Cytochrome P-450 CYP2B6 Inhibitors (strength unknown)

Accession Number

DBCAT004517

Description

Not Available

Drugs

Drug	Drug Description
Nelfinavir	A viral protease inhibitor used in the treatment of HIV infection.
Selegiline	A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
Amlodipine	A calcium channel blocker used to treat hypertension and angina.
Desipramine	A tricyclic antidepressant used in the treatment of depression.
Doxorubicin	A medication used to treat various cancers, including AIDS-associated Kaposi's Sarcoma and metastatic cancers.
Phencyclidine	A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like...
Azelastine	A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
Colchicine	An alkaloid used to treat gout and Familial Mediterranean Fever as well as prevent major cardiovascular events.
Ethanol	For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical...
Miconazole	An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
Quinidine	A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
Roxithromycin	An antibiotic used to treat a variety of susceptible bacterial infections.
Sulfaphenazole	For the treatment bacterial infections.
Nitric Oxide	A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
Cisplatin	A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.
Regorafenib	A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
Enzalutamide	A second-generation androgen receptor inhibitor used to treat castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer.
Crizotinib	A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
Enasidenib	An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
Lenvatinib	A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
Rifamycin	An antibacterial used to treat traveler's diarrhea.
Triclabendazole	An anthelmintic drug used to treat fascioliasis.
Paroxetine	A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
Pexidartinib	An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
Fluvoxamine	A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
Modafinil	A stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder.
Curcumin sulfate	No approved therapeutic indications.
Abemaciclib	A medication used to treat HR+ HER2- advanced or metastatic breast cancer.
Elexacaftor	A small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation.
Cenobamate	A small molecule drug indicated to treat partial onset seizures in adults.
Sertraline	A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.
Lopinavir	An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
Ritonavir	An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
Methylene blue	An oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia.
Abametapir	A pediculicide metalloproteinase used topically in the treatment of head lice infection.
Dabrafenib	A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Opicapone	A catechol-O-methyltransferase inhibitor used as an adjunct treatment for Parkinson's Disease in adults currently receiving levodopa and a dopa decarboxylase inhibitor.
Menadione	The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification.
Duloxetine	A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.
Brincidofovir	An oral lipid prodrug of cidofovir used in the treatment of human smallpox disease.
Fexinidazole	An orally bioavailable 2-substituted 5-nitroimidazole used to treat early- and late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense.
Levoketoconazole	One of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing's syndrome.
Dronabinol	A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
Cannabidiol	An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer.
Cannabinol	Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Medical Cannabis	The use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical...
Viloxazine	A selective norepinephrine reuptake inhibitor indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults in children.
Stiripentol	An antiepileptic agent used in combination with other anticonvulsants to treat seizures associated with Dravet syndrome.
Resveratrol	Being investigated for the treatment of Herpes labialis infections (cold sores).
Pirtobrutinib	A kinase inhibitor used to treat relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy.
Tezacaftor	A medication used to treat homozygous or heterozygous F508del mutation cystic fibrosis.
Encorafenib	A kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations.
Mavorixafor	A CXC chemokine receptor 4 antagonist used to treat WHIM syndrome.

Drugs & Drug Targets

Drug	Target	Type
Nelfinavir	HIV-1 protease	target
Nelfinavir	Cytochrome P450 2C19	enzyme
Nelfinavir	Cytochrome P450 3A4	enzyme
Nelfinavir	Cytochrome P450 2B6	enzyme
Nelfinavir	Cytochrome P450 3A5	enzyme
Nelfinavir	Cytochrome P450 3A7	enzyme
Nelfinavir	P-glycoprotein 1	transporter
Nelfinavir	Solute carrier family 22 member 1	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1A2	transporter
Nelfinavir	ATP-binding cassette sub-family G member 2	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1B1	transporter
Nelfinavir	Cytochrome P450 2D6	enzyme
Nelfinavir	Serum albumin	carrier
Nelfinavir	UDP-glucuronosyltransferase 1-1	enzyme
Nelfinavir	Solute carrier organic anion transporter family member 1B3	transporter
Nelfinavir	Solute carrier organic anion transporter family member 2B1	transporter
Nelfinavir	Bile salt export pump	transporter
Nelfinavir	Cytochrome P450 2C9	enzyme
Nelfinavir	Alpha-1-acid glycoprotein 1	carrier
Selegiline	Amine oxidase [flavin-containing] B	target
Selegiline	Cytochrome P450 2B6	enzyme
Selegiline	Amine oxidase [flavin-containing] A	target
Selegiline	Cytochrome P450 2A6	enzyme
Selegiline	Cytochrome P450 3A4	enzyme
Selegiline	P-glycoprotein 1	transporter
Selegiline	Cytochrome P450 1A2	enzyme
Selegiline	Cytochrome P450 2C19	enzyme
Selegiline	Cytochrome P450 2C8	enzyme
Selegiline	Cytochrome P450 2C9	enzyme
Selegiline	Cytochrome P450 2D6	enzyme
Selegiline	Neurokinin 1 receptor	target
Amlodipine	Carbonic anhydrase 1	target
Amlodipine	Cytochrome P450 3A4	enzyme
Amlodipine	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Amlodipine	Cytochrome P450 1A1	enzyme
Amlodipine	Cytochrome P450 2B6	enzyme
Amlodipine	Voltage-dependent N-type calcium channel subunit alpha-1B	target
Amlodipine	Voltage-dependent L-type calcium channel subunit beta-1	target
Amlodipine	Voltage-dependent calcium channel subunit alpha-2/delta-3	target
Amlodipine	Cytochrome P450 3A5	enzyme
Amlodipine	P-glycoprotein 1	transporter
Amlodipine	Cytochrome P450 2C8	enzyme
Amlodipine	Cytochrome P450 2D6	enzyme
Amlodipine	Sphingomyelin phosphodiesterase	target
Amlodipine	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Amlodipine	Voltage-dependent N-type calcium channel	target
Amlodipine	Cytochrome P450 2C19	enzyme
Amlodipine	Cytochrome P450 2C9	enzyme
Amlodipine	Voltage-dependent calcium channel subunit alpha-2/delta-1	target
Desipramine	Muscarinic acetylcholine receptor M1	target
Desipramine	Sodium-dependent noradrenaline transporter	target
Desipramine	Beta-2 adrenergic receptor	target
Desipramine	Muscarinic acetylcholine receptor M2	target
Desipramine	Sodium-dependent serotonin transporter	target
Desipramine	Histamine H1 receptor	target
Desipramine	Beta-1 adrenergic receptor	target
Desipramine	Cytochrome P450 2D6	enzyme
Desipramine	Muscarinic acetylcholine receptor M3	target
Desipramine	Muscarinic acetylcholine receptor M4	target
Desipramine	Muscarinic acetylcholine receptor M5	target
Desipramine	Alpha-1 adrenergic receptors	target
Desipramine	5-hydroxytryptamine receptor 2A	target
Desipramine	Alpha-1-acid glycoprotein 1	carrier
Desipramine	Cytochrome P450 2B6	enzyme
Desipramine	Cytochrome P450 3A4	enzyme
Desipramine	Solute carrier family 22 member 2	transporter
Desipramine	Solute carrier family 22 member 1	transporter
Desipramine	Solute carrier family 22 member 3	transporter
Desipramine	Solute carrier family 22 member 5	transporter
Desipramine	P-glycoprotein 1	transporter
Desipramine	Solute carrier family 22 member 4	transporter
Desipramine	Cytochrome P450 1A2	enzyme
Desipramine	Cytochrome P450 2E1	enzyme
Desipramine	Sphingomyelin phosphodiesterase	target
Desipramine	5-hydroxytryptamine receptor 1A	target
Desipramine	5-hydroxytryptamine receptor 2C	target
Desipramine	Dopamine D2 receptor	target
Desipramine	Alpha-2 adrenergic receptors	target
Doxorubicin	DNA topoisomerase 2-alpha	target
Doxorubicin	DNA	target
Doxorubicin	Cytochrome P450 3A4	enzyme
Doxorubicin	Cytochrome P450 2D6	enzyme
Doxorubicin	Cytochrome P450 2B6	enzyme
Doxorubicin	P-glycoprotein 1	transporter
Doxorubicin	Canalicular multispecific organic anion transporter 2	transporter
Doxorubicin	Multidrug resistance-associated protein 6	transporter
Doxorubicin	Multidrug resistance-associated protein 1	transporter
Doxorubicin	Multidrug resistance-associated protein 7	transporter
Doxorubicin	ATP-binding cassette sub-family G member 2	transporter
Doxorubicin	Bile salt export pump	transporter
Doxorubicin	Solute carrier family 22 member 16	transporter
Doxorubicin	ATP-binding cassette sub-family B member 8, mitochondrial	transporter
Doxorubicin	Cytochrome P450 1B1	enzyme
Doxorubicin	Carbonyl reductase [NADPH] 1	enzyme
Doxorubicin	Carbonyl reductase [NADPH] 3	enzyme
Doxorubicin	Alcohol dehydrogenase [NADP(+)]	enzyme
Doxorubicin	Aldo-keto reductase family 1 member C3	enzyme
Doxorubicin	NAD(P)H dehydrogenase [quinone] 1	enzyme
Doxorubicin	Xanthine dehydrogenase/oxidase	enzyme
Doxorubicin	Nitric oxide synthase, endothelial	enzyme
Doxorubicin	Nitric oxide synthase, inducible	enzyme
Doxorubicin	Nitric oxide synthase, brain	enzyme
Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	enzyme
Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	enzyme
Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	enzyme
Doxorubicin	NADPH--cytochrome P450 reductase	enzyme
Doxorubicin	RalA-binding protein 1	transporter
Doxorubicin	Canalicular multispecific organic anion transporter 1	transporter
Doxorubicin	Serum albumin	carrier
Doxorubicin	Nucleolar and coiled-body phosphoprotein 1	target
Doxorubicin	DNA topoisomerase 1	target
Doxorubicin	DNA topoisomerase 2-beta	target
Doxorubicin	Aldose reductase	enzyme
Doxorubicin	Aldo-keto reductase family 1 member B10	enzyme
Doxorubicin	Aldo-keto reductase family 1 member C4	enzyme
Doxorubicin	Telomerase reverse transcriptase	target
Phencyclidine	Glutamate receptor ionotropic, NMDA 3A	target
Phencyclidine	Sigma non-opioid intracellular receptor 1	target
Phencyclidine	Cytochrome P450 2B6	enzyme
Phencyclidine	Glutamate receptor ionotropic, NMDA 1	target
Phencyclidine	Glutamate receptor ionotropic, NMDA 2B	target
Phencyclidine	Glutamate receptor ionotropic, NMDA 2A	target
Azelastine	Histamine H1 receptor	target
Azelastine	Cytochrome P450 1A2	enzyme
Azelastine	Cytochrome P450 2D6	enzyme
Azelastine	Cytochrome P450 3A4	enzyme
Azelastine	Cytochrome P450 2C19	enzyme
Azelastine	Cytochrome P450 1A1	enzyme
Azelastine	Cytochrome P450 3A5	enzyme
Azelastine	Cytochrome P450 2C9	enzyme
Azelastine	Cytochrome P450 2C8	enzyme
Azelastine	P-glycoprotein 1	transporter
Azelastine	Cytochrome P450 2A6	enzyme
Azelastine	Cytochrome P450 2E1	enzyme
Azelastine	Histamine H2 receptor	target
Azelastine	Phospholipase A2	target
Azelastine	Leukotriene C4 synthase	target
Azelastine	Cytochrome P450 2B6	enzyme
Colchicine	Tubulin beta chain	target
Colchicine	Cytochrome P450 3A4	enzyme
Colchicine	P-glycoprotein 1	transporter
Colchicine	Cytochrome P450 2B6	enzyme
Colchicine	Cytochrome P450 2C8	enzyme
Colchicine	Cytochrome P450 2E1	enzyme
Colchicine	Serum albumin	carrier
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-1	target
Ethanol	Glutamate receptor ionotropic, NMDA 3A	target
Ethanol	Glycine receptor subunit alpha-1	target
Ethanol	Glycine receptor subunit alpha-2	target
Ethanol	Cytochrome P450 2E1	enzyme
Ethanol	Cytochrome P450 1A1	enzyme
Ethanol	Cytochrome P450 1A2	enzyme
Ethanol	Cytochrome P450 2B6	enzyme
Ethanol	Cytochrome P450 2C19	enzyme
Ethanol	Cytochrome P450 2C9	enzyme
Ethanol	Cytochrome P450 3A4	enzyme
Ethanol	Cytochrome P450 4A11	enzyme
Ethanol	Alcohol dehydrogenase 1A	enzyme
Ethanol	Alcohol dehydrogenase 1B	enzyme
Ethanol	Alcohol dehydrogenase 1C	enzyme
Ethanol	Alcohol dehydrogenase class-3	enzyme
Ethanol	Voltage-dependent L-type calcium channel subunit beta-1	target
Ethanol	5-hydroxytryptamine receptor 3A	target
Ethanol	Alcohol dehydrogenase 4	enzyme
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-2	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-10	target
Ethanol	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-5	target
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-4	target
Ethanol	Alcohol dehydrogenase class 4 mu/sigma chain	enzyme
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-3	target
Ethanol	Glutamate receptor 1	target
Ethanol	Voltage-dependent calcium channel gamma-1 subunit	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-2	target
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-6	target
Ethanol	Glutamate receptor 2	target
Ethanol	Glutamate receptor 4	target
Ethanol	Glutamate receptor 3	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-4	target
Ethanol	Neuronal acetylcholine receptor subunit beta-2	target
Ethanol	G protein-activated inward rectifier potassium channel 1	target
Ethanol	G protein-activated inward rectifier potassium channel 2	target
Ethanol	Vascular cell adhesion protein 1	target
Ethanol	Equilibrative nucleoside transporter 1	target
Ethanol	G protein-activated inward rectifier potassium channel 4	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-7	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-9	target
Ethanol	Gamma-aminobutyric acid receptor subunit beta-1	target
Ethanol	Gamma-aminobutyric acid receptor subunit beta-3	target
Ethanol	Gamma-aminobutyric acid receptor subunit beta-2	target
Ethanol	Voltage-dependent L-type calcium channel subunit alpha-1S	target
Ethanol	Voltage-dependent L-type calcium channel subunit alpha-1D	target
Ethanol	Alcohol dehydrogenase 6	enzyme
Ethanol	Neuronal acetylcholine receptor subunit beta-4	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-3	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-5	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-6	target
Ethanol	Neuronal acetylcholine receptor subunit beta-3	target
Ethanol	Gamma-aminobutyric acid receptor subunit gamma-1	target
Ethanol	Gamma-aminobutyric acid receptor subunit gamma-3	target
Ethanol	Gamma-aminobutyric acid receptor subunit epsilon	target
Ethanol	Gamma-aminobutyric acid receptor subunit pi	target
Ethanol	Gamma-aminobutyric acid receptor subunit theta	target
Ethanol	Gamma-aminobutyric acid receptor subunit delta	target
Ethanol	Alcohol dehydrogenase [NADP(+)]	enzyme
Ethanol	Equilibrative nucleoside transporter 2	target
Ethanol	5-hydroxytryptamine receptor 3E	target
Ethanol	5-hydroxytryptamine receptor 3B	target
Ethanol	5-hydroxytryptamine receptor 3D	target
Ethanol	5-hydroxytryptamine receptor 3C	target
Ethanol	Voltage-dependent calcium channel gamma-2 subunit	target
Ethanol	G protein-activated inward rectifier potassium channel 3	target
Ethanol	Neural cell adhesion molecule L1	target
Ethanol	Acetylcholinesterase	target
Ethanol	Alcohol dehydrogenase class 4 mu/sigma chain	target
Miconazole	Cytochrome P450 2C9	enzyme
Miconazole	Cytochrome P450 2D6	enzyme
Miconazole	Cytochrome P450 3A4	enzyme
Miconazole	P-glycoprotein 1	transporter
Miconazole	Cytochrome P450 51	target
Miconazole	Nitric oxide synthase, endothelial	target
Miconazole	Nitric oxide synthase, inducible	target
Miconazole	Cytochrome P450 11B1, mitochondrial	enzyme
Miconazole	Cytochrome P450 2A6	enzyme
Miconazole	Cytochrome P450 2B6	enzyme
Miconazole	Cytochrome P450 2C19	enzyme
Miconazole	Cytochrome P450 2E1	enzyme
Miconazole	Nuclear receptor subfamily 1 group I member 2	target
Miconazole	Lanosterol 14-alpha demethylase	enzyme
Miconazole	Cytochrome P450 19A1	enzyme
Miconazole	Calcium-activated potassium channel	target
Miconazole	Voltage-gated Potassium Channels	target
Miconazole	Inward rectifier potassium channel	target
Miconazole	Voltage gated L-type calcium channel	target
Miconazole	Serum albumin	carrier
Miconazole	Cytochrome P450 2C8	enzyme
Quinidine	Sodium channel protein type 5 subunit alpha	target
Quinidine	Alpha-1-acid glycoprotein 1	carrier
Quinidine	Potassium voltage-gated channel subfamily H member 2	target
Quinidine	Potassium channel subfamily K member 1	target
Quinidine	Potassium channel subfamily K member 6	target
Quinidine	Cytochrome P450 1A2	enzyme
Quinidine	Cytochrome P450 2E1	enzyme
Quinidine	Cytochrome P450 1A1	enzyme
Quinidine	Cytochrome P450 2D6	enzyme
Quinidine	Cytochrome P450 3A4	enzyme
Quinidine	Cytochrome P450 3A7	enzyme
Quinidine	Solute carrier family 22 member 2	transporter
Quinidine	Solute carrier family 22 member 1	transporter
Quinidine	Solute carrier family 22 member 5	transporter
Quinidine	P-glycoprotein 1	transporter
Quinidine	Solute carrier organic anion transporter family member 1A2	transporter
Quinidine	Solute carrier family 22 member 8	transporter
Quinidine	Canalicular multispecific organic anion transporter 1	transporter
Quinidine	Solute carrier family 22 member 4	transporter
Quinidine	Solute carrier organic anion transporter family member 1B1	transporter
Quinidine	Cytochrome P450 2B6	enzyme
Quinidine	Cytochrome P450 2C9	enzyme
Quinidine	Alpha-1A adrenergic receptor	target
Quinidine	Alpha-1B adrenergic receptor	target
Quinidine	Alpha-1D adrenergic receptor	target
Quinidine	Bile salt export pump	transporter
Quinidine	Cytochrome P450 2C8	enzyme
Quinidine	Serum albumin	carrier
Roxithromycin	50S ribosomal protein L10	target
Roxithromycin	P-glycoprotein 1	target
Roxithromycin	Cytochrome P450 3A4	enzyme
Roxithromycin	Cytochrome P450 2B6	enzyme
Sulfaphenazole	Cytochrome P450 2C9	enzyme
Sulfaphenazole	Cytochrome P450 2B6	enzyme
Sulfaphenazole	Cytochrome P450 2C8	enzyme
Sulfaphenazole	Cytochrome P450 2D6	enzyme
Sulfaphenazole	Dihydropteroate synthase	target
Sulfaphenazole	Cytochrome P450 2C9	target
Nitric Oxide	Guanylate cyclase soluble subunit alpha-2	target
Nitric Oxide	Aldehyde dehydrogenase, mitochondrial	enzyme
Nitric Oxide	Cytochrome P450 1A2	enzyme
Nitric Oxide	Cytochrome P450 2B6	enzyme
Nitric Oxide	Cytochrome P450 3A4	enzyme
Nitric Oxide	Metallothionein-1A	target
Nitric Oxide	Indoleamine 2,3-dioxygenase 1	target
Nitric Oxide	Nitric oxide synthase, endothelial	target
Nitric Oxide	Guanylate cyclase soluble subunit alpha-1	target
Nitric Oxide	Guanylate cyclase soluble subunit beta-1	target
Cisplatin	DNA	target
Cisplatin	Canalicular multispecific organic anion transporter 2	transporter
Cisplatin	Multidrug resistance-associated protein 5	transporter
Cisplatin	Canalicular multispecific organic anion transporter 1	transporter
Cisplatin	Solute carrier family 22 member 2	transporter
Cisplatin	High affinity copper uptake protein 1	transporter
Cisplatin	Probable low affinity copper uptake protein 2	transporter
Cisplatin	Multidrug resistance-associated protein 6	transporter
Cisplatin	Copper-transporting ATPase 2	transporter
Cisplatin	Copper-transporting ATPase 1	transporter
Cisplatin	Prostaglandin G/H synthase 2	enzyme
Cisplatin	Myeloperoxidase	enzyme
Cisplatin	Xanthine dehydrogenase/oxidase	enzyme
Cisplatin	Arylamine N-acetyltransferase	enzyme
Cisplatin	Cytochrome P450 2C9	enzyme
Cisplatin	Cytochrome P450 2B6	enzyme
Cisplatin	Cholinesterase	enzyme
Cisplatin	Cytochrome P450 4A11	enzyme
Cisplatin	ATP-binding cassette sub-family G member 2	transporter
Cisplatin	Glutathione S-transferase theta-1	enzyme
Cisplatin	Metallothionein-1A	enzyme
Cisplatin	Metallothionein-2	enzyme
Cisplatin	Superoxide dismutase [Cu-Zn]	enzyme
Cisplatin	Glutathione S-transferase P	enzyme
Cisplatin	NAD(P)H dehydrogenase [quinone] 1	enzyme
Cisplatin	Glutathione S-transferase Mu 1	enzyme
Cisplatin	DNA-3-methyladenine glycosylase	target
Cisplatin	Alpha-2-macroglobulin	target
Cisplatin	Serum albumin	carrier
Cisplatin	Serotransferrin	target
Cisplatin	Copper transport protein ATOX1	target
Regorafenib	Cytochrome P450 3A4	enzyme
Regorafenib	UDP-glucuronosyltransferase 1-9	enzyme
Regorafenib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Regorafenib	Vascular endothelial growth factor receptor 1	target
Regorafenib	Vascular endothelial growth factor receptor 2	target
Regorafenib	Vascular endothelial growth factor receptor 3	target
Regorafenib	Mast/stem cell growth factor receptor Kit	target
Regorafenib	Platelet-derived growth factor receptor alpha	target
Regorafenib	Platelet-derived growth factor receptor beta	target
Regorafenib	Fibroblast growth factor receptor 1	target
Regorafenib	Fibroblast growth factor receptor 2	target
Regorafenib	Angiopoietin-1 receptor	target
Regorafenib	Discoidin domain-containing receptor 2	target
Regorafenib	High affinity nerve growth factor receptor	target
Regorafenib	Ephrin type-A receptor 2	target
Regorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Regorafenib	Serine/threonine-protein kinase B-raf	target
Regorafenib	Cytochrome P450 2C8	enzyme
Regorafenib	Cytochrome P450 2C9	enzyme
Regorafenib	Cytochrome P450 2B6	enzyme
Regorafenib	Mitogen-activated protein kinase 11	target
Regorafenib	Tyrosine-protein kinase FRK	target
Regorafenib	Tyrosine-protein kinase ABL1	target
Regorafenib	P-glycoprotein 1	transporter
Regorafenib	ATP-binding cassette sub-family G member 2	transporter
Regorafenib	UDP-glucuronosyltransferase 1-1	enzyme
Regorafenib	Cytochrome P450 2C19	enzyme
Enzalutamide	Serum albumin	carrier
Enzalutamide	Cytochrome P450 2C8	enzyme
Enzalutamide	Cytochrome P450 3A4	enzyme
Enzalutamide	Androgen receptor	target
Enzalutamide	Cytochrome P450 2C9	enzyme
Enzalutamide	Cytochrome P450 2C19	enzyme
Enzalutamide	Cytochrome P450 2B6	enzyme
Enzalutamide	Cytochrome P450 3A5	enzyme
Enzalutamide	P-glycoprotein 1	transporter
Crizotinib	Cytochrome P450 3A4	enzyme
Crizotinib	Cytochrome P450 3A5	enzyme
Crizotinib	P-glycoprotein 1	transporter
Crizotinib	ALK tyrosine kinase receptor	target
Crizotinib	Hepatocyte growth factor receptor	target
Crizotinib	Cytochrome P450 2B6	enzyme
Crizotinib	Cytochrome P450 3A Subfamily	enzyme
Crizotinib	Serum albumin	carrier
Crizotinib	alpha1-acid glycoprotein	carrier
Crizotinib	Proto-oncogene tyrosine-protein kinase ROS	target
Crizotinib	Macrophage-stimulating protein receptor	target
Enasidenib	Cytochrome P450 1A2	enzyme
Enasidenib	Cytochrome P450 2B6	enzyme
Enasidenib	Isocitrate dehydrogenase [NADP], mitochondrial	target
Enasidenib	Cytochrome P450 2C8	enzyme
Enasidenib	Cytochrome P450 2C9	enzyme
Enasidenib	Cytochrome P450 2C19	enzyme
Enasidenib	Cytochrome P450 2D6	enzyme
Enasidenib	Cytochrome P450 3A4	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-1	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-3	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-4	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-9	enzyme
Enasidenib	UDP-glucuronosyltransferase 2B7	enzyme
Enasidenib	UDP-glucuronosyltransferase 2B15	enzyme
Enasidenib	P-glycoprotein 1	transporter
Enasidenib	ATP-binding cassette sub-family G member 2	transporter
Enasidenib	Solute carrier family 22 member 6	transporter
Enasidenib	Solute carrier organic anion transporter family member 1B1	transporter
Enasidenib	Solute carrier family 22 member 2	transporter
Enasidenib	Solute carrier organic anion transporter family member 1B3	transporter
Enasidenib	Solute carrier family 22 member 8	transporter
Enasidenib	Serum albumin	carrier
Enasidenib	Isocitrate dehydrogenase [NADP] cytoplasmic	target
Enasidenib	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	target
Enasidenib	Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial	target
Enasidenib	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	target
Lenvatinib	Vascular endothelial growth factor receptor 1	target
Lenvatinib	Vascular endothelial growth factor receptor 2	target
Lenvatinib	Vascular endothelial growth factor receptor 3	target
Lenvatinib	Fibroblast growth factor receptor 1	target
Lenvatinib	Fibroblast growth factor receptor 2	target
Lenvatinib	Fibroblast growth factor receptor 3	target
Lenvatinib	Fibroblast growth factor receptor 4	target
Lenvatinib	Platelet-derived growth factor receptor alpha	target
Lenvatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Lenvatinib	Mast/stem cell growth factor receptor Kit	target
Lenvatinib	P-glycoprotein 1	transporter
Lenvatinib	ATP-binding cassette sub-family G member 2	transporter
Lenvatinib	Cytochrome P450 3A4	enzyme
Lenvatinib	Aldehyde oxidase	enzyme
Lenvatinib	Cytochrome P450 2C8	enzyme
Lenvatinib	Cytochrome P450 2C9	enzyme
Lenvatinib	Cytochrome P450 1A2	enzyme
Lenvatinib	Cytochrome P450 2B6	enzyme
Lenvatinib	Cytochrome P450 2C19	enzyme
Lenvatinib	Solute carrier family 22 member 6	transporter
Lenvatinib	Solute carrier family 22 member 8	transporter
Lenvatinib	Solute carrier family 22 member 2	transporter
Lenvatinib	Solute carrier organic anion transporter family member 1B1	transporter
Lenvatinib	Bile salt export pump	transporter
Lenvatinib	Cytochrome P450 2D6	enzyme
Lenvatinib	Solute carrier organic anion transporter family member 1B3	transporter
Rifamycin	Cytochrome P450 3A4	enzyme
Rifamycin	Cytochrome P450 2C19	enzyme
Rifamycin	Cytochrome P450 2B6	enzyme
Rifamycin	Cytochrome P450 2C8	enzyme
Rifamycin	Cytochrome P450 2C9	enzyme
Rifamycin	Solute carrier organic anion transporter family member 1A2	transporter
Rifamycin	Solute carrier organic anion transporter family member 1B1	transporter
Rifamycin	Solute carrier organic anion transporter family member 1B3	transporter
Rifamycin	Solute carrier organic anion transporter family member 2A1	transporter
Rifamycin	Solute carrier organic anion transporter family member 2B1	transporter
Rifamycin	Serum albumin	carrier
Rifamycin	DNA-directed RNA polymerase subunit beta	target
Rifamycin	DNA-directed RNA polymerase subunit alpha	target
Rifamycin	DNA-directed RNA polymerase subunit beta'	target
Rifamycin	Multidrug and toxin extrusion protein 1	transporter
Rifamycin	Cytochrome P450 1A2	enzyme
Rifamycin	P-glycoprotein 1	transporter
Rifamycin	Cytochrome P450 2D6	enzyme
Rifamycin	DNA-directed RNA polymerase subunit beta	target
Rifamycin	DNA-directed RNA polymerase subunit beta'	target
Triclabendazole	Cytochrome P450 1A2	enzyme
Triclabendazole	Cytochrome P450 2C9	enzyme
Triclabendazole	Excretory Secretory (ES) proteins	target
Triclabendazole	Cytochrome P450 3A4	enzyme
Triclabendazole	Cytochrome P450 1A1	enzyme
Triclabendazole	Cytochrome P450 1B1	enzyme
Triclabendazole	Cytochrome P450 2C19	enzyme
Triclabendazole	Cytochrome P450 2D6	enzyme
Triclabendazole	Cytochrome P450 2A6	enzyme
Triclabendazole	Cytochrome P450 2C8	enzyme
Triclabendazole	Cytochrome P450 2B6	enzyme
Triclabendazole	Cruzipain	target
Paroxetine	Sodium-dependent serotonin transporter	target
Paroxetine	Sodium-dependent noradrenaline transporter	target
Paroxetine	5-hydroxytryptamine receptor 2A	target
Paroxetine	Cytochrome P450 2D6	enzyme
Paroxetine	Cytochrome P450 2C9	enzyme
Paroxetine	P-glycoprotein 1	transporter
Paroxetine	Cytochrome P450 2B6	enzyme
Paroxetine	Cytochrome P450 1A2	enzyme
Paroxetine	Cytochrome P450 3A4	enzyme
Paroxetine	Alpha-1 adrenergic receptors	target
Paroxetine	Alpha-2 adrenergic receptors	target
Paroxetine	Beta adrenergic receptor	target
Paroxetine	Dopamine D2 receptor	target
Paroxetine	Histamine H1 receptor	target
Paroxetine	Serotonin Receptors	target
Paroxetine	Muscarinic acetylcholine receptor	target
Paroxetine	5-hydroxytryptamine receptor 2B	target
Paroxetine	D(1) dopamine receptor	target
Paroxetine	Cytochrome P450 2C19	enzyme
Pexidartinib	Cytochrome P450 3A4	enzyme
Pexidartinib	UDP-glucuronosyltransferase 1-4	enzyme
Pexidartinib	Macrophage colony-stimulating factor 1 receptor	target
Pexidartinib	Cytochrome P450 2B6	enzyme
Pexidartinib	Cytochrome P450 2C9	enzyme
Pexidartinib	UDP-glucuronosyltransferase 1-1	enzyme
Pexidartinib	Multidrug and toxin extrusion protein 1	transporter
Pexidartinib	Multidrug and toxin extrusion protein 2	transporter
Pexidartinib	Solute carrier organic anion transporter family member 1B1	transporter
Pexidartinib	Solute carrier organic anion transporter family member 1B3	transporter
Pexidartinib	Solute carrier organic anion transporter family member 2B1	transporter
Pexidartinib	Serum albumin	carrier
Pexidartinib	Alpha-1-acid glycoprotein 1	carrier
Pexidartinib	Mast/stem cell growth factor receptor Kit	target
Pexidartinib	Receptor-type tyrosine-protein kinase FLT3	target
Pexidartinib	Platelet-derived growth factor receptor beta	target
Fluvoxamine	Sodium-dependent serotonin transporter	target
Fluvoxamine	Cytochrome P450 1A2	enzyme
Fluvoxamine	Cytochrome P450 2D6	enzyme
Fluvoxamine	Cytochrome P450 2C9	enzyme
Fluvoxamine	Cytochrome P450 2C19	enzyme
Fluvoxamine	Cytochrome P450 1A1	enzyme
Fluvoxamine	Cytochrome P450 3A4	enzyme
Fluvoxamine	Cytochrome P450 3A Subfamily	enzyme
Fluvoxamine	P-glycoprotein 1	transporter
Fluvoxamine	Cytochrome P450 2B6	enzyme
Fluvoxamine	Potassium voltage-gated channel subfamily H member 2	target
Fluvoxamine	Bile salt export pump	transporter
Modafinil	Sodium-dependent dopamine transporter	target
Modafinil	Alpha-1B adrenergic receptor	target
Modafinil	Cytochrome P450 3A4	enzyme
Modafinil	Cytochrome P450 2C19	enzyme
Modafinil	Cytochrome P450 1A2	enzyme
Modafinil	Cytochrome P450 2B6	enzyme
Modafinil	Cytochrome P450 2C9	enzyme
Modafinil	Cytochrome P450 3A5	enzyme
Modafinil	Cytochrome P450 2D6	enzyme
Curcumin sulfate	Peroxisome proliferator-activated receptor gamma	target
Curcumin sulfate	Vitamin D3 receptor	target
Curcumin sulfate	Multidrug resistance-associated protein 5	target
Curcumin sulfate	Carbonyl reductase [NADPH] 1	target
Curcumin sulfate	Glutathione S-transferase P	target
Curcumin sulfate	Cytochrome P450 2C9	enzyme
Curcumin sulfate	Cytochrome P450 2B6	enzyme
Curcumin sulfate	Cytochrome P450 1A2	enzyme
Curcumin sulfate	Cytochrome P450 2D6	enzyme
Curcumin sulfate	P-glycoprotein 1	transporter
Curcumin sulfate	Cytochrome P450 3A4	enzyme
Curcumin sulfate	Cytochrome P450 3A5	enzyme
Curcumin sulfate	UDP-glucuronosyltransferases (UGTs)	enzyme
Curcumin sulfate	Cytochrome P450 2C19	enzyme
Curcumin sulfate	Sulfotransferase 1A3/1A4	enzyme
Curcumin sulfate	Sulfotransferase family cytosolic 1B member 1	enzyme
Curcumin sulfate	Estrogen sulfotransferase	enzyme
Curcumin sulfate	Sulfotransferase 1C4	enzyme
Abemaciclib	Multidrug and toxin extrusion protein 1	transporter
Abemaciclib	Multidrug and toxin extrusion protein 2	transporter
Abemaciclib	Cyclin-dependent kinase 4	target
Abemaciclib	Cyclin-dependent kinase 6	target
Abemaciclib	Serum albumin	carrier
Abemaciclib	alpha1-acid glycoprotein	carrier
Abemaciclib	Cytochrome P450 3A4	enzyme
Abemaciclib	P-glycoprotein 1	transporter
Abemaciclib	ATP-binding cassette sub-family G member 2	transporter
Abemaciclib	Solute carrier family 22 member 2	transporter
Abemaciclib	Cytochrome P450 1A2	enzyme
Abemaciclib	Cytochrome P450 2B6	enzyme
Abemaciclib	Cytochrome P450 2C8	enzyme
Abemaciclib	Cytochrome P450 2C9	enzyme
Abemaciclib	Cytochrome P450 2D6	enzyme
Elexacaftor	Solute carrier organic anion transporter family member 1B1	transporter
Elexacaftor	Solute carrier organic anion transporter family member 1B3	transporter
Elexacaftor	P-glycoprotein 1	transporter
Elexacaftor	Serum albumin	carrier
Elexacaftor	Cytochrome P450 3A4	enzyme
Elexacaftor	Cytochrome P450 3A5	enzyme
Elexacaftor	Cytochrome P450 1A2	enzyme
Elexacaftor	Cytochrome P450 2B6	enzyme
Elexacaftor	Cytochrome P450 2C8	enzyme
Elexacaftor	Cytochrome P450 2C9	enzyme
Elexacaftor	Cytochrome P450 2C19	enzyme
Elexacaftor	Cytochrome P450 2D6	enzyme
Elexacaftor	Cystic fibrosis transmembrane conductance regulator	target
Cenobamate	UDP-glucuronosyltransferase 2B7	enzyme
Cenobamate	UDP-glucuronosyltransferase 2B4	enzyme
Cenobamate	Cytochrome P450 2E1	enzyme
Cenobamate	Cytochrome P450 2A6	enzyme
Cenobamate	Cytochrome P450 2B6	enzyme
Cenobamate	Cytochrome P450 2C19	enzyme
Cenobamate	Cytochrome P450 3A4	enzyme
Cenobamate	Cytochrome P450 3A5	enzyme
Cenobamate	Serum albumin	carrier
Cenobamate	Cytochrome P450 2C8	enzyme
Sertraline	Sodium-dependent serotonin transporter	target
Sertraline	Cytochrome P450 2B6	enzyme
Sertraline	Cytochrome P450 2C19	enzyme
Sertraline	Cytochrome P450 2C9	enzyme
Sertraline	Cytochrome P450 2D6	enzyme
Sertraline	Sodium-dependent dopamine transporter	target
Sertraline	CYP2B protein	enzyme
Sertraline	Cytochrome P450 3A4	enzyme
Sertraline	Amine oxidase [flavin-containing] B	enzyme
Sertraline	Amine oxidase [flavin-containing] A	enzyme
Sertraline	P-glycoprotein 1	transporter
Sertraline	Serum albumin	carrier
Sertraline	Sigma receptor	target
Sertraline	Sodium-dependent noradrenaline transporter	target
Sertraline	Equilibrative nucleoside transporter 4	target
Sertraline	Cytochrome P450 2E1	enzyme
Lopinavir	Human immunodeficiency virus type 1 protease	target
Lopinavir	Cytochrome P450 3A4	enzyme
Lopinavir	Cytochrome P450 2D6	enzyme
Lopinavir	Cytochrome P450 2C19	enzyme
Lopinavir	P-glycoprotein 1	transporter
Lopinavir	Cytochrome P450 2B6	enzyme
Lopinavir	Cytochrome P450 2C9	enzyme
Lopinavir	Cytochrome P450 3A Subfamily	enzyme
Lopinavir	Solute carrier organic anion transporter family member 1B1	transporter
Lopinavir	Solute carrier organic anion transporter family member 1B3	transporter
Lopinavir	Bile salt export pump	transporter
Lopinavir	Cytochrome P450 1A2	enzyme
Lopinavir	Alpha-1-acid glycoprotein 1	carrier
Lopinavir	Serum albumin	carrier
Ritonavir	Human immunodeficiency virus type 1 protease	target
Ritonavir	Cytochrome P450 2D6	enzyme
Ritonavir	Cytochrome P450 2C9	enzyme
Ritonavir	Cytochrome P450 2C19	enzyme
Ritonavir	Cytochrome P450 2B6	enzyme
Ritonavir	Cytochrome P450 2C8	enzyme
Ritonavir	P-glycoprotein 1	transporter
Ritonavir	Multidrug resistance-associated protein 1	transporter
Ritonavir	Canalicular multispecific organic anion transporter 1	transporter
Ritonavir	Solute carrier organic anion transporter family member 1A2	transporter
Ritonavir	ATP-binding cassette sub-family G member 2	transporter
Ritonavir	Solute carrier organic anion transporter family member 1B1	transporter
Ritonavir	Cytochrome P450 1A2	enzyme
Ritonavir	Nuclear receptor subfamily 1 group I member 2	target
Ritonavir	Serum albumin	carrier
Ritonavir	Cytochrome P450 3A4	enzyme
Ritonavir	Cytochrome P450 3A5	enzyme
Ritonavir	Cytochrome P450 3A7	enzyme
Ritonavir	UDP-glucuronosyltransferases (UGTs)	enzyme
Ritonavir	Solute carrier organic anion transporter family member 2B1	transporter
Ritonavir	Bile salt export pump	transporter
Ritonavir	Alpha-1-acid glycoprotein 1	carrier
Ritonavir	Solute carrier organic anion transporter family member 1B3	transporter
Ritonavir	Gag-Pol polyprotein	target
Methylene blue	Guanylate cyclase soluble subunit alpha-2	target
Methylene blue	Nitric oxide synthase, brain	target
Methylene blue	UDP-glucuronosyltransferase 1-4	enzyme
Methylene blue	UDP-glucuronosyltransferase 1-9	enzyme
Methylene blue	Cytochrome P450 1A2	enzyme
Methylene blue	Cytochrome P450 2B6	enzyme
Methylene blue	Cytochrome P450 2C8	enzyme
Methylene blue	Cytochrome P450 2C9	enzyme
Methylene blue	Cytochrome P450 2C19	enzyme
Methylene blue	Cytochrome P450 3A4	enzyme
Methylene blue	Cytochrome P450 3A5	enzyme
Methylene blue	Serum albumin	carrier
Methylene blue	P-glycoprotein 1	transporter
Methylene blue	Solute carrier family 22 member 2	transporter
Methylene blue	Multidrug and toxin extrusion protein 2	transporter
Methylene blue	Multidrug and toxin extrusion protein 1	transporter
Methylene blue	Flavin reductase (NADPH)	enzyme
Methylene blue	Cytochrome P450 2D6	enzyme
Abametapir	Cytochrome P450 1A2	enzyme
Abametapir	Cytochrome P450 3A4	enzyme
Abametapir	Cytochrome P450 2B6	enzyme
Dabrafenib	Cytochrome P450 3A4	enzyme
Dabrafenib	Cytochrome P450 2C8	enzyme
Dabrafenib	P-glycoprotein 1	transporter
Dabrafenib	ATP-binding cassette sub-family G member 2	transporter
Dabrafenib	Solute carrier organic anion transporter family member 1B1	transporter
Dabrafenib	Solute carrier organic anion transporter family member 1B3	transporter
Dabrafenib	Solute carrier family 22 member 6	transporter
Dabrafenib	Solute carrier family 22 member 8	transporter
Dabrafenib	Serine/threonine-protein kinase B-raf	target
Dabrafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Dabrafenib	Serine/threonine-protein kinase SIK1	target
Dabrafenib	Serine/threonine-protein kinase Nek11	target
Dabrafenib	LIM domain kinase 1	target
Dabrafenib	Cytochrome P450 2B6	enzyme
Dabrafenib	Cytochrome P450 2C9	enzyme
Dabrafenib	Cytochrome P450 2C19	enzyme
Dabrafenib	Cytochrome P450 1A2	enzyme
Dabrafenib	Serum albumin	carrier
Dabrafenib	Solute carrier organic anion transporter family member 1A2	transporter
Dabrafenib	Solute carrier family 22 member 2	transporter
Dabrafenib	UDP-glucuronosyltransferase 1-1	enzyme
Opicapone	Cytochrome P450 2C19	enzyme
Opicapone	Cytochrome P450 2C8	enzyme
Opicapone	Catechol O-methyltransferase	target
Opicapone	Solute carrier organic anion transporter family member 1B1	transporter
Opicapone	P-glycoprotein 1	transporter
Opicapone	ATP-binding cassette sub-family G member 2	transporter
Opicapone	Solute carrier organic anion transporter family member 1B3	transporter
Opicapone	Solute carrier organic anion transporter family member 2B1	transporter
Opicapone	Cytochrome P450 2C9	enzyme
Opicapone	Cytochrome P450 1A2	enzyme
Opicapone	Cytochrome P450 2B6	enzyme
Menadione	Prothrombin	target
Menadione	Vitamin K epoxide reductase complex subunit 1	target
Menadione	Coagulation factor IX	target
Menadione	Vitamin K-dependent gamma-carboxylase	target
Menadione	Vitamin K-dependent protein C	target
Menadione	Vitamin K-dependent protein S	target
Menadione	NAD(P)H dehydrogenase [quinone] 1	target
Menadione	Ribosyldihydronicotinamide dehydrogenase [quinone]	target
Menadione	Vitamin K epoxide reductase complex subunit 1-like protein 1	target
Menadione	Xanthine dehydrogenase/oxidase	enzyme
Menadione	Aldehyde oxidase	enzyme
Menadione	Methylenetetrahydrofolate reductase	enzyme
Menadione	Cytochrome P450 1A1	enzyme
Menadione	Osteocalcin	target
Menadione	Cytochrome P450 1A2	enzyme
Menadione	Cytochrome P450 2A6	enzyme
Menadione	Cytochrome P450 1B1	enzyme
Menadione	Cytochrome P450 2B6	enzyme
Menadione	Cytochrome P450 2C8	enzyme
Menadione	Cytochrome P450 2C9	enzyme
Menadione	Cytochrome P450 2C19	enzyme
Menadione	Cytochrome P450 2D6	enzyme
Menadione	Cytochrome P450 2E1	enzyme
Menadione	Cytochrome P450 3A4	enzyme
Menadione	Cytochrome P450 3A5	enzyme
Menadione	Cytochrome P450 3A7	enzyme
Menadione	Aldehyde oxidase	target
Duloxetine	Sodium-dependent serotonin transporter	target
Duloxetine	Sodium-dependent dopamine transporter	target
Duloxetine	Sodium-dependent noradrenaline transporter	target
Duloxetine	Cytochrome P450 1A2	enzyme
Duloxetine	Cytochrome P450 2D6	enzyme
Duloxetine	Cytochrome P450 2C9	enzyme
Duloxetine	Serum albumin	carrier
Duloxetine	alpha1-acid glycoprotein	carrier
Duloxetine	P-glycoprotein 1	transporter
Duloxetine	Cytochrome P450 3A4	enzyme
Duloxetine	Cytochrome P450 2B6	enzyme
Duloxetine	Cytochrome P450 2C19	enzyme
Brincidofovir	Leukotriene-B(4) omega-hydroxylase 1	enzyme
Brincidofovir	Sphingomyelin phosphodiesterase	enzyme
Brincidofovir	DNA polymerase	target
Brincidofovir	Cytochrome P450 1A2	enzyme
Brincidofovir	Cytochrome P450 2B6	enzyme
Brincidofovir	Cytochrome P450 2C8	enzyme
Brincidofovir	Cytochrome P450 2C9	enzyme
Brincidofovir	Cytochrome P450 2C19	enzyme
Brincidofovir	Cytochrome P450 2D6	enzyme
Brincidofovir	ATP-binding cassette sub-family G member 2	transporter
Brincidofovir	Canalicular multispecific organic anion transporter 1	transporter
Brincidofovir	Bile salt export pump	transporter
Brincidofovir	Solute carrier organic anion transporter family member 1B1	transporter
Brincidofovir	Solute carrier family 22 member 6	transporter
Brincidofovir	Solute carrier family 22 member 8	transporter
Brincidofovir	Solute carrier organic anion transporter family member 1B3	transporter
Brincidofovir	Variola virus DNA	target
Brincidofovir	DNA polymerase theta	target
Brincidofovir	DNA polymerase beta	target
Brincidofovir	DNA polymerase subunit gamma-2, mitochondrial	target
Brincidofovir	DNA polymerase subunit gamma-1	target
Brincidofovir	DNA polymerase epsilon subunit 2	target
Fexinidazole	Cytochrome P450 1A2	enzyme
Fexinidazole	Cytochrome P450 2B6	enzyme
Fexinidazole	Cytochrome P450 2C19	enzyme
Fexinidazole	Cytochrome P450 3A4	enzyme
Fexinidazole	Cytochrome P450 3A5	enzyme
Fexinidazole	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Fexinidazole	Cytochrome P450 2D6	enzyme
Fexinidazole	Solute carrier organic anion transporter family member 1B1	transporter
Fexinidazole	Solute carrier organic anion transporter family member 1B3	transporter
Fexinidazole	Solute carrier family 22 member 2	transporter
Fexinidazole	Solute carrier family 22 member 6	transporter
Fexinidazole	Solute carrier family 22 member 8	transporter
Fexinidazole	Multidrug and toxin extrusion protein 1	transporter
Fexinidazole	Multidrug and toxin extrusion protein 2	transporter
Levoketoconazole	Cytochrome P450 11B1, mitochondrial	target
Levoketoconazole	Lanosterol 14-alpha demethylase	target
Levoketoconazole	Cytochrome P450 3A4	enzyme
Levoketoconazole	Cytochrome P450 3A5	enzyme
Levoketoconazole	Steroid 21-hydroxylase	enzyme
Levoketoconazole	P-glycoprotein 1	transporter
Levoketoconazole	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Levoketoconazole	Cytochrome P450 11B2, mitochondrial	target
Levoketoconazole	Cholesterol side-chain cleavage enzyme, mitochondrial	target
Levoketoconazole	Solute carrier family 22 member 2	transporter
Levoketoconazole	Multidrug and toxin extrusion protein 1	transporter
Levoketoconazole	Cytochrome P450 2B6	enzyme
Levoketoconazole	Cytochrome P450 2C8	enzyme
Levoketoconazole	Cytochrome P450 1A2	enzyme
Levoketoconazole	Cytochrome P450 7A1	enzyme
Levoketoconazole	Cytochrome P450 19A1	enzyme
Dronabinol	Cannabinoid receptor 1	target
Dronabinol	Cytochrome P450 3A4	enzyme
Dronabinol	Cytochrome P450 2C9	enzyme
Dronabinol	Cannabinoid receptor 2	target
Dronabinol	P-glycoprotein 1	transporter
Dronabinol	ATP-binding cassette sub-family G member 2	transporter
Dronabinol	Prostaglandin G/H synthase 1	enzyme
Dronabinol	Cytochrome P450 2C19	enzyme
Dronabinol	Cytochrome P450 1A1	enzyme
Dronabinol	Cytochrome P450 1A2	enzyme
Dronabinol	Cytochrome P450 1B1	enzyme
Dronabinol	Cytochrome P450 2A6	enzyme
Dronabinol	Cytochrome P450 2B6	enzyme
Dronabinol	Cytochrome P450 2D6	enzyme
Dronabinol	Cytochrome P450 2J2	enzyme
Dronabinol	Cytochrome P450 3A5	enzyme
Dronabinol	Cytochrome P450 3A7	enzyme
Dronabinol	Multidrug resistance-associated protein 1	transporter
Dronabinol	Liver carboxylesterase 1	enzyme
Dronabinol	UDP-glucuronosyltransferase 1-1	enzyme
Dronabinol	UDP-glucuronosyltransferase 1-3	enzyme
Dronabinol	UDP-glucuronosyltransferase 1-9	enzyme
Dronabinol	UDP-glucuronosyltransferase 1-10	enzyme
Cannabidiol	Cytochrome P450 2C9	enzyme
Cannabidiol	Cytochrome P450 2C19	enzyme
Cannabidiol	Cytochrome P450 2D6	enzyme
Cannabidiol	Cytochrome P450 3A4	enzyme
Cannabidiol	Cannabinoid receptor 1	target
Cannabidiol	Cannabinoid receptor 2	target
Cannabidiol	G-protein coupled receptor 12	target
Cannabidiol	Glycine receptor subunit alpha-1	target
Cannabidiol	Glycine receptor (alpha-1/beta)	target
Cannabidiol	Glycine receptor subunit alpha-3	target
Cannabidiol	N-arachidonyl glycine receptor	target
Cannabidiol	G-protein coupled receptor 55	target
Cannabidiol	5-hydroxytryptamine receptor 1A	target
Cannabidiol	5-hydroxytryptamine receptor 2A	target
Cannabidiol	Neuronal acetylcholine receptor subunit alpha-7	target
Cannabidiol	Delta-type opioid receptor	target
Cannabidiol	Mu-type opioid receptor	target
Cannabidiol	Peroxisome proliferator-activated receptor gamma	target
Cannabidiol	Cytochrome P450 3A5	enzyme
Cannabidiol	Serotonin N-acetyltransferase	enzyme
Cannabidiol	Cytochrome P450 1A1	enzyme
Cannabidiol	Fatty-acid amide hydrolase 1	enzyme
Cannabidiol	Arachidonate 5-lipoxygenase	enzyme
Cannabidiol	Arachidonate 15-lipoxygenase	enzyme
Cannabidiol	Quinone oxidoreductase	enzyme
Cannabidiol	Multidrug resistance-associated protein 1	transporter
Cannabidiol	ATP-binding cassette sub-family G member 2	transporter
Cannabidiol	Equilibrative nucleoside transporter 1	transporter
Cannabidiol	Transient receptor potential cation channel subfamily V member 1	target
Cannabidiol	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Cannabidiol	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Cannabidiol	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Cannabidiol	Transient receptor potential cation channel subfamily A member 1	target
Cannabidiol	Transient receptor potential cation channel subfamily M member 8	target
Cannabidiol	Transient receptor potential cation channel subfamily V member 2	target
Cannabidiol	Transient receptor potential cation channel subfamily V member 3	target
Cannabidiol	Transient receptor potential cation channel subfamily V member 4	target
Cannabidiol	Voltage-dependent anion-selective channel protein 1	target
Cannabidiol	5-hydroxytryptamine receptor 3A	target
Cannabidiol	Adenosine receptor A1	target
Cannabidiol	Prostaglandin G/H synthase 1	target
Cannabidiol	Prostaglandin G/H synthase 2	target
Cannabidiol	Acetyl-CoA acetyltransferase, mitochondrial	target
Cannabidiol	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Cannabidiol	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Cannabidiol	Glutathione reductase, mitochondrial	target
Cannabidiol	Glutathione peroxidase 1	target
Cannabidiol	Indoleamine 2,3-dioxygenase 1	target
Cannabidiol	Cytochrome P450 1B1	target
Cannabidiol	NAD(P)H dehydrogenase [quinone] 1	target
Cannabidiol	Catalase	target
Cannabidiol	Cytochrome P450 3A5	target
Cannabidiol	Cytochrome P450 2D6	target
Cannabidiol	Superoxide dismutase [Cu-Zn]	target
Cannabidiol	Cytochrome P450 1A2	target
Cannabidiol	Cytochrome P450 3A7	target
Cannabidiol	Serotonin N-acetyltransferase	target
Cannabidiol	N-acylethanolamine-hydrolyzing acid amidase	target
Cannabidiol	Cytochrome P450 1A2	enzyme
Cannabidiol	Cytochrome P450 1B1	enzyme
Cannabidiol	Cytochrome P450 2A6	enzyme
Cannabidiol	Cytochrome P450 2B6	enzyme
Cannabidiol	Cytochrome P450 2C8	enzyme
Cannabidiol	Cytochrome P450 2E1	enzyme
Cannabidiol	Cytochrome P450 3A7	enzyme
Cannabidiol	UDP-glucuronosyltransferase 1-7	enzyme
Cannabidiol	UDP-glucuronosyltransferase 1-9	enzyme
Cannabidiol	UDP-glucuronosyltransferase 2B7	enzyme
Cannabidiol	UDP-glucuronosyltransferase 2B17	enzyme
Cannabidiol	P-glycoprotein 1	transporter
Cannabidiol	Cytochrome P450 2J2	enzyme
Cannabidiol	Liver carboxylesterase 1	enzyme
Cannabinol	Cytochrome P450 3A4	enzyme
Cannabinol	Cytochrome P450 2C19	enzyme
Cannabinol	Cytochrome P450 1A1	enzyme
Cannabinol	Cytochrome P450 1A2	enzyme
Cannabinol	Cytochrome P450 1B1	enzyme
Cannabinol	Cytochrome P450 2A6	enzyme
Cannabinol	Cytochrome P450 2B6	enzyme
Cannabinol	Cytochrome P450 2C9	enzyme
Cannabinol	Cytochrome P450 2D6	enzyme
Cannabinol	Cytochrome P450 3A5	enzyme
Cannabinol	Cytochrome P450 3A7	enzyme
Cannabinol	UDP-glucuronosyltransferase 1-7	enzyme
Cannabinol	UDP-glucuronosyltransferase 1-8	enzyme
Cannabinol	UDP-glucuronosyltransferase 1-9	enzyme
Cannabinol	UDP-glucuronosyltransferase 1-10	enzyme
Cannabinol	UDP-glucuronosyltransferase 2B7	enzyme
Cannabinol	P-glycoprotein 1	transporter
Cannabinol	ATP-binding cassette sub-family G member 2	transporter
Cannabinol	Multidrug resistance-associated protein 1	transporter
Cannabinol	Cytochrome P450 2E1	enzyme
Cannabinol	Cytochrome P450 2J2	enzyme
Cannabinol	Liver carboxylesterase 1	enzyme
Cannabinol	Cannabinoid receptor 1	target
Medical Cannabis	Cannabinoid receptor 1	target
Medical Cannabis	Cannabinoid receptor 2	target
Medical Cannabis	Cytochrome P450 2C9	enzyme
Medical Cannabis	Cytochrome P450 2C19	enzyme
Medical Cannabis	Cytochrome P450 2D6	enzyme
Medical Cannabis	Cytochrome P450 3A4	enzyme
Medical Cannabis	G-protein coupled receptor 12	target
Medical Cannabis	Glycine receptor subunit alpha-1	target
Medical Cannabis	Glycine receptor (alpha-1/beta)	target
Medical Cannabis	Glycine receptor subunit alpha-3	target
Medical Cannabis	N-arachidonyl glycine receptor	target
Medical Cannabis	G-protein coupled receptor 55	target
Medical Cannabis	5-hydroxytryptamine receptor 1A	target
Medical Cannabis	5-hydroxytryptamine receptor 2A	target
Medical Cannabis	Neuronal acetylcholine receptor subunit alpha-7	target
Medical Cannabis	Delta-type opioid receptor	target
Medical Cannabis	Mu-type opioid receptor	target
Medical Cannabis	Peroxisome proliferator-activated receptor gamma	target
Medical Cannabis	Cytochrome P450 3A5	enzyme
Medical Cannabis	Cytochrome P450 3A7	enzyme
Medical Cannabis	Cytochrome P450 1A1	enzyme
Medical Cannabis	Cytochrome P450 1A2	enzyme
Medical Cannabis	Cytochrome P450 1B1	enzyme
Medical Cannabis	Arachidonate 5-lipoxygenase	enzyme
Medical Cannabis	Arachidonate 15-lipoxygenase	enzyme
Medical Cannabis	Superoxide dismutase [Cu-Zn]	enzyme
Medical Cannabis	Multidrug resistance-associated protein 1	transporter
Medical Cannabis	ATP-binding cassette sub-family G member 2	transporter
Medical Cannabis	Equilibrative nucleoside transporter 1	transporter
Medical Cannabis	Transient receptor potential cation channel subfamily V member 1	target
Medical Cannabis	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Medical Cannabis	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Medical Cannabis	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Medical Cannabis	Transient receptor potential cation channel subfamily A member 1	target
Medical Cannabis	Transient receptor potential cation channel subfamily M member 8	target
Medical Cannabis	Transient receptor potential cation channel subfamily V member 2	target
Medical Cannabis	Transient receptor potential cation channel subfamily V member 3	target
Medical Cannabis	Transient receptor potential cation channel subfamily V member 4	target
Medical Cannabis	Voltage-dependent anion-selective channel protein 1	target
Medical Cannabis	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	target
Medical Cannabis	N-acylethanolamine-hydrolyzing acid amidase	target
Medical Cannabis	Serotonin N-acetyltransferase	target
Medical Cannabis	Phospholipase A2	target
Medical Cannabis	Superoxide dismutase [Cu-Zn]	target
Medical Cannabis	Fatty-acid amide hydrolase 1	target
Medical Cannabis	Catalase	target
Medical Cannabis	Quinone oxidoreductase	target
Medical Cannabis	Sphingomyelin phosphodiesterase	target
Medical Cannabis	Glutathione peroxidase 1	target
Medical Cannabis	Glutathione reductase, mitochondrial	target
Medical Cannabis	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Medical Cannabis	Indoleamine 2,3-dioxygenase 1	target
Medical Cannabis	Prostaglandin G/H synthase 1	target
Medical Cannabis	Prostaglandin G/H synthase 2	target
Medical Cannabis	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Medical Cannabis	Acetyl-CoA acetyltransferase, mitochondrial	target
Medical Cannabis	Cytochrome P450 2A6	enzyme
Medical Cannabis	Cytochrome P450 2B6	enzyme
Medical Cannabis	Cytochrome P450 2C8	enzyme
Medical Cannabis	Cytochrome P450 2E1	enzyme
Medical Cannabis	Cytochrome P450 2J2	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 1-7	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 1-8	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 1-9	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 1-10	enzyme
Medical Cannabis	UDP-glucuronosyltransferase 2B17	enzyme
Medical Cannabis	Liver carboxylesterase 1	enzyme
Medical Cannabis	P-glycoprotein 1	transporter
Medical Cannabis	UDP-glucuronosyltransferase 2B7	enzyme
Viloxazine	Sodium-dependent noradrenaline transporter	target
Viloxazine	Cytochrome P450 1A2	enzyme
Viloxazine	Cytochrome P450 2D6	enzyme
Viloxazine	UDP-glucuronosyltransferase 1-9	enzyme
Viloxazine	UDP-glucuronosyltransferase 2B15	enzyme
Viloxazine	Cytochrome P450 2B6	enzyme
Viloxazine	Cytochrome P450 3A4	enzyme
Viloxazine	Cytochrome P450 3A5	enzyme
Viloxazine	Multidrug and toxin extrusion protein 1	transporter
Viloxazine	5-hydroxytryptamine receptor 2B	target
Viloxazine	5-hydroxytryptamine receptor 2C	target
Viloxazine	Alpha-1B adrenergic receptor	target
Viloxazine	Beta-2 adrenergic receptor	target
Viloxazine	Amine oxidase [flavin-containing] A	target
Viloxazine	Amine oxidase [flavin-containing] B	target
Viloxazine	Histamine H1 receptor	target
Viloxazine	Histamine H2 receptor	target
Viloxazine	Muscarinic acetylcholine receptor M1	target
Viloxazine	Muscarinic acetylcholine receptor M2	target
Viloxazine	Muscarinic acetylcholine receptor M3	target
Viloxazine	Muscarinic acetylcholine receptor M4	target
Stiripentol	Cytochrome P450 2C19	enzyme
Stiripentol	Cytochrome P450 2D6	enzyme
Stiripentol	Cytochrome P450 3A4	enzyme
Stiripentol	Cytochrome P450 1A2	enzyme
Stiripentol	Cytochrome P450 2C9	enzyme
Stiripentol	GABA(A) Receptor	target
Stiripentol	L-lactate dehydrogenase A chain	target
Stiripentol	L-lactate dehydrogenase B chain	target
Stiripentol	Cytochrome P450 2B6	enzyme
Stiripentol	Cytochrome P450 2C8	enzyme
Stiripentol	P-glycoprotein 1	transporter
Stiripentol	ATP-binding cassette sub-family G member 2	transporter
Stiripentol	Gamma-aminobutyric acid receptor subunit gamma-3	target
Resveratrol	Transthyretin	carrier
Resveratrol	Ribosyldihydronicotinamide dehydrogenase [quinone]	target
Resveratrol	Prostaglandin G/H synthase 1	target
Resveratrol	Casein kinase II subunit alpha	target
Resveratrol	Prostaglandin G/H synthase 2	target
Resveratrol	NAD-dependent protein deacetylase sirtuin-1	target
Resveratrol	Cytochrome P450 1A1	enzyme
Resveratrol	Cytochrome P450 3A4	enzyme
Resveratrol	Cytochrome P450 1A2	enzyme
Resveratrol	Cytochrome P450 1B1	enzyme
Resveratrol	Arachidonate 15-lipoxygenase	target
Resveratrol	Arachidonate 5-lipoxygenase	target
Resveratrol	Aryl hydrocarbon receptor	target
Resveratrol	Phosphatidylinositol 4-kinase type 2-beta	target
Resveratrol	Integrin alpha-5	target
Resveratrol	Integrin beta-3	target
Resveratrol	Serum albumin	carrier
Resveratrol	Amyloid beta A4 protein	target
Resveratrol	Alpha-synuclein	target
Resveratrol	Estrogen receptor alpha	target
Resveratrol	Melatonin receptor type 1A	target
Resveratrol	Melatonin receptor type 1B	target
Resveratrol	C-type lectin domain family 14 member A	target
Resveratrol	Nuclear receptor subfamily 1 group I member 2	target
Resveratrol	Nuclear receptor subfamily 1 group I member 3	target
Resveratrol	Solute carrier family 2, facilitated glucose transporter member 1	target
Resveratrol	Carbonyl reductase [NADPH] 1	target
Resveratrol	Peroxisome proliferator-activated receptor alpha	target
Resveratrol	Peroxisome proliferator-activated receptor gamma	target
Resveratrol	RAC-alpha serine/threonine-protein kinase	target
Resveratrol	Far upstream element-binding protein 2	target
Resveratrol	Tyrosine--tRNA ligase, cytoplasmic	target
Resveratrol	Cytochrome P450 2D6	enzyme
Resveratrol	Cytochrome P450 2B6	enzyme
Resveratrol	Cytochrome P450 2C19	enzyme
Resveratrol	Cytochrome P450 2C9	enzyme
Pirtobrutinib	Cytochrome P450 3A4	enzyme
Pirtobrutinib	UDP-glucuronosyltransferase 1-8	enzyme
Pirtobrutinib	UDP-glucuronosyltransferase 1-9	enzyme
Pirtobrutinib	Cytochrome P450 2C8	enzyme
Pirtobrutinib	Cytochrome P450 2C9	enzyme
Pirtobrutinib	Cytochrome P450 1A2	enzyme
Pirtobrutinib	Cytochrome P450 2B6	enzyme
Pirtobrutinib	Cytochrome P450 2C19	enzyme
Pirtobrutinib	Cytochrome P450 2D6	enzyme
Pirtobrutinib	Cytochrome P450 3A5	enzyme
Pirtobrutinib	Tyrosine-protein kinase BTK	target
Pirtobrutinib	P-glycoprotein 1	transporter
Pirtobrutinib	ATP-binding cassette sub-family G member 2	transporter
Tezacaftor	Cytochrome P450 3A4	enzyme
Tezacaftor	Cytochrome P450 3A5	enzyme
Tezacaftor	Cystic fibrosis transmembrane conductance regulator	target
Tezacaftor	P-glycoprotein 1	transporter
Tezacaftor	ATP-binding cassette sub-family G member 2	transporter
Tezacaftor	Solute carrier family 22 member 2	transporter
Tezacaftor	Solute carrier family 22 member 6	transporter
Tezacaftor	Solute carrier family 22 member 8	transporter
Tezacaftor	Solute carrier organic anion transporter family member 1B1	transporter
Tezacaftor	Cytochrome P450 1A2	enzyme
Tezacaftor	Cytochrome P450 2B6	enzyme
Tezacaftor	Cytochrome P450 2C8	enzyme
Tezacaftor	Cytochrome P450 2C9	enzyme
Tezacaftor	Cytochrome P450 2C19	enzyme
Tezacaftor	Cytochrome P450 2D6	enzyme
Tezacaftor	Solute carrier organic anion transporter family member 1B3	transporter
Encorafenib	Cytochrome P450 3A4	enzyme
Encorafenib	Cytochrome P450 2C19	enzyme
Encorafenib	Cytochrome P450 2D6	enzyme
Encorafenib	Serine/threonine-protein kinase B-raf	target
Encorafenib	G1/S-specific cyclin-D1	target
Encorafenib	UDP-glucuronosyltransferase 1-1	enzyme
Encorafenib	Serum albumin	carrier
Encorafenib	Cytochrome P450 1A2	enzyme
Encorafenib	Cytochrome P450 2B6	enzyme
Encorafenib	Cytochrome P450 2C8	enzyme
Encorafenib	Cytochrome P450 2C9	enzyme
Encorafenib	Cytochrome P450 3A5	enzyme
Encorafenib	Cytochrome P450 3A7	enzyme
Encorafenib	P-glycoprotein 1	transporter
Encorafenib	Solute carrier family 22 member 2	transporter
Encorafenib	ATP-binding cassette sub-family G member 2	transporter
Encorafenib	Solute carrier family 22 member 6	transporter
Encorafenib	Solute carrier family 22 member 8	transporter
Encorafenib	Solute carrier organic anion transporter family member 1B1	transporter
Encorafenib	Solute carrier organic anion transporter family member 1B3	transporter
Encorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Encorafenib	Mitogen-activated protein kinase 8	target
Encorafenib	Mitogen-activated protein kinase 9	target
Encorafenib	Mitogen-activated protein kinase 10	target
Encorafenib	LIM domain kinase 1	target
Encorafenib	LIM domain kinase 2	target
Encorafenib	Dual specificity mitogen-activated protein kinase kinase 4	target
Encorafenib	Serine/threonine-protein kinase 36	target
Mavorixafor	C-X-C chemokine receptor type 4	target
Mavorixafor	Cytochrome P450 3A4	enzyme
Mavorixafor	Cytochrome P450 2D6	enzyme
Mavorixafor	Cytochrome P450 3A5	enzyme
Mavorixafor	Cytochrome P450 2C19	enzyme
Mavorixafor	Cytochrome P450 2B6	enzyme
Mavorixafor	Cytochrome P450 1A2	enzyme
Mavorixafor	Cytochrome P450 2C8	enzyme
Mavorixafor	Cytochrome P450 2C9	enzyme
Mavorixafor	P-glycoprotein 1	transporter
Mavorixafor	Solute carrier family 22 member 2	transporter
Mavorixafor	Multidrug and toxin extrusion protein 1	transporter