Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator
- Name
- Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator
- Accession Number
- DBCAT005803
- Description
Not Available
- Drugs
Drug Drug Description Ganaxolone A neuroactive steroid GABA-A receptor modulator used for the treatment of seizures associated with CDKL5 deficiency disorder (CDD). Brexanolone Brexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label][A176080, A176083, F4063, F4066, F4072]. Zuranolone A neuroactive steroid drug used to treat postpartum depression - Drugs & Drug Targets
Drug Target Type Ganaxolone GABA(A) Receptor target Ganaxolone Cytochrome P450 3A4 enzyme Ganaxolone Cytochrome P450 3A5 enzyme Ganaxolone Cytochrome P450 2B6 enzyme Ganaxolone Cytochrome P450 2C19 enzyme Ganaxolone Cytochrome P450 2D6 enzyme Brexanolone GABA(A) Receptor target Brexanolone Aldose reductase enzyme Zuranolone Cytochrome P450 3A4 enzyme Zuranolone GABA(A) Receptor target