Chemotherapy Induced Neutropenia (DBCOND0051348)

Identifiers

Synonyms

Neutropenia post-chemotherapy / Chemotherapy-Induced Neutropenia / Chemotherapy Associated Neutropenia / Chemotherapy induced neutropenia / Chemotherapy-induced neutropenia (disorder) / Neutropenia, unspecified / Neutropenia / Neutropenia (disorder) [Ambiguous] / Neutropenic disorder (disorder) / (Agranulocytosis) or (Kostmann's syndrome) or (neutropenia) / Neutropenias

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Pegfilgrastim	A recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy.	Granulocyte colony-stimulating factor receptortarget Neutrophil elastaseenzyme

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06537726	Breath Analysis for the Detection of Invasive Fungal Infections	No drug interventions	Not Available	Not Available	recruiting
NCT04227990	Plinabulin iv Solution in Prevention of TAC Induced Neutropenia	Cyclophosphamide Docetaxel Doxorubicin Pegfilgrastim Plinabulin	supportive_care	2	completed
NCT01569087	Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer	Empegfilgrastim Filgrastim	supportive_care	2	completed
NCT05245487	Danish Elder Lymphoma Patient Hematopoietic Investigation	No drug interventions	Not Available	Not Available	recruiting
NCT02251977	Effect of GM1 in Prevention of Oxaliplatin Induced Neurotoxicity in Stage II/III Colorectal Cancer	Capecitabine Fluorouracil Ganglioside GM1 Leucovorin	prevention	3	completed
NCT03793205	G-CSF for the Prevention of Febrile Neutropenia in Gynecologic Cancer Patients	Filgrastim	treatment	4	unknown_status
NCT02156388	Safety and Pharmacokinetic(PK) Study of GW003 to Metastatic Tumors	No drug interventions	treatment	1	completed
NCT03246009	Fusion Protein rHSA/GCSFclinical Study on Breast Cancer Patients	No drug interventions	treatment	1	completed
NCT01735175	Phase III Study Comparing the Efficacy and Safety of LA-EP2006 and Neulasta®	Pegfilgrastim	supportive_care	3	completed
NCT02692742	Efficacy and Safety Phase IIa Study of Myelo001 in Chemotherapy-Induced Neutropenia	No drug interventions	supportive_care	2	completed
NCT03102606	Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 3	Filgrastim Pegfilgrastim Plinabulin	treatment	3	completed
NCT03208816	Community-Led Action Research in Oncology: Improving Symptom Management	No drug interventions	supportive_care	Not Available	completed
NCT02104830	Study of the Efficacy and Safety of Empegfilgrastim for Neutropenia Prophylaxis in Breast Cancer Patients	Filgrastim	supportive_care	3	completed
NCT00837265	Balugrastim (Neugranin) in Breast Cancer Participants Receiving Doxorubicin/Docetaxel	Balugrastim Pegfilgrastim	supportive_care	2 / 3	completed
NCT04887831	Trilaciclib, a CDK 4/6 Inhibitor, in Patients With Advanced/Metastatic Bladder Cancer Receiving Chemotherapy Then Avelumab	Avelumab Carboplatin Cisplatin Gemcitabine Trilaciclib	treatment	2	terminated
NCT05512676	Trabectedin/Caelyx vs Cisplatin Hypersensitivity in Relapsed Ovarian Cancer Patients Allergic to Platinum	No drug interventions	Not Available	Not Available	completed
NCT02465801	Study of Recombinant Human Serum Albumin/Granulocyte Colony-Stimulating Factor Fusion Protein	No drug interventions	prevention	2	completed
NCT02532712	Study to Evaluate the Safety, Tolerability and PK of EC-18 After Oral Administration in Healthy Volunteers	Mosedipimod	treatment	1	completed
NCT02496143	A Safety and PK Study of EC-18 in Healthy Subjects	Mosedipimod	supportive_care	1	completed
NCT01126190	Neugranin in Breast Cancer Participants Receiving Doxorubicin/Docetaxel	Balugrastim Docetaxel Doxorubicin Pegfilgrastim	supportive_care	3	completed
NCT04914702	Feasibility and Comparison of Continuously Monitored Vital Signs in Pediatric Patients With Cancer.	No drug interventions	Not Available	Not Available	completed
NCT04460079	Safety and Effectiveness Assessment of PeGagen® (Pegfilgrastim) in the Prevention of Chemotherapy-induced FN	Pegfilgrastim	Not Available	Not Available	completed
NCT03559387	Randomized Phase 2, Dose-finding Efficacy, Safety Study of ANF-RHO™ Versus Neulasta® in Chemotherapy-Induced Neutropenia	Filgrastim Pegfilgrastim	treatment	2	terminated
NCT03294577	Plinabulin vs. Pegfilgrastim in Prevention of TAC Induced Neutropenia	Cyclophosphamide Docetaxel Doxorubicin Filgrastim Pegfilgrastim Plinabulin	supportive_care	3	active_not_recruiting
NCT00501332	Evaluation of Maxy-G34 in Breast Cancer Patients Treated With TAC (Docetaxel, Adriamycin, Cyclophosphamide) Chemotherapy	Filgrastim Maxy-G34	treatment	2	unknown_status
NCT04345900	Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 2	Filgrastim Pegfilgrastim Plinabulin	treatment	2	completed
NCT02725606	Study to Assess the Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of GW003 in Patients With Breast Cancer	Filgrastim	treatment	1	unknown_status
NCT01516736	Phase III Study Comparing the Efficacy and Safety of LA-EP2006 and Peg-Filgrastim	Pegfilgrastim	supportive_care	3	completed
NCT03701841	Efficacy, Safety and Cost-effectiveness of PEG-rhG-CSF for Primary vs Secondary Prophylaxis	No drug interventions	Not Available	Not Available	unknown_status
NCT02454530	Use of Biosimilar Nivestim® to Prevent Chemo-induced Neutropenia. Real Life Study	Filgrastim	Not Available	Not Available	terminated
NCT00776165	Safety and Efficacy Trial of Recombinant Human Granulocyte Colony Stimulating Factor (GCSF)	Filgrastim	prevention	3	completed
NCT04101760	Granulocyte Colony Stimulating Factor for for the Prevention of Febrile Neutropenia in Epithelial Ovarian Cancer	Filgrastim	treatment	3	unknown_status
NCT02700360	Evaluation of the Food Effect on the Safety, Tolerability, PK of EC-18 After Oral Administration in Healthy Volunteers	Mosedipimod	Not Available	1	completed
NCT04134429	Feasibility of Monitoring Health Data in Pediatric Patients Undergoing Chemotherapy	No drug interventions	Not Available	Not Available	completed
NCT02643901	Tolerability and Pharmacokinetics(PK)/Pharmacodynamics(PD) Study of GW003 in Healthy Subjects	No drug interventions	treatment	1	completed
NCT03251768	Recombinant Human Serum Albumin/Granulocyte Colony Stimulating Factor Fusion Protein for Breast Cancer Patients	Albumin human	treatment	2	completed
NCT04448314	Study to Evaluate the Usability of PointCheck	No drug interventions	Not Available	Not Available	completed
NCT03846414	Real World Study of PEG-rhG-CSF in Prevention of Chemotherapy-induced Neutropenia	No drug interventions	Not Available	Not Available	unknown_status
NCT03823950	Starting Granulocyte Colony-Stimulating Factor at 1 Day vs 3 Days Following Chemotherapy in Pediatric Cancer Patients	Filgrastim	supportive_care	4	unknown_status
NCT04460508	Mecapegfilgrastim(PEG-G-CSF) for Prophylaxis of Chemotherapy-induced Neutropenia in Patients With Lymphoma	Mecapegfilgrastim	prevention	2	unknown_status
NCT06649448	A Multi-cohort Study of Efbemalenograstim Alfa Injection for Preventing ANC Reduction in Solid Tumor Patients Post Immune-chemotherapy.	No drug interventions	prevention	Not Available	not_yet_recruiting
NCT01923545	Phase II Study of DA-3031(PEG-G-CSF) in Chemotherapy-induced Neutropenia	Filgrastim	treatment	2	completed
NCT02787876	Pegteograstim in Children With Solid Tumors	Pegteograstim	treatment	2	unknown_status
NCT01328938	GCPGC in Chemotherapy-induced Neutropenia	Pegfilgrastim	prevention	2 / 3	completed
NCT01674855	Phase III Study of DA-3031(PEG-G-CSF) in Chemotherapy-induced Neutropenia	Filgrastim	treatment	3	completed
NCT01519700	Phase III Study Comparing the Efficacy and Safety of EP2006 and Filgrastim	Filgrastim	supportive_care	3	completed