunorubicinBile salt export pumptransporter
DaunorubicinMultidrug resistance-associated protein 7transporter
DaunorubicinATP-binding cassette sub-family G member 2transporter
DaunorubicinDNA topoisomerase 2-alphatarget
DaunorubicinDNA topoisomerase 2-betatarget
DaunorubicinCytochrome P450 1A1enzyme
DaunorubicinCytochrome P450 1B1enzyme
DaunorubicinCytochrome P450 3A4enzyme
FluoresceinIg kappa chain V-II region RPMI 6410target
FluoresceinDNAtarget
FluoresceinSolute carrier family 22 member 6transporter
FluoresceinBile salt export pumptransporter
FluoresceinMultidrug resistance-associated protein 1transporter
VincristineTubulin beta chaintarget
VincristineCytochrome P450 3A4enzyme
VincristineCytochrome P450 3A5enzyme
VincristineCytochrome P450 3A7enzyme
VincristineP-glycoprotein 1transporter
VincristineCanalicular multispecific organic anion transporter 2transporter
VincristineSolute carrier family 22 member 3transporter
VincristineMultidrug resistance-associated protein 1transporter
VincristineMultidrug resistance-associated protein 7transporter
VincristineCanalicular multispecific organic anion transporter 1transporter
VincristineBile salt export pumptransporter
VincristineATP-binding cassette sub-family G member 2transporter
VincristineTubulin alpha-4A chaintarget
VincristineRalA-binding protein 1transporter
VincristineSolute carrier organic anion transporter family member 1B1transporter
VincristineSolute carrier organic anion transporter family member 1B3transporter
DigoxinSodium/potassium-transporting ATPase subunit alpha-1target
DigoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DigoxinP-glycoprotein 1transporter
DigoxinSolute carrier organic anion transporter family member 4C1transporter
DigoxinBile salt export pumptransporter
DigoxinSolute carrier organic anion transporter family member 1A2transporter
DigoxinOrganic solute transporter subunit alphatransporter
DigoxinOrganic solute transporter subunit betatransporter
DigoxinSolute carrier organic anion transporter family member 1B1transporter
Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
PravastatinSolute carrier organic anion transporter family member 2B1transporter
PravastatinP-glycoprotein 1transporter
PravastatinSolute carrier organic anion transporter family member 1A2transporter
PravastatinSolute carrier family 22 member 6transporter
PravastatinSolute carrier family 22 member 8transporter
PravastatinCanalicular multispecific organic anion transporter 1transporter
PravastatinSolute carrier family 22 member 11transporter
PravastatinATP-binding cassette sub-family G member 2transporter
PravastatinSolute carrier family 22 member 7transporter
PravastatinSolute carrier organic anion transporter family member 1B1transporter
PravastatinMonocarboxylate transporter 1transporter
PravastatinBile salt export pumptransporter
PravastatinSolute carrier organic anion transporter family member 1B3transporter
PravastatinHistone deacetylase 2target
Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
RosuvastatinCytochrome P450 2C9enzyme
RosuvastatinMultidrug resistance-associated protein 4transporter
RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
RosuvastatinCystine/glutamate transportertransporter
RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
RosuvastatinBile salt export pumptransporter
RosuvastatinATP-binding cassette sub-family G member 2transporter
RosuvastatinSerum albumincarrier
RosuvastatinCanalicular multispecific organic anion transporter 1transporter
RosuvastatinSolute carrier family 22 member 8transporter
RosuvastatinSodium/bile acid cotransportertransporter
RosuvastatinIntegrin alpha-Ltarget
TipranavirHuman immunodeficiency virus type 1 proteasetarget
TipranavirCytochrome P450 3A4enzyme
TipranavirCytochrome P450 2D6enzyme
TipranavirCytochrome P450 2C19enzyme
TipranavirBile salt export pumptransporter
TipranavirUDP-glucuronosyltransferase 1-1enzyme
TipranavirSolute carrier organic anion transporter family member 2B1transporter
TipranavirSolute carrier organic anion transporter family member 1B1transporter
TipranavirSolute carrier organic anion transporter family member 1B3transporter
TipranavirP-glycoprotein 1transporter
TelmisartanType-1 angiotensin II receptortarget
TelmisartanPeroxisome proliferator-activated receptor gammatarget
TelmisartanP-glycoprotein 1transporter
TelmisartanCanalicular multispecific organic anion transporter 1transporter
TelmisartanATP-binding cassette sub-family G member 2transporter
TelmisartanCytochrome P450 2C19enzyme
TelmisartanBile salt export pumptransporter
TelmisartanUDP-glucuronosyltransferase 1-3enzyme
ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
ClotrimazoleCytochrome P450 2D6enzyme
ClotrimazoleCytochrome P450 2C8enzyme
ClotrimazoleCytochrome P450 3A4enzyme
ClotrimazoleCytochrome P450 2B6enzyme
ClotrimazoleP-glycoprotein 1transporter
ClotrimazoleCytochrome P450 2A6enzyme
ClotrimazoleCytochrome P450 2C9enzyme
ClotrimazoleCytochrome P450 2E1enzyme
ClotrimazoleCytochrome P450 3A7enzyme
ClotrimazoleCytochrome P450 51target
ClotrimazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleHydroxycarboxylic acid receptor 2target
ClotrimazoleBile salt export pumptransporter
ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
ClotrimazoleErgosteroltarget
Indocyanine green acid formCanalicular multispecific organic anion transporter 1transporter
Indocyanine green acid formIsocitrate dehydrogenase [NADP] cytoplasmicenzyme
Indocyanine green acid formGlutaminase kidney isoform, mitochondrialenzyme
Indocyanine green acid formBile salt export pumptransporter
Nefazodone5-hydroxytryptamine receptor 2Atarget
NefazodoneSodium-dependent serotonin transportertarget
NefazodoneSodium-dependent noradrenaline transportertarget
NefazodoneAlpha-1A adrenergic receptortarget
NefazodoneAlpha-1B adrenergic receptortarget
NefazodoneCytochrome P450 3A4enzyme
NefazodoneCytochrome P450 2D6enzyme
NefazodoneSodium-dependent dopamine transportertarget
NefazodoneAlpha-2A adrenergic receptortarget
Nefazodone5-hydroxytryptamine receptor 1Atarget
NefazodoneCYP2B proteinenzyme
NefazodoneP-glycoprotein 1transporter
Nefazodone5-hydroxytryptamine receptor 2Ctarget
NefazodonePotassium voltage-gated channel subfamily H member 2target
NefazodoneCytochrome P450 3A Subfamilyenzyme
NefazodoneSolute carrier organic anion transporter family member 1B3transporter
NefazodoneSolute carrier organic anion transporter family member 2B1transporter
NefazodoneBile salt export pumptransporter
SaquinavirHuman immunodeficiency virus type 1 proteasetarget
SaquinavirCytochrome P450 3A4enzyme
SaquinavirCytochrome P450 3A5enzyme
SaquinavirAlpha-1-acid glycoprotein 1carrier
SaquinavirSerum albumincarrier
SaquinavirCytochrome P450 3A7enzyme
SaquinavirP-glycoprotein 1transporter
SaquinavirSolute carrier family 22 member 1transporter
SaquinavirSolute carrier organic anion transporter family member 1A2transporter
SaquinavirATP-binding cassette sub-family G member 2transporter
SaquinavirSolute carrier organic anion transporter family member 1B1transporter
SaquinavirMultidrug resistance-associated protein 1transporter
SaquinavirCanalicular multispecific organic anion transporter 1transporter
SaquinavirCytochrome P450 2C8enzyme
SaquinavirCytochrome P450 2D6enzyme
SaquinavirSolute carrier organic anion transporter family member 2B1transporter
SaquinavirBile salt export pumptransporter
GlyburideATP-binding cassette sub-family C member 9target
GlyburideBile salt export pumptarget
GlyburideATP-binding cassette sub-family A member 1target
GlyburideCystic fibrosis transmembrane conductance regulatortarget
GlyburideSulfonylurea receptor 1, Kir6.2target
GlyburideCytochrome P450 2C9enzyme
GlyburideCanalicular multispecific organic anion transporter 2transporter
GlyburideBile salt export pumptransporter
GlyburideP-glycoprotein 1transporter
GlyburideMultidrug resistance-associated protein 1transporter
GlyburideSolute carrier family 15 member 1transporter
GlyburideSolute carrier organic anion transporter family member 1A2transporter
GlyburideSolute carrier family 15 member 2transporter
GlyburideSolute carrier family 22 member 6transporter
GlyburideCanalicular multispecific organic anion transporter 1transporter
GlyburideATP-binding cassette sub-family G member 2transporter
GlyburideSolute carrier family 22 member 7transporter
GlyburideSolute carrier organic anion transporter family member 2B1transporter
GlyburideCytochrome P450 2C19enzyme
GlyburideCytochrome P450 3A4enzyme
GlyburideSerum albumincarrier
GlyburideMitochondrial ATP-sensitive potassium channeltarget
GlyburideCarnitine O-palmitoyltransferase 1, liver isoformtarget
GlyburideCytochrome P450 3A7enzyme
GlyburideCytochrome P450 3A5enzyme
GlyburideTransient receptor potential cation channel subfamily M member 4target
KetoconazoleCytochrome P450 3A4enzyme
KetoconazoleCytochrome P450 2C9enzyme
KetoconazoleCytochrome P450 2C19enzyme
KetoconazoleCytochrome P450 3A5enzyme
KetoconazoleCytochrome P450 1A2enzyme
KetoconazoleCytochrome P450 2C8enzyme
KetoconazoleCytochrome P450 1A1enzyme
KetoconazoleCytochrome P450 2D6enzyme
KetoconazoleBile salt export pumptransporter
KetoconazoleP-glycoprotein 1transporter
KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
KetoconazoleCytochrome P450 1B1enzyme
KetoconazoleCytochrome P450 2A6enzyme
KetoconazoleCytochrome P450 2B6enzyme
KetoconazoleLanosterol 14-alpha demethylasetarget
KetoconazoleAndrogen receptortarget
KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
KetoconazoleSteroid 21-hydroxylasetarget
KetoconazolePotassium voltage-gated channel subfamily H member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 3target
KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
KetoconazoleCytochrome P450 4F12enzyme
KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
KetoconazoleSerum albumincarrier
KetoconazoleSex hormone-binding globulincarrier
KetoconazoleCytochrome P450 19A1enzyme
KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter
MifepristoneProgesterone receptortarget
MifepristoneGlucocorticoid receptortarget
MifepristoneCytochrome P450 3A4enzyme
MifepristoneCytochrome P450 3A5enzyme
MifepristoneP-glycoprotein 1transporter
MifepristoneMultidrug resistance-associated protein 1transporter
MifepristoneCytochrome P450 2D6enzyme
MifepristoneProstate-specific antigentarget
MifepristoneNuclear receptor subfamily 1 group I member 2target
MifepristoneBile salt export pumptransporter
MifepristoneCytochrome P450 2C8enzyme
MifepristoneCytochrome P450 2C9enzyme
MifepristoneSolute carrier organic anion transporter family member 1B1transporter
MifepristoneSolute carrier organic anion transporter family member 1B3transporter
LoratadineHistamine H1 receptortarget
LoratadineCytochrome P450 3A4enzyme
LoratadineCytochrome P450 2C19enzyme
LoratadineCytochrome P450 2D6enzyme
LoratadineCytochrome P450 2C8enzyme
LoratadineP-glycoprotein 1transporter
LoratadinePotassium voltage-gated channel subfamily H member 2target
LoratadineBile salt export pumptransporter
LoratadineCytochrome P450 1A1enzyme
LoratadineCytochrome P450 1A2enzyme
LoratadineCytochrome P450 2B6enzyme
LoratadineCytochrome P450 2C9enzyme
LoratadineCytochrome P450 3A5enzyme
LoratadineUDP-glucuronosyltransferase 2B10enzyme
LoratadineUDP-glucuronosyltransferase 1-1enzyme
LoratadineUDP-glucuronosyltransferase 1-3enzyme
LoratadineUDP-glucuronosyltransferase 2B15enzyme
DihydroergocristineSerotonin Receptorstarget
DihydroergocristineBeta adrenergic receptortarget
DihydroergocristineAlpha adrenergic receptortarget
DihydroergocristineDopamine receptortarget
DihydroergocristineBile salt export pumptransporter
DihydroergocristineCytochrome P450 3A4enzyme
BenzbromaroneCytochrome P450 2C9target
BenzbromaroneCytochrome P450 2C19target
BenzbromaroneSolute carrier organic anion transporter family member 1B1transporter
BenzbromaroneSolute carrier organic anion transporter family member 2B1transporter
BenzbromaroneBile salt export pumptransporter
BenzbromaroneCytochrome P450 2C19enzyme
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NicardipineCytochrome P450 3A4enzyme
NicardipineCytochrome P450 2C19enzyme
NicardipineCytochrome P450 2C8enzyme
NicardipineCytochrome P450 2D6enzyme
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
NicardipineAlpha-1A adrenergic receptortarget
NicardipineAlpha-1D adrenergic receptortarget
NicardipineAlpha-1B adrenergic receptortarget
NicardipineMuscarinic acetylcholine receptor M1target
NicardipineMuscarinic acetylcholine receptor M2target
NicardipineMuscarinic acetylcholine receptor M3target
NicardipineMuscarinic acetylcholine receptor M4target
NicardipineMuscarinic acetylcholine receptor M5target
NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NicardipineCalmodulintarget
NicardipineP-glycoprotein 1transporter
NicardipineCytochrome P450 2B6enzyme
NicardipineCytochrome P450 2E1enzyme
NicardipineCytochrome P450 3A5enzyme
NicardipineSolute carrier organic anion transporter family member 1B1transporter
NicardipineBile salt export pumptransporter
NicardipineCytochrome P450 2C9enzyme
Lovastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
LovastatinCytochrome P450 3A4enzyme
LovastatinCytochrome P450 2C8enzyme
LovastatinIntegrin alpha-Ltarget
LovastatinHistone deacetylase 2target
LovastatinSerum paraoxonase/lactonase 3enzyme
LovastatinP-glycoprotein 1transporter
LovastatinSolute carrier organic anion transporter family member 1A2transporter
LovastatinSolute carrier organic anion transporter family member 1B1transporter
LovastatinUDP-glucuronosyltransferase 1-1enzyme
LovastatinUDP-glucuronosyltransferase 1-3enzyme
LovastatinUDP-glucuronosyltransferase 2B7enzyme
LovastatinCanalicular multispecific organic anion transporter 1transporter
LovastatinBile salt export pumptransporter
LovastatinSerum albumincarrier
LovastatinCytochrome P450 2C19enzyme
LovastatinSolute carrier organic anion transporter family member 2B1transporter
LovastatinSolute carrier organic anion transporter family member 1B3transporter
FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
FelodipineCalmodulintarget
FelodipineCytochrome P450 3A4enzyme
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
FelodipineCytochrome P450 2C8enzyme
FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
FelodipineTroponin C, skeletal muscletarget
FelodipineTroponin C, slow skeletal and cardiac musclestarget
FelodipineMineralocorticoid receptortarget
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
FelodipineCytochrome P450 3A5enzyme
FelodipineCytochrome P450 3A7enzyme
FelodipineP-glycoprotein 1transporter
FelodipineCytochrome P450 2C9enzyme
FelodipineCytochrome P450 2D6enzyme
FelodipineBile salt export pumptransporter
DiethylstilbestrolEstrogen receptor alphatarget
DiethylstilbestrolEstrogen-related receptor gammatarget
DiethylstilbestrolTransthyretincarrier
DiethylstilbestrolCatechol O-methyltransferaseenzyme
DiethylstilbestrolCytochrome P450 19A1enzyme
DiethylstilbestrolATP-binding cassette sub-family G member 2transporter
DiethylstilbestrolP-glycoprotein 1transporter
DiethylstilbestrolEstrogen receptor betatarget
DiethylstilbestrolCytochrome P450 3A4enzyme
DiethylstilbestrolCytochrome P450 2C8enzyme
DiethylstilbestrolCytochrome P450 2C9enzyme
DiethylstilbestrolCytochrome P450 2E1enzyme
DiethylstilbestrolSteroid hormone receptor ERR1target
DiethylstilbestrolSteroid hormone receptor ERR2target
DiethylstilbestrolNuclear receptor coactivator 2target
DiethylstilbestrolNuclear receptor subfamily 1 group I member 2target
DiethylstilbestrolAndrogen receptortarget
DiethylstilbestrolSex hormone-binding globulintarget
DiethylstilbestrolSolute carrier organic anion transporter family member 1B1transporter
DiethylstilbestrolSolute carrier organic anion transporter family member 2B1transporter
DiethylstilbestrolBile salt export pumptransporter
LosartanType-1 angiotensin II receptortarget
LosartanCytochrome P450 3A4enzyme
LosartanCytochrome P450 2C9enzyme
LosartanP-glycoprotein 1transporter
LosartanSolute carrier family 22 member 6transporter
LosartanUDP-glucuronosyltransferase 1-1enzyme
LosartanUDP-glucuronosyltransferase 1-3enzyme
LosartanUDP-glucuronosyltransferase 1-10enzyme
LosartanUDP-glucuronosyltransferase 2B7enzyme
LosartanUDP-glucuronosyltransferase 2B17enzyme
LosartanCytochrome P450 2C19enzyme
LosartanSerum albumincarrier
LosartanSolute carrier family 22 member 12transporter
LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
LosartanBile salt export pumptransporter
LosartanCytochrome P450 2C8enzyme
GlimepirideATP-sensitive inward rectifier potassium channel 1target
GlimepirideATP-sensitive inward rectifier potassium channel 11target
GlimepirideCytochrome P450 2C9enzyme
GlimepirideATP-binding cassette sub-family C member 8target
GlimepirideBile salt export pumptransporter
DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DisulfiramCytochrome P450 2E1enzyme
DisulfiramDopamine beta-hydroxylasetarget
DisulfiramCytochrome P450 3A4enzyme
DisulfiramCytochrome P450 3A5enzyme
DisulfiramBile salt export pumptransporter
Simvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
SimvastatinCytochrome P450 3A4enzyme
SimvastatinCytochrome P450 2C8enzyme
SimvastatinCytochrome P450 2C9enzyme
SimvastatinCytochrome P450 3A5enzyme
SimvastatinP-glycoprotein 1transporter
SimvastatinSolute carrier organic anion transporter family member 1A2transporter
SimvastatinSolute carrier organic anion transporter family member 1B1transporter
SimvastatinCytochrome P450 2B6enzyme
SimvastatinCytochrome P450 2D6enzyme
SimvastatinUDP-glucuronosyltransferase 1-1enzyme
SimvastatinUDP-glucuronosyltransferase 1-3enzyme
SimvastatinUDP-glucuronosyltransferase 2B7enzyme
SimvastatinCanalicular multispecific organic anion transporter 1transporter
SimvastatinIntegrin alpha-Ltarget
SimvastatinBile salt export pumptransporter
SimvastatinCytochrome P450 2C19enzyme
SimvastatinSolute carrier organic anion transporter family member 2B1transporter
SimvastatinSolute carrier organic anion transporter family member 1B3transporter
SimvastatinHistone deacetylase 2target
SpironolactoneMineralocorticoid receptortarget
SpironolactoneCytochrome P450 2C8enzyme
SpironolactoneCanalicular multispecific organic anion transporter 1transporter
SpironolactoneP-glycoprotein 1transporter
SpironolactoneSolute carrier organic anion transporter family member 1A2transporter
SpironolactoneCytochrome P450 11B1, mitochondrialenzyme
SpironolactoneAndrogen receptortarget
SpironolactoneProgesterone receptortarget
SpironolactoneGlucocorticoid receptortarget
SpironolactoneCytochrome P450 11B2, mitochondrialtarget
SpironolactoneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
Spironolactone3-oxo-5-alpha-steroid 4-dehydrogenasetarget
SpironolactoneSex hormone-binding globulintarget
SpironolactoneVoltage-dependent calcium channeltarget
SpironolactoneNuclear receptor subfamily 1 group I member 2target
SpironolactoneBile salt export pumptransporter
SpironolactoneSerum albumincarrier
Spironolactonealpha1-acid glycoproteincarrier
Atorvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
AtorvastatinCytochrome P450 3A4enzyme
AtorvastatinDipeptidyl peptidase 4target
AtorvastatinCytochrome P450 2D6enzyme
AtorvastatinCytochrome P450 2C9enzyme
AtorvastatinCytochrome P450 2C19enzyme
AtorvastatinCytochrome P450 3A5enzyme
AtorvastatinCytochrome P450 3A7enzyme
AtorvastatinP-glycoprotein 1transporter
AtorvastatinSolute carrier organic anion transporter family member 1A2transporter
AtorvastatinSolute carrier organic anion transporter family member 1B1transporter
AtorvastatinMultidrug resistance-associated protein 4transporter
AtorvastatinMultidrug resistance-associated protein 5transporter
AtorvastatinMultidrug resistance-associated protein 1transporter
AtorvastatinCytochrome P450 2B6enzyme
AtorvastatinCytochrome P450 2C8enzyme
AtorvastatinAryl hydrocarbon receptortarget
AtorvastatinSolute carrier organic anion transporter family member 2B1transporter
AtorvastatinSolute carrier organic anion transporter family member 1B3transporter
AtorvastatinUDP-glucuronosyltransferase 1-1enzyme
AtorvastatinUDP-glucuronosyltransferase 1-3enzyme
AtorvastatinCanalicular multispecific organic anion transporter 1transporter
AtorvastatinBile salt export pumptransporter
AtorvastatinSerum albumincarrier
AtorvastatinHistone deacetylase 2target
AtorvastatinNuclear receptor subfamily 1 group I member 3target
Cerivastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
CerivastatinCytochrome P450 2C8enzyme
CerivastatinCytochrome P450 3A4enzyme
CerivastatinCytochrome P450 2D6enzyme
CerivastatinCytochrome P450 2C9enzyme
CerivastatinCytochrome P450 3A5enzyme
CerivastatinCytochrome P450 3A7enzyme
CerivastatinP-glycoprotein 1transporter
CerivastatinCanalicular multispecific organic anion transporter 1transporter
CerivastatinATP-binding cassette sub-family G member 2transporter
CerivastatinSolute carrier organic anion transporter family member 1B1transporter
CerivastatinCytochrome P450 2B6enzyme
CerivastatinUDP-glucuronosyltransferase 1-1enzyme
CerivastatinBile salt export pumptransporter
IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IsradipineCytochrome P450 3A4enzyme
IsradipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
IsradipineVoltage-dependent L-type calcium channel subunit beta-2target
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
IsradipineBile salt export pumptransporter
EzetimibeNiemann-Pick C1-like protein 1target
EzetimibeAminopeptidase Ntarget
EzetimibeSterol O-acyltransferase 1target
EzetimibeUDP-glucuronosyltransferase 1-1enzyme
EzetimibeUDP-glucuronosyltransferase 1-3enzyme
EzetimibeP-glycoprotein 1transporter
EzetimibeCanalicular multispecific organic anion transporter 1transporter
EzetimibeSolute carrier organic anion transporter family member 1B1transporter
EzetimibeUDP-glucuronosyltransferase 2B15enzyme
EzetimibeUDP-glucuronosyltransferase 2B7enzyme
EzetimibeCytochrome P450 3A4enzyme
EzetimibeCanalicular multispecific organic anion transporter 2transporter
EzetimibeATP-binding cassette sub-family G member 2transporter
EzetimibeCytochrome P450 2C8enzyme
EzetimibeBile salt export pumptransporter
DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DipyridamoleAdenosine deaminasetarget
DipyridamoleMultidrug resistance-associated protein 4transporter
DipyridamoleMultidrug resistance-associated protein 5transporter
DipyridamoleP-glycoprotein 1transporter
DipyridamoleCalcipressin-1target
DipyridamoleAlpha-1-acid glycoprotein 1target
DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DipyridamoleBile salt export pumptransporter
PitavastatinSolute carrier organic anion transporter family member 1B1transporter
PitavastatinSolute carrier organic anion transporter family member 1B3transporter
PitavastatinUDP-glucuronosyltransferase 2B7enzyme
PitavastatinUDP-glucuronosyltransferase 1-3enzyme
PitavastatinCytochrome P450 2C9enzyme
PitavastatinCytochrome P450 2C8enzyme
Pitavastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
PitavastatinSolute carrier organic anion transporter family member 2B1transporter
PitavastatinSodium/bile acid cotransportertransporter
PitavastatinATP-binding cassette sub-family G member 2transporter
PitavastatinP-glycoprotein 1transporter
PitavastatinCanalicular multispecific organic anion transporter 1transporter
PitavastatinSerum albumincarrier
PitavastatinAlpha-1-acid glycoprotein 1carrier
PitavastatinBile salt export pumptransporter
PitavastatinIntegrin alpha-Ltarget
FenofibratePeroxisome proliferator-activated receptor alphatarget
FenofibrateMatrix metalloproteinase-25target
FenofibrateCytochrome P450 2C8enzyme
FenofibrateCytochrome P450 2C9enzyme
FenofibrateNuclear receptor subfamily 1 group I member 2target
FenofibrateUDP-glucuronosyltransferase 1-9enzyme
FenofibrateBile salt export pumptransporter
FenofibrateSerum albumincarrier
FenofibrateCytochrome P450 2C19enzyme
FenofibrateCytochrome P450 2A6enzyme
FenofibrateLiver carboxylesterase 1enzyme
FenofibrateCarbonyl reductase [NADPH] 1enzyme
FenofibrateAldo-keto reductase family 1 member C1enzyme
FenofibrateAldo-keto reductase family 1 member C2enzyme
FenofibrateAldo-keto reductase family 1 member C3enzyme
FenofibrateAldose reductaseenzyme
AtazanavirHuman immunodeficiency virus type 1 proteasetarget
AtazanavirCytochrome P450 3A4enzyme
AtazanavirCytochrome P450 2C9enzyme
AtazanavirP-glycoprotein 1transporter
AtazanavirMultidrug resistance-associated protein 1transporter
AtazanavirSerum albumincarrier
AtazanavirUDP-glucuronosyltransferase 1-1enzyme
AtazanavirSolute carrier organic anion transporter family member 1B1transporter
AtazanavirSolute carrier organic anion transporter family member 1B3transporter
AtazanavirCytochrome P450 2C8enzyme
AtazanavirBile salt export pumptransporter
Atazanaviralpha1-acid glycoproteincarrier
AtazanavirCytochrome P450 1A2enzyme
AtazanavirSolute carrier organic anion transporter family member 2B1transporter
RepaglinideATP-binding cassette sub-family C member 8target
RepaglinideCytochrome P450 2C8enzyme
RepaglinidePeroxisome proliferator-activated receptor gammatarget
RepaglinideCytochrome P450 3A4enzyme
RepaglinideSerum albumincarrier
RepaglinideSolute carrier organic anion transporter family member 1B1transporter
RepaglinideBile salt export pumptransporter
SulfinpyrazoneMultidrug resistance-associated protein 1target
SulfinpyrazoneCanalicular multispecific organic anion transporter 1target
SulfinpyrazoneFatty acid-binding protein, intestinalcarrier
SulfinpyrazoneCytochrome P450 2C9enzyme
SulfinpyrazoneCanalicular multispecific organic anion transporter 2transporter
SulfinpyrazoneMultidrug resistance-associated protein 4transporter
SulfinpyrazoneMultidrug resistance-associated protein 5transporter
SulfinpyrazoneMultidrug resistance-associated protein 6transporter
SulfinpyrazoneMultidrug resistance-associated protein 1transporter
SulfinpyrazoneCanalicular multispecific organic anion transporter 1transporter
SulfinpyrazoneCytochrome P450 3A4enzyme
SulfinpyrazoneCytochrome P450 2B6enzyme
SulfinpyrazoneCytochrome P450 2C8enzyme
SulfinpyrazoneSolute carrier family 22 member 12target
SulfinpyrazoneNuclear receptor subfamily 1 group I member 2target
SulfinpyrazoneBile salt export pumptransporter
RanolazineCytochrome P450 3A4enzyme
RanolazineCytochrome P450 2D6enzyme
RanolazineBile salt export pumptransporter
RanolazineP-glycoprotein 1transporter
RanolazineSodium channel proteintarget
RanolazineInward rectifier potassium channeltarget
RanolazineVoltage gated L-type calcium channeltarget
RanolazineAlpha-1 adrenergic receptorstarget
RanolazineBeta-1 adrenergic receptortarget
RanolazineFatty acidtarget
RanolazineAlpha-1-acid glycoprotein 1carrier
RanolazineMultidrug and toxin extrusion protein 1transporter
RanolazineMultidrug and toxin extrusion protein 2transporter
RosiglitazonePeroxisome proliferator-activated receptor gammatarget
RosiglitazoneCytochrome P450 2C8enzyme
RosiglitazoneCytochrome P450 2C9enzyme
RosiglitazoneLong-chain-fatty-acid--CoA ligase 4target
RosiglitazoneSolute carrier organic anion transporter family member 1B1transporter
RosiglitazoneProstaglandin G/H synthase 1enzyme
RosiglitazoneCytochrome P450 1A2enzyme
RosiglitazoneCytochrome P450 2A6enzyme
RosiglitazoneCytochrome P450 2D6enzyme
RosiglitazoneSerum albumincarrier
RosiglitazonePeroxisome proliferator-activated receptor alphatarget
RosiglitazonePeroxisome proliferator-activated receptor deltatarget
RosiglitazoneRetinoic acid receptor RXR-alphatarget
RosiglitazoneRetinoic acid receptor RXR-betatarget
RosiglitazoneRetinoic acid receptor RXR-gammatarget
RosiglitazoneCytochrome P450 3A4enzyme
RosiglitazoneBile salt export pumptransporter
NelfinavirHIV-1 proteasetarget
NelfinavirCytochrome P450 2C19enzyme
NelfinavirCytochrome P450 3A4enzyme
NelfinavirCytochrome P450 2B6enzyme
NelfinavirCytochrome P450 3A5enzyme
NelfinavirCytochrome P450 3A7enzyme
NelfinavirP-glycoprotein 1transporter
NelfinavirSolute carrier family 22 member 1transporter
NelfinavirSolute carrier organic anion transporter family member 1A2transporter
NelfinavirATP-binding cassette sub-family G member 2transporter
NelfinavirSolute carrier organic anion transporter family member 1B1transporter
NelfinavirCytochrome P450 2D6enzyme
NelfinavirSerum albumincarrier
NelfinavirUDP-glucuronosyltransferase 1-1enzyme
NelfinavirSolute carrier organic anion transporter family member 1B3transporter
NelfinavirSolute carrier organic anion transporter family member 2B1transporter
NelfinavirBile salt export pumptransporter
NelfinavirCytochrome P450 2C9enzyme
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
IndinavirHuman immunodeficiency virus type 1 proteasetarget
IndinavirCytochrome P450 3A4enzyme
IndinavirCytochrome P450 3A5enzyme
IndinavirCytochrome P450 3A7enzyme
IndinavirP-glycoprotein 1transporter
IndinavirSolute carrier family 22 member 1transporter
IndinavirMultidrug resistance-associated protein 1transporter
IndinavirSolute carrier organic anion transporter family member 1A2transporter
IndinavirSolute carrier organic anion transporter family member 1B1transporter
IndinavirCanalicular multispecific organic anion transporter 1transporter
IndinavirCytochrome P450 2D6enzyme
IndinavirUDP-glucuronosyltransferase 1-1enzyme
IndinavirSolute carrier organic anion transporter family member 2B1transporter
IndinavirBile salt export pumptransporter
CefaclorPenicillin-binding protein 1Atarget
CefaclorSolute carrier family 15 member 1transporter
CefaclorSolute carrier family 15 member 2transporter
CefaclorPenicillin-binding protein 3target
CefaclorMyeloperoxidaseenzyme
CefaclorSolute carrier family 22 member 8transporter
CefaclorBile salt export pumptransporter
Prasterone sulfateCytochrome P450 19A1enzyme
Prasterone sulfateCytochrome P450 3A7enzyme
Prasterone sulfateProstaglandin G/H synthase 2enzyme
Prasterone sulfateSolute carrier family 22 member 8transporter
Prasterone sulfateSolute carrier organic anion transporter family member 1A2transporter
Prasterone sulfateSolute carrier organic anion transporter family member 1B1transporter
Prasterone sulfateSolute carrier organic anion transporter family member 1B3transporter
Prasterone sulfateSolute carrier organic anion transporter family member 2B1transporter
Prasterone sulfateSolute carrier family 10 member 6transporter
Prasterone sulfateBile salt export pumptransporter
AstemizoleHistamine H1 receptortarget
AstemizolePotassium voltage-gated channel subfamily H member 2target
AstemizoleCytochrome P450 3A4enzyme
AstemizoleCytochrome P450 3A5enzyme
AstemizoleCytochrome P450 3A7enzyme
AstemizoleP-glycoprotein 1transporter
AstemizoleCytochrome P450 2D6enzyme
AstemizoleCytochrome P450 2J2enzyme
AstemizolePotassium voltage-gated channel subfamily H member 1target
AstemizoleMicrotubule-associated protein tautarget
AstemizoleBile salt export pumptransporter
AmiodaroneBeta adrenergic receptortarget
AmiodaroneHERG human cardiac K+ channeltarget
AmiodaroneCytochrome P450 2C8enzyme
AmiodaroneCytochrome P450 2C9enzyme
AmiodaroneCytochrome P450 2D6enzyme
AmiodaroneVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmiodaroneVoltage gated L-type calcium channeltarget
AmiodaroneCytochrome P450 3A4enzyme
AmiodaroneCytochrome P450 1A2enzyme
AmiodaroneCytochrome P450 1A1enzyme
AmiodaroneP-glycoprotein 1transporter
AmiodaroneCytochrome P450 2C19enzyme
AmiodaroneCytochrome P450 2A6enzyme
AmiodaroneThyroid hormone receptortarget
AmiodaronePeroxisome proliferator-activated receptor gammatarget
AmiodaroneBile salt export pumptransporter
AmiodaroneSolute carrier family 22 member 2transporter
AmiodaroneCytochrome P450 2J2enzyme
AmiodaronePeroxisome proliferator-activated receptor alphatarget
AmiodaronePeroxisome proliferator-activated receptor gamma coactivator 1-betatarget
AmiodaroneSerum albumincarrier
TinidazoleCytochrome P450 3A4enzyme
TinidazoleDNAtarget
TinidazoleBile salt export pumptransporter
PilsicainideBile salt export pumptransporter
Nitrofurantoin30S ribosomal protein S10target
NitrofurantoinOxygen-insensitive NADPH nitroreductasetarget
NitrofurantoinProbable pyruvate-flavodoxin oxidoreductasetarget
NitrofurantoinATP-binding cassette sub-family G member 2transporter
NitrofurantoinNADPH--cytochrome P450 reductaseenzyme
NitrofurantoinBile salt export pumptransporter
NitrofurantoinP-glycoprotein 1transporter
NitrofurantoinCanalicular multispecific organic anion transporter 1transporter
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
FluvoxamineSodium-dependent serotonin transportertarget
FluvoxamineCytochrome P450 1A2enzyme
FluvoxamineCytochrome P450 2D6enzyme
FluvoxamineCytochrome P450 2C9enzyme
FluvoxamineCytochrome P450 2C19enzyme
FluvoxamineCytochrome P450 1A1enzyme
FluvoxamineCytochrome P450 3A4enzyme
FluvoxamineCytochrome P450 3A Subfamilyenzyme
FluvoxamineP-glycoprotein 1transporter
FluvoxamineCytochrome P450 2B6enzyme
FluvoxaminePotassium voltage-gated channel subfamily H member 2target
FluvoxamineBile salt export pumptransporter
OfloxacinDNA gyrase subunit Atarget
OfloxacinDNA topoisomerase 4 subunit Atarget
OfloxacinDNA topoisomerase 2-alphatarget
OfloxacinCytochrome P450 1A2enzyme
OfloxacinSolute carrier family 22 member 5transporter
OfloxacinMultidrug resistance-associated protein 1transporter
OfloxacinSolute carrier family 22 member 6transporter
OfloxacinCanalicular multispecific organic anion transporter 1transporter
OfloxacinSolute carrier family 22 member 4transporter
OfloxacinBile salt export pumptransporter
GlipizideCytochrome P450 2C9enzyme
GlipizidePeroxisome proliferator-activated receptor gammatarget
GlipizideATP-binding cassette sub-family C member 8target
GlipizideUDP-glucuronosyltransferase 1-1enzyme
GlipizideBile salt export pumptransporter
GlipizideSerum albumincarrier
AtenololBeta-1 adrenergic receptortarget
AtenololBeta-2 adrenergic receptortarget
AtenololCytochrome P450 2D6enzyme
AtenololBile salt export pumptransporter
AtenololSerum albumincarrier
EfavirenzCytochrome P450 2B6enzyme
EfavirenzCytochrome P450 3A4enzyme
EfavirenzCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2C9enzyme
EfavirenzCytochrome P450 1A2enzyme
EfavirenzCytochrome P450 2D6enzyme
EfavirenzReverse transcriptase/RNaseHtarget
EfavirenzCytochrome P450 2C8enzyme
EfavirenzSerum albumincarrier
EfavirenzCytochrome P450 3A5enzyme
EfavirenzCytochrome P450 3A7enzyme
EfavirenzUDP-glucuronosyltransferase 1-1enzyme
EfavirenzBile salt export pumptransporter
EfavirenzSolute carrier family 22 member 1transporter
TerfenadineHistamine H1 receptortarget
TerfenadinePotassium voltage-gated channel subfamily H member 2target
TerfenadineCytochrome P450 3A4enzyme
TerfenadineCytochrome P450 2D6enzyme
TerfenadineMuscarinic acetylcholine receptor M3target
TerfenadineCytochrome P450 3A5enzyme
TerfenadineCytochrome P450 3A7enzyme
TerfenadineP-glycoprotein 1transporter
TerfenadineCytochrome P450 2C8enzyme
TerfenadineCytochrome P450 2J2enzyme
TerfenadineMuscarinic acetylcholine receptor M1target
TerfenadineMuscarinic acetylcholine receptor M5target
TerfenadineMuscarinic acetylcholine receptor M4target
TerfenadineMuscarinic acetylcholine receptor M2target
TerfenadineBile salt export pumptransporter
Clarithromycin50S ribosomal protein L10target
ClarithromycinCytochrome P450 3A4enzyme
ClarithromycinCytochrome P450 3A5enzyme
ClarithromycinP-glycoprotein 1transporter
ClarithromycinSolute carrier family 22 member 7transporter
ClarithromycinPotassium voltage-gated channel subfamily H member 2target
ClarithromycinSolute carrier organic anion transporter family member 1B1target
ClarithromycinSolute carrier organic anion transporter family member 1B3target
ClarithromycinBile salt export pumptransporter
ClarithromycinSolute carrier organic anion transporter family member 1B1transporter
ClarithromycinSolute carrier organic anion transporter family member 1B3transporter
Glycyrrhizic acidCorticosteroid 11-beta-dehydrogenase isozyme 1target
Glycyrrhizic acidAldo-keto reductase family 1 member C4carrier
Glycyrrhizic acidAldo-keto reductase family 1 member C3carrier
Glycyrrhizic acidAldo-keto reductase family 1 member C2carrier
Glycyrrhizic acidTumor necrosis factortarget
Glycyrrhizic acidCaspase-3target
Glycyrrhizic acidNuclear factor NF-kappa-Btarget
Glycyrrhizic acidLipoprotein lipasetarget
Glycyrrhizic acidSerum albumincarrier
Glycyrrhizic acidBile salt export pumptransporter
AtropineMuscarinic acetylcholine receptor M2target
AtropineMuscarinic acetylcholine receptor M1target
AtropineMuscarinic acetylcholine receptor M4target
AtropineMuscarinic acetylcholine receptor M5target
AtropineMuscarinic acetylcholine receptor M3target
AtropineGlycine receptor subunit alpha-1target
AtropineNeuronal acetylcholine receptor subunit alpha-4target
AtropineNeuronal acetylcholine receptor subunit beta-2target
AtropineBile salt export pumptransporter
FlucloxacillinPenicillin-binding protein 1Atarget
FlucloxacillinCytochrome P450 3A4enzyme
FlucloxacillinBile salt export pumptransporter
NitrendipineCytochrome P450 3A4enzyme
NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
NitrendipineCytochrome P450 3A5enzyme
NitrendipineCytochrome P450 3A7enzyme
NitrendipineP-glycoprotein 1transporter
NitrendipineBile salt export pumptransporter
Erythromycin23S ribosomal RNAtarget
ErythromycinCytochrome P450 3A4enzyme
ErythromycinCytochrome P450 3A7enzyme
ErythromycinP-glycoprotein 1transporter
ErythromycinSolute carrier organic anion transporter family member 1B1transporter
ErythromycinMotilin receptortarget
ErythromycinPotassium voltage-gated channel subfamily H member 2target
ErythromycinCytochrome P450 3A5enzyme
ErythromycinSolute carrier organic anion transporter family member 1B3transporter
ErythromycinBile salt export pumptransporter
ErythromycinCanalicular multispecific organic anion transporter 1transporter
ErythromycinSolute carrier organic anion transporter family member 1A2transporter
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
NifedipineCytochrome P450 3A4enzyme
NifedipineCytochrome P450 2E1enzyme
NifedipineCytochrome P450 2D6enzyme
NifedipineCalmodulintarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
NifedipinePotassium voltage-gated channel subfamily D member 3target
NifedipineVoltage-dependent T-type calcium channeltarget
NifedipineCytochrome P450 1A2enzyme
NifedipineCytochrome P450 2A6enzyme
NifedipineCytochrome P450 2C8enzyme
NifedipineCanalicular multispecific organic anion transporter 2transporter
NifedipineP-glycoprotein 1transporter
NifedipineCanalicular multispecific organic anion transporter 1transporter
NifedipineCytochrome P450 1A1enzyme
NifedipineCytochrome P450 2B6enzyme
NifedipineNuclear receptor subfamily 1 group I member 2target
NifedipineSolute carrier organic anion transporter family member 1B1transporter
NifedipineBile salt export pumptransporter
NifedipineCytochrome P450 2C9enzyme
NifedipineSerum albumincarrier
Nifedipinealpha1-acid glycoproteincarrier
NifedipineCytochrome P450 3A5enzyme
SulfamethoxazoleCytochrome P450 2C9enzyme
SulfamethoxazoleSerum albumincarrier
SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
SulfamethoxazoleDihydropteroate synthasetarget
SulfamethoxazoleCytochrome P450 3A4enzyme
SulfamethoxazoleBile salt export pumptransporter
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenSerum albumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenP-glycoprotein 1transporter
NaproxenUDP-glucuronosyltransferase 1-3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1-7enzyme
NaproxenUDP-glucuronosyltransferase 1-8enzyme
NaproxenUDP-glucuronosyltransferase 1-9enzyme
NaproxenUDP-glucuronosyltransferase 1-10enzyme
NaproxenSolute carrier family 22 member 8transporter
CyclosporineCalcium signal-modulating cyclophilin ligandtarget
CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
CyclosporineCalcineurin subunit B type 2target
CyclosporineCytochrome P450 3A5enzyme
CyclosporineCytochrome P450 3A4enzyme
CyclosporineP-glycoprotein 1transporter
CyclosporineBile salt export pumptransporter
CyclosporineIleal sodium/bile acid cotransportertransporter
CyclosporineSodium/bile acid cotransportertransporter
CyclosporineSolute carrier family 22 member 6transporter
CyclosporineMultidrug resistance-associated protein 7transporter
CyclosporineCanalicular multispecific organic anion transporter 1transporter
CyclosporineATP-binding cassette sub-family G member 2transporter
CyclosporineSolute carrier organic anion transporter family member 1B1transporter
CyclosporineCytochrome P450 2C19enzyme
CyclosporineCytochrome P450 2D6enzyme
CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
CyclosporineSolute carrier organic anion transporter family member 1B3transporter
Belantamab mafodotinSolute carrier organic anion transporter family member 1B1transporter
Belantamab mafodotinSolute carrier organic anion transporter family member 1B3transporter
Belantamab mafodotinMultidrug resistance-associated protein 1transporter
Belantamab mafodotinCanalicular multispecific organic anion transporter 1transporter
Belantamab mafodotinCanalicular multispecific organic anion transporter 2transporter
Belantamab mafodotinBile salt export pumptransporter
Belantamab mafodotinP-glycoprotein 1transporter
Belantamab mafodotinTumor necrosis factor receptor superfamily member 17target