Pituitary Diseases (DBCOND0033121)

Identifiers

Synonyms

Pituitary Disease / Disorder of pituitary gland, unspecified / Pituitary disorder / Pituitary disorder NOS / Disorder of pituitary gland (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Somatotropin	A recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.	Growth hormone receptortarget Prolactin receptortarget Cytochrome P450 1A2enzyme Cytochrome P450 2C19enzyme ATP-dependent translocase ABCB1transporter

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03882034	Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess	Pegvisomant	treatment	3	recruiting
NCT04713293	China Pituitary Disease Registry (CAPASITY)	No drug interventions	Not Available	Not Available	recruiting
NCT00182091	Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency	Somatotropin	treatment	Not Available	completed
NCT03474601	Seoul National University Pituitary Disease Cohort Study	No drug interventions	Not Available	Not Available	recruiting
NCT00054756	Study of Thyrotropin-Releasing Hormone in Normal Volunteers and in Patients With Thyroid or Pituitary Abnormalities	Protirelin	diagnostic	2	completed
NCT00234533	Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq	Somatotropin	treatment	3	completed
NCT02084134	Peri-Operative Steroid Management in Patients	Dexamethasone Hydrocortisone	treatment	Not Available	completed
NCT03305016	A Safety, Tolerability and Efficacy Study of TransCon hGH in Children With Growth Hormone Deficiency	Somatotropin	treatment	3	completed
NCT04326374	Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Chinese Pediatric Growth Hormone Deficiency	Lonapegsomatropin Somatotropin	treatment	3	unknown_status
NCT02781727	A Phase 3 Trial of the Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)	Somatotropin	treatment	3	completed
NCT06435195	Clinical Characteristics and Analysis of Pituitary Complex and Rare Diseases	No drug interventions	Not Available	Not Available	recruiting
NCT02782208	Lipolytic Effects of GH in Hypopituitary Patients in Vivo	Acipimox	basic_science	Not Available	completed
NCT03665064	Long Term Outcome Study in Patients With Pituitary Disorders	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT04897802	Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)	Exenatide	diagnostic	4	recruiting
NCT03137615	The Cardiovascular Changes Associated With Septal Local Anaesthesia	No drug interventions	Not Available	Not Available	completed
NCT03344458	A Long-Term Trial Investigating Safety and Efficacy of TransCon hGH in Children With Growth Hormone Deficiency Who Have Completed a Prior TransCon hGH Clinical Trial	Somatotropin	treatment	3	completed
NCT04902235	Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study)	No drug interventions	diagnostic	4	completed
NCT04951557	Setting Benchmarks for Transsphenoidal Resection of Pituitary Adenomas	No drug interventions	Not Available	Not Available	unknown_status
NCT00473369	Prognosis of Atypical Pituitary Adenomas	No drug interventions	Not Available	Not Available	unknown_status