Non-Resectable Hepatocellular Carcinoma (DBCOND0045089)

Identifiers

Synonyms
Liver Cell Carcinoma Non-resectable / Hepatocellular Carcinoma Non-resectable / Hepatocellular carcinoma / Carcinoma hepatocellular / Hepatoma / Primary carcinoma of liver (disorder) / Liver carcinoma / (Liver carcinoma) or (Ca: [liver/biliary system] or [biliary system]) / Carcinoma liver / Liver cell carcinoma (disorder) / Hepatocellular carcinoma (morphologic abnormality) / Carcinoma of liver / Carcinoma, Hepatocellular

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06397222
Sintilimab Plus Bevacizumab and SIRT for Intermediate-advanced HCCNo drug interventionstreatment2recruiting
NCT02989922
A Study to Evaluate SHR-1210 in Subjects With Advanced HCCtreatment2completed
NCT03533920
Clinical Trial to Evaluate the Efficacy and Safety of UNI-DEB for Unresectable Hepatocellular CarcinomaNo drug interventionstreatmentNot Availablecompleted
NCT04967482
DEB-TACE vs. cTACE as Conversion Therapy for Unresectable Large HCCNo drug interventionstreatmentNot Availableunknown_status
NCT03138031
Percutaneous Ethanol Alcohol Injection for the Large and Unresectable Hepatocellular CarcinomaNo drug interventionstreatmentNot Availablecompleted
NCT05901194
Lenvatinib Treatment in Waiting List of Liver Transplantation After TACE Failure in Patients With Hepatocellular Carcinomatreatment1 / 2not_yet_recruiting
NCT05713994
Combined HAIC, TKI/Anti-VEGF and ICIs as Conversion Therapy for Unresectable Hepatocellular CarcinomaNot AvailableNot Availablerecruiting
NCT06133062
Atezolizumab and Bevacizumab With Proton Radiotherapy for Unresectable Hepatocellular Carcinomatreatment2recruiting
NCT04522544
Durvalumab and Tremelimumab in Combination With Either Y-90 SIRT or DEB-TACE for Intermediate Stage HCCtreatment2recruiting
NCT03379844
HEPAR Primary: Holmium-166-radioembolization in Hepatocellular Carcinoma PatientsNo drug interventionstreatment2completed
NCT03881501
Evaluate the Treatment With Sintilimab Injection Plus Endostar in Hepatocellular CarcinomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05543304
Predicting Response to Systemic Therapies for Hepatocellular Carcinoma(HCC)No drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05057104
Non-inferiority Study of Unresectable Hepatocelluar Carcinoma Receiving Stereotactic Radiotherapy Combined With Hepatic Arterial Chemoembolization Compared With Conversion HepatectomyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04966195
Stereotactic Body Radiotherapy Based Treatment for Hepatocellular Carcinoma With Extensive Portal Vein Tumor ThrombosisNo drug interventionstreatmentNot Availablecompleted
NCT04997850
The Safety and Efficacy of Transarterial Chemoembolization (TACE) + Lenvatinib + Programmed Cell Death Protein 1 (PD-1) Antibody of Advanced Unresectable Hepatocellular Carcinomatreatment1 / 2enrolling_by_invitation
NCT05717738
Combined TACE, TKI/Anti-VEGF and ICIs as Conversion Therapy for Advanced Hepatocellular CarcinomaNot AvailableNot Availablerecruiting
NCT04599790
TACE Combined With Lenvatinib and Sintilimab for Advanced HCCtreatment2completed
NCT04511455
Cabozantinib for Patients With Hepatocellular Carcinoma (HCC) Refractory to First Line Treatmenttreatment2active_not_recruiting
NCT06561399
Triple Therapy Sequential Radiotherapy in Unresectable HCC (TALENP003)Not AvailableNot Availablerecruiting
NCT05953337
Radioembolization Trial Utilizing Eye90 Microspheres™ for the Treatment of Hepatocellular Carcinoma (HCC)No drug interventionstreatmentNot Availablerecruiting
NCT06535737
A Phase 2, Single Arm Study of Cabozantinib in Patients With Hepatocellular Carcinoma Who Have Received Prior Atezolizumab and Bevacizumabtreatment2not_yet_recruiting
NCT06492395
Lenvatinib Plus DEB-TACE and HAIC vs. Lenvatinib Plus DEB-TACE for Large HCC With PVTTNo drug interventionstreatment3not_yet_recruiting
NCT06487663
TACE Combined With Immune Checkpoint Inhibitors for Liver Malignant TumorsNo drug interventionstreatmentNot Availablerecruiting
NCT04224636
Atezolizumab/Bevacizumab Followed by On-demand TACE or Initial Synchronous Treatment With TACE and Atezolizumab/Bevacizumabtreatment2recruiting
NCT06397235
DEB-TACE+RALOX-HAIC vs DEB-TACE for Large HCCNo drug interventionstreatment2recruiting
NCT06408753
Plasma Biomarker in Predicting Response and Toxicity in HCC Patients Treated With Checkpoint Inhibitors With or Without SBRTNo drug interventionsNot AvailableNot Availablecompleted
NCT04965454
Evaluation of Treatment Predictors Reflecting Beta-catenin Activation in Hepatocellular Carcinomaother2recruiting
NCT06375486
Ivonescimab Combined With HAIC for the Treatment of Unresectable Hepatocellular Carcinoma(uHCC).treatment2recruiting
NCT05797870
Selective Internal Radiation Therapy and 188Re-SSS Lipiodol Treatment for Liver Cancer (Lip-Re2)treatment2recruiting
NCT05911633
BioPearl™ Microspheres Loaded With Doxorubicin for the Treatment of Unresectable Hepatocellular Carcinoma (HCC)No drug interventionstreatmentNot Availablerecruiting
NCT06265883
Lenvatinib Plus DEB-TACE With/Without FOLFOX-HAIC for Large HCC With PVTTNo drug interventionsNot AvailableNot Availablecompleted
NCT06187961
Combined HAIC, Lenvatinib and Cadonilimab as Conversion Therapy for Unresectable Hepatocellular Carcinomatreatment2recruiting
NCT05031949
Hyperbaric Oxygen Therapy Combined Camrelizumab in Patients With Advanced/Metastatic Hepatocellular Carcinomatreatment1recruiting
NCT05497453
A Phase 1/2 Study to Evaluate OTX-2002 in Patients With Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association With the MYC Oncogenetreatment1 / 2recruiting
NCT04926376
Safety and Effectiveness of Eye90 Microspheres™ in the Treatment of Unresectable HCC and mCRCNo drug interventionstreatmentNot Availablecompleted
NCT06040177
Efficacy and Safety of SBRT Combined With Cardonilizumab and Lenvastinib in the Treatment of Unresectable Hepatocellular Carcinoma With Portal Vein Tumor Thrombustreatment1 / 2recruiting
NCT05985798
Sintilimab+Bevacizumab+TACE vs. Lenvatinib+TACE for Advanced HCCNo drug interventionstreatment3recruiting
NCT05992220
Atezolizumab Plus Bevacizumab Alone or Combined With External Beam Radiotherapy for HCC With Macrovascular Invasiontreatment2recruiting
NCT01009593
Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC)treatment3terminated
NCT02967887
Evaluation of Hepatic Arterial Infusion of Cisplatin and 5-FU in Biomarker Stratified HCCtreatment2unknown_status
NCT03277716
Microwave Ablation Combined With TACE in the Treatment of Unresectable Huge Hepatocellular Carcinoma HugeNo drug interventionstreatmentNot Availableunknown_status
NCT03283956
Safety and Efficacy of dRug-ElutiNg beADs Trans-arterial chemoEmbolization for Hepatocellular Carcinoma in TaiwanNo drug interventionsNot AvailableNot Availableunknown_status
NCT03563170
QUILT-3.072: NANT Hepatocellular Carcinoma (HCC) Vaccinetreatment1 / 2withdrawn
NCT03564405
Pilot Clinical Trial to Evaluate the UNI-DEB for Unresectable Hepatocellular CarcinomaNo drug interventionstreatmentNot Availablecompleted
NCT03652467
The Safety and Efficacy of Deferoxamine for Treating Unresectable Hepatocellular Carcinomatreatment1recruiting
NCT03807947
Radial Versus Femoral Access for Superselective Embolization of Hepatocellular CarcinomaNo drug interventionstreatmentNot Availableunknown_status
NCT03864211
Thermal Ablation Followed by Immunotherapy for HCCtreatment1 / 2active_not_recruiting
NCT04273100
PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of HCCtreatment2unknown_status
NCT04592029
TACE Combined With Sintilimab and Bevacizumab for Unresectable HCCtreatment1active_not_recruiting
NCT04599777
TACE Combined With Sorafenib and Tislelizumab for Advanced HCCtreatment2completed
NCT04718909
Regorafenib Plus Sintilimab vs. Regorafenib as the Second-line Treatment for HCCtreatment2active_not_recruiting
NCT04996914
Adjuvant Stereotactic Body Radiation Therapy After Trans-arterial Chemoembolization in Hepatocellular CarcinomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05114148
Individualized Dosimetry for Holmium-166-radioembolization in Patients With Unresectable Hepatocellular CarcinomaNo drug interventionstreatmentNot Availablerecruiting
NCT05390112
Cohort Study of Patients With Hepatocellular Carcinoma and Circulating Tumor DNA Monitoring of ChemoembolizationNo drug interventionsNot AvailableNot Availablerecruiting
NCT05530785
Radiotherapy + Sintilimab + Bevacizumab Biosimilar for uHCC With PVTTtreatmentNot Availablerecruiting
NCT05608213
Lenvatinib Plus I-125 Seed Brachytherapy vs. Lenvatinib for TACE-refractory HCCtreatment3recruiting
NCT05638438
Efficacy and Safety of Transarterial Therapies+Donafenib + Anti-PD-1 Antibody for uHCC: A Retrospective Real-world StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04967495
TACE Plus Multikinase Inhibitor and I-125 Seeds Brachytherapy for HCC With Branch PVTTNo drug interventionstreatmentNot Availablerecruiting
NCT05608200
Lenvatinib+Sintilimab+TACE vs. Lenvatinib+TACE for Advanced HCCtreatment3recruiting
NCT01891539
Observational Prospective Study on Chemoembolization With Doxorubicin for Unresectable Hepatocellular CarcinomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01835223
Tivozanib in Treating Patients With Liver Cancer That Is Metastatic or Cannot Be Removed by Surgerytreatment1 / 2completed
NCT05609448
MRI-guided Holmium-166 RadioembolizationNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT03044587
Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancertreatment2active_not_recruiting