Monoamine Oxidase Inhibitors
- Name
- Monoamine Oxidase Inhibitors
- Accession Number
- DBCAT001004 (DBCAT002868)
- Description
A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414)
- ATC Classification
- Drugs
Drug Drug Description Tranylcypromine A monoamine oxidase inhibitor used to treat major depressive disorder. Phenelzine A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression. Selegiline A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. Moclobemide A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. Isocarboxazid A monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs. Rasagiline An irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa. Pargyline For the treatment of moderate to severe hypertension. Minaprine For the treatment of depression Iproniazid For the treatment of depression (originally intended to treat tuberculosis). Nialamide Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine. Pirlindole For the treatment of major depression. It is being studied in the treatment of fibromyalgia pain syndrome. One study determined that the effect of pirlindole on sensorimotor performance while driving... Toloxatone For the treatment of major depressive disorder. Hydracarbazine Was used for the treatment of hypertension . Methylene blue An oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia. Benmoxin For the treatment of depression. Mebanazine For the treatment of depression. Octamoxin For the treatment of depression. Pheniprazine For the treatment of depression, schizophrenia, and angina pectoris. Phenoxypropazine For the treatment of depression. Pivhydrazine For the treatment of depression. Safrazine For the treatment of depression. Caroxazone For the treatment of depression. Furazolidone A drug for the treatment of infectious diarrhea. 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline Potent reversible inhibitor of phenylethanolamine N-methyltransferase. Harmaline Not Annotated Brofaromine Not Annotated Procaine A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block. Procarbazine An antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents. Linezolid An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. Safinamide A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes. Clorgiline An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE. Harmine Not Available Viloxazine A selective norepinephrine reuptake inhibitor indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults in children. - Drugs & Drug Targets