Antianginal Agents

Antianginal Agents
Accession Number
DBCAT002737  (DBCAT003304)

Not Available

DrugDrug Description
AmlodipineA calcium channel blocker used to treat hypertension and angina.
LefradafibanFor the treatment of unstable angina.
Alferminogene tadenovecInvestigated for use/treatment in angina, coronary artery disease, and heart disease.
RanolazineAn anti-anginal drug used for the treatment of chronic angina.
NitroglycerinA nitrate vasodilator used to treat or prevent angina, treat hypertension, control heart failure in myocardial infarction, and to induce hypotension intraoperatively.
Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
Erythrityl tetranitrateFor the prevention of angina.
Pentaerythritol tetranitrateUsed for the treatment of angina pectoris .
Propatyl nitrateNot Annotated
Methylpropylpropanediol dinitrateNot Annotated
TenitramineNot Annotated
TrolnitrateNot Annotated
IsosorbideA vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease. It was previously used to reduce intraocular pressure.
NitrateNot Annotated
Amyl NitriteA fast acting vasodilator used for rapid relief of angina pectoris.
Drugs & Drug Targets
AmlodipineCarbonic anhydrase 1target
AmlodipineCytochrome P450 3A4enzyme
AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
AmlodipineCytochrome P450 1A1enzyme
AmlodipineCytochrome P450 2B6enzyme
AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
AmlodipineCytochrome P450 3A5enzyme
AmlodipineP-glycoprotein 1transporter
AmlodipineCytochrome P450 2C8enzyme
AmlodipineCytochrome P450 2D6enzyme
AmlodipineSphingomyelin phosphodiesterasetarget
AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmlodipineVoltage-dependent N-type calcium channeltarget
LefradafibanIntegrin alpha-IIbtarget
LefradafibanIntegrin beta-3target
RanolazineCytochrome P450 3A4enzyme
RanolazineCytochrome P450 2D6enzyme
RanolazineBile salt export pumptransporter
RanolazineP-glycoprotein 1transporter
RanolazineSodium channel proteintarget
RanolazineInward rectifier potassium channeltarget
RanolazineVoltage gated L-type calcium channeltarget
RanolazineAlpha-1 adrenergic receptorstarget
RanolazineBeta-1 adrenergic receptortarget
RanolazineFatty acidtarget
RanolazineAlpha-1-acid glycoprotein 1carrier
RanolazineMultidrug and toxin extrusion protein 1transporter
RanolazineMultidrug and toxin extrusion protein 2transporter
NitroglycerinAtrial natriuretic peptide receptor 1target
NitroglycerinAldehyde dehydrogenase, mitochondrialenzyme
Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
Isosorbide dinitrateCytochrome P450 2E1enzyme
Isosorbide mononitrateGuanylate cyclase soluble subunit alpha-2target
Isosorbide mononitrateGlutathione S-transferase Mu 1enzyme
Isosorbide mononitrateXanthine dehydrogenase/oxidaseenzyme
Isosorbide mononitrateAlcohol dehydrogenase class-3enzyme
Erythrityl tetranitrateAtrial natriuretic peptide receptor 1target
Erythrityl tetranitrateAtrial natriuretic peptide receptor 2target
Pentaerythritol tetranitrateHemoglobin subunit alphatarget
Pentaerythritol tetranitrateHemoglobin subunit betatarget
Pentaerythritol tetranitrateGuanylate cyclase soluble subunit alpha-2enzyme
Pentaerythritol tetranitrateFree radicalstarget
Pentaerythritol tetranitrateNitric oxide synthase, endothelialenzyme
Pentaerythritol tetranitrateAldehyde dehydrogenase, mitochondrialenzyme
IsosorbideGuanylate cyclasetarget
Amyl NitriteAtrial natriuretic peptide receptor 1target
Amyl NitriteAldehyde dehydrogenase, mitochondrialenzyme