Pseudomonas Infections (DBCOND0000438)

Identifiers

Synonyms

Pseudomonas / Infections, Pseudomonas / Pseudomonas Infection / Pseudomonas (organism) / Pseudomonas infection NOS / Bacterial infection due to Pseudomonas (disorder) / Pseudomonal infections

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Clavulanic acid	A beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.	Bacterial beta-lactamase enzymestarget Sodium/glucose cotransporter 1transporter Beta-lactamasetarget
Polymyxin B	A polymyxin antibiotic used to treat a wide variety of infections in the body.	Bacterial outer membranetarget Solute carrier family 15 member 2transporter Dihydropteroate synthasetarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT02894684	Aztreonam for Inhalation Solution (AZLI) for the Treatment of Exacerbations of Cystic Fibrosis	Aztreonam	treatment	4	completed
NCT06113107	Impact of Modifications to the Rendering of the Antibiogram on the Prescriptions of Meropenem in Pseudomonas Bacteremia	No drug interventions	Not Available	Not Available	recruiting
NCT04596319	Ph 1/2 Study Evaluating Safety and Tolerability of Inhaled AP-PA02 in Subjects With Chronic Pseudomonas Aeruginosa Lung Infections and Cystic Fibrosis	No drug interventions	treatment	1 / 2	completed
NCT01449838	Phase I Study of Colistin Methanesulfonate Sodium	Colistimethate	treatment	1	completed
NCT02178254	Safety, Tolerability and PK 3-Period Crossover Study Comparing 2 Single Doses of ZTI-01 and Monurol® in Healthy Subjects	Fosfomycin	treatment	1	completed
NCT00910351	Cipro Inhaler for Cystic Fibrosis Children Ages 6-12	Ciprofloxacin	treatment	1	completed
NCT00027183	Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa	No drug interventions	Not Available	Not Available	completed
NCT00529282	A Study of Ceftobiprole in Patients With Fever and Neutropenia.	Ceftobiprole medocaril	treatment	3	terminated
NCT00621803	Lcr35 / ICU / P. Aeruginosa	Bifidobacterium longum Lactobacillus acidophilus Lactobacillus casei	treatment	Not Available	terminated
NCT03510351	Clinical Outcomes With Ceftolozane-tazobactam for MDR Pseudomonas Infections	Ceftolozane Tazobactam	Not Available	Not Available	unknown_status
NCT03638830	Safety and Efficacy Study of Ftortiazinon in the Treatment of Patients With Complicated Urinary Tract Infections Caused by P. Aeruginosa	No drug interventions	treatment	2	unknown_status
NCT00014950	Benefits and Risks of Newborn Screening for Cystic Fibrosis	No drug interventions	diagnostic	Not Available	completed
NCT03044223	Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis	No drug interventions	Not Available	Not Available	recruiting
NCT00235690	Optimizing Dosing of Colistin for Infections Resistant to All Other Antibiotics, Approved NIH Protocol Dated 12.06.07(DMID Protocol #07-0036)	No drug interventions	prevention	Not Available	completed
NCT03715322	Tobramycin in Bronchiectasis Colonized With Pseudmonas Aeruginosa	Tobramycin	treatment	3	unknown_status
NCT00634192	Pharmacokinetic Evaluation of an 8 -Week Treatment With Inhaled Tobramycin	Tobramycin	treatment	3	completed
NCT00610623	Azithromycin as a Quorum-Sensing Inhibitor for the Prevention of Pseudomonas Aeruginosa Ventilator-Associated Pneumonia	Azithromycin	prevention	2	terminated