Chronic Bronchitis (DBCOND0029977)

Identifiers

Synonyms
Bronchitis chronic / Bronchitis, Chronic / Chronic bronchitis / Chronic bronchitis NOS / Chronic bronchitis, unspecified / Bronchitis chronic NOS / Unspecified chronic bronchitis / Chronic bronchitis (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Albuterol
A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
Almitrine
For the treatment of chronic obstructive pulmonary disease.
Aminophylline
A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
Bambuterol
A long acting beta2-adrenoceptor agonist for the management of lung diseases associated with bronchospasm.
Carbocisteine
A expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity.
Carmoterol
A long acting beta-2 agonist indicated in the treatment of COPD, asthma, and chronic bronchitis.
Dirithromycin
An antibiotic used to treat a variety of respiratory, skin, and other infections.
Dyphylline
A theophylline derivative used to treat asthma, bronchospasm, and COPD.
Etafedrine
A beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa.
Fluticasone propionate
A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
Glycopyrronium
An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia.
Guaifenesin
An expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.
Ipratropium
An anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
Orciprenaline
A beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
Oxtriphylline
A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema.
Procaterol
A beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Rufloxacin
A fluoroquinolone antibiotic indicated in the treatment of susceptible respiratory infections and uncomplicated cystitis.
Theophylline
A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
Tiotropium
A long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01077102
Eccentric Exercise Training as Novel Rehabilitation for Chronic Obstructive Pulmonary Disease (COPD)No drug interventionstreatmentNot Availablecompleted
NCT00932802
Greatest International Antiinfective Trial With AveloxNo drug interventionsNot AvailableNot Availablecompleted
NCT00726479
Safety and Efficacy of 4-weeks Treatment of BIBW 2948 BS in Patients With Chronic Obstructive BronchitisNo drug interventionstreatment2withdrawn
NCT02515799
Mucolytic Effectiveness of Tacholiquine ® in Chronic BronchitisNo drug interventionssupportive_care4completed
NCT02483637
Safety and Feasibility Study of Rejuvenair™ for Treating Chronic Bronchitis PatientsNo drug interventionstreatmentNot Availablecompleted
NCT02637219
Innate Immune Response in COPDNo drug interventionsNot AvailableNot Availablecompleted
NCT01515709
Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00538148
Telithromycin: in the Treatment of Acute Exacerbation of Chronic Bronchitis in Adult Outpatients With COPDNo drug interventionstreatment4completed
NCT00269932
A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Cefuroxime Axetil in the Treatment of Adults With Persistent Bronchitis Experiencing Rapid Onset of Severe Worsening of Symptoms Caused by Bacteriatreatment3completed
NCT00245453
Outpatient Registry Trial of Respiratory Tract Infections in Adultstreatment4withdrawn
NCT02261350
Post-hospitalisation Nutritional Support and Gait Speed in COPDNo drug interventionssupportive_care3terminated
NCT01495780
eRT Remote Health MonitoringNo drug interventionspreventionNot Availablecompleted
NCT01507415
Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?No drug interventionsNot AvailableNot Availablecompleted
NCT00871637
Airway Macrophages and Sputum Milieu in Adult Subjects With Airflow ObstructionNo drug interventionsNot AvailableNot Availablecompleted
NCT00846911
AVANTI - Avelox® in Acute Exacerbations of chroNic bronchiTIsNo drug interventionsNot AvailableNot Availablecompleted
NCT00644449
A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Acute Symptoms of Chronic BronchitisNo drug interventionstreatment3completed
NCT00649831
A Multicentre, Randomised, Open-Label Study To Compare The Efficacy And Safety Of Azithromycin For 5 Days With Those Of Amoxicillin-Clavulanic Acid In Patients With Chronic BronchitisNo drug interventionstreatment3completed
NCT00608764
Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00473460
Intermittent Moxifloxacin Therapy For The Prevention Of Acute Exacerbations In Patients With Chronic BronchitisNo drug interventionsprevention3completed
NCT00423137
Effect of BIBW 2948 BS in COPDNo drug interventionstreatment2completed
NCT00406705
The Effect of Breathing Helium-Hyperoxia During Pulmonary Rehabilitation in Patients With COPDNo drug interventionstreatment2completed
NCT00245427
Outcomes of Patients Not Responding to Antibiotics in the CommunityNo drug interventionsNot AvailableNot Availablecompleted
NCT00184977
COPD on Primary Care Treatment (COOPT)treatment4completed
NCT00035828
A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPDNo drug interventionstreatment2completed
NCT01719822
Physical Activity Augmentation Using Pedometers During Pulmonary Rehabilitation in Chronic Obstructive Pulmonary DiseaseNo drug interventionssupportive_careNot Availablecompleted
NCT00288223
Telithromycin in Acute Exacerbation of Chronic Bronchitistreatment4terminated
NCT00257140
A Study of the Safety and Effectiveness of Levofloxacin Compared With Cefaclor in the Treatment of Adults With Chronic Bronchitis Experiencing Rapid Onset of Worsening of Symptoms Caused by Bacteriatreatment2 / 3completed
NCT00974064
The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03228121
Crossover Blinded Trial of Cell Therapy Versus Placebo in COPDNo drug interventionstreatmentNot Availablewithdrawn
NCT02416102
Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic BronchitisNo drug interventionsbasic_science4terminated
NCT00298402
Macrophages in Smokers' LungNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01599884
N-Acetylcysteine for Patients With COPD and ChronicBronchitisNo drug interventionstreatmentNot Availableunknown_status
NCT01361984
Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed TomographyNo drug interventionstreatment4unknown_status
NCT01302587
A Study to Evaluate the Integrated Dose Counter on an Albuterol Hydrofluoroalkane (HFA) Metered Dose Inhaler (MDI)No drug interventionsNot AvailableNot Availablecompleted
NCT00656747
Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic BronchitisNo drug interventionstreatment4completed
NCT01420445
Safety/Tolerability and Efficacy of YHD001 in Patients With Acute and Chronic BronchitisNo drug interventionstreatment2completed
NCT02742597
Patient-Centred Innovations for Persons With Multimorbidity - OntarioNo drug interventionsotherNot Availablecompleted
NCT00255983
A Trial to Evaluate the Efficacy and Safety of Faropenem Medoxomil In the Treatment of Chronic Bronchitistreatment3terminated
NCT02341183
Novel Therapies for Muco-Obstructive Lung Diseases: Testing the Transnasal Pulmonary Delivery Device in COPD/CB SubjectsNo drug interventionsotherNot Availablewithdrawn
NCT01071161
The Effect of Azithromycin in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Productive CoughNo drug interventionstreatment3completed
NCT01792271
Sustained Effects of Hypertonic Saline on Mucociliary Clearance in Subjects With Chronic BronchitisNo drug interventionstreatmentNot Availablecompleted
NCT01828788
Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole CathetersNo drug interventionstreatment2completed
NCT05641207
A Clinical Evaluation of the RheOx Bronchial Rheoplasty SystemNo drug interventionstreatmentNot Availablerecruiting
NCT00338507
Phase 2 Study - Erdosteine in Patients With CB/COPDNo drug interventionstreatment2completed
NCT00680056
Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease PatientsNo drug interventionstreatment4completed
NCT03085485
The Topic Trial - Study to Determine the Safety and Efficacy of IvacaftorNo drug interventionstreatment2completed
NCT02895152
Activity Monitor Use in COPD Patients Undergoing RehabilitationNo drug interventionsotherNot Availablecompleted
NCT02061852
Evaluation of the Safety of the Medical Device Simeox®No drug interventionstreatmentNot Availableterminated
NCT02789800
Patient-Centred Innovations for Persons With Multimorbidity - QuebecNo drug interventionsotherNot Availablecompleted
NCT00454675
Pulmonary Function Changes in 10 Pack Year Smokers With Chronic BronchitisNo drug interventionsNot AvailableNot Availablecompleted
NCT03893370
RejuvenAir® System Trial for COPD With Chronic BronchitisNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00042718
A Study of the Effectiveness and Safety of High Dose, Short-course Levofloxacin in the Treatment of Acute Bacterial Exacerbation (Worsening) of Chronic Bronchitis.treatment3completed
NCT04182841
RheOx Registry Study in EuropeNo drug interventionstreatmentNot Availablerecruiting
NCT03385616
Gala Treatment for Chronic Bronchitis in CanadaNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT04631016
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic BronchitisNo drug interventionstreatment2completed
NCT00870896
The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease (COPD)No drug interventionstreatment0completed
NCT05337163
A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in ChinaNo drug interventionsNot AvailableNot Availablecompleted
NCT00683722
PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)No drug interventionstreatment2completed
NCT01431625
Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) PhenotypeNo drug interventionstreatment4unknown_status
NCT06086730
Comparison Of Blow Bottle Positive Expiratory Pressure (BBPEP) Versus Acapella Among Patient With Chronic BronchitisNo drug interventionstreatmentNot Availablecompleted
NCT05075057
Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Patients Aged ≥60 Years With Chronic Bronchitis and COPDNo drug interventionsprevention4unknown_status
NCT00720226
Efficacy of Losartan in Preventing Progression of COPDNo drug interventionstreatment4completed
NCT00254566
A Trial To Evaluate Two Antibiotics For The Treatment Of Acute Exacerbation Of Chronic Bronchitis (AECB)treatment3completed
NCT05533931
Resistive Breathing Versus Inspiratory Hold Technique in Patients With Chronic BronchitisNo drug interventionstreatmentNot Availableunknown_status
NCT04834531
Effect of Zhuli Capsule on Phlegm-heat Syndrome (Tan-re Zheng)No drug interventionstreatment4unknown_status
NCT00633776
Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT)No drug interventionstreatment4withdrawn
NCT02042976
Mindfulness-based Cognitive Therapy for Chronic Obstructive Pulmonary DiseaseNo drug interventionssupportive_careNot Availablecompleted
NCT03107494
Gala FIH Feasibility Study for the Treatment of Chronic BronchitisNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT03892694
Metered Cryospray for the Treatment of Patients With Chronic Obstructive Pulmonary Disease With Chronic BronchitisNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03010592
Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPDNo drug interventionsNot AvailableNot Availableunknown_status
NCT00051792
Yoga for Treating Shortness of Breath in Chronic Obstructive Pulmonary Disease (COPD)No drug interventionstreatment1 / 2completed
NCT02140892
A Comparison Study of Two Respiratory Physical Therapy Methods and Standard Medical Treatment for Treating COPD Patients During Acute ExacerbationNo drug interventionstreatmentNot Availableunknown_status
NCT01969344
Study of COPD Subgroups and BiomarkersNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03653104
Melodica Orchestra for Dyspnea: Safety and Feasibility PilotNo drug interventionstreatmentNot Availablewithdrawn
NCT02627872
Clinical & Systems Medicine Investigations of Smoking-related Chronic Obstructive Pulmonary DiseaseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00147069
Leukocyte Function in Asthma and COPDNo drug interventionsNot AvailableNot Availablecompleted
NCT05843669
A Study to Explore if Long-term Use of Mucinex Can Help With Symptoms in Patients With Stable Chronic Bronchitis.No drug interventionstreatment4recruiting
NCT04069312
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)No drug interventionsother4recruiting
NCT00307281
Emphysema Research Registry and Biosample RepositoryNo drug interventionsNot AvailableNot Availablerecruiting
NCT05610514
Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke CigarettesNo drug interventionsbasic_science2completed
NCT00903955
Mucus Dehydration and Evolution of Chronic Obstructive Pulmonary Disease (COPD) Lung DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT02838108
The Relationship Between GOLD Risk Group and Clinical Outcomes in a Community-based COPD CohortNo drug interventionsNot AvailableNot Availableterminated
NCT01739790
N-Acetylcysteine for Patients With COPD and Chronic BronchitisNo drug interventionstreatmentNot Availableterminated
NCT03657121
Mortality and Symptom Burden Post Hospitalisation With COPDNo drug interventionsNot AvailableNot Availablecompleted
NCT03049202
BROnchoalveolar Investigations of Never-smokers With Chronic Obstruction From the Swedish CardioPulmonary bioImage StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00064402
Determine the Safety and Efficacy of (R,R)-Formoterol in the Treatment of Subjects With COPDtreatment3completed
NCT00132951
KEYS: Study Comparing Clinical Health Outcomes of Telithromycin Versus Azithromycin in Outpatients With Community-acquired Lower Respiratory Tract Infectionstreatment4terminated
NCT00233051
Evaluating Genes in Sputum to Measure Drug Response in COPDtreatmentNot Availableterminated
NCT00876577
VICTOR - Avelox® Intravenous (i.v.) in Acute Exacerbations of Chronic BronchitisNo drug interventionsNot AvailableNot Availablecompleted
NCT00205647
Study of Expectorant Activity of Oral N-acetylcystein (NAC) in Patients With Stable Chronic BronchitisNo drug interventionstreatment2completed
NCT00642447
Helium:Oxygen Noninvasive Positive Pressure Ventilation in Patients Exposed to Sulfur MustardNo drug interventionssupportive_care2 / 3completed
NCT03073798
The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic BronchitisNo drug interventionstreatment4completed
NCT01130883
Evaluation of Effectiveness of the Treatment After Repeated Administration of Klacid®SRNo drug interventionsNot AvailableNot Availablecompleted
NCT05075083
Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Elderly People With Chronic Bronchitis and COPDNo drug interventionsprevention4unknown_status
NCT00129883
Adherence to Guidelines for Antibiotic Use in Respiratory Infections at HospitalsNo drug interventionseducational_counseling_trainingNot Availablecompleted
NCT03251911
VX-770 for the Treatment of Chronic BronchitisNo drug interventionstreatment4withdrawn
NCT04441788
A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)No drug interventionstreatment2terminated
NCT00181207
Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) ExacerbationNo drug interventionsprevention4completed
NCT01108185
Evaluation of the Treatment With Klacid®SR in Patients With Lower Respiratory Tract InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT00064415
To Evaluate the Long-term Safety of (R,R)-Formoterol in Subjects With COPDtreatment3completed
NCT00373932
Real-Time Support for Exercise Persistence in COPDNo drug interventionsNot Available1 / 2completed
NCT02803242
COPD Patient-Powered Research NetworkNo drug interventionsNot AvailableNot Availablerecruiting
NCT02099799
The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPDNo drug interventionstreatmentNot Availablecompleted
NCT00147017
Regulation of the Release of Inflammatory Mediators From Lung Macrophages.No drug interventionsNot AvailableNot Availablecompleted
NCT00153634
Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)treatmentNot Availablecompleted
NCT05104216
Immunogenicity and Safety of a Third Dose and Immune Persistence of BBIBP-Corv Vaccine in Elderly People With Chronic Bronchitis and COPDNo drug interventionsprevention4unknown_status
NCT00785239
CryoSpray Ablation(tm)Thoracic Patient RegistryNo drug interventionsNot AvailableNot Availablewithdrawn
NCT05646225
Early Mobilization With and Without Chest Physiotherapy in Chronic Bronchitis Patients.No drug interventionstreatmentNot Availablerecruiting
NCT00342030
Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese SingaporeansNo drug interventionsNot AvailableNot Availablecompleted
NCT04677465
Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic BronchitisNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00175565
Inhaled Steroid Reduces Systemic Inflammation in COPDtreatment4completed
NCT00147082
Leukocyte Function in Chronic Obstructive Pulmonary Disease (COPD)No drug interventionsNot AvailableNot Availablecompleted
NCT00106080
Improving the Quality of End-of-Life Communication for Patients With Chronic Obstructive Pulmonary Disease (COPD)No drug interventionsotherNot Availablecompleted
NCT02128529
Epidemiology of Chronic Bronchitis in Patients With Chronic Obstructive Pulmonary Disease (COPD)No drug interventionsNot AvailableNot Availablecompleted
NCT05771129
Feasibility Study of the Pulsed Electric Field Ablation System in Treating Chronic BronchitisNo drug interventionstreatmentNot Availablerecruiting
NCT00298389
Macrophage Phagocytosis in COPDNo drug interventionsNot AvailableNot Availablecompleted
NCT03631472
Gala Early Feasibility Study of RheOxNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05649046
Structuring of a Lung Cancer Screening Program Including Clinical, Radiological and Biological Phenotyping Useful for the Development of Individualized Risk Prediction Tools: PREVALUNG ETOILENo drug interventionspreventionNot Availableactive_not_recruiting
NCT06242210
Effects of Pursed Lip Breathing Technique Versus Stacked Breathing Technique Among Chronic Bronchitis PatientsNo drug interventionstreatmentNot Availablecompleted
NCT00524095
Bronchiectasis in Chronic Obstructive Pulmonary Disease (COPD) Patients: Role of ProphylaxisNo drug interventionsprevention2terminated
NCT00879008
SYMPROVE III: Health Services Research Study for Treatment of the Moderate and Severe Acute Exacerbations of Chronic Bronchitis (AECB)No drug interventionsNot AvailableNot Availablecompleted
NCT00132938
PERSPECTIVE: Telithromycin - Acute Exacerbation of Chronic Bronchitistreatment4completed