Hemophilia B With Inhibitors (DBCOND0067399)

Identifiers

Synonyms
Hemophilia B With Inhibitor / Haemophilia B With Inhibitors / Haemophilia B with inhibitor / Hereditary factor IX deficiency disease with inhibitor (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Coagulation factor VIIa Recombinant Human
A form of recombinant human coagulation Factor VII used to treat hemophilia A and B.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02448680
A Phase III Study on the Safety, Pharmacokinetics and Efficacy of Coagulation Factor VIIaNo drug interventionstreatment3completed
NCT02020369
Phase III Study of Coagulation FVIIa (Recombinant) in Congenital Hemophilia A or B Patients With Inhibitorstreatment3completed
NCT02484638
Study of Recombinant Factor VIIa Fusion Protein (rVIIa-FP, CSL689) for On-demand Treatment of Bleeding Episodes in Patients With Hemophilia A or B With Inhibitorstreatment2 / 3terminated
NCT06568302
The Long-term Safety and Efficacy of SerpinPC in Subjects with Hemophilia Who Completed a Sponsored SerpinPC Clinical Trialtreatment3recruiting
NCT04647227
SEVENFACT® for Bleeding Events in Hemophilia With Inhibitorstreatment4recruiting
NCT05789537
A Study of SerpinPC in Participants with Hemophilia B (HemB) with Inhibitorstreatment2recruiting
NCT06010953
SS109 and NovoSeven ® PK / PD Profile, and Preliminary Efficacy and Safety of SS109 on Demand TreatmentNo drug interventionstreatment1 / 2completed
NCT05651061
A Phase I of SS109 in Hemophilia A or and B With InhibitorsNo drug interventionstreatment1completed
NCT03372993
Prospective, Non-interventional Study to Evaluate Immunogenicity of AryoSevenNo drug interventionsNot AvailableNot Availablecompleted
NCT04489537
Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Hemophilia A or BNo drug interventionstreatment3terminated
NCT03818529
ATHN 8: Previously Untreated Patients (PUPs) Matter StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT04789954
Study on the Dose-response Relationship of Pharmacodynamic Parameters in Patients With Hemophilia With Inhibitorstreatment0completed
NCT03407651
Study of Coagulation Factor VIIa Variant Marzeptacog Alfa (Activated) in Adult Subjects With Hemophilia A and Btreatment2completed
NCT04072237
Study of Coagulation Faction VIIa Variant Marzeptacog Alfa (Activated) in Adult Subjects With HemophiliaNo drug interventionsdiagnostic1completed
NCT06312475
Efficacy and Safety of KN057 Prophylaxis in Patients With Haemophilia A or B With InhibitorsNo drug interventionstreatment3recruiting
NCT04768699
Study of Recombinant Human Coagulation Factor VIIa for Injection (FⅦa) in Patients With Hemophilia.treatment1unknown_status
NCT03619863
ATHN 7: Hemophilia Natural History StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00571584
High Dose of Activated Recombinant Human Factor VII for Treatment of Mild/Moderate Joint Bleeds in Haemophilia Patients With Inhibitorstreatment4completed
NCT03196284
A Trial Evaluating the Efficacy and Safety of Prophylactic Administration of Concizumab in Haemophilia A and B Patients With Inhibitorstreatment2completed
NCT00703911
Observational Registry of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With InhibitorsNot AvailableNot Availablecompleted
NCT01563471
Safety and Tolerability of Intravenous Doses of Activated Recombinant Human Factor VII in Healthy Volunteerstreatment1completed
NCT00882778
PROPACT: Retrospective Prophylaxis Patient Case CollectionNot AvailableNot Availablecompleted
NCT01988532
Impact of Pain on Functional Impairment and Quality of Life in Adults With HemophiliaNo drug interventionsNot AvailableNot Availablecompleted
NCT00710619
Observational Patient Diary Study of Treatment Doses for Patients With Haemophilia With Inhibitors to Factors VIII and IXNot AvailableNot Availablecompleted
NCT01561924
Prediction of the Efficacy of Activated Recombinant Human Factor VII in Adult Congenital Haemophilia A or B Patients With Inhibitors by Use of Thromboelastographydiagnostic1completed
NCT00108758
Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophiliatreatment2completed
NCT01561391
Safety and Efficacy of Activated Recombinant Human Factor VII in Haemophilia Patients With Inhibitors During and After Major Surgerytreatment4completed
NCT01949792
A Trial Investigating the Pharmacokinetics and Pharmacodynamics of rFVIIa in Patients With Haemophilia A or B With or Without Inhibitorstreatment1completed
NCT01503567
Epidemiological Study on Haemophilia Care and Orthopaedic Status in Developing CountriesNo drug interventionsNot AvailableNot Availablecompleted
NCT01579968
Non-Interventional Study of NovoSeven® Used in Patients With Haemophilia A and B With Inhibitors When Undergoing SurgeryNot AvailableNot Availablecompleted
NCT01830712
A Long-term Assessment of Physical Activity, Range of Motion, and Functional Status Following Elective Orthopedic Surgery in Hemophilia Patients With InhibitorsNot AvailableNot Availablecompleted
NCT04083781
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitorstreatment3active_not_recruiting
NCT03741881
A Study Following People With Haemophilia A and B, With or Without Inhibitors, When on Usual Treatment (Explorer™6)No drug interventionsNot AvailableNot Availablecompleted
NCT01579955
Non-Interventional Study of NovoSeven® Used in Patients With Haemophilia A and B With Inhibitors Under Normal Clinical PracticeNot AvailableNot Availablecompleted
NCT01392547
Efficacy and Safety of NNC 0078-0000-0007 in Patients With Congenital Haemophilia and Inhibitorstreatment3completed
NCT00951405
Safety and Efficacy of 3 Different Doses of Long Acting Factor VII in Haemophilia A or B Patients With Inhibitorsprevention2completed
NCT00108797
Trial of NovoSeven® in Haemophilia - Joint Bleedstreatment4completed
NCT02541942
Pharmacogenetic Testing of Saliva Samples From Patients With Five or More Exposure Days to rFVIIa Analogue in the Adept™2 TrialNo drug interventionsother2completed
NCT01586936
Non-Interventional Study of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With InhibitorsNot AvailableNot Availablecompleted
NCT01561417
Bioequivalence of NovoSeven® and a NovoSeven® Formulation Stable at Room Temperature in Healthy Male Subjectstreatment1completed
NCT01322620
Survey Evaluating the Psychosocial Effects of Living With HaemophiliaNo drug interventionsNot AvailableNot Availablecompleted
NCT02241694
To Quantify the Range of Main Psychosocial Factors Affecting Patients and Caregivers in Their Daily LivesNo drug interventionsNot AvailableNot Availablecompleted
NCT02084810
Investigating the Bioequivalence of Eptacog Alfa A 6 mg and NovoSeven® in Healthy Male Subjectstreatment1withdrawn