Palmar-Plantar Erythrodysesthesia (DBCOND0046995)

Identifiers

Synonyms

Hand-foot Syndrome / Hand Foot Skin Syndrome / Palmar-Plantar Erythrodysesthesia Syndrome / Hand and Foot Syndrome / Palmar-plantar Erythrodysesthesia (PPE) / Hand-and-foot syndrome / Palmar-plantar erythrodysaesthesia syndrome / Hand and foot syndrome secondary to chemotherapy / Hand and foot syndrome secondary to sickle cell anaemia / Hand and foot syndrome secondary to sickle cell anemia / Hand-foot syndrome in sickle cell anemia (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06602167	Electroacupuncture Combined With Self-administered Acupressure for the Prevention of Capecitabine-Associated Hand-Foot Syndrome	No drug interventions	prevention	Not Available	not_yet_recruiting
NCT05327751	Possible Protective Effect of Celecoxib Against Capecitabine Induced Hand and Foot Syndrome in Patients With Colorectal Cancer	Capecitabine Celecoxib	prevention	3	recruiting
NCT05348278	Urea Cream Prevention for Capecitabine Associated Hand Foot Syndrome	Urea	prevention	2 / 3	unknown_status
NCT04979078	Photobiomodulation Therapy in the Management of Hand-foot Syndrome and Hand-foot Skin Reaction	No drug interventions	treatment	Not Available	recruiting
NCT06188000	Efficacy of Extra Virgin Olive Oil (EVOO) Supplementation on Hand-Foot Syndrome Incidence in Patients With Capecitabine	No drug interventions	prevention	Not Available	active_not_recruiting
NCT05165069	The Efficacy and Safety of Mecobalamin in the Prevention of Capecitabine Induced Hand Foot Syndrome	Mecobalamin	prevention	3	recruiting
NCT06583369	The Efficacy and Safety of Liangxue Ointment in the Treatment of Hand-foot Syndrome Caused by VEGFR-TKI Drugs	Urea	treatment	Not Available	recruiting
NCT01219023	Treatment of Palmar Plantar Erythrodysesthesia (PPE) With Topical Sildenafil	Sildenafil	treatment	1	completed
NCT00446147	Study of Pyridoxine for Hand-Foot Syndrome	Pyridoxine	prevention	3	completed
NCT04833998	Hydration Based on Thoitaine, Aloe Vera and Calendula, in the Prevention of Hand-Foot Syndrome in Patients Using Capecitabine	No drug interventions	prevention	2	unknown_status
NCT02794493	Treatment of Hand and Foot Syndrome With Traditional Chinese Medicine Formula LC09 in Patients Who Are Receiving Capecitabine for Colorectal and/or Breast Cancer	No drug interventions	treatment	3	completed
NCT05949307	The Efficacy of Acupuncture and Laser Acupuncture in Treating Chemotherapy or Target Therapy-induced Hand-foot Syndrome	No drug interventions	treatment	Not Available	not_yet_recruiting
NCT05641246	Effect of Topical Diclofenac on Clinical Outcome in Breast Cancer Patients Treated With Capecitabine	Diclofenac Urea	prevention	2	completed
NCT00767689	Vitamin B6 Can Prevent Hand and Foot Syndrome in Cancer Patients Capecitabine Chemotherapy	Pyridoxine	prevention	Not Available	terminated
NCT01609166	Effectiveness Allopurinol Topical Agent Prevention Capecitabine-induced Hand-foot Syndrome	Allopurinol	prevention	2	completed
NCT03173365	The Effect of Topical Brimonidine Tartrate on Hand-foot Syndrome (HFS) in Cancer Patients	Brimonidine	treatment	2	terminated
NCT04592731	Acetylated Natural Nucleotides in Treating Hand-foot Syndrome	No drug interventions	treatment	Not Available	completed
NCT05755646	Ice Plant Intensive Cream for the Prevention of Hand-Foot Syndrome in Breast Cancer: Pilot Randomized Controlled Trial	No drug interventions	prevention	Not Available	completed
NCT06586073	Topical Cosmetic Products for Hand and Foot Syndrome	No drug interventions	Not Available	Not Available	completed
NCT01097850	Topical Henna Preparation for the Treatment of Hand Foot Skin Syndrome	Lawsonia inermis leaf	treatment	2	withdrawn
NCT01316406	Safety and Efficacy Placebo Controlled Study of ATH008 Cream in PPES Patients Secondary to Capecitabine	No drug interventions	treatment	2	completed
NCT02625415	The Topical Application of Vitamin B6 in Palmar-Plantar Erythrodysesthesia	No drug interventions	supportive_care	Not Available	completed
NCT00486213	Pyridoxine in Preventing Hand-Foot Syndrome Caused by Capecitabine in Patients With Cancer	No drug interventions	prevention	3	terminated
NCT00559858	Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine for Advanced Colorectal Cancer or Breast Cancer	No drug interventions	supportive_care	3	unknown_status
NCT05939726	Efficacy and Safety of Moisturising Cream With or Without Vitamin E and Urea Cream in Palmar-plantar Erythrodysesthesia	No drug interventions	treatment	Not Available	recruiting
NCT00751101	Nicotine Patches in Reducing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine For Metastatic Breast Cancer	Nicotine	supportive_care	2	terminated
NCT00213993	Topical Antiperspirant for Hand-Foot Syndrome	No drug interventions	prevention	2	completed
NCT00992706	F511 Cream in Preventing Palmar-Plantar Erythrodysesthesia in Patients Receiving Doxorubicin Hydrochloride Liposome for Metastatic Breast Cancer	Doxorubicin	supportive_care	3	completed
NCT01100463	Study of 0.1% Uracil Topical Cream (UTC) for the Prevention of Hand-Foot Syndrome	Propylthiouracil	prevention	1 / 2	completed
NCT01751893	Testing the Effectiveness of Henna on Managing PPE	Lawsonia inermis leaf	supportive_care	Not Available	completed