Trypanosomiasis (DBCOND0013916)

Identifiers

Synonyms

Chagas' disease (chronic) with heart involvement / Trypanosomiasis (disorder) / Trypanosomiasis, unspecified / Trypanosomiasis NOS

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Pentamidine	An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.	DNAtarget Cytochrome P450 2C19enzyme tRNA (cytosine(38)-C(5))-methyltransferasetarget Cytochrome P450 2D6enzyme Cytochrome P450 1A1enzyme Cytochrome P450 3A5enzyme Cytochrome P450 4A11enzyme Tryptase alpha/beta-1target

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01533961	Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158	Acoziborole	treatment	1	completed
NCT00123916	BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease	Benznidazole	treatment	3	completed