NCT04598243
Treatment of Fibromyalgia and CFS With Ribose, Ashwagandha, Rhodiola, Licorice, Schisandra and Green Tea Extract No drug interventions treatment 0 unknown_status NCT04599348
Treatment of CFS and Fibromyalgia With HRG 80 Red Ginseng No drug interventions treatment 0 unknown_status NCT04877028
Frailty Screening in the Swedish Emergency Department Setting No drug interventions Not Available Not Available completed NCT03952624
Patient-Centered Assessment of Symptoms and Outcomes No drug interventions Not Available Not Available recruiting NCT06117462
Frailty in Critical Care Unit's Patients No drug interventions Not Available Not Available not_yet_recruiting NCT05229640
Relationship Between the Development of Impaired Glucose Tolerance, the Phenotype of CFLD, and the Risk of Liver Fibrosis No drug interventions diagnostic Not Available withdrawn NCT01055847
Aztreonam for Inhalation (AI) in Patients With Cystic Fibrosis & P. Aeruginosa Infection No drug interventions treatment 2 completed NCT00391703
Assessment of Quadriceps Muscle Electrostimulation Used in Patients Suffering From Cystic Fibrosis No drug interventions Not Available Not Available terminated NCT04625829
Anthropological Survey on the Use of Essential Oils (EOs) by Cystic Fibrosis Patients: a Quantitative and Qualitative Approach No drug interventions Not Available Not Available unknown_status NCT00834054
Measurement of Lung Water by Transpulmonary Thermodilution in Lung Transplanted Patients No drug interventions Not Available Not Available completed NCT03653377
Human Papilloma Virus Vaccination in Girls With Cystic Fibrosis (VACCIN-HPV-MUC2) No drug interventions Not Available Not Available completed NCT04225962
Intimacy of Women With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00356629
Development of a Noninvasive Method of Evaluation of Pulmonary Inflammation in the Condensates of Exhaled Air No drug interventions Not Available Not Available terminated NCT02036879
Gender Disparity and Hormones in Cystic Fibrosis No drug interventions basic_science 0 completed NCT01951833
Long Term Significance (Survival) of LCI in Patients With Cystic Fibrosis No drug interventions Not Available Not Available withdrawn NCT03597347
Trial of Inhaled Molgramostim in Cystic Fibrosis Subjects With Nontuberculous Mycobacterial Infection No drug interventions treatment 2 terminated NCT03445793
: TRANSITION: An Observational Study of Transition From Lumacaftor/Ivacaftor to Tezacaftor/Ivacaftor (Tez/Iva) No drug interventions Not Available Not Available completed NCT04375878
OPTION 2: A Trial to Assess the Safety and Efficacy of MS1819 in Enteric Capsules in Patients With Cystic Fibrosis No drug interventions treatment 2 completed NCT05818319
Cystic Fibrosis in the Kidney: Monitoring the Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in Urine After a Short Pause of Therapy No drug interventions diagnostic Not Available recruiting NCT00677365
Safety, Tolerability and Efficacy of MP-376 Given for 28 Days to Cystic Fibrosis (CF) Patients No drug interventions treatment 2 completed NCT04853368
Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/Navocaftor/ABBV-119 or Galicaftor/Navocaftor/ABBV-576 Combination Therapies in Adult Participants With Cystic Fibrosis No drug interventions treatment 2 terminated NCT02163681
MRI for Non-Invasive Imaging in Neonates and Children No drug interventions basic_science Not Available completed NCT02778750
Evaluation Of The Pan-microbiome and Host Immune Response in CF No drug interventions Not Available Not Available completed NCT02605590
Safety, Tolerability and Pharmacokinetics Study of AIR DNAse Administered by Inhalation to Healthy Adult Volunteers No drug interventions treatment 1 completed NCT03234387
A CFit Study - Baseline No drug interventions Not Available Not Available terminated NCT03746483
OPTION: A Trial to Assess the Safety & Efficacy of MS1819 in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis No drug interventions treatment 2 completed NCT01851642
Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs No drug interventions Not Available Not Available recruiting NCT01695343
Study to Evaluate the Effect of KB001-A on Time-to-Need for Antibiotic Treatment No drug interventions treatment 2 completed NCT05271643
Pilot Study of a CF-specific CBT Intervention for Adolescents No drug interventions treatment Not Available active_not_recruiting NCT00360503
Antimicrobial Resistance in Cystic Fibrosis (CF) No drug interventions Not Available Not Available completed NCT02129803
Evaluating High Flow Humidification Therapy in Patients With Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT02038803
Efficacy of TOBI Podhaler vs. Tobramycin Inhalation Solution No drug interventions Not Available Not Available completed NCT00625703
Pharmacokinetics of Linezolid in Children With Cystic Fibrosis No drug interventions other 2 completed NCT04680403
Video Telehealth Exercise Training in Cystic Fibrosis No drug interventions prevention Not Available recruiting NCT00528190
Treatment of Aspergillus Fumigatus (a Fungal Infection) in Patients With Cystic Fibrosis No drug interventions prevention 4 completed NCT04183790
Evaluation of Long-term Safety and Efficacy of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Who Are 6 Years of Age and Older No drug interventions treatment 3 completed NCT05292690
An Assistive Powered Wheelchair: Stage 2 Trial No drug interventions Not Available Not Available completed NCT00541190
Absorptive Clearance in the Cystic Fibrosis Airway No drug interventions basic_science Not Available completed NCT02682290
Assessment of Rheological Parameters of Human Sputum. No drug interventions other Not Available completed NCT03460990
A Study of VX-659 Combination Therapy in CF Subjects Homozygous for F508del (F/F) No drug interventions treatment 3 completed NCT03652090
Primary Nasal Cell Culture as a Tool for Personalized Therapy in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01943890
High Volumes of Hypertonic Saline and Chest Physiotherapy in CF Patients No drug interventions treatment Not Available completed NCT02690064
Mechanisms for Vascular Dysfunction and Exercise Tolerance in CF No drug interventions treatment Not Available active_not_recruiting NCT01257464
Sitagliptin in Cystic Fibrosis-Related Diabetes No drug interventions treatment 2 terminated NCT05314764
Cefiderocol Pharmacokinetics in Adult Patients With Cystic Fibrosis No drug interventions other 4 recruiting NCT03117764
1STST and Muscle Weakness in CF Patients No drug interventions treatment Not Available completed NCT02363764
The Challenge of Obtaining Qualitative Bacterial Cultures in Non-expectorating Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT02532764
Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients No drug interventions treatment 1 / 2 completed NCT02342964
Comparison of Non-invasive Measurement Methods of Hepatic Fibrosis in Cystic Fibrosis No drug interventions screening Not Available completed NCT06512064
Acoustic Waveform Respiratory Evaluation No drug interventions diagnostic Not Available not_yet_recruiting NCT03219164
Study of Aztreonam for Inhalation in Children With Cystic Fibrosis and New Infection of the Airways by Pseudomonas Aeruginosa Bacteria No drug interventions treatment 3 terminated NCT00457821
Safety Study of Ivacaftor in Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT01072721
Non Invasive Study of the Hepatic Fibrosis in Paediatrics by the Method of Study of Pediatric Hepatic Fibrosis No drug interventions diagnostic Not Available completed NCT02029521
Supplementation of Oral Reduced Glutathione in Pediatric Cystic Fibrosis Patients No drug interventions treatment Not Available completed NCT01093521
A Pharmacokinetic and Safety Study of IV Gallium Nitrate (Ganite) in Cystic Fibrosis Patients No drug interventions other 1 completed NCT05377502
Performance and Patient Acceptance of a Commercially Available Beverage as Compared to an Oral Glucose Solution for Oral Glucose Tolerance Tests in Cystic Fibrosis (CF) Patients Who Are Screened for CF-related Diabetes. No drug interventions Not Available Not Available unknown_status NCT03335202
Longitudinal Analysis of Respiratory and Intestinal Microbiome in Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT00363402
18FDG- PET/CT Contribution to the Assessment of Lesion Severity in Cystic Fibrosis (CF) No drug interventions diagnostic Not Available completed NCT01104402
Early Intervention in Cystic Fibrosis Exacerbation No drug interventions treatment Not Available completed NCT02203084
Social Determinants in Chronic Disease in British Columbia No drug interventions Not Available Not Available completed NCT05217784
COVID-19 Antibody Responses in Cystic Fibrosis (CAR-CF) No drug interventions Not Available Not Available unknown_status NCT06012084
The Development and Evaluation of iCF-PWR for Healthy Siblings of Individuals With Cystic Fibrosis No drug interventions prevention Not Available recruiting NCT01615484
Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability No drug interventions treatment Not Available completed NCT02894684
Aztreonam for Inhalation Solution (AZLI) for the Treatment of Exacerbations of Cystic Fibrosis No drug interventions treatment 4 completed NCT03375684
Effects of Inspiratory Muscle Training on Postural Stability, Balance, Pulmonary Function and Functional Capacity in Children With Cystic Fibrosis No drug interventions treatment Not Available completed NCT02305784
Kinetics of YKL-40 Protein in Serum of Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT00510484
Study Investigating a Delayed-Release Pancrelipase in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis No drug interventions treatment 3 completed NCT02128984
Clinical Study With an Enteral Formula With Symbiotic and DHA for Malnourished Children No drug interventions treatment Not Available completed NCT01883284
Action of Epigenetic Modifiers in Cystic Fibrosis Treatment No drug interventions basic_science Not Available completed NCT01293084
Hypertonic Saline and Mucociliary Clearance in Children No drug interventions treatment 2 completed NCT00800579
Trial to Assess the Safety, Tolerability and Pharmacokinetics of GS-9411 in Healthy Male Volunteers No drug interventions treatment 1 completed NCT01306279
The Infective Pulmonary Exacerbations in Cystic Fibrosis - an Ecological Perspective No drug interventions Not Available Not Available completed NCT02265679
Safety, Tolerability and Pharmacokinetics of Increasing Doses of BIIL 284 BS in Adult and Pediatric Cystic Fibrosis (CF) Patients No drug interventions treatment 1 completed NCT00357279
Study of Denufosol Inhalation Solution in Patients With Mild Cystic Fibrosis Lung Disease No drug interventions treatment 3 completed NCT00670579
Study About Complications of Totally Implanted Venous Access Devices (TIVADs) in People With Cystic Fibrosis (CF) No drug interventions Not Available Not Available completed NCT02858843
The Effect of Combination Lumacaftor and Ivacaftor on Markers of Hyperglycemia No drug interventions screening Not Available terminated NCT04039087
Sildenafil Exercise: Role of PDE5 Inhibition No drug interventions supportive_care 2 / 3 unknown_status NCT06312787
A Study to Evaluate the Relative Bioavailability and Food Effect of a VX-118 Tablet Formulation No drug interventions treatment 1 completed NCT02261987
Resistive Inspiratory Manoeuvre as Airway Clearance Technique in Cystic Fibrosis No drug interventions treatment Not Available completed NCT05501587
Measures of Respiratory Health Registry No drug interventions Not Available Not Available recruiting NCT00753987
Tolerability of Hypertonic Saline in Infants With Cystic Fibrosis No drug interventions treatment 1 completed NCT00840333
"Safety, Tolerability and Pharmacokinetics of MP-376 Administered for 14 Days to Stable Pediatric (CF) Patients" No drug interventions treatment 1 completed NCT04940533
Pharmacokinetics of CFTR Modulators in Pregnant Individuals and in Postpartum Breastfeeding Mothers No drug interventions Not Available Not Available not_yet_recruiting NCT03912233
A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT01897233
Study of Lumacaftor in Combination With Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation No drug interventions treatment 3 completed NCT01253733
MD2Me - Texting to Promote Chronic Disease Management No drug interventions supportive_care Not Available completed NCT02564354
Exploratory Study to Evaluate QR-010 in Subjects With Cystic Fibrosis ΔF508 CFTR Mutation No drug interventions treatment 1 completed NCT02378454
Multiple Breath Nitrogen Washout in Healthy and Cystic Fibrosis Children No drug interventions Not Available Not Available completed NCT01812551
Treatment of Low Bone Density in Cystic Fibrosis. No drug interventions treatment 3 completed NCT02649751
Evaluation of (R)-Roscovitine Safety and Effects in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation No drug interventions treatment 2 terminated NCT01140451
Extension Study of Ataluren (PTC124) in Cystic Fibrosis No drug interventions treatment 3 completed NCT06457451
Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adults With Cystic Fibrosis Treated With Elexacaftor-Tezacaftor-Ivacaftor: Multicentre Randomised Controlled Trial No drug interventions supportive_care Not Available not_yet_recruiting NCT00850551
Early Intervention in Pulmonary Exacerbation in Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT02544451
Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Lumacaftor in Combination With Ivacaftor No drug interventions treatment 3 completed NCT03537651
A Study to Evaluate the Safety and Efficacy of Long-term Treatment With TEZ/IVA in CF Participants With an F508del CFTR Mutation No drug interventions treatment 3 completed NCT01923753
A Short-term Comparative Study of Aerosure for Airway Clearance in Patients With Cystic Fibrosis No drug interventions treatment 2 terminated NCT00547053
Amiloride Solution and Tobramycin Solution for Inhalation for the Eradication of Burkholderia Dolosa in Patients With Cystic Fibrosis No drug interventions treatment 1 completed NCT06020547
Cystic Fibrosis and Frailtyh What's in Common? No drug interventions Not Available Not Available completed NCT00817947
Airway Clearance Using High Frequency Chest Wall Oscillation No drug interventions treatment 3 completed NCT03375047
Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis No drug interventions treatment 1 / 2 unknown_status NCT00945347
Does a Nasal Instillation of Miglustat Normalize the Nasal Potential Difference in Cystic Fibrosis Patients ? No drug interventions treatment 2 completed NCT05088447
A Study to Investigate Cystic Fibrosis Pulmonary Exacerbations and the Lung Microbiome No drug interventions Not Available Not Available terminated NCT01179347
Tiotropium Bromide in Cystic Fibrosis No drug interventions treatment 3 completed NCT03924947
A Study to Compare US Marketed Creon Manufactured With a Modernized Process at an Alternate Manufacturing Site and Manufactured With the Approved Manufacturing Process at an Alternate Active Pharmaceutical Ingredient Site, in Participants With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis No drug interventions treatment 4 completed NCT02423447
Comparison of the Airway Clearance Efficacy of Electro Flo 5000 and the G5 Flimm-Fighter in Patients With CF No drug interventions health_services_research Not Available completed NCT01270347
Trial of Aeroquin Versus Tobramycin Inhalation Solution (TIS) in Cystic Fibrosis (CF) Patients No drug interventions treatment 3 completed NCT06154447
A Phase 1, First-in-human Study of VX-828 treatment 1 recruiting NCT00004747
Phase II Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Mucoid Exopolysaccharide Pseudomonas Aeruginosa Immune Globulin for Cystic Fibrosis No drug interventions treatment 2 completed NCT05111145
A Study Evaluating the Safety of Elexacaftor/Tezacaftor/Ivacaftor in Participants With Cystic Fibrosis (CF) treatment 3 completed NCT04904445
COVID-19 Antibody Responses In Cystic Fibrosis No drug interventions Not Available Not Available active_not_recruiting NCT00589745
Nasal Potential Difference (NPD) for the Diagnosis of Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT00177645
Inhaled Bicarbonate Therapy in Cystic Fibrosis No drug interventions basic_science 1 completed NCT01207245
Circadian Rhythm In Tobramycin Elimination In Cystic Fibrosis No drug interventions treatment 4 completed NCT00016445
Phase II Study of Growth Hormone in Children With Cystic Fibrosis treatment 2 completed NCT03451045
Trial to Evaluate Efficacy and Safety of Lenabasum in Cystic Fibrosis No drug interventions treatment 2 completed NCT05641298
Study to Determine the Efficacy&Safety of ARV-1801(ACG-701) for the Treatment of Cystic Fibrosis Pulmonary Exacerbations treatment 2 withdrawn NCT00967798
Prevention of Cystic Fibrosis Diabetes No drug interventions prevention 3 terminated NCT00179998
Effectiveness of Pulmozyme in Infants With Cystic Fibrosis treatment 2 completed NCT02776098
Muscle Accrual and Function in Cystic Fibrosis-Impact of Glucose Intolerance No drug interventions Not Available Not Available completed NCT02276898
A Randomized-Controlled Trial of Inhaled Hypertonic Saline (7%) to Evaluate the Lung Clearance Index No drug interventions treatment 2 completed NCT02721498
Improving Outcome Measures For Adult CF ACT Trials No drug interventions other Not Available completed NCT01321905
Prospective Intervention Study on Vitamin D in Patients With Cystic Fibrosis No drug interventions treatment 2 unknown_status NCT01149005
Cystic Fibrosis (CF) Exacerbation and Insulin Treatment No drug interventions treatment Not Available unknown_status NCT00803205
Study of Ataluren (PTC124™) in Cystic Fibrosis No drug interventions treatment 3 completed NCT00388505
Safety of Tobramycin Inhalation Powder (TIP) vs Tobramycin Solution for Inhalation in Patients With Cystic Fibrosis No drug interventions treatment 3 completed NCT04254705
Organoid Study R334W No drug interventions other Not Available withdrawn NCT06222905
Analysis of Remote Monitoring/Virtual Clinic Data in Adult Patients With Cystic Fibrosis (Project Breathe) No drug interventions Not Available Not Available recruiting NCT04589897
Manuka Honey Sinus Rinse Study No drug interventions basic_science Not Available completed NCT04966897
Assessment of a PERT-free Nutritional Therapeutic Delivery System for Cystic Fibrosis No drug interventions treatment Not Available completed NCT05069597
Study to Evaluate Symptoms of Exocrine Pancreatic Insufficiency in Adult Participants With Cystic Fibrosis or Chronic Pancreatitis Treated With Creon treatment 4 completed NCT05206097
Determinants of Daily Physical Activity Level in Patients With Cystic Fibrosis - Pilot Study Protocol No drug interventions other Not Available unknown_status NCT01887197
Repeatability and Response Study of Absorptive Clearance Scans No drug interventions basic_science 1 completed NCT05331183
Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del treatment 3 active_not_recruiting NCT00105183
EZ-2053 in the Prophylaxis of Acute Pulmonary Allograft Rejection No drug interventions prevention 3 completed NCT02398383
Role of Glucagon In Glucose Control in Cystic Fibrosis Related Diabetes No drug interventions basic_science 0 completed NCT03052283
Development and Validation of a Disease Specific PROM to Assess Abdominal Involvement in Patients With CF (CFAbd-Score) No drug interventions Not Available Not Available recruiting NCT00804583
Genetic Modifiers of Cystic Fibrosis (CF) Liver Disease No drug interventions Not Available Not Available active_not_recruiting NCT05548283
Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study No drug interventions treatment 4 recruiting NCT04171583
Mucoid Staphylococcus Aureus in Cystic Fibrosis Airways No drug interventions Not Available Not Available completed NCT04530383
Effects of Metformin on Airway Ion Channel Dysfunction in Cystic Fibrosis-related Diabetes No drug interventions treatment 2 recruiting NCT00605761
SD Cystic Fibrosis Study No drug interventions treatment 1 completed NCT00504361
Blood Collection From Individuals With Lung Disease for Genetic Studies (Qatar) No drug interventions Not Available Not Available completed NCT01744561
Effects of a Partially Supervised Conditioning Program in CF No drug interventions treatment Not Available completed NCT03506061
Trikafta in Cystic Fibrosis Patients No drug interventions treatment 2 completed NCT00686361
Choline Nutrition in Children With Cystic Fibrosis (CF) No drug interventions treatment Not Available completed NCT00432861
Evaluation of the Safety and Efficacy of Pancrecarb® MS-16 in Cystic Fibrosis No drug interventions treatment 3 completed NCT01961661
Probiotics on Intestinal Inflammation in Cystic Fibrosis No drug interventions prevention 3 completed NCT00775528
Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis No drug interventions treatment 3 completed NCT01586728
Oxygen Therapy in Cystic Fibrosis No drug interventions treatment Not Available terminated NCT03350828
CHaractErizing CFTR Modulated Changes in Sweat Chloride and Their Association With Clinical Outcomes No drug interventions Not Available Not Available active_not_recruiting NCT00376428
Interest of Gentamicin-induced Readthrough in Cystic Fibrosis Patients No drug interventions treatment 2 terminated NCT04176328
Open-label, Dose-escalation Study to Evaluate the Pharmacokinetics of Inhaled Teicoplanin in Cystic Fibrosis Patients No drug interventions treatment 1 completed NCT03318328
Evaluation of Food Insecurity in Adults and Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01468428
Small Intestinal Function in Patients With Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT01879228
Effect of Chronic Incretin-based Therapy in Cystic Fibrosis No drug interventions other Not Available completed NCT00381628
Nasal Epithelial Cells/Blood Lymphocyte Markers for Cystic Fibrosis (CF)/CF Pulmonary Exacerbations No drug interventions Not Available Not Available completed NCT05239611
Feasibility of Home-based Exercise Program for Adults With Cystic Fibrosis No drug interventions treatment 2 completed NCT04579211
Prospective Analysis of Urine LAM to Eliminate NTM Sputum Screening No drug interventions Not Available Not Available enrolling_by_invitation NCT02010411
Alpha1 Antitrypsin Aerosol Therapy in Cystic Fibrosis No drug interventions treatment 2 terminated NCT02128711
Mapping Chemical and Microbiological Heterogeneity Throughout Explanted Cystic Fibrosis Lung Specimens No drug interventions Not Available Not Available recruiting NCT02412111
A Phase 3 Study of Tezacaftor (VX-661) in Combination With Ivacaftor (VX-770) in Subjects Aged 12 Years and Older With Cystic Fibrosis (CF), Who Have One F508del-CFTR Mutation and a Second Mutation That Has Been Demonstrated to be Clinically Responsive to Ivacaftor No drug interventions treatment 3 completed NCT02562911
Puberty in Girls Followed for Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03172793
Telavancin Pharmacokinetics in Cystic Fibrosis Patients No drug interventions other 4 completed NCT02694393
Inhaled Sodium Nitrite as an Antimicrobial for Cystic Fibrosis No drug interventions treatment 1 / 2 terminated NCT06149793
SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes treatment 2 / 3 recruiting NCT06339593
Regional Monitoring of CF Lung Disease No drug interventions Not Available Not Available recruiting NCT02730793
Aztreonam Aerosol to Treat Cystic Fibrosis Nasal Disease No drug interventions treatment 2 terminated NCT04537793
Evaluation of ELX/TEZ/IVA in Cystic Fibrosis (CF) Subjects 2 Through 5 Years No drug interventions treatment 3 completed NCT04644471
Comparison Between Ultra-low-dose Computed Tomography and Lung MRI in Cystic Fibrosis No drug interventions diagnostic Not Available recruiting NCT01987271
Effects Of Noninvasive Ventilation On Functional Capacity Of Patients With Cystic Fibrosis No drug interventions treatment Not Available completed NCT00004471
Phase I Pilot Study of Gene Therapy for Cystic Fibrosis Using Cationic Liposome Mediated Gene Transfer No drug interventions treatment 1 completed NCT03227471
A Study of VX-445 in Healthy Subjects and Subjects With Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT02262871
HFN Versus NIV in Cystic Fibrosis. The HIFEN Study No drug interventions treatment Not Available completed NCT02148978
Cystic Fibrosis Related Diabetes No drug interventions supportive_care Not Available unknown_status NCT00037778
Genetic Modifiers of Cystic Fibrosis: Sibling Study No drug interventions Not Available Not Available completed NCT00449878
Liprotamase Efficacy Trial in Patients With Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency No drug interventions treatment 3 completed NCT06147778
Performances and Safety of MuCopilot, a Digital Tool for the Unsupervised Objective Assessment of Cystic Fibrosis No drug interventions other Not Available not_yet_recruiting NCT00434278
A Trial of Pulmozyme Withdrawal on Exercise Tolerance in Cystic Fibrosis Subjects With Severe Lung Disease (TOPIC) No drug interventions treatment 4 terminated NCT05453578
A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa No drug interventions treatment 1 / 2 recruiting NCT03754088
In Vitro Model of the Cystic Fibrosis Bronchial Epithelium Via iPS Technology No drug interventions Not Available Not Available completed NCT03078088
Airway Alkalinization and Nasal Colonization No drug interventions prevention 1 completed NCT00506688
Efficacy and Safety Study of Inhaled Glutathione in Cystic Fibrosis Patients No drug interventions treatment 2 completed NCT03873688
Effects of Expiratory Muscle Training on Cough Efficacy in Children and Adolescents With Cystic Fibrosis No drug interventions treatment Not Available completed NCT03265288
Study of LAU-7b in the Treatment of Cystic Fibrosis in Adults No drug interventions treatment 2 completed NCT02015507
An Open-Label, Phase 1 Study in Healthy Adult Subjects to Examine the Effects of Multiple-Dose Ciprofloxacin on Ivacaftor and VX-661 in Combination With Ivacaftor No drug interventions treatment 1 completed NCT01877707
Near Patient Microbial Testing in Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT04809207
Acceptability, Feasibility and Preliminary Efficacy of CFWP to Treat Clinically Elevated Fatigue in Adults With CF No drug interventions treatment Not Available completed NCT00989807
Expanded Access Program for Aztreonam Lysine for Inhalation in Canadian Patients With Cystic Fibrosis No drug interventions Not Available Not Available approved_for_marketing NCT02508207
A Phase 2 Study to Evaluate Effects of VX-661/Ivacaftor on Lung and Extrapulmonary Systems in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation No drug interventions treatment 2 completed NCT01494909
Development Of An Innovative Panel of Methods To Measure Intestinal Macronutrient Digestion, Absorption, and Function No drug interventions other Not Available unknown_status NCT00730509
Effects of 5-Methyltetrahydrofolate and Vitamin B12 Supplemetation on Red Cell Membrane in Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03782909
Evaluation of a Behavioural Intervention Using App Technology in CF No drug interventions health_services_research Not Available completed NCT04683809
Effects of a Telerehabilitation Approach in Children With Cystic Fibrosis No drug interventions supportive_care Not Available unknown_status NCT06299709
A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulation of Vanzacaftor/Tezacaftor/Deutivacaftor(VNZ/TEZ/D-IVA) treatment 1 completed NCT06507956
Physical Activity Profile and Sedentary Behaviour in Adults With Cystic Fibrosis No drug interventions Not Available Not Available not_yet_recruiting NCT02847156
Impact of Respiratory Viral Infections in Infants With Cystic Fibrosis. No drug interventions Not Available Not Available completed NCT02054156
OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis No drug interventions treatment 3 completed NCT01426256
Vitamin D for Enhancing the Immune System in Cystic Fibrosis (DISC Study) No drug interventions treatment 3 completed NCT03577756
Neurodevelopmental Assessment of Infants With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03052556
Human Papillomavirus and Cervical Dysplasia in Women With Cystic Fibrosis No drug interventions screening Not Available completed NCT04618185
Gut Imaging for Function & Transit in CF - GIFT-CF 3 No drug interventions Not Available Not Available completed NCT03298685
SAFETIM-needs : Exploring Adolescent's and Parent's Needs During Transition in French CF Centers No drug interventions Not Available Not Available completed NCT03390985
Canadian Observation Trial in CF Patients Undergoing Treatment With Ivacaftor No drug interventions Not Available Not Available completed NCT04892485
Relationship of Skeletal Muscle Thickness, Strength, and Diaphragm Function in Adults With CF No drug interventions Not Available Not Available completed NCT00727285
Cystic Fibrosis (CF) Leukocyte Genes as Biomarkers for Novel Therapies No drug interventions Not Available Not Available completed NCT01729585
The Effects of Massage Therapy on QOL in Youth/Young Adults With Cystic Fibrosis No drug interventions treatment Not Available completed NCT06088485
The Effect of Bone Mineral Density in Patients With Adult Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT06063785
Multispectral Optoacoustic Tomography in Patients With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT05147285
The Effect of Telerehabilitation on Functional Capacity, Oxidative Stress and Respiratory Parameters in Cystic Fibrosis No drug interventions treatment Not Available completed NCT00332215
A Phase I Study of Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. No drug interventions treatment 1 terminated NCT02807415
ICM to Evaluate the Activation of p.Phe508del-CFTR by Lumacaftor in Combination With Ivacaftor No drug interventions Not Available Not Available completed NCT00004315
Phase II Pilot Study to Compare the Bioavailability of Buffered, Enteric-Coated Ursodiol With Unmodified Ursodiol for Chronic Cholestatic Liver Disease and Cystic Fibrosis-Associated Liver Disease treatment 2 unknown_status NCT01161537
Study of the Effect of VX-770 on Hyperpolarized Helium-3 Magnetic Resonance Imaging in Subjects With Cystic Fibrosis and the G551D Mutation No drug interventions treatment 2 completed NCT01883037
Comparing Laboratory Blood Glucose Results With HemoCue Glucose 201 RT No drug interventions Not Available Not Available completed NCT02657837
Measures of Respiratory Health (MRH) No drug interventions Not Available Not Available recruiting NCT05686837
Prospective Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria No drug interventions Not Available Not Available enrolling_by_invitation NCT00486837
Deposition of Inhaled Prolastin in Cystic Fibrosis Patients No drug interventions treatment 2 completed NCT02056132
Breath Condensate Study in Patients With Cystic Fibrosis. No drug interventions Not Available Not Available completed NCT06565832
Reproducibility of Virtual Exercise Assessments Versus Face-to-face Exercise Testing in Adults With Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT03965832
HFNT During Exercise in CF No drug interventions other Not Available completed NCT00909532
Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older With the G551D Mutation No drug interventions treatment 3 completed NCT04921332
Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD No drug interventions supportive_care Not Available terminated NCT02869932
Prospective Study of the Phenotypic Expression of Cystic Fibrosis (CF) Screened Positive Newborns With an Atypical Form of CF (DPAM) No drug interventions other Not Available completed NCT04341532
Bacterial Gene Profiling to Predict Antibiotic Resistance During Cystic Fibrosis Pulmonary Exacerbations No drug interventions Not Available Not Available recruiting NCT02797132
Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del No drug interventions treatment 3 completed NCT00095732
Oral TheraCLEC™ - Total in Cystic Fibrosis Subjects With Exocrine Pancreatic Insufficiency treatment 2 completed NCT02684552
Non Invasive Ventilation During Physical Training in Cystic Fibrosis No drug interventions treatment Not Available completed NCT03424252
An Phase 1 Study to Evaluate the Pharmacokinetic (PK) Profile of FDL169 New Formulations in Healthy Subjects No drug interventions treatment 1 completed NCT01262352
Study of the Effect of Ivacaftor on Lung Clearance Index in Subjects With Cystic Fibrosis and the G551D Mutation No drug interventions treatment 2 completed NCT04353752
Observational Trial of the Longitudinal Effects of CFTR Modulator Drugs No drug interventions Not Available Not Available active_not_recruiting NCT05727852
Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases No drug interventions Not Available Not Available enrolling_by_invitation NCT03229252
An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT02061852
Evaluation of the Safety of the Medical Device Simeox® No drug interventions treatment Not Available terminated NCT01599052
Social Cognition in Children Treated for a Brain Tumour No drug interventions Not Available Not Available completed NCT01155752
Pulmozyme in Cystic Fibrosis With Sinusitis No drug interventions treatment 3 withdrawn NCT06331000
Effect of One Year Elexacaftor-tezacaftor-ivacaftor Treatment Not Available Not Available not_yet_recruiting NCT03285100
The Effects of Discontinuation of Vitamin K Antagonists on the Rate of Elastin Degradation No drug interventions Not Available Not Available unknown_status NCT04468100
Efficacy and Safety of Tigerase® vs. Pulmozyme® in Patients With Cystic Fibrosis No drug interventions treatment 3 completed NCT03993600
New Markers of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function in Sweat No drug interventions diagnostic Not Available unknown_status NCT00880100
Use of Ultrase® MT12 in Young Cystic Fibrosis Children (CF) No drug interventions treatment 3 completed NCT01882400
Assessment of Response to Treatment of Osteoporosis With Oral Bisphosphonates in Patients With Muscular Dystrophy No drug interventions prevention 4 completed NCT00112359
International Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Cystic Fibrosis Patients With P. Aeruginosa No drug interventions treatment 3 completed NCT03684759
Sputum Validation for the Molecular Diagnosis of Respiratory Viral Infections in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00220259
Cystic Fibrosis Withdrawal of Inhaled Steroids Evaluation Study (CF WISE Study) No drug interventions prevention Not Available completed NCT01975259
Investigating the Incretin Effect in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00788359
Cystic Fibrosis Foundation (CFF) Biomarkers of Exacerbation No drug interventions Not Available Not Available completed NCT01112059
Trial of Doxycycline to Reduce Sputum MMP-9 Activity in Adult Cystic Fibrosis (CF) Patients No drug interventions treatment Not Available completed NCT04017559
Clinical Impact of MI on Inhaled Antibiotic Adherence in Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT03800459
Effect of a Family Empowerment Program on Coping, Problem Solving in Parents, and Quality of Life in Children With Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT00404859
FLAME: Airway Inflammation Monitoring in Asthma and Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00662675
A Study of the Efficacy and Tolerability of Pancrelipase Microtablet (MT) Capsules for the Treatment of Cystic Fibrosis-dependent Exocrine Pancreatic Insufficiency No drug interventions treatment 3 completed NCT02416375
Home Monitoring to Predict Exacerbation in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01455675
Efficacy Study of IgY (Antibody Against Pseudomonas) in Cystic Fibrosis Patients No drug interventions prevention 3 completed NCT00008775
Pressure Support Ventilation During CF Exacerbations No drug interventions treatment Not Available suspended NCT02668575
Integrating Supportive Care in Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT03312075
Epidemiology and Clinical Characteristics of Non-Tuberculous Mycobacteria Infections in Cystic Fibrosis Patients. No drug interventions Not Available Not Available unknown_status NCT00572975
Malabsorption Blood Test:Toward a Novel Approach to Quantify Steatorrhea No drug interventions diagnostic 4 completed NCT00244270
Cystic Fibrosis and Totally Implantable Vascular Access Devices No drug interventions diagnostic 4 completed NCT00890370
Should Any One Airway Clearance Technique be Recommended for People With Cystic Fibrosis? No drug interventions treatment 4 completed NCT03502070
Human Factors Study to Validate the User Interface of TOBI Podhaler Using Placebo Capsules No drug interventions other 4 completed NCT00418470
Prolonging the Duration of Peripheral Venous Catheters in Cystic Fibrosis People No drug interventions prevention 4 terminated NCT01572870
Duplication in CHIT1 Gene and the Risk for Aspergillus Lung Disease in CF Patients No drug interventions Not Available Not Available completed NCT00255242
Effect of Simvastatin on CF Airway Inflammation No drug interventions treatment 1 completed NCT01799642
Evaluating Sensations of Breathlessness in Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03748199
Clinical Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of POL6014 in Patients With CF No drug interventions treatment 1 / 2 completed NCT03256799
Evaluation of Ivacaftor in Patients Using Ataluren for Nonsense Mutations No drug interventions treatment 4 completed NCT01486199
Imaging Airway Liquid Absorption in Cystic Fibrosis No drug interventions basic_science Not Available completed NCT06128499
Development a Core Set for Adults With Cystic Fibrosis Based on the ICF No drug interventions Not Available Not Available not_yet_recruiting NCT01051999
Glutamine Supplementation in Cystic Fibrosis No drug interventions prevention 2 completed NCT02598999
Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients No drug interventions treatment 1 terminated NCT02225899
BioEnergetics and Metabolomics in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02139306
Study of Ataluren in Nonsense Mutation Cystic Fibrosis (ACT CF) No drug interventions treatment 3 completed NCT00953706
Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Homozygous for the F508del-CFTR Mutation No drug interventions treatment 2 terminated NCT01031706
Effect of Hypertonic Saline on Mucus Clearance in Children Ages 5-12 With Cystic Fibrosis No drug interventions treatment Not Available completed NCT03820349
Cystic Fibrosis and Cognitive Function No drug interventions Not Available Not Available completed NCT01658449
Comparison of the Tolerability of Two Formulations of Hypertonic Saline in Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT00570349
Safety and Tolerability of Inhaled Nitric Oxide in Patients With Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT01375049
Aztreonam Lysine for Pseudomonas Infection Eradication Study No drug interventions treatment 2 completed NCT01460849
Assess Increased Mortality Risk With Each Year of Delayed Tobramycin Solution (TIS) Initiation, and Effect of TIS on Mortality Across Study Centers No drug interventions Not Available Not Available withdrawn NCT00185549
An Interactive Program to Improve Care for Children With CF No drug interventions educational_counseling_training Not Available completed NCT05844449
Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older treatment 3 enrolling_by_invitation NCT05076149
A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation treatment 3 completed NCT03653949
Effects of Aerobic Interval Training on Glucose Tolerance in Children and Adolescents With Cystic Fibrosis No drug interventions treatment Not Available unknown_status NCT00671736
Lancovutide (Moli1901) Inhalation Solution Study in Adolescents and Adults With Cystic Fibrosis No drug interventions treatment 2 completed NCT03902236
Reaction Time and Postural Control in Individuals With Cystic Fibrosis and Bronchiectasis No drug interventions Not Available Not Available unknown_status NCT01375036
Registry to Monitor the Susceptibility to Aztreonam of Pseudomonas Aeruginosa Isolates From Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT05704036
Estrogen Supplementation and Bone Health in Women With CF treatment 4 recruiting NCT01810536
High Flow Nasal Oxygen for Children With Cystic Fibrosis Presenting With Respiratory Failure - a Randomized Controlled Study No drug interventions treatment Not Available terminated NCT00406536
Study of LYM-X-SORB™ to Improve Fatty Acid and Choline Status in Children With CF and PI No drug interventions supportive_care 2 completed NCT02275936
Study of N91115 in Patients With Cystic Fibrosis Homozygous F508del-CFTR Mutation No drug interventions treatment 1 completed NCT04825236
MyVoice:CF Decision Aid for Women With Cystic Fibrosis No drug interventions health_services_research Not Available completed NCT05614336
COVID-19 Antibody Responses in Cystic Fibrosis No drug interventions other Not Available recruiting NCT01460836
Indirect Comparison of Tobramycin Solution for Inhalation Versus Aztreonam Lysine for Inhalation in the Treatment of Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00411736
Scandinavian Cystic Fibrosis Azithromycin Study No drug interventions treatment 4 completed NCT02589236
Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation No drug interventions treatment 2 completed NCT04206436
CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis No drug interventions Not Available Not Available active_not_recruiting NCT00786513
Use of a Biofilm Antimicrobial Susceptibility Assay to Guide Antibiotic Therapy No drug interventions treatment 2 completed NCT01025713
A Phase 1 Trial to Assess the Safety, Tolerability, and Pharmacokinetics of GS 9411 in Subjects With Cystic Fibrosis (CF) No drug interventions treatment 1 withdrawn NCT03589313
Pharmacokinetics of GLPG3067 in Male Subjects With Cystic Fibrosis. No drug interventions treatment 1 completed NCT03911713
A Phase 2 Study to Evaluate Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis No drug interventions treatment 2 completed NCT01805713
Biomarkers of Injury and Destruction in the Cystic Fibrosis Lung No drug interventions Not Available Not Available completed NCT03903913
Safety, Tolerability and Efficacy of S-1226 in Cystic Fibrosis and Non CF Bronchiectasis No drug interventions treatment 2 unknown_status NCT03357913
Non-respiratory Comorbidities Observed in Pulmonary French Transplant Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01783613
Eficacy of Long-term Suplementation With Docosahexaenoic Acid in Patients With Cystic Fibrosis No drug interventions treatment Not Available completed NCT02680418
Pharmacokinetics of FDL169 in Healthy Female Subjects No drug interventions Not Available 1 completed NCT02477319
A Two-Part Multicenter Prospective Longitudinal Study of CFTR-dependent Disease Profiling in Cystic Fibrosis (PROSPECT) No drug interventions Not Available Not Available completed NCT01832519
Using MRI to Observe Lung Changes in Infants With CF Compared to Infants Without CF No drug interventions Not Available Not Available completed NCT01044719
Duration of Antibiotics in Infective Exacerbations of Cystic Fibrosis No drug interventions treatment 4 unknown_status NCT03150719
A Study to Evaluate Safety, Efficacy, and Tolerability of TEZ/IVA in Orkambi® (Lumacaftor/Ivacaftor) -Experienced Subjects With Cystic Fibrosis (CF) No drug interventions treatment 3 completed NCT02390219
Study to Evaluate Lumacaftor and Ivacaftor Combination Therapy in Subjects 12 Years and Older With Advanced Lung Disease No drug interventions treatment 3 completed NCT04553419
Antibiotic Treatment Of Staphylococcus Aureus In Stable People With CF No drug interventions treatment 3 recruiting NCT04277819
The Use of Novel Diagnostic Tools to Increase Detection of Early Fibrosis in Cystic Fibrosis Related Liver Disease to Improve Clinical Management No drug interventions Not Available Not Available completed NCT03020719
The Role of Oral Glutathione on Growth Parameters in Children With Cystic Fibrosis No drug interventions supportive_care 2 completed NCT03870841
The Effect of PC945 on Aspergillus Fumigatus Lung Infection in Patients With Cystic Fibrosis No drug interventions treatment 2 terminated NCT05001841
Renal Failure Following Lung Transplantation in Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT00004441
Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis treatment Not Available completed NCT00635141
The Effect of Hypertonic Saline on the Lung Clearance Index in Patients With Cystic Fibrosis No drug interventions treatment 3 completed NCT05668741
A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF) treatment 1 / 2 recruiting NCT00566241
IGF-1 Therapy in Patients With Cystic Fibrosis No drug interventions treatment 1 terminated NCT00408317
Safety and Efficacy Study of ULTRASE® MT20 in Participants With Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (PI) No drug interventions treatment 3 completed NCT02043717
Increased Vitamin D Reduces Pulmonary Exacerbations in CF No drug interventions Not Available Not Available completed NCT06112717
The Application of the Self Care Deficit Nursing Theory in Adolescents With Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT01345617
A Study of Sweat Testing Using a Quantitative Patch No drug interventions Not Available Not Available completed NCT03497117
19F MRI of Ventilation in Subjects With Cystic Fibrosis Undergoing Treatment for Pulmonary Exacerbation No drug interventions other 0 terminated NCT01404234
Safety of AZLI in Children With Cystic Fibrosis (CF) and Chronic Pseudomonas Aeruginosa in the Lower Airways No drug interventions treatment 3 completed NCT00205634
Macrolide Antibiotic Therapy for Patients With Cystic Fibrosis treatment 2 completed NCT02444234
Pharmacokinetics of Tedizolid Phosphate in Cystic Fibrosis No drug interventions other 4 completed NCT04992234
COVID-19 Antibody Responses in Cystic Fibrosis No drug interventions Not Available Not Available active_not_recruiting NCT01712334
A Study of the Comparable Efficacy and Safety of Pulmozyme (Dornase Alfa) Delivered by the eRapid Nebulizer System in Patients With Cystic Fibrosis No drug interventions treatment 4 completed NCT00628134
Self-dispersing Liquids as Aerosol Drug Carriers No drug interventions basic_science Not Available completed NCT02172534
Safety, Tolerability and Pharmacokinetics of Tiotropium in Cystic Fibrosis Patients No drug interventions treatment 1 completed NCT03258424
Study Assessing PTI-428 Safety, Tolerability, and Pharmacokinetics in Subjects With Cystic Fibrosis on KALYDECO® as Background Therapy No drug interventions treatment 1 completed NCT03938324
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions No drug interventions supportive_care Not Available completed NCT05295524
Description of the Short-term Effects of KAFTRIO® by Continuous Monitoring With the PHEAL-CR-K Application in Real Life in Patients With Cystic Fibrosis Eligible for KAFTRIO® Treatment No drug interventions other Not Available unknown_status NCT01057524
High Frequency Chest Wall Oscillation and Cystic Fibrosis No drug interventions treatment 3 completed NCT02591524
Upper and Lower Airway Colonization in Cystic Fibrosis Patients After Lung Transplantation No drug interventions diagnostic Not Available unknown_status NCT00996424
The Effect of Inhaled N-Acetylcysteine Compared to Normal Saline on Sputum Rheology and Lung Function No drug interventions treatment 4 terminated NCT05932316
Evaluating Bronchodilator Response in Patients With Bronchiectasis diagnostic Not Available recruiting NCT02547116
Epidemiology and Treatment of Small-colony Variant Staphylococcus Aureus in Cystic Fibrosis No drug interventions treatment 4 withdrawn NCT03674216
Study of Peripherally Inserted Venous Catheters in Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT00043316
Interferon Gamma-1b by Inhalation for the Treatment of Patients With Cystic Fibrosis treatment 1 / 2 completed NCT04527796
Influence of a Residential Rehabilitation Program on Body Composition in Patients With Cystic Fibrosis No drug interventions Not Available Not Available terminated NCT06299696
A Study of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) in Healthy Adult Panelists basic_science 1 completed NCT00777296
Multidose Safety and Tolerability Study of Dose Escalation of Liposomal Amikacin for Inhalation (ARIKACE™) No drug interventions treatment 1 / 2 completed NCT01424696
Baby Observational and Nutritional Study No drug interventions Not Available Not Available completed NCT04215796
Evaluation of the ReX-C System, in Patients Receiving CFTR Modulators for the Treatment of Cystic Fibrosis (CF). No drug interventions treatment Not Available unknown_status NCT01013896
Building Adherence to Live With And Navigate my Cystic Fibrosis (CF) Experience No drug interventions Not Available Not Available completed NCT03911258
Epidemiology of the Nasal Flora at the Reference Center for Cystic Fibrosis of Queen Fabiola Children's University Hospital. No drug interventions diagnostic Not Available unknown_status NCT03948958
PREMO Study: to Investigate Port REMoval Outcomes No drug interventions prevention Not Available completed NCT04476758
Immune Profiles in CF Fungal Infection No drug interventions Not Available Not Available completed NCT03309358
A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis No drug interventions treatment 1 terminated NCT04453358
Cystic Fibrosis Remote Monitoring System No drug interventions supportive_care Not Available unknown_status NCT01772758
Cystic Fibrosis and Endothelial Function: At Rest and During Exercise No drug interventions other 2 completed NCT02057458
Blood Flow and Vascular Function in Cystic Fibrosis No drug interventions treatment 2 completed NCT02498535
Efficacy and Safety of Inhaled Nitric Oxide (NO) in Cystic Fibrosis (CF) Patients No drug interventions treatment 2 terminated NCT02211235
Glycemic Monitoring in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01509235
Self Drainage in Pediatric Cystic Fibrosis Patients No drug interventions supportive_care Not Available completed NCT01840735
Phase 1b Safety, Tolerability, and PK Study to Assess GS-5737 in Subjects With CF No drug interventions treatment 1 completed NCT01944735
Phase 1 Study Assessing the Safety and Tolerability of CTX-4430 in Cystic Fibrosis Patients No drug interventions treatment 1 completed NCT00006063
Randomized Study of Pancrelipase With Bicarbonate (PANCRECARB) Capsules in Reducing Steatorrhea in Patients With Cystic Fibrosis treatment Not Available completed NCT03500263
Safety, Tolerability, and Pharmacokinetics of PTI-808, PTI-801, and PTI-428 Combination Therapy in Subjects With Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT02083263
Non Invasive Ventilation as Airway Clearance in Patients With Cystic Fibrosis No drug interventions treatment Not Available completed NCT00234663
PTC124 for Cystic Fibrosis treatment 2 completed NCT01768663
A Phase 1 Study to Examine the Drug-Drug Interaction of Ciprofloxacin, Itraconazole, and Rifampin on the Combination of Lumacaftor With Ivacaftor in Healthy Adult Subjects No drug interventions treatment 1 completed NCT00073463
Safety and Efficacy of Recombinant Adeno-Associated Virus Containing the CFTR Gene in the Treatment of Cystic Fibrosis No drug interventions treatment 2 / 3 terminated NCT04702386
Concerns of Children Whose Parents Have Cystic Fibrosis No drug interventions Not Available Not Available completed NCT04460586
Pharmacokinetics of Omadacycline in Cystic Fibrosis No drug interventions other 4 completed NCT03434886
Outcomes in CF Patients Accessing Their Registry Health Records No drug interventions supportive_care Not Available completed NCT00231686
Effects of a 6-Months Physical Conditioning Program in Patients With Cystic Fibrosis No drug interventions treatment 2 / 3 completed NCT01183286
CFfone: A Cell Phone Support Program for Adolescents With Cystic Fibrosis No drug interventions Not Available 2 unknown_status NCT03783286
Ivacaftor Treatment in 4 Month to 2 Year Old CF Subjects No drug interventions Not Available Not Available completed NCT00794586
Study Evaluating Fosfomycin/Tobramycin for Inhalation in Cystic Fibrosis Patients With Pseudomonas Aeruginosa Lung Infection No drug interventions treatment 2 completed NCT04489186
Continuous Cardiorespiratory Monitoring in Cystic Fibrosis No drug interventions device_feasibility Not Available completed NCT03534986
Effect of High Frequency Chest Wall Oscillation Vests on Spirometry Measurements No drug interventions treatment Not Available completed NCT05099939
Identification of Dysglycemia With Continuous Glucose Monitoring to Assess Clinical Evolution in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT01401439
Assessment of Fat Free Mass Index and Its Impact on Health in Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02600039
The Short-term Effect of ELTGOL on Pulmonary Ventilation Valued Through Electrical Impedance Tomography in Cystic Fibrosis Patients No drug interventions treatment Not Available unknown_status NCT02934139
MAD Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Cavosonstat (N91115) in Healthy Subjects (SNO-9) No drug interventions basic_science 1 completed NCT01509339
Pharmacokinetics of Vancomycin for Inhalation in Cystic Fibrosis No drug interventions treatment 1 withdrawn NCT04579939
Oral Glucose Tolerance Testing Using Candy for Cystic Fibrosis No drug interventions basic_science Not Available completed NCT04306939
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study No drug interventions Not Available Not Available suspended NCT01641822
Phase 3 Study of Aztreonam for Inhalation Solution (AZLI) in a Continuous Alternating Therapy Regimen for the Treatment of Chronic Pseudomonas Aeruginosa Infection in Patients With CF No drug interventions treatment 3 completed NCT02884622
DNA Methylation and Lung Disease in Cystic Fibrosis No drug interventions basic_science Not Available completed NCT02750722
Exercise and Oscillatory Positive Expiratory Pressure Therapy in Cystic Fibrosis No drug interventions treatment Not Available completed NCT06251622
Muscle Function and Physical Activity in the Modern Era of Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT02109822
Pilot Observational Study to Determine Feasibility of a Standardized Treatment of Pulmonary Exacerb. in Patients With CF No drug interventions Not Available Not Available completed NCT02157922
A Phase IIb Study of OligoG in Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT03734822
Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia No drug interventions other Not Available completed NCT03632525
Intravenous Iron in Adults With Cystic Fibrosis No drug interventions treatment 4 completed NCT01806025
Correlation Between Haptoglobin Phenotypes and Infectious and Other Complications in Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT02170025
Early Signs of Efficacy Study With Riociguat in Adult Homozygous Delta F508 Cystic Fibrosis Patients No drug interventions treatment 2 terminated NCT03069625
Sit-to-stand Test in Cystic Fibrosis Children and Adolescents No drug interventions screening Not Available completed NCT02888730
Tobramycin Delivered by Nebulized Sonic Aerosol for Chronic Rhinosinusitis Treatment of Cystic Fibrosis Patients No drug interventions treatment 3 terminated NCT03737630
Inspiratory Muscle Training in Individuals With Cystic Fibrosis No drug interventions treatment Not Available completed NCT00908830
Effects of Mycophenolate Mofetil in Cystic Fibrosis Lung Transplant Patients No drug interventions Not Available Not Available completed NCT05699148
Gut Imaging for Function and Transit in Cystic Fibrosis 3 Junior Not Available Not Available active_not_recruiting NCT03525548
A Study of VX-445 Combination Therapy in CF Subjects Homozygous for F508del (F/F) No drug interventions treatment 3 completed NCT00757848
A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Cystic Fibrosis No drug interventions basic_science 2 completed NCT03698448
A Dose-finding Study of Inhaled OligoG vs Placebo in Patients With Cystic Fibrosis No drug interventions treatment 2 / 3 withdrawn NCT01852448
Genetics of Insulin and Incretins in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT03894657
Validation of Respiratory Epithelial Functional Assessment to Predict Clinical Efficacy of Orkambi®. No drug interventions other Not Available completed NCT02127957
Effects of an Exercise Program Among CF Patients With Dysglycemia No drug interventions prevention Not Available completed NCT01614457
Study of Ivacaftor in Subjects With Cystic Fibrosis (CF) Who Have the R117H-CF Transmembrane Conductance Regulator (CFTR) Mutation (KONDUCT) No drug interventions treatment 3 completed NCT02131857
The Effectiveness of a Systemic Mindfulness-based Intervention Program in a Cystic Fibrosis Clinic No drug interventions supportive_care Not Available unknown_status NCT02359357
FTIH - Single and Repeat Oral Doses of FDL169 in Healthy Volunteers No drug interventions Not Available 1 completed NCT02690857
Study of Docosahexanoic Acid in Patients With Cystic Fibrosis (CF) No drug interventions treatment 2 completed NCT03381157
Fidgety Movements in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03056326
A Study to Investigate Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of CHF6333 in Healthy Subjects No drug interventions treatment 1 completed NCT02906826
Adherence to Airway Clearance. Novel Approaches to Improving Adherence No drug interventions Not Available Not Available unknown_status NCT02277626
Electro Flo 5000 and Vest Therapy No drug interventions treatment 4 completed NCT00712166
Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Patients With Cystic Fibrosis, Mild Lung Disease, and P. Aeruginosa No drug interventions treatment 3 completed NCT01537666
Inhaled Vancomycin Tolerability, Safety and Pharmacokinetics No drug interventions treatment 1 completed NCT06280066
An Intervention-Based Approach to Strengthen the Psychological Health of Children With Cystic Fibrosis and Their Mothers No drug interventions supportive_care Not Available recruiting NCT01325766
Study of Yoga as a Therapy for Cystic Fibrosis (CF) Patients No drug interventions Not Available Not Available unknown_status NCT05635266
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives No drug interventions Not Available Not Available recruiting NCT03139266
Project UPLIFT to Reduce Anxiety and Depression in CF Patients No drug interventions supportive_care Not Available completed NCT06299566
Perceptions of the CF Screening Protocol Incorporating NGS No drug interventions Not Available Not Available completed NCT01060566
Study of VX-770 on Midazolam and Rosiglitazone and the Effect of Fluconazole on VX-770 No drug interventions treatment 1 completed NCT02875366
A Study of the Effects of Lumacaftor/Ivacaftor (LUM/IVA) on Exercise Tolerance in Subjects With Cystic Fibrosis (CF), Homozygous for the F508del-CFTR Mutation No drug interventions other 4 completed NCT02603666
Elastography of the Liver in Cystic Fibrosis Patients. Diagnostic and Prognostic Aspects No drug interventions diagnostic Not Available completed NCT00037765
Gene Modifiers of Cystic Fibrosis Lung Disease No drug interventions Not Available Not Available active_not_recruiting NCT06120465
YOGA-CF (Yoga Outcomes Get Assessed in Cystic Fibrosis) No drug interventions treatment Not Available recruiting NCT01059565
Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Patients With Cystic Fibrosis and Chronic Burkholderia Species Infection No drug interventions treatment 3 completed NCT03279965
MRI in Cystic Fibrosis and Primary Ciliary Dyskinesia No drug interventions Not Available Not Available unknown_status NCT00638365
Dose Escalation Study of KB001 in Cystic Fibrosis Patients Infected With Pseudomonas Aeruginosa No drug interventions treatment 1 / 2 completed NCT04599465
A Study to Assess the Effect of ELX/TEZ/IVA on Glucose Tolerance in Participants With Cystic Fibrosis (CF) No drug interventions treatment 3 completed NCT00405665
The Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis No drug interventions treatment 2 completed NCT01315665
Effect of Sulforaphane in Broccoli Sprouts on Nrf2 Activation No drug interventions basic_science Not Available completed NCT00885365
A Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI® No drug interventions treatment 3 completed NCT04999865
Cystic Fibrosis Reproductive and Sexual Health Collaborative: Building Online Research Partnerships No drug interventions Not Available Not Available unknown_status NCT05788965
Semaglutide in CFRD treatment 2 / 3 recruiting NCT01983774
Effect of Proton Pump Inhibitors on CF Pulmonary Exacerbations No drug interventions treatment 2 completed NCT03525574
A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy No drug interventions treatment 3 completed NCT01270074
Prevention of Bronchiectasis in Infants With Cystic Fibrosis No drug interventions prevention 3 completed NCT03450720
Pharmacokinetics of GLPG2737 in Male Subjects With Cystic Fibrosis No drug interventions treatment 1 completed NCT01543620
Prospective Observational Study to Evaluate Biomarkers of Aminoglycoside Nephrotoxicity in Patients With Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT03760120
Short-term Effects of Physiotherapy on LCI No drug interventions treatment Not Available completed NCT05519020
Inhaled Therapy Adherence and Outcomes to Kaftrio in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT00690820
Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency (PEI) Due to Cystic Fibrosis (CF) No drug interventions treatment 3 completed NCT03910920
Cross Transmissions of Pseudomonas Aeruginosa Between Children From a Same Cystic Fibrosis Center. No drug interventions Not Available Not Available unknown_status NCT04002882
Role of Body Fat Distribution in Metabolic and Pulmonary Decline in Cystic Fibrosis (ORBIT-CF) No drug interventions Not Available Not Available recruiting NCT02700282
Backpack Carrying in Children With Cystic Fibrosis No drug interventions prevention 4 completed NCT04828382
Prospective Study of Pregnancy in Women With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT03699982
Resting Energy Expenditure in Patients With Cystic Fibrosis: A Pilot Study No drug interventions treatment Not Available unknown_status NCT00130182
A Study in Pediatric Patients With Cystic Fibrosis Lung Disease treatment 2 completed NCT05054582
COVID-19 Antibody Responses In Cystic Fibrosis: CAR-CF No drug interventions Not Available Not Available active_not_recruiting NCT00219882
Safety Study of Orally Administered Curcuminoids in Adult Subjects With Cystic Fibrosis treatment 1 completed NCT01721382
Treatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic Fibrosis No drug interventions diagnostic 1 completed NCT01132482
Effects of Sildenafil on CFTR-dependent Ion Transport Activity No drug interventions treatment 2 completed NCT00513682
Efficacy and Safety of Ultrase® MT20 in Improving the Coefficient of Fat Absorption (CFA) in Children With Cystic Fibrosis (CF) and Pancreatic Insufficiency (PI) No drug interventions treatment 3 completed NCT06163482
Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT02693431
Impact of Art Therapy on Anxiety Identified During Hospitalizations Among Children With Cystic Fibrosis Aged 8 to 13 No drug interventions Not Available Not Available completed NCT03190031
Respiratory Muscle Training in CF Patients No drug interventions treatment Not Available completed NCT04673331
Physical Activity, Exercise Capacity and Coronavirus Phobia of Adult Cystic Fibrosis Patients During COVID-19 Pandemic No drug interventions Not Available Not Available completed NCT03522831
CF Bronchodilation No drug interventions supportive_care Not Available active_not_recruiting NCT02212431
First Study of Oral Cysteamine in Cystic Fibrosis No drug interventions Not Available 1 / 2 completed NCT01883531
Crossover Trial Determining the Efficacy of Dry Powder Mannitol to Improve Lung Function in Subjects Aged 6-17 Years No drug interventions treatment 2 completed NCT03052231
Interactive Mobile Health Information to Enhance Patient Care at a Cystic Fibrosis Center No drug interventions health_services_research Not Available completed NCT03516331
A Drug-Drug Interaction Study of FDL169 and FDL176 in Healthy Subjects No drug interventions treatment 1 completed NCT03256773
High Resolution Micro OCT Imaging No drug interventions Not Available Not Available recruiting NCT01531673
Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation No drug interventions treatment 2 completed NCT04561973
Pain in Patients With Cystic Fibrosis in Rouen University Hospital No drug interventions Not Available Not Available completed NCT06506773
Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF) No drug interventions Not Available Not Available recruiting NCT00450073
Improving Vitamin D Status In Cystic Fibrosis No drug interventions treatment Not Available completed NCT02514473
A Study to Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects With CF, Homozygous for the F508del-CFTR Mutation No drug interventions treatment 3 completed NCT00097773
Comparison of Two Treatment Regimens to Reduce PA Infection in Children With Cystic Fibrosis prevention 2 completed NCT05526027
Real-world Efficacy and Safety of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulator Therapy in Adult Patients With Cystic Fibrosis (CF) No drug interventions treatment Not Available not_yet_recruiting NCT03140527
Study Assessing the Safety, Tolerability, Pharmacokinetics, Food Effect, and Drug-Drug Interactions of PTI-801 in Healthy Volunteers, and Safety, Tolerability, and Pharmacokinetics of PTI-801 in Subjects With Cystic Fibrosis No drug interventions treatment 1 completed NCT00909727
Study of Ivacaftor in Cystic Fibrosis Subjects Aged 6 to 11 Years With the G551D Mutation No drug interventions treatment 3 completed NCT02724527
Study of Cavosonstat (N91115) in CF Patients Who Are Heterozygous for F508del-CFTR and a Gating Mutation and Being Treated With Ivacaftor No drug interventions treatment 2 unknown_status NCT01594827
Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP) No drug interventions treatment 2 completed NCT03078127
Researching the Effects of Airway Clearance Therapies in Cystic Fibrosis No drug interventions basic_science Not Available completed NCT04114227
Acceptance and Commitment Therapy vs. Supportive Psychotherapy With Cystic Fibrosis Patients No drug interventions supportive_care Not Available completed NCT02653027
Effect of Lumacaftor-ivacaftor on Glucose Handling and Tolerance in Cystic Fibrosis Phe508del No drug interventions screening Not Available withdrawn NCT02504827
Steady-state Pharmacokinetics of Ceftazidime/Avibactam in Cystic Fibrosis No drug interventions other 4 completed NCT02202876
Redox Imbalance and the Development of Cystic Fibrosis Diabetes No drug interventions treatment Not Available completed NCT01192360
Dynamic Contrast Enhanced Magnetic Resonance Perfusion Imaging in Congenital Heart Disease and Lung Disease No drug interventions treatment 3 completed NCT00669760
Dissection of Staphylococcus Aureus Infection From Colonization in Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT05276960
Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CF supportive_care 4 unknown_status NCT03227094
Simplification of CF-related Diabetes Screening at Home No drug interventions screening Not Available completed NCT06399094
Frequency-time Analysis of Pathological Lung Sounds: Detection and Quantification of Pathological Sounds in Patients With Cystic Fibrosis, Pulmonary Fibrosis or COPD (Chronic Obstructive Pulmonary Disease) No drug interventions Not Available Not Available not_yet_recruiting NCT05829694
Health Outcomes of Parents With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT06296394
Health Outcomes of Parents With Cystic Fibrosis-Aim 2 No drug interventions Not Available Not Available recruiting NCT01851694
Beta-cell Response to Incretin Hormones in Cystic Fibrosis No drug interventions other Not Available recruiting NCT04016194
Prediction of Survival in Children With Cystic Fibrosis Using the Multiple-breath Washout No drug interventions Not Available Not Available completed NCT00792194
Improvement of Aerobic Capacity in Cystic Fibrosis Patients With a One-year Home Training Period No drug interventions Not Available Not Available completed NCT05173194
Remotely Supervised Exercise for Adults With Cystic Fibrosis No drug interventions treatment Not Available completed NCT03591094
Study Assessing PTI-428 Safety, Tolerability, Pharmacokinetics and Effect in Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT00104494
Zinc Homeostasis and Kinetics in Children With Cystic Fibrosis (CF) treatment Not Available completed NCT01315691
Study to Evaluate Arikace™ in CF Patients With Chronic Infection Due to Pseudomonas Aeruginosa No drug interventions treatment 3 withdrawn NCT00274391
Efficacy of Amiloride and Hypertonic Saline in Cystic Fibrosis Not Available 2 completed NCT02141191
A Study of Lung Clearance After Hypertonic Saline Delivery Using the tPAD Device No drug interventions treatment 1 completed NCT02810691
The Effect of Soluble Fiber to Reduce Post-prandial Glycemic Excursion in Adults With Cystic Fibrosis No drug interventions prevention Not Available completed NCT03447262
A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy No drug interventions treatment 3 terminated NCT04556162
Evaluation of Salt Status in Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03091062
Evaluation of an Airway Clearance System No drug interventions treatment Not Available completed NCT00546962
Tissue Bank for Pulmonary Diseases No drug interventions Not Available Not Available unknown_status NCT01616862
The Carrier Rates of Pseudomonas Aeruginosa in Family Members of Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00008762
Bone Health of People With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02759562
Effect of Andecaliximab on FEV1 in Adults With Cystic Fibrosis No drug interventions treatment 2 terminated NCT02325362
Effect of Miglustat on the Nasal Potential Difference in Patients With Cystic Fibrosis Homozygous for the F508del Mutation No drug interventions treatment 2 / 3 completed NCT06370962
Circadian Rhythm Disorders in Children With Cystic Fibrosis Under CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Modulators No drug interventions Not Available Not Available recruiting NCT02992080
Small Circulating RNA as Molecular Markers of Lung Disease in Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT04923880
Pragmatic Implementation Trial of a CF Primary Palliative Care Intervention No drug interventions health_services_research Not Available active_not_recruiting NCT04568980
Assessment of Contraceptive Safety and Effectiveness in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02679729
To Assess the Safety, Tolerability and Pharmacokinetics of AZD5634 Following Inhaled and Intravenous (IV)Dose Administration No drug interventions basic_science 1 completed NCT00515229
Anti-Inflammatory Pulmonal Therapy of CF-Patients With Amitriptyline and Placebo No drug interventions treatment 2 completed NCT03921229
Tele-Coaching Intervention to Improve Treatment Adherence in Cystic Fibrosis No drug interventions other Not Available completed NCT01548729
Metabolic Efficiency of Combined Pancreatic Islet and Lung Transplant for the Treatment of End-Stage Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT04060329
Measuring and Improving Coproduction Using coopeRATE No drug interventions health_services_research Not Available terminated NCT00004829
Phase III Randomized Study of the Inhalation of Tobramycin in Patients With Cystic Fibrosis treatment 3 completed NCT01837589
Quantitative Computed Tomodensitometry in Patients With Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT00557089
The Effect of rhDNase on Ventilation Inhomogeneity in Patients With Cystic Fibrosis No drug interventions treatment 4 completed NCT01116089
Pharmacokinetic Study of Bramitob® Administered for Inhalation by PARI eFlow® vs PARI LC® PLUS Nebulizer No drug interventions treatment 1 completed NCT03016689
The Sinonasal Cavity as a Reservoir for Upper Airway Bacterial Development No drug interventions Not Available Not Available recruiting NCT06106789
A Study of the Clinical Benefit of Tobramycin Inhalation Solution No drug interventions Not Available Not Available active_not_recruiting NCT02269189
Safety, Tolerability and Pharmacokinetics of BIIL 284 BS in Adult and Pediatric Cystic Fibrosis (CF) Patients No drug interventions treatment 1 completed NCT04930289
Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs No drug interventions Not Available Not Available enrolling_by_invitation NCT03956589
Functional Respiratory Imaging and Orkambi in CF No drug interventions treatment 4 terminated NCT01349192
Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF) No drug interventions treatment 2 terminated NCT01848392
Extrapulmonary Effects of Cystic Fibrosis on Physical Activity of Adult Patients. No drug interventions Not Available Not Available completed NCT06311292
Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis No drug interventions other Not Available recruiting NCT02048592
Impact of Immunonutrition on the Patients With Cystic Fibrosis No drug interventions supportive_care 4 unknown_status NCT01973192
Viral Pathogenesis of Early Cystic Fibrosis Lung Disease No drug interventions Not Available Not Available completed NCT02850692
Portal Hypertension and Systemic Endothelial Function No drug interventions prevention Not Available unknown_status NCT05420844
Pilot Study to Evaluate a Voice Journaling Application in Adolescents With Cystic Fibrosis No drug interventions other Not Available active_not_recruiting NCT02070744
Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion No drug interventions treatment 2 completed NCT02803944
Continuous Azithromycin in Cystic Fibrosis Patients Beyond Two Years No drug interventions Not Available Not Available completed NCT00839644
Airway Secretion Clearance in Cystic Fibrosis No drug interventions treatment Not Available terminated NCT01958944
Evaluation of the Safety and Tolerability of Inhaled Nitric Oxide to Subjects With Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT03525444
A Phase 3 Study of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF) No drug interventions treatment 3 completed NCT00530244
Use of Formula Fortified With DHA in Infants With Cystic Fibrosis No drug interventions prevention Not Available completed NCT06274840
COVID-19 Antibody Responses In Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT04058340
Taste Receptors Regulation in CF Patients No drug interventions treatment Not Available unknown_status NCT01078740
Detection of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity in Rectal Tissues From Human Subjects No drug interventions Not Available Not Available completed NCT06191640
Sinus Disease in Young Children With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT00004440
Study of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis treatment Not Available completed NCT01788267
Bone Microarchitecture in Young Cystic Fibrosis Patients No drug interventions diagnostic Not Available completed NCT03237767
A CFit Study - Acute Exercise No drug interventions treatment Not Available terminated NCT02308267
Impaired Secretory IgA and Mucosal Immunity in Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT01621867
Repeated Application of Gene Therapy in CF Patients No drug interventions treatment 2 completed NCT02464267
Developing and Validating a Patient-reported Outcome Instrument to Monitor Symptom Management in Pulmonary Exacerbation in CF No drug interventions Not Available Not Available completed NCT05944367
The Use of Breath Volatile Organic Compounds in Early Detection of Acute Pulmonary Exacerbations in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00323167
Rare Genetic Disorders of the Breathing Airways No drug interventions Not Available Not Available completed NCT02378467
Saline Hypertonic in Preschoolers No drug interventions treatment Not Available completed NCT00789867
Single Dose of pGM169/GL67A in CF Patients No drug interventions treatment 1 / 2 completed NCT04825067
Remote Monitoring of High-Risk Patients With Chronic Cardiopulmonary Diseases No drug interventions diagnostic Not Available unknown_status NCT01685801
Pilot Study Testing the Effect of Ivacaftor on Lung Function in Subjects With Cystic Fibrosis and Residual CFTR Function No drug interventions treatment 2 completed NCT02750501
Absorption and Safety With Sustained Use of RELiZORB Evaluation (ASSURE) Study No drug interventions treatment Not Available completed NCT04926701
A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD001 in Healthy Subjects No drug interventions treatment 1 completed NCT02677701
Testing the Effect of Adding Chronic Oral Azithromycin to Inhaled Tobramycin in People With Cystic Fibrosis (CF) No drug interventions treatment 4 completed NCT04994301
Evaluation of Lung T1-MRI in Pediatric Cystic Fibrosis Patients No drug interventions Not Available Not Available recruiting NCT01172301
Leucine-enriched Essential Amino Acid Intake to Optimize Protein Anabolism in Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01323101
Doxycycline Effects on Inflammation in Cystic Fibrosis No drug interventions treatment 4 completed NCT00765401
An Investigation of the Association Between Helicobacter Pylori Infection and Abdominal Pain in Cystic Fibrosis Patients No drug interventions Not Available Not Available withdrawn NCT02234401
Non Invasive Ventilation for Acute Exacerbations in Adult CF No drug interventions supportive_care Not Available unknown_status NCT03919604
ECMO for Lung Transplantation in Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT00217204
An Effectiveness, Safety, and Palatability Study of Pancrelipase Microtablets in Infants and Toddlers With Cystic Fibrosis and Fat Malabsorption treatment 2 completed NCT00449904
Open-Label Phase III Long-Term Safety Trial of Liprotamase No drug interventions treatment 3 completed NCT03637504
Feasibility of a Mobile Medication Plan Application in CF Patient Care No drug interventions other Not Available completed NCT00564304
NPD Measurement in Infants No drug interventions Not Available Not Available unknown_status NCT02526004
Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified No drug interventions treatment Not Available completed NCT01348204
Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators No drug interventions basic_science 2 completed NCT04256772
Anti-IL5 and Other Biotherapies in Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT01329172
Nasal Mucin Oral Supplementation Treatment Respiratory Inflammation Using PUFA in Cystic Fibrosis (CF) Patients No drug interventions treatment Not Available terminated NCT01092572
Statins To Treat Adult Cystic Fibrosis No drug interventions treatment 1 / 2 withdrawn NCT06289972
Development,Validity and Reliability of a Caregiver Version of the Breathlessness Beliefs Questionnaire No drug interventions Not Available Not Available recruiting NCT04105972
A Study Evaluating the Efficacy and Safety of VX-445/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects, Homozygous for F508del No drug interventions treatment 3 completed NCT02518672
Pro-resolving Effect of MAG-DHA in Cystic Fibrosis (PREMDIC) No drug interventions treatment 2 terminated NCT02740868
Xenon-129 Lung Magnetic Resonance Imaging: Study of Healthy Volunteers and Participants With Pulmonary Disease No drug interventions diagnostic 2 recruiting NCT05561868
COVID-19 Antibody Responses in Cystic Fibrosis No drug interventions Not Available Not Available active_not_recruiting NCT06413368
Maralixibat in Patients With Cystic Fibrosis and Constipation, A Within-Subjects Pilot Study No drug interventions treatment 2 / 3 not_yet_recruiting NCT01694069
Continuous Infusion Piperacillin-tazobactam for the Treatment of Cystic Fibrosis No drug interventions treatment 4 terminated NCT00676169
The EPIC Observational Study No drug interventions Not Available Not Available completed NCT05590169
Effects of Telerehabilitation-based Exercises in Cystic Fibrosis No drug interventions treatment Not Available recruiting NCT01753869
Timing of Hypertonic Saline Inhalation Relative to Airways Clearance in Cystic Fibrosis No drug interventions treatment Not Available terminated NCT00241969
Behavioral & Nutritional Treatment to Help CF Preschoolers Grow No drug interventions treatment Not Available completed NCT01885169
LAIV (Flumist®) Administration in CF Patients No drug interventions Not Available Not Available unknown_status NCT06539169
FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases No drug interventions Not Available Not Available recruiting NCT05274269
Evaluation of Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis Subjects Without an F508del Mutation No drug interventions treatment 3 completed NCT04279769
Study to Evaluate the Safety of CB-280 in Patients With Cystic Fibrosis No drug interventions treatment 1 completed NCT00483769
One Year Glargine Treatment in CFRD Children and Adolescents No drug interventions treatment 4 completed NCT02501369
Investigating the Use of a Positive Parenting Programme to Improve Treatment Adherence in Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT01216046
Drug-Drug Interaction Study of VX-770 and VX-809 in Healthy Subjects No drug interventions treatment 1 completed NCT05157646
The Relationship Between CFTR Gene Mutations and Exercise Capacity No drug interventions basic_science Not Available withdrawn NCT00684346
18FDG-PET Imaging to Detect Changes in Airways Inflammation in Cystic Fibrosis Patients No drug interventions diagnostic 3 completed NCT06322446
Exercise in People With Cystic Fibrosis on CFTR Modulator Therapy No drug interventions treatment Not Available recruiting NCT06356246
Oral Health Status of Cystic Fibrosis Patients. An Online Survey in Collaboration With the Vaincre la Mucoviscidose Patient Association. No drug interventions Not Available Not Available not_yet_recruiting NCT00368446
Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease No drug interventions Not Available Not Available completed NCT00221546
Influence of DHA-rich Supplement on DHA-status and Health Evolution of Patients With Cystic Fibrosis No drug interventions treatment 2 completed NCT01070446
Choline Nutrition in Children With Cystic Fibrosis No drug interventions treatment Not Available completed NCT01946412
Roll-Over Study of Ivacaftor in Cystic Fibrosis Pediatric Subjects With a CF Transmembrane Conductance Regulator Gene (CFTR) Gating Mutation No drug interventions treatment 3 completed NCT02797912
LBM & Lung Function in Adolescents With CF No drug interventions Not Available Not Available completed NCT01117012
Rollover Study of VX-770 in Cystic Fibrosis Subjects No drug interventions treatment 3 completed NCT03109912
Do More, B'More, Live Fit No drug interventions treatment Not Available completed NCT05696912
Functional Tests to Resolve Unsolved Rare Diseases. Rares. No drug interventions diagnostic Not Available recruiting NCT00005112
Growth Hormone Use in Cystic Fibrosis - a Multicenter Study treatment 3 completed NCT04732910
Cystic Fibrosis Transmembrane Regulator (CFTR) Biomarker Study to Evaluate the Rescue of Mutant CFTR in Patients With Cystic Fibrosis Treated With CFTR-modulators No drug interventions Not Available Not Available recruiting NCT00271310
The Effects of Long Term Inhalation of Hypertonic Saline in Subjects With Cystic Fibrosis No drug interventions treatment 3 completed NCT02734810
SIMPLICITY: Studying Impacts on Malabsorption With Liprotamase in Cystic Fibrosis No drug interventions treatment 3 completed NCT00005110
A Multi-Centered Study of the Long-Term Effect of Salmeterol and Albuterol in Cystic Fibrosis treatment Not Available suspended NCT04118010
Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis No drug interventions treatment 4 completed NCT04531410
NETwork of Linoleic Acid Supplementation in Cystic Fibrosis No drug interventions treatment Not Available unknown_status NCT05408910
Rifaximin for Treatment of Bloating in Children and Adults With Cystic Fibrosis No drug interventions treatment 2 / 3 not_yet_recruiting NCT02179710
Cystic Fibrosis Treatment Adherence Cayston Proof-of-Concept Pilot Study No drug interventions Not Available Not Available completed NCT04058210
VX-445/TEZ/IVA Expanded Access Program for Cystic Fibrosis (CF) Patients Heterozygous for F508del Mutation and a Minimal Function Mutation (F/MF Genotypes) No drug interventions Not Available Not Available approved_for_marketing NCT01684410
Safety and Tolerability Trial of Inhaled Alpha1-Proteinase Inhibitor (Human), Hydrophobic Chromatography Process (Alpha-1 HC) in Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT00846781
Study 08-114 Open-label Extension of Study 08-110 - A Multi-Center Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis Lung Disease (P08642) No drug interventions treatment 3 terminated NCT01417481
Effect of Glycine in Cystic Fibrosis No drug interventions treatment 2 terminated NCT04320381
Qualitative Understanding of Experiences With the SIMPLIFY Trial No drug interventions Not Available Not Available completed NCT01238081
The Role of Respiratory Viruses in Exacerbations of Cystic Fibrosis in Adults No drug interventions Not Available Not Available completed NCT02194881
Ivacaftor in French Patients With Cystic Fibrosis and a G551D Mutation No drug interventions Not Available Not Available completed NCT02014181
Flaxseed Modulates Inflammation and Oxidative Stress in CF No drug interventions prevention 1 completed NCT03226795
Improving Therapeutic Adherence With a Co-constructed Program Involving Both Patients and Health Care Professionals No drug interventions health_services_research Not Available recruiting NCT02951195
A Study Evaluating the Safety of VX-152 Combination Therapy in Adults With Cystic Fibrosis No drug interventions treatment 2 completed NCT02919995
A Study of RPL554 in Patients With Cystic Fibrosis No drug interventions treatment 2 completed NCT02718495
Study Assessing PTI-428 Safety, Tolerability, and Pharmacokinetics in Subjects With Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT04732195
Pilocarpine Microneedles for Sweat Induction (PMN-SI) No drug interventions diagnostic Not Available completed NCT03527095
A Study to Compare the Pharmacokinetics of Different Oral Formulations of FDL169 in Healthy Subjects No drug interventions treatment 1 completed NCT01746095
Efficacy and Safety Study of AeroVanc for the Treatment of Persistent MRSA Lung Infection in Cystic Fibrosis Patients No drug interventions treatment 2 completed NCT05982795
Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis Microbiome No drug interventions Not Available Not Available recruiting NCT02646995
Lipid Formulation to Increase the Bioavailability of Fatty Acids in Cystic Fibrosis (CF) Patients No drug interventions supportive_care Not Available completed NCT04135495
A Phase 2 Study to Evaluate the Safety, Tolerability, PK and PD of ELX-02 in Cystic Fibrosis Patients With G542X Allele No drug interventions treatment 2 completed NCT02404714
A Multi-Center Study of the CF Quantum® Sweat Test System No drug interventions Not Available Not Available terminated NCT02976714
Identification of Predictive Epigenetic Biomarkers of Lung Disease Severity in Cystic Fibrosis No drug interventions prevention Not Available unknown_status NCT00662714
Early Diagnosis of Diabetes Mellitus in Patients With Cystic Fibrosis No drug interventions treatment 3 completed NCT01537614
Pharmacokinetic Study of Aerosolized Colimycin in Cystic Fibrosis No drug interventions Not Available 1 completed NCT03100214
Effects of an Early Rehabilitation Program During Hospitalization in Patients With Cystic Fibrosis No drug interventions treatment Not Available completed NCT00103714
Study of Denufosol Tetrasodium in Patients With Cystic Fibrosis Lung Disease treatment 2 completed NCT03659214
Impact of the Introduction of ORKAMBI on Anxiety, Depression, Quality of Life and Adherence of Adolescents and Young Adults No drug interventions Not Available Not Available completed NCT00943514
Natural History of Bronchiectasis No drug interventions Not Available Not Available recruiting NCT06147414
Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders No drug interventions Not Available Not Available not_yet_recruiting NCT02110914
A Coaching Intervention to Young Adults With Cystic Fibrosis No drug interventions other Not Available completed NCT06057714
Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT03669614
SAD and MAD of Inhaled AR-501 in Health Adults and P. Aeruginosa Infected Cystic Fibrosis Subjects No drug interventions treatment 1 / 2 recruiting NCT02953314
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of VX-661/Ivacaftor in Pediatric Subjects With Cystic Fibrosis (CF) No drug interventions treatment 3 completed NCT03093714
A Study to Evaluate Safety, PK and PD of FDL169 in Cystic Fibrosis Subjects No drug interventions treatment 1 completed NCT04857814
Integrating Electronic Patient Reported Biometric Measures (ePReBMs) From Wearable Devices in Respiratory Diseases No drug interventions diagnostic Not Available completed NCT06035055
Ceftolozane/Tazobactam Continuous Infusion for Infective Exacerbations of Cystic Fibrosis and Bronchiectasis No drug interventions treatment 4 not_yet_recruiting NCT00806455
Exercise-Induced Bronchospasm in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01755455
Does a Daily Iron Tablet Improve Anemia in Cystic Fibrosis No drug interventions treatment Not Available completed NCT03822455
A Phase 2b Randomised, Placebo Controlled Study of OligoG in Patients With Cystic Fibrosis No drug interventions treatment 2 unknown_status NCT03886350
Implication of UNconventionaL T Lymphocytes in Cystic Fibrosis (UNLOCk) No drug interventions Not Available Not Available completed NCT00129350
Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation No drug interventions treatment 1 unknown_status NCT02286050
Effect of a Nursing Program for Patients With Cystic Fibrosis on Disease Management No drug interventions supportive_care Not Available completed NCT02465450
Safety, Tolerability, Pharmacokinetics, and Efficacy of JBT-101 (Lenabasum) in Cystic Fibrosis No drug interventions treatment 2 completed NCT03264950
Utility of Point Shear-wave Elastography to Assess for Hepatic & Pancreatic Fibrosis in Pediatric CF Patients No drug interventions diagnostic Not Available unknown_status NCT00014950
Benefits and Risks of Newborn Screening for Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT03566550
Gut Imaging for Function & Transit in Cystic Fibrosis Study 1 No drug interventions Not Available Not Available completed NCT01400750
Comparison of 2 Treatment Regimens for Eradication of P Aeruginosa Infection in Children With Cystic Fibrosis No drug interventions treatment 4 completed NCT00609050
Exercise Training Study for Patients With Cystic Fibrosis No drug interventions treatment Not Available completed NCT02717650
The Alfred Step Test Exercise Protocol (A-STEP), for Adults With Cystic Fibrosis. No drug interventions basic_science Not Available recruiting NCT04574050
SELF-BREATHE RCT for Chronic Breathlessness No drug interventions treatment Not Available completed NCT05515250
Neuromodulation for Children With Cystic Fibrosis Experiencing Chronic Abdominal Pain No drug interventions treatment Not Available terminated NCT03045523
A Study to Evaluate GLPG2222 in Ivacaftor-treated Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT04684823
The Impact of Patch Rx Technologies on Adherence to Vitamin and Trikafta Therapies in Patients With Cystic Fibrosis No drug interventions device_feasibility Not Available completed NCT03655223
Early Check: Expanded Screening in Newborns No drug interventions Not Available Not Available enrolling_by_invitation NCT03843723
Cystic Fibrosis and Fit-to-Fly No drug interventions Not Available Not Available completed NCT04877223
Monocytes as Predictors of Cystic Fibrosis-related Bone Disease No drug interventions Not Available Not Available recruiting NCT04961008
Bottle PEP in Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT02730208
A Study to Evaluate the Effect of VX-661 in Combination With Ivacaftor on Chest Imaging Endpoints in Subjects With Cystic Fibrosis, Homozygous for the F508del CFTR Mutation No drug interventions treatment 2 completed NCT02847208
Contraceptive Practices and Cervical Screening in Women With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00590538
Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygotes (for Cystic Fibrosis) No drug interventions basic_science 1 / 2 terminated NCT00164138
Prevalence and Treatment of Urinary Incontinence in Women With Cystic Fibrosis and Chronic Obstructive Pulmonary Disease No drug interventions treatment Not Available completed NCT00308243
Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. treatment 1 completed NCT04803643
Upper Extremity Exercise Capacity, Muscle Oxygenation, Balance in Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02084043
In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation No drug interventions treatment Not Available completed NCT04734743
Muscle Strength, Functional Capacity, Respiratory Function and Quality Of Life In Cystic Fibrosis Patients No drug interventions other Not Available completed NCT02552043
Video Game Exercise Effectiveness of a Domiciliary Pulmonary Rehabilitation Program in Cystic Fibrosis Patients No drug interventions treatment Not Available completed NCT00287443
Metabolic Abnormalities in Hispanic Children With Cystic Fibrosis No drug interventions other Not Available withdrawn NCT01327703
Control of Steatorrhea in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency No drug interventions treatment 4 completed NCT01018303
Safety and Efficacy of an Antioxidant-rich Multivitamin Supplement in Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT02456103
Extension Study of Ataluren in Participants With Nonsense Mutation Cystic Fibrosis No drug interventions treatment 3 terminated NCT05963503
Relationship Between Health Literacy and Physical Activity in Adult Patients With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT01859390
Effects of an Antioxidant-Enriched Multivitamin Supplement on Inflammation and Oxidative Stress in Cystic Fibrosis No drug interventions treatment 2 completed NCT05481190
The Impact Of A Tele-Exercise Program For Children With Cystic Fibrosis During The Covid-19 Pandemic On Quality Of Life No drug interventions supportive_care Not Available completed NCT06197490
Renal Impact of KAFTRIO in Mucoviscidose Population No drug interventions Not Available Not Available recruiting NCT03051490
RESULT: Reliable, Emergent Solution Using Liprotamase Treatment No drug interventions treatment 3 unknown_status NCT01707290
Rollover Study of Ivacaftor in Subjects With Cystic Fibrosis and a Non G551D CFTR Mutation No drug interventions treatment 3 completed NCT01347190
Safety and Tolerability Study of Liquid Alpha1 Proteinase Inhibitor (API) in Subjects With Cystic Fibrosis No drug interventions treatment 1 completed NCT00157690
Study of Alendronate to Prevent and Treat Osteoporosis in Cystic Fibrosis Patients treatment 4 completed NCT04624490
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease No drug interventions diagnostic 1 recruiting NCT03489590
19F MRI to Evaluate Regional Ventilation in Healthy Subjects and Subjects With Cystic Fibrosis No drug interventions other 0 completed NCT00503490
Safety, Pharmacokinetic and Pharmacodynamic Study of MP-376 in Patients With Cystic Fibrosis No drug interventions treatment 1 completed NCT01241890
Prevention of CF Exacerbation in Childhood: PREVEC Study No drug interventions Not Available Not Available completed NCT04075864
Feasibility of a New Model for Exercise Prescription in Cystic Fibrosis No drug interventions other Not Available recruiting NCT00585364
Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA No drug interventions Not Available Not Available completed NCT02141464
Energy Balance and Weight Gain With Ivacaftor Treatment No drug interventions Not Available Not Available completed NCT04923464
A Decentralized Study to Evaluate Physical Activity and Cough Frequency Using Wearable Technology in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00716664
Do Musculoskeletal Techniques Improve Forced Expiratory Volume in One Second in Adults With Cystic Fibrosis? No drug interventions treatment Not Available completed NCT05802264
Study to Assess Amphotericin B Cystetic for Inhalation (ABCI) Doses in Healthy Volunteers & People With Cystic Fibrosis No drug interventions treatment 1 recruiting NCT00431964
Effect of Azithromycin on Lung Function in 6-18 Year-olds With Cystic Fibrosis (CF) Not Infected With P. Aeruginosa No drug interventions treatment 4 completed NCT02823964
EASY: Extended Access to Sollpura Over Years No drug interventions treatment 4 completed NCT05561764
Imipenem/Cilastatin/Relebactam Pharmacokinetics, Safety, and Outcomes in Adults and Adolescents With Cystic Fibrosis No drug interventions other 4 recruiting NCT04496921
Vitamin K Supplementation to Reduce Deficiencies in Adults With Cystic Fibrosis No drug interventions prevention Not Available withdrawn NCT02715921
Impact of Telerehabilitation Training on Pediatric Cystic Fibrosis Patients: An Exploratory Study No drug interventions other Not Available completed NCT01488721
Clinical Evaluation of NeoPlex4 Assay and NeoPlex System No drug interventions Not Available Not Available completed NCT00164021
The Prevalence and Significance of Gastro-oesophageal Reflux in Cystic Fibrosis Before and After Lung Transplantation No drug interventions Not Available Not Available unknown_status NCT02866721
Safety and Tolerability Study of Allogeneic Mesenchymal Stem Cell Infusion in Adults With Cystic Fibrosis No drug interventions treatment 1 completed NCT05822102
Simultaneous quanTification of Elexacaftor/tezAcaftor/Ivacaftor Via Reverse Phase High Performance liquiD chromatographY No drug interventions Not Available Not Available enrolling_by_invitation NCT00537602
Miglustat / OGT 918 in the Treatment of Cystic Fibrosis No drug interventions treatment 2 terminated NCT06045702
Establishment of a Primary Epididymal Cell Model From Epididymal Samples to Study CFTR Gene Regulation No drug interventions Not Available Not Available not_yet_recruiting NCT06515002
A Study to Test How Well BI 3720931 is Tolerated and Whether it Improves Lung Function in People With Cystic Fibrosis (Lenticlair™ 1) No drug interventions treatment 1 / 2 not_yet_recruiting NCT04056702
Impact of Triple Combination CFTR Therapy on Sinus Disease. No drug interventions Not Available Not Available unknown_status NCT00966602
Drug-Drug Interaction Study of VX-809 and VX-770 in Healthy Subjects No drug interventions treatment 1 completed NCT06327802
Improving the Well-being of Caregivers of Cystic Fibrosis Patients During Physiotherapy Treatment No drug interventions Not Available Not Available recruiting NCT00806884
Do Physiotherapy Techniques Improve Posture During Admission for a Chest Infection in Adults With Cystic Fibrosis? No drug interventions health_services_research Not Available completed NCT04696484
Feasibility of a Goal-based Agenda Setting Intervention No drug interventions health_services_research Not Available completed NCT01746784
Safety and Pharmacokinetic Study of N6022 in Subjects With Cystic Fibrosis Homozygous for the F508del-CFTR Mutation No drug interventions treatment 1 completed NCT04735679
Characterization of Pulmonary Microbiome in Cystic Fibrosis Patients No drug interventions Not Available Not Available unknown_status NCT00534079
Nasal Inhalation of Pulmozyme in Patients With Cystic Fibrosis and Chronic Rhinosinusitis No drug interventions treatment 3 completed NCT02198079
A Prospective, Multicenter, Collaborative Study to Determine the Prevalence of Nontuberculous Mycobacteria (NTM) in Pediatric Patients With Cystic Fibrosis in Florida No drug interventions Not Available Not Available completed NCT00004779
Phase I Pilot Study of Ad5-CB-CFTR, an Adenovirus Vector Containing the Cystic Fibrosis Transmembrane Conductance Regulator Gene, in Patients With Cystic Fibrosis No drug interventions treatment 1 completed NCT04623879
Real Life Evaluation of the Multi-organ Effects of Lumacaftor/Ivacaftor on F508del Homozygous Cystic Fibrosis Patients. No drug interventions Not Available Not Available completed NCT02790879
Transition From Pediatric to Adult Cystic Fibrosis Care Center No drug interventions Not Available Not Available unknown_status NCT02832479
Costs of Care and Adherence to Treatment for Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01546779
The Use of Visual Feedback in Airway Clearance No drug interventions treatment Not Available completed NCT02003079
Evaluating the Impact of Chronic Rhinosinusitis on the Health-Related Quality of Life Among Adults With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00803179
Growth Hormone Therapy for Wasting in Cystic Fibrosis No drug interventions treatment 1 terminated NCT03691779
Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age No drug interventions treatment 3 completed NCT02606487
Hyperpolarized Xenon MRI in Cystic Fibrosis Pulmonary Exacerbations No drug interventions Not Available Not Available completed NCT06072287
The Living With a Long-Term Condition Study No drug interventions Not Available Not Available recruiting NCT01983787
Pharmacokinetics of Piperacillin, Given as Continuous Infusion to Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00004287
Phase I Study of the Third Generation Adenovirus H5.001CBCFTR in Patients With Cystic Fibrosis No drug interventions treatment 1 completed NCT02212587
Tobramycin Inhalation Powder (TIP) in Cystic Fibrosis Patients Infected With Burkholderia Cepacia Complex No drug interventions treatment 1 completed NCT04476433
Intervention in Chronic Pediatric Patients and Their Families. No drug interventions prevention Not Available completed NCT00004533
Phase I Randomized Study of Adeno-Associated Virus-CFTR Vector in Patients With Cystic Fibrosis No drug interventions treatment 1 completed NCT04137133
Patienthèque of Finisterian (South of Brittany) Children With Cystic Fibrosis in the Time of Precision Medicine No drug interventions diagnostic Not Available recruiting NCT03224351
A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT02342951
Evaluation of the Lung Clearance Index No drug interventions screening Not Available completed NCT00688051
Changes in Adherence After Playing "My Life With CF" Game No drug interventions treatment Not Available completed NCT03145051
Efficacy of Nasal Irrigation With Respimer® Netiflow® vs Saline Among Patients With Cystic Fibrosis and Chronic Rhinosinusitis No drug interventions treatment Not Available unknown_status NCT03069651
Virtual Care in CF (VIRTUAL-CF) Study No drug interventions supportive_care Not Available unknown_status NCT06122051
Dynamic Chest X-ray With Simultaneous Spirometry No drug interventions Not Available Not Available not_yet_recruiting NCT04058353
A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes) No drug interventions treatment 3 completed NCT04519853
A Pilot Study of a Low Glycemic Load Diet in Adults With Cystic Fibrosis No drug interventions treatment Not Available completed NCT02445053
Observational Study of Outcomes in Cystic Fibrosis Patients With Selected Gating Mutations on a CFTR Allele (The VOCAL Study) No drug interventions Not Available Not Available completed NCT01035853
Sino-nasal Inhalation of Colistin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization No drug interventions treatment 2 completed NCT03066453
Evaluation of Short Antibiotic Combination Courses Followed by Aerosols in Cystic Fibrosis No drug interventions treatment 3 terminated NCT01229553
Effect of Topical and Systemic Decolonization of Staphylococcus Aureus (SA) in Pediatric Cystic Fibrosis (CF) Patients No drug interventions treatment Not Available withdrawn NCT04010253
Impact of Bronchial Drainage Technique by the Medical Device Simeox® on Respiratory Function and Symptoms in Adult Patients With Cystic Fibrosis No drug interventions treatment Not Available unknown_status NCT04378153
Impact of Discontinuing Chronic Therapies in People With Cystic Fibrosis on Highly Effective CFTR Modulator Therapy No drug interventions other Not Available completed NCT01319253
A Comparator Study Evaluating Microbiological Resistance and Effects of Alternating Inhaled Antibiotic Therapies No drug interventions Not Available Not Available completed NCT02134353
A Safety and Efficacy Trial of Inhaled Mannitol in Adult Cystic Fibrosis Subjects No drug interventions treatment 3 completed NCT00846053
FDG-PET Imaging in Young Cystic Fibrosis Patients No drug interventions diagnostic Not Available completed NCT03797677
MN4000 for Treatment of CF and MND Patients in the Home Setting No drug interventions treatment Not Available completed NCT00779077
Cystic Fibrosis (CF) Flow Rates Study No drug interventions Not Available Not Available completed NCT04549077
Pulmonary Vascular Disease in CF No drug interventions Not Available Not Available recruiting NCT02301377
Exploring Novel Interventions to Improve Adherence in Children With Cystic Fibrosis No drug interventions health_services_research Not Available completed NCT00763477
Ghrelin in Cystic Fibrosis No drug interventions health_services_research Not Available unknown_status NCT02054377
Cystic Fibrosis- Children and Adults Tai Chi Study No drug interventions treatment Not Available completed NCT05010577
Nebulized Bacteriophage Therapy in Cystic Fibrosis Patients With Chronic Pseudomonas Aeruginosa Pulmonary Infection No drug interventions treatment 1 / 2 active_not_recruiting NCT01916577
Autologous CD117+ Progenitor Cell Mobilization for Lung Transplantation No drug interventions treatment 1 completed NCT05867147
An Electrocardiogram Study to Evaluate the Effect of Vanzacaftor on the QT/QTc Interval in Healthy Participants No drug interventions treatment 1 completed NCT00924547
Oral Docosahexanoic Acid Supplementation in Cystic Fibrosis No drug interventions treatment 2 completed NCT04038047
A Prospective Study to Evaluate Biological and Clinical Effects of Significantly Corrected CFTR Function No drug interventions Not Available Not Available active_not_recruiting NCT00751647
Cystic Fibrosis Core Strengthening and Respiratory Exercise Program No drug interventions supportive_care 2 completed NCT00056147
Study of INS37217 Inhalation Solution in Mild to Moderate Cystic Fibrosis Lung Disease treatment 2 completed NCT01705145
Study of Ivacaftor in Cystic Fibrosis Subjects 2 Through 5 Years of Age With a CFTR Gating Mutation No drug interventions treatment 3 completed NCT01706445
Combined Inspiratory Muscle and 'Whole Muscle' Training in Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00399945
Tobramycin Inhalation Solution Administered by eFlow Rapid Nebulizer: Scintigraphy Study No drug interventions treatment 1 completed NCT00812045
Study to Assess Efficacy of AZD1236 in Patients With Cystic Fibrosis No drug interventions treatment 2 withdrawn NCT05986045
ENHANCE- Establishing Natural History in an Advanced New CF Care Era No drug interventions Not Available Not Available not_yet_recruiting NCT02343445
Clearing Lungs With Epithelial Sodium Channel (ENaC) Inhibition in Cystic Fibrosis (CF) No drug interventions treatment 2 completed NCT03850145
Educational Program Through Video Conference for Inhaled Therapies in Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT05723445
The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes No drug interventions treatment Not Available recruiting NCT02358798
Respiratory Function at Preschool Age of Children Detected of Cystic Fibrosis in Neonatal Period No drug interventions other Not Available completed NCT04696198
Thoracic Mobility in Cystic Fibrosis Care No drug interventions treatment Not Available completed NCT02279498
SOLUTION: Study of Oral Liprotamase Unit-Matched Therapy Of Non-Porcine Origin in Patients With Cystic Fibrosis No drug interventions treatment 3 completed NCT03045198
Effect of Azithromycin on Fatty Acids in CF No drug interventions treatment 4 unknown_status NCT02934698
An Efficacy and Safety Study of Ivacaftor in Patients With Cystic Fibrosis and Two Splicing Mutations No drug interventions treatment 3 completed NCT02748798
Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders No drug interventions diagnostic 0 recruiting NCT00908505
Comparison Between RTX (Biphasic Cuirass Ventilator) and Physiotherapy in Cystic Fibrosis Patients No drug interventions treatment Not Available unknown_status NCT00004705
Study of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis treatment Not Available completed NCT05225805
Study to Assess the Safety and PK of Oral and IV Xenleta in Adults With Cystic Fibrosis No drug interventions other 1 completed NCT01899105
A Phase 1 Study to Investigate the Food Effect of Lumacaftor in Combination With Ivacaftor No drug interventions Not Available 1 completed NCT02767297
Bioavailability and Pharmacokinetics Study of FDL169 in Healthy Subjects and Subjects With Cystic Fibrosis No drug interventions Not Available 1 / 2 completed NCT04814797
Use of Capnography for the Follow-up of Cystic Fibrosis Children No drug interventions Not Available Not Available unknown_status NCT03518697
Effects of an Individualized Exercise Program on Health-related and Skill/Performance-related fitness in CF. No drug interventions treatment Not Available completed NCT02113397
Evaluation of Inhaled Antibiotics on Bacterial Diversity and Richness in the Cystic Fibrosis Lung No drug interventions Not Available Not Available terminated NCT01822197
Pilot Trial of Phototherapy for Acute Depression in Hospitalized Cystic Fibrosis Patients No drug interventions treatment Not Available completed NCT02950883
Saline Hypertonic in Preschoolers + CT No drug interventions treatment 2 / 3 completed NCT01223183
Absorptive Clearance After Inhaled Osmotics in Cystic Fibrosis No drug interventions basic_science 1 completed NCT04259983
Investigation of Relationship Between Vascular Functions, Exercise Capacity, and Respiratory Functions in CF No drug interventions Not Available Not Available completed NCT00157183
Non-invasive Ventilation and Oxygen Therapy in Cystic Fibrosis Patients With Nocturnal Oxygen Desaturation No drug interventions treatment 1 / 2 completed NCT01111383
A Single Arm 48-Week Follow-on Safety Study to a Core Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI® No drug interventions treatment 3 completed NCT03323983
Exploratory Study on Link Between Dynamic Hyperinflation and Lung Clearance Index in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00311883
Hydroxychloroquine in Cystic Fibrosis treatment 1 completed NCT02958683
Chest Wall Motion Analysis in Disease No drug interventions Not Available Not Available completed NCT01737983
Effect of Lactobacillus Reuteri in Cystic Fibrosis No drug interventions treatment 4 completed NCT02372383
Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis No drug interventions treatment Not Available completed NCT00743483
Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency No drug interventions treatment 2 completed NCT00027183
Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa No drug interventions Not Available Not Available completed NCT06350461
Impact of Discontinuing Hypertonic Saline in People With CF on Highly Effective CFTR Modulators- A SIMPLIFY Sub-Study No drug interventions other Not Available completed NCT04362761
A Study Evaluating the Long-Term Safety of Elexacaftor Combination Therapy No drug interventions treatment 3 completed NCT04397861
T Cell Memory Fuels the Innate Response in Chronic CF Lung Disease No drug interventions Not Available Not Available completed NCT00804661
Sleep in Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT04461561
Using NPT to Evaluate Providing PPC as ELNEC-PPC WBT for Nurses No drug interventions other Not Available unknown_status NCT01446861
Exocrine Pancreatic Function Testing in Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT06371261
Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT03587961
Personalized Theratyping Trial No drug interventions treatment 0 recruiting NCT03304028
MUCOviscidose EXacerbation Outils Connectés Education Thérapeutique No drug interventions prevention Not Available terminated NCT03840928
PatientSpot Formerly Known as ArthritisPower No drug interventions Not Available Not Available recruiting NCT04463628
Impacts of the Covid-19 Epidemic and Associated Lockdown Measures on the Management, Health and Behaviors of Cystic Fibrosis Patients During the 2020 Epidemic No drug interventions Not Available Not Available completed NCT01991028
A Study to Investigate Lung Deposition of Radiolabelled OligoG No drug interventions basic_science 2 completed NCT03647228
A Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of IONIS-ENaCRx in Healthy Volunteers and Patients With Cystic Fibrosis No drug interventions treatment 1 completed NCT04613128
The PROMISE Pediatric Study 6 to 11 Years Old No drug interventions Not Available Not Available active_not_recruiting NCT00004428
Phase I Randomized Study of CPX for the Treatment of Adult Patients With Mild Cystic Fibrosis No drug interventions treatment 1 completed NCT05719311
Study to Assess an Enteric Microgranule Formulation of Adrulipase in Patients With Cystic Fibrosis No drug interventions treatment 2 completed NCT01225211
Study of VX-809 Alone and in Combination With VX-770 in Cystic Fibrosis (CF) Patients Homozygous or Heterozygous for the F508del-CFTR Mutation No drug interventions treatment 2 completed NCT03801993
Multicenter Study of Patient-reported Gastrointestinal Symptoms in People With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02564393
Induction of Neutrophilic Traps ( NETs ) by the Environment and Infectious Inflammatory Lung Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00983671
Standardisation of Measurements in Exhaled Breath and Exhaled Breath Condensate. No drug interventions Not Available Not Available unknown_status NCT03041571
Impact of Early Implementation of Narrative Medicine Techniques on Patient Centered Attitudes of Medical Students No drug interventions Not Available Not Available withdrawn NCT00721071
Utility of Induced Sputum Using Hypertonic Saline to Evaluate Infection and Inflammation in Cystic Fibrosis No drug interventions diagnostic 2 completed NCT00685971
Cholecalciferol for Vitamin D in Adult Cystic Fibrosis (CF) Patients No drug interventions treatment Not Available completed NCT04016571
Parameters to Assess Response to Intra-Venous Antibiotic Treatment for Pulmonary Exacerbations in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT05455671
Real-Time Assessment of Lung Structure and Function in Children and Young Adults With CF Using Electrical Impedance Tomography No drug interventions Not Available Not Available recruiting NCT02209571
Breath Analysis in in Adults With Cystic Fibrosis (CF) No drug interventions basic_science Not Available completed NCT00760071
Magnetic Resonance Imaging (MRI) for Early Diagnosis of Cystic Fibrosis (CF) No drug interventions Not Available Not Available completed NCT00758771
Using Rheological Methods to Characterize Cystic Fibrosis (CF) Sputum and the Effects of Mucoactive Agents No drug interventions Not Available Not Available completed NCT00351078
PTC124 for the Treatment of Cystic Fibrosis No drug interventions treatment 2 completed NCT01844778
Ease of Use and Microbial Contamination of Tobramycin Inhalation Powder (TIP) Versus Nebulised Tobramycin Inhalation Solution (TIS) and Nebulised Colistimethate (COLI) No drug interventions treatment 4 completed NCT01232478
I Change Adherence & Raise Expectations No drug interventions health_services_research 3 completed NCT01309178
Anti-inflammatory Pulmonal Therapy of Cystic Fibrosis (CF) Patients With Amitriptyline and Placebo No drug interventions treatment 2 unknown_status NCT00208078
Effect of Non-Invasive Ventilation in Cystic Fibrosis Patient With Chronic Respiratory Failure. No drug interventions treatment 4 terminated NCT03206788
Losartan and Inflammation in Cystic Fibrosis No drug interventions treatment 2 terminated NCT02538588
Comparison of Amikacin Lung Delivery With Two Nebulizers No drug interventions treatment Not Available unknown_status NCT00645788
Study to Evaluate the Safety and Efficacy of Ciprofloxacin (Inhaled) in Patients With Cystic Fibrosis No drug interventions treatment 2 completed NCT02955888
Study of Safety, Tolerability & Efficacy in Cystic Fibrosis Patients With Abnormal Glucose Tolerance No drug interventions treatment 2 terminated NCT01200888
Controlled Ventilation CT in CF Infants No drug interventions Not Available Not Available terminated NCT03969888
A Phase 2 Study of ABBV-3067 Alone and in Combination With ABBV-2222 No drug interventions treatment 2 completed NCT05948488
Psychological Study in Children With Mucoviscidosis No drug interventions Not Available Not Available completed NCT02227888
PK Study of N91115 in Cystic Fibrosis Patients No drug interventions treatment 1 completed NCT00782288
Phase II Study of Digitoxin to Treat Cystic Fibrosis No drug interventions treatment 2 completed NCT02443688
EMPIRE CF: A Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of CTX-4430 in Adult Cystic Fibrosis (CF) Patients No drug interventions treatment 2 completed NCT05896488
Sweat Response, Sweat Composition and Thermoregulatory Response to Exercise in Heat in Adults With Cystic Fibrosis on Modulator Therapy. No drug interventions Not Available Not Available recruiting NCT02907788
Inflammatory Markers in Broncho-alveolar Lavage Fluid as Risk Factors for Lung Disease in Infants With Cystic Fibrosis: the I-BALL Study No drug interventions Not Available Not Available completed NCT01144507
Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01131507
PR-018: An Open-Label, Safety Extension of Study PR-011 No drug interventions treatment 4 completed NCT03913507
Efficacy of a New Sweat Collection Support: Impact on Neonatal Screening and Early Treatment of Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT02073409
PREDICT Trial: PRospective Evaluation of NTM Disease In CysTic Fibrosis No drug interventions Not Available Not Available enrolling_by_invitation NCT02709109
A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation No drug interventions treatment 2 completed NCT05857709
Fitness, Body Composition, Physical Activity and Sleep Patterns in People With Cystic Fibrosis on Modulator Therapy. No drug interventions Not Available Not Available recruiting NCT04397809
Utility of CD64 and TLR2 Assays to Diagnose Acute Pulmonary Exacerbations in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT04297709
Study of Urinary Predictors of Exacerbations by Biomarkers in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02918409
IV Colistin for Pulmonary Exacerbations: Improving Safety and Efficacy No drug interventions treatment 4 completed NCT03420209
The Effect of Proprioceptive Neuromuscular Facilitation (PNF) Technique for Children With Chronic Pulmonary Diseases. No drug interventions treatment Not Available completed NCT06238856
Single Dose Escalation Study of TR02 (Sustained Lipid Inhalation Technology [SLIT™] Amikacin) in Participants With Cystic Fibrosis (CF) Having Chronic Infections of Pseudomonas Aeruginosa No drug interventions treatment 1 completed NCT05639556
Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF No drug interventions Not Available Not Available recruiting NCT03462056
Ready to Use Therapeutic Food (RUTF) to Promote Growth in Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT05934656
Understanding Gut Symptoms in People With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT05135156
Lung Transplant READY Pilot Study No drug interventions other Not Available completed NCT03628456
Effect of HFCWO Vests on Spirometry Measurements No drug interventions treatment Not Available completed NCT03485456
DPI-Tobra-Kind Cyclops® in Children With Cystic Fibrosis No drug interventions treatment 1 / 2 unknown_status NCT00015756
Tissue Collection From People With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00251056
Mannitol Dose Response Study in Cystic Fibrosis No drug interventions treatment 2 completed NCT05581056
Evaluation of the Evolution of Quality of Life in Relation to Naso-sinus Symptomatology Under Treatment With CFTE Modulators in Children Aged 6 to 11 Years With Cystic Fibrosis With Compatible Mutation No drug interventions Not Available Not Available active_not_recruiting NCT00333385
Continuous Versus Short Infusions of Ceftazidime in Cystic Fibrosis No drug interventions treatment 4 terminated NCT02449785
Assessment of Cystic Fibrosis Lung Involvement With UTE Pulse Sequences No drug interventions supportive_care Not Available completed NCT04545515
A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (CF) Particpants 6 Years and Older and F/MF Genotypes No drug interventions treatment 3 completed NCT01702415
Zoledronic Acid in Cystic Fibrosis No drug interventions treatment 4 withdrawn NCT01910415
Phase 1, QT/QTC Interval Study in Healthy Subjects No drug interventions treatment 1 completed NCT05101915
Study of a Nebulised Nitric Oxide Generating Solution in Patients With Mycobacterium Abscessus No drug interventions treatment 2 terminated NCT01731015
Imaging Lung Function Using Oxygen Enhanced MRI No drug interventions diagnostic 1 completed NCT01155115
Inflammatory and Microbiologic Markers in Sputum: Comparing Cystic Fibrosis With Primary Ciliary Dyskinesia No drug interventions treatment Not Available completed NCT01576315
ATCF (Azole Therapy in Cystic Fibrosis) No drug interventions treatment 2 completed NCT00034515
A Study in Adult and Pediatric Patients With Cystic Fibrosis treatment 1 / 2 completed NCT05937815
Intestine-lung Axis of Cystic Fibrosis Patients Treated With the Combination Elexacaftor/Tezacaftor/Ivacaftor No drug interventions diagnostic Not Available recruiting NCT02912637
Hyperpolarized Xenon Imaging in Patients With Cystic Fibrosis No drug interventions Not Available Not Available suspended NCT03601637
Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Participants 1 to Less Than 2 Years of Age With Cystic Fibrosis, Homozygous for F508del No drug interventions treatment 3 completed NCT00499837
Phase II Study of the Safety and Efficacy of Inhaled Alpha-1 Antitrypsin (AAT ) in Cystic Fibrosis Patients No drug interventions treatment 2 completed NCT05504837
A Study Assessing KB407 for the Treatment of Cystic Fibrosis No drug interventions treatment 1 recruiting NCT02769637
Effect of Acid Blockade on Microbiota and Inflammation in Cystic Fibrosis (CF) No drug interventions Not Available Not Available terminated NCT00757237
Aztreonam for Inhalation Solution vs Tobramycin Inhalation Solution in Patients With Cystic Fibrosis & Pseudomonas Aeruginosa No drug interventions treatment 3 completed NCT02433132
Cystic Fibrosis Diagnosis by Analyzing Nasal Brushing No drug interventions diagnostic Not Available unknown_status NCT00001532
Role of Genetic Factors in the Development of Lung Disease No drug interventions Not Available Not Available recruiting NCT00596232
Investigating Mucinase Activity in Airway Disease No drug interventions Not Available Not Available completed NCT00750932
Biodistribution of Neutrophile Proteases in the Sputum of Patients Affected by Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03181932
AeroVanc in the Treatment of Methicillin-resistant Staphylococcus Aureus Infection in Patients With Cystic Fibrosis No drug interventions treatment 3 completed NCT05941832
ANNE Sensor Monitoring in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT05801952
PEP and OPEP Devices in Cystic Fibrosis No drug interventions treatment Not Available recruiting NCT03931252
Thermic Effect of Feeding in Cystic Fibrosis No drug interventions basic_science Not Available withdrawn NCT06217952
Safety, Tolerability, and Pharmacokinetics of SPL84 in Healthy Volunteers No drug interventions treatment 1 completed NCT00577252
Coping Compliance and Adjustment in Adolescents With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03820752
Vaccination Coverage and Level of Protection in Patients at Risk No drug interventions Not Available Not Available completed NCT04735952
Improving P. Aeruginosa Detection With Breath-based Diagnostics (IMPACT-Breath) No drug interventions Not Available Not Available recruiting NCT00163852
Treatment of Metabolic Alkalosis in Acute Exacerbations of Cystic Fibrosis No drug interventions treatment 2 / 3 unknown_status NCT02323100
Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis) No drug interventions treatment 1 / 2 terminated NCT00737100
Safety and Efficacy of 12-wk Treatment With Two Doses of Tiotropium Respimat in Cystic Fibrosis No drug interventions treatment 2 completed NCT04891159
Training in Shared Decision-making of Cystic Fibrosis Centers Competences in the Treatment of CF Related Diabetes in Adult Patients No drug interventions Not Available Not Available unknown_status NCT01429259
Population Pharmacokinetics of Prolonged Infusion Meropenem in Cystic Fibrosis (CF) Children No drug interventions treatment 4 completed NCT00221559
Serum Zn Status of Patients With Cystic Fibrosis at Diagnosis and One Year Later, Compared to a Healthy Control Group No drug interventions Not Available Not Available completed NCT05253859
CFTR Modulators and Gastrointestinal Complications No drug interventions Not Available Not Available completed NCT03273959
Program Of Exercises During The Hospitalization Of Children And Adolescents With Cystic Fibrosis No drug interventions treatment Not Available unknown_status NCT02354859
A Phase 2 IV Gallium Study for Patients With Cystic Fibrosis (IGNITE Study) No drug interventions treatment 2 completed NCT02107859
Study of Ataluren (PTC124) in Cystic Fibrosis No drug interventions treatment 3 terminated NCT03524859
Evaluation of Sit-to-stand Test in Patients With Cystic Fibrosis and Matched Controls. No drug interventions Not Available Not Available completed NCT05535959
A Study to Evaluate the Relative Bioavailability of a Fixed-dose Combination Tablet of VX-121/Tezacaftor/Deutivacaftor No drug interventions treatment 1 completed NCT00663975
Open Label Safety Study of DCI-1020 in Pediatric Cystic Fibrosis (CF) Patients No drug interventions treatment Not Available withdrawn NCT01915875
Impact of Global Care of the Pain at Chronic Painful Patients Affected by Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT04687475
Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis No drug interventions prevention Not Available recruiting NCT04541875
Medication Adherence and Non-adherence in Adults With Rare Disease No drug interventions Not Available Not Available withdrawn NCT02538575
6 Minute Walk Test in Cystic Fibrosis No drug interventions other Not Available completed NCT06302270
CFTR Modulators in Pregnancy and Postpartum No drug interventions Not Available Not Available recruiting NCT02823470
A Pilot Study to Evaluate the Use of Smart Adherence Technology to Measure Lumacaftor/Ivacaftor Adherence in CF Subjects Homozygous for the F508del CFTR Mutation No drug interventions treatment 4 terminated NCT02480270
Outpatient Antibiotic Treatment for a Cystic Fibrosis Pulmonary Exacerbation No drug interventions Not Available Not Available completed NCT01288170
Pharmacokinetic Bioequivalence Study of Nebcinal® 150mg/3ml Administered by Aeroneb® Idehaler® Versus Tobi® 300mg/5ml Administered by Pari LC Plus® No drug interventions treatment Not Available unknown_status NCT01614470
Study of Ivacaftor in Subjects With Cystic Fibrosis (CF) Who Have a Non-G551D CF Transmembrane Conductance Regulator (CFTR) Gating Mutation No drug interventions treatment 3 completed NCT04259970
Hyperpolarized Imaging for New Treatments No drug interventions diagnostic 4 active_not_recruiting NCT04335370
Pharmacokinetics of Polymyxin B in Adult Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00043342
Study of Interferon Gamma-1b by Injection for the Treatment of Patients With Cystic Fibrosis treatment 1 / 2 completed NCT01180842
Treatment of Anxiety/Depression and Pain Through Relaxation Yoga for Patient With Cystic Fibrosis (CF) No drug interventions treatment 2 completed NCT00079742
A Study to Evaluate Nutropin AQ for the Treatment of Growth Restriction in Children With Cystic Fibrosis treatment 2 completed NCT01241942
Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability No drug interventions device_feasibility Not Available terminated NCT01759342
Comprehensive Exercise Training Program During Hospitalization for an Acute CF Exacerbation No drug interventions treatment Not Available completed NCT03474042
GLPG2737 on Top of Orkambi in Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT03905642
Study of Dose Escalation of Liposomal Amikacin for Inhalation (ARIKAYCE™) - Extension Phase No drug interventions treatment 2 completed NCT03644199
Development of Diabetes in Adults With Cystic Fibrosis (CF) No drug interventions other Not Available withdrawn NCT04010799
A Clinical Study to Investigate Safety, Tolerability and Distribution of CHF 6333 After One or After Repeated Inhalation in Patients With Cystic Fibrosis (CF) and in Patients With Non Cystic Fibrosis (NCFB) Bronchiectasis No drug interventions treatment 1 completed NCT04249999
ActivOnline: Physical Activity in Cystic Fibrosis Trial UK No drug interventions treatment Not Available unknown_status NCT00577499
Effect of Lubiprostone on Nutritional Status and Pulmonary Function in Adults With Cystic Fibrosis No drug interventions Not Available Not Available terminated NCT00004806
Phase I Study of Liposome-Mediated Gene Transfer in Patients With Cystic Fibrosis No drug interventions treatment 1 completed NCT04743206
Airway Clearance for Pediatric and Adult Cystic Fibrosis Patients Using a Portable Intra-Pulmonary Percussion Device No drug interventions other Not Available completed NCT04043806
A Study Evaluating the Long-term Safety of VX-445 Combination Therapy No drug interventions treatment 3 completed NCT06478706
A Two-Part Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Repeat Doses of Inhaled ETD001 in People With Cystic Fibrosis No drug interventions treatment 2 recruiting NCT00311506
A Study to Determine the Variability of a 6-Minute Walk Test in Cystic Fibrosis Subjects With Advanced Lung Disease No drug interventions Not Available Not Available completed NCT05012306
Covid-19 Antibody Responses in Cystic Fibrosis No drug interventions Not Available Not Available active_not_recruiting NCT01818206
Bacteriophage Effects on Pseudomonas Aeruginosa No drug interventions basic_science Not Available completed NCT01100606
A Study to Evaluate the Mode of Administration and Safety of EUR-1008 (APT-1008) in Infants 1 to 12 Months of Age No drug interventions treatment 4 completed NCT06030206
Lung Transplant READY CF 2: A Multi-site RCT No drug interventions other Not Available recruiting NCT06460506
Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older No drug interventions treatment 3 not_yet_recruiting NCT02994706
A Study of Home Monitoring in Adults With Cystic Fibrosis (HOMECF) No drug interventions health_services_research Not Available completed NCT01710449
Evaluation of Regional Ventilation Using 19F MRI of Inert Perfluorinated Gases Mixed With Oxygen No drug interventions diagnostic 1 completed NCT00345449
Evaluation of a Decision Aid for Adult Cystic Fibrosis Patients Considering Bilateral Lung Transplantation No drug interventions Not Available Not Available completed NCT03447249
A Phase 3 Study of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF) No drug interventions treatment 3 completed NCT04742049
The Effects of Telerehabilitation on Muscle Function, Physical Activity and Sleep in Cystic Fibrosis During Pandemic No drug interventions treatment Not Available completed NCT03119649
A Study to Evaluate Multiple Doses of GLPG2222 in Adult Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT01793649
A Phase 1 Study to Characterize the Effect of GS-5737 Enhancement of Mucociliary Clearance (MCC) in Healthy Subjects No drug interventions treatment 1 terminated NCT03655249
Effects of AD on VI in Patients With CF No drug interventions treatment Not Available recruiting NCT06350149
A Pilot and Feasibility Study to Evaluate High vs Low Glycemic Index Mixed Meal Tolerance Test in Adolescents and Young Adults With Cystic Fibrosis No drug interventions other Not Available recruiting NCT01533636
CF And Effects of Drugs Mixed Ex Vivo With Sputum for Mucolytic Treatment No drug interventions Not Available Not Available recruiting NCT00420836
Tobramycin Administered by eFlow Rapid Nebulizer: Pharmacokinetic Study No drug interventions treatment 1 completed NCT03486236
A Study Evaluating Safety and Pharmacokinetics of VX-440 in Combination With Tezacaftor/Ivacaftor in Healthy Adult Subjects No drug interventions treatment 1 completed NCT02840136
LC-MS/MS Based Method Development for the Monitoring of Antibiotic Concentrations in Sputum of Cystic Fibrosis Patients No drug interventions basic_science Not Available terminated NCT01150136
Choline Nutritional Status Of Children With Cystic Fibrosis X-Sectional Study No drug interventions Not Available Not Available completed NCT04274413
CFTR Related Pancreatitis Study No drug interventions diagnostic Not Available withdrawn NCT03771313
Pharmacokinetic and Pharmacodynamic Analysis of Ceftaroline in Children and Adolescents With Cystic Fibrosis No drug interventions treatment 4 active_not_recruiting NCT04161313
Respiratory Function, Exercise Capacity and Peripheral Muscle Strength Among Patients With CF, PCD and Healthy Children No drug interventions Not Available Not Available completed NCT03229213
Interactive Video Game Responses in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT04451213
Magnetic Resonance Imaging and Neuro-Psychological Testing In Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT00274313
Safety Study of Inhaled 552-02 in Cystic Fibrosis Patients No drug interventions treatment 1 / 2 completed NCT05267418
Effects of Automated Oxygen Titration Alone or With High Flow Nasal Therapy on Dyspnea and Exercise Tolerance No drug interventions supportive_care Not Available terminated NCT00762918
Vitamin D3 for the Treatment of Low Vitamin D in Cystic Fibrosis No drug interventions treatment 3 withdrawn NCT00954018
Microbial Community Composition and Metabolism in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT04798118
Role of Toilet Bronchoscopy in RICU No drug interventions supportive_care Not Available unknown_status NCT05740618
Inhaled Mannitol on Mucociliary Clearance in Moderate to Severe Cystic Fibrosis No drug interventions treatment 4 recruiting NCT03617718
Project 2 Airway Potential Hydrogen (pH) in Asthma No drug interventions diagnostic 1 / 2 recruiting NCT05026918
Manual Chest Physiotherapy and Active Cycle of Breathing Techniques (ACBT) in Patients of Cystic Fibrosis No drug interventions treatment Not Available completed NCT04226118
Efficacy of an Infrared Visualization Technique for the Identification of the Peripheral Venous Access Site in Patients With Cystic Fibrosis Aged 12 Years and Older No drug interventions health_services_research Not Available completed NCT01293019
Osteopathic Treatment in Adult Patients With Cystic Fibrosis No drug interventions treatment 3 completed NCT02976519
BI 443651 Multiple Rising Dose in Healthy Volunteers Followed by a Cross-over in CF Subjects No drug interventions treatment 1 completed NCT02742519
A Study to Evaluate Efficacy and Safety of Ivacaftor in Subjects With Cystic Fibrosis Aged 3 Through 5 Years Who Have a Specified CFTR Gating Mutation No drug interventions treatment 3 terminated NCT04608019
Streamlined Treatment of Pulmonary Exacerbations in Pediatrics No drug interventions treatment Not Available completed NCT02894619
Urinary and Anorectal Functional Disorders and Their Impact on CF Adults (PerineoMucoRMO) No drug interventions Not Available Not Available completed NCT03261219
IPV vs CPT for Airway Clearance During CF Exacerbation No drug interventions treatment Not Available withdrawn NCT02690519
Study of GLPG1837 in Subjects With Cystic Fibrosis (S1251N Mutation) No drug interventions treatment 2 completed NCT01636219
Cough Efficiency in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01784419
Short Term Effects of Ivacaftor in Non-G551D Cystic Fibrosis Patients No drug interventions screening Not Available completed NCT04596319
Ph 1/2 Study Evaluating Safety and Tolerability of Inhaled AP-PA02 in Subjects With Chronic Pseudomonas Aeruginosa Lung Infections and Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT05752019
TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era No drug interventions Not Available Not Available active_not_recruiting NCT01858519
Prevalence of Antibodies to Selected Porcine Viruses in Patients With Cystic Fibrosis Receiving Porcine-derived Pancreatic Enzyme Replacement Therapy No drug interventions Not Available Not Available completed NCT01337219
Pharmacokinetic Bioequivalence Study of Nebcinal® 150mg/3ml Administered by Aeroneb® Idehaler® Versus Tobi® 300mg/5ml Administered by Pari LC Plus® /Pulmoaid® in Patients With Cystic Fibrosis No drug interventions treatment 1 / 2 unknown_status NCT02399241
Using Remote Telemonitoring to Detect Early Decline in Lung Function & Streamline Clinics in Adults With Cystic Fibrosis No drug interventions health_services_research Not Available completed NCT00458341
A Study of Ataluren in Pediatric Participants With Cystic Fibrosis No drug interventions treatment 2 completed NCT04684641
CYstic Fibrosis bacterioPHage Study at Yale (CYPHY) No drug interventions treatment 1 / 2 completed NCT04094441
Modeling of Chest Physiotherapy Using Impedance Measurements (PHYSIOMOD) No drug interventions basic_science Not Available completed NCT05153317
Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older No drug interventions treatment 3 active_not_recruiting NCT00787917
An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA) No drug interventions treatment 4 terminated NCT05029817
Ovarian Reserve in Women With Cystic Fibrosis and the Correlation With Demographic and Clinical Parameters No drug interventions Not Available Not Available unknown_status NCT02994017
Prognostic Value of Functional Exercise Test (EFX) in Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT04353817
A Study Evaluating Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis and F/MF Genotypes No drug interventions treatment 3 completed NCT00843817
RhDNase and Biodistribution of PMN Serine Proteases in Cystic Fibrosis Sputum No drug interventions basic_science 4 completed NCT00265434
Nasal Inhalation of Dornase Alfa (Pulmozyme) in Patients With Cystic Fibrosis and Chronic Rhinosinusitis treatment 3 completed NCT01002534
Does a Nasal Instillation of Vardenafil Normalize the Nasal Potential Difference in Cystic Fibrosis Patients? No drug interventions treatment 2 terminated NCT03593434
Airway Clearance Therapy on Hyperpolarized 129Xenon and MRI No drug interventions Not Available Not Available completed NCT01180634
MP-376 (Aeroquin™, Levofloxacin for Inhalation) in Patients With Cystic Fibrosis No drug interventions treatment 3 completed NCT01201434
Effect of Probiotics on Sputum Inflammation and Pulmonary Infections in Patients With Cystic Fibrosis No drug interventions prevention Not Available terminated NCT00153634
Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF) treatment Not Available completed NCT04966234
A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection No drug interventions treatment 2 / 3 unknown_status NCT00889434
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) No drug interventions treatment Not Available completed NCT02392234
A Phase 3 Study to Evaluate the Efficacy and Safety of Ivacaftor and VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mutation No drug interventions treatment 3 completed NCT05568134
Alternate Measures of Glucose During OGTT Testing for CFRD No drug interventions Not Available Not Available recruiting NCT05576324
Effect of the CFTR-modulating Triple Therapy Elexacaftor - Tezacaftor - Ivacaftor No drug interventions Not Available Not Available recruiting NCT04187924
Effects of SIMEOX on Airway Clearance in Cystic Fibrosis No drug interventions treatment Not Available completed NCT04969224
A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF) No drug interventions treatment 3 completed NCT01343524
Changes in Lung Function Based on Differences in Spirometry Equipment Used in Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03540524
A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in Patients With Cystic Fibrosis. No drug interventions treatment 1 completed NCT03961516
Glycemic Characterization and Pancreatic Imaging Correlates in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02950116
Lung Clearance Index (LCI) in Pediatric Patients With Obstructive Lung Disease No drug interventions diagnostic Not Available terminated NCT01956916
Probiotics in Cystic Fibrosis No drug interventions prevention 3 completed NCT00680316
A Study of Pulmozyme® (Dornase Alpha) in 3- to 5-Year-Old Patients With Cystic Fibrosis No drug interventions treatment 4 terminated NCT02883816
Early Assessment of Respiratory Function, Inflammation and Bronchial Reshuffle Among Newborns Screened for Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT05195216
Psychosocial Factors and Quality of Life in the Effect of Fear of COVID-19 With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT04620096
MENstrual Symptom Tracking to Understand and Assess (Women) Living With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00163696
Multi Breath Nitrogen Washout (MBNW) as a Measure of Small Airway Function in Patients With Respiratory Disease No drug interventions Not Available Not Available unknown_status NCT03607396
Study for Evaluating the Real Use of Inhaled Aztreonam Lysine in Patients With Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT03736096
Molecular Diagnosis of Respiratory Viral Infections on Sputum From Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT00004296
Multicenter Study of Nontuberculous Mycobacteria in Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT04166396
Non-pulmonary Contributors of Exercise Intolerance in Patients With Cystic Fibrosis No drug interventions treatment 0 recruiting NCT03277196
A Study to Evaluate the Safety of Long-term Ivacaftor Treatment in Subjects With Cystic Fibrosis Who Are Less Than 24 Months of Age at Treatment Initiation and Have an Approved Ivacaftor-Responsive Mutation No drug interventions treatment 3 completed NCT01355796
Inhaled Xylitol Versus Saline in Stable Subjects With Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT03672058
Steps Ahead: Optimising Physical Activity and Health in Adults With Cystic Fibrosis No drug interventions treatment Not Available unknown_status NCT01025258
Improving Adherence and Clinical Outcome in Cystic Fibrosis (CF) Patients No drug interventions treatment Not Available completed NCT02188758
Biomarkers of Iron Homeostasis and Responses to Cystic Fibrosis Pulmonary Exacerbation (CFPE) Treatment No drug interventions Not Available Not Available completed NCT06057558
Airway Microbiome of Cystic Fibrosis Patients No drug interventions supportive_care Not Available active_not_recruiting NCT05599958
Clinical and Genetic Profile of Pediatric Patients With Cystic Fibrosis in Sohag. No drug interventions Not Available Not Available completed NCT02141958
Safety Study of Fenretinide in Adult Patients With Cystic Fibrosis No drug interventions treatment 1 completed NCT02239458
DPP-IV Inhibition Prior to Development of Diabetes in Patients With Cystic Fibrosis No drug interventions supportive_care Not Available unknown_status NCT00308958
Comparison of Airway Clearance Efficacy of Two High Frequency Chest Wall Oscillation (HFCWO) Devices in Cystic Fibrosis No drug interventions treatment Not Available completed NCT00743158
Transfer Impedance in Cystic Fibrosis No drug interventions Not Available Not Available withdrawn NCT00977158
Microbiota of the Respiratory Flora in Children With Cystic Fibrosis During the First Year of Life No drug interventions Not Available Not Available withdrawn NCT06133335
Cystic Fibrosis and Periodontal Diseases No drug interventions other Not Available recruiting NCT00685035
Comparison of Airway Clearance Therapy in Cystic Fibrosis Using the Same VEST Therapy Device But With Different Settings No drug interventions treatment 4 completed NCT06237335
A Phase 1 Study Evaluating Safety and Tolerability of RCT2100 in Healthy Participants and in Participants with CF No drug interventions treatment 1 recruiting NCT00928135
Aerosolized Hypertonic Xylitol Versus Hypertonic Saline in Cystic Fibrosis (CF) Subjects No drug interventions other 1 / 2 completed NCT06560463
Continuous Glucose Monitoring and OGTT Screen for Cystic Fibrosis Related Diabetes in Cystic Fibrosis No drug interventions Not Available Not Available not_yet_recruiting NCT03795363
Orkambi Treatment in 2 to 5 Year Old Children With CF No drug interventions Not Available Not Available completed NCT04613063
Proximal Intestinal Obstruction Syndrome (PIOS) in a Patient With Cystic Fibrosis: A New Syndrome No drug interventions Not Available Not Available completed NCT02048163
Intermittent Versus Continuous Infusion Meropenem in Cystic Fibrosis No drug interventions Not Available Not Available withdrawn NCT02015663
Tobramycin Inhalation Powder (TIP) Administered Once Daily Continuously Versus TIP Administered BID in 28 Day on / 28 Day Off Cycles No drug interventions treatment 4 terminated NCT00546663
Tolerability of Inhaled Hypertonic Saline in Infants With Cystic Fibrosis No drug interventions treatment Not Available completed NCT06184763
Evolution of the 6-minute Walk Test in Patients Treated With ELEXACAFTOR / TEZACAFTOR / IVACAFTOR No drug interventions Not Available Not Available active_not_recruiting NCT05865886
A Study to Test How Well BI 1291583 is Tolerated by People With Cystic Fibrosis Bronchiectasis (Clairafly™) No drug interventions treatment 2 active_not_recruiting NCT03424486
Prevalence and Impact of Depression and Anxiety in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02039986
Ivacaftor (Kalydeco) and Insulin in Cystic Fibrosis (CF) No drug interventions Not Available Not Available completed NCT03377686
Breath Analysis in Children by New Point-of-care Instruments No drug interventions Not Available Not Available completed NCT02802839
Virtual Reality for the Reduction of Pain During Venipuncture in Children With CF No drug interventions Not Available Not Available unknown_status NCT04469439
Impact of Sinus Surgery on Individuals With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT01086839
Sino-nasal Inhalation of Sodium Chloride 6,0% in Patients With Cystic Fibrosis and Chronic Rhinosinusitis No drug interventions treatment Not Available completed NCT00362739
Blood Collection From Individuals With Lung Disease for Genetic Studies No drug interventions Not Available Not Available completed NCT02971839
Study to Evaluate the Safety and Efficacy of CTP-656 in Patients With Cystic Fibrosis With CFTR Gating Mutations No drug interventions treatment 2 terminated NCT03435939
Effect of Losartan in Cystic Fibrosis (CF)-NIH Grant #133240 No drug interventions other 0 recruiting NCT00951522
A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of GS-9411 in Healthy Male Volunteers No drug interventions treatment 1 completed NCT04391322
Assessment of CFTR-Modulator Treatment in Cystic Fibrosis Lung Disease Using Novel Structural and Functional MRI No drug interventions Not Available Not Available recruiting NCT02722122
Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Exploratory Efficacy Parameters of AIR DNase™in Patients With Cystic Fibrosis Previously Treated With Pulmozyme® No drug interventions treatment 2 unknown_status NCT02684422
Initial and Chronic Methicillin Resistant Staphylococcus Aureus (MRSA) Infection in Cystic Fibrosis (CF) No drug interventions Not Available Not Available completed NCT03756922
A DDI Study of FDL169 and FDL176 in Healthy Subjects No drug interventions treatment 1 / 2 suspended NCT01181622
A Safety and Tolerability Study of Denufosol in 2-4 Year Olds No drug interventions treatment 2 completed NCT05422222
Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age No drug interventions treatment 3 recruiting NCT05249322
Study of Satisfaction of Patients and Care Providers for an Alternate Follow-up With In-hospital Consults and Tele-consult for Patients With Cystic Fibrosis No drug interventions health_services_research Not Available recruiting NCT00298922
Azithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex No drug interventions treatment 2 unknown_status NCT01937325
CPET in CF Patients With One G551D Mutation Taking VX770 No drug interventions basic_science 4 unknown_status NCT00043225
The Role of Bacteria and Genetic Variations in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT06122025
Evaluation of Patient Access to People With Cystic Fibrosis (CF) and Healthcare Professionals No drug interventions other Not Available completed NCT06159725
A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis No drug interventions treatment 1 / 2 recruiting NCT04970225
Cystic Fibrosis Blood Neutrophils No drug interventions basic_science Not Available recruiting NCT02535130
Evaluation of Nebulization and Positive Expiratory Pressure Combination No drug interventions treatment Not Available unknown_status NCT00455130
A Phase 2 Study to Determine the Safety and Efficacy of Inhaled Dry Powder Mannitol in Cystic Fibrosis No drug interventions treatment 2 completed NCT00590330
Microbial Community Composition and Dynamics in Lungs of Cystic Fibrosis Sibling Pairs No drug interventions Not Available Not Available completed NCT00287430
Growth Hormone Use in Adolescents and Adults With Cystic Fibrosis treatment Not Available withdrawn NCT00982930
Open Label Extension to Bridging Study CTBM100C2303 No drug interventions treatment 3 completed NCT05599230
Daily Monitoring of Respiratory Symptoms and Spirometry During ETI Treatment in Persons With Cystic Fibrosis. No drug interventions Not Available Not Available active_not_recruiting NCT02821130
Orkambi Exercise Study No drug interventions Not Available Not Available completed NCT04760548
Segmentation of Structural Abnormalities in Chronic Lung Diseases No drug interventions Not Available Not Available active_not_recruiting NCT06132048
A Usability Validation of the MuCopilot Mobile Application, a Digital Tool for the Unsupervised Objective Assessment of Cystic Fibrosis No drug interventions other Not Available not_yet_recruiting NCT05482048
Pilot Trial of ExACT (Exercise as Airway Clearance Therapy) for People With Cystic Fibrosis No drug interventions treatment Not Available active_not_recruiting NCT03000348
A Study of the Dosing, Efficacy, and Safety of Oral Cysteamine in Adult Patients With Cystic Fibrosis Exacerbations No drug interventions treatment 2 completed NCT04058548
Clinical Utility of the 1-minute Sit to Stand Test as a Measure of Submaximal Exercise Tolerance in Patients With Cystic Fibrosis During Acute Pulmonary Exacerbation No drug interventions health_services_research Not Available completed NCT05745948
COVID-19 ANtibody Responses in Cystic Fibrosis: CAR-CF No drug interventions Not Available Not Available recruiting NCT02831348
Association of Transcutaneous Pulse CO-oximetry With Inflammatory Lung Diseases No drug interventions Not Available Not Available completed NCT05882357
Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age No drug interventions treatment 3 recruiting NCT02347657
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor No drug interventions treatment 3 completed NCT03947957
Microbial Biomarkers of EArly Pseudomonas Aeruginosa Colonization in CHildren With Cystic Fibrosis No drug interventions diagnostic Not Available active_not_recruiting NCT00918957
A Study of Tobramycin Inhalation Powder From a Modified Manufacturing Process Versus Placebo No drug interventions treatment 3 completed NCT04467957
Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis No drug interventions diagnostic 4 active_not_recruiting NCT02722057
A Study to Confirm the Long-term Safety and Effectiveness of Kalydeco in Patients With Cystic Fibrosis Who Have an R117H-CFTR Mutation, Including Pediatric Patients No drug interventions Not Available Not Available completed NCT01626157
A Novel Assay to Quantify Treatment Response in Cystic Fibrosis (CF) No drug interventions Not Available Not Available completed NCT00333957
Capsule Endoscopy in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02932657
Perceived Impact of Art Therapy in Patients With Cystic Fibrosis and in Professional Interdisciplinary Teams Taking Care of Them. No drug interventions Not Available Not Available completed NCT05444257
A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy No drug interventions treatment 3 active_not_recruiting NCT03560726
Telehealth Cognitive Behavioral Stress Management for Adults With Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT04938726
Ketone Supplementation in Cystic Fibrosis No drug interventions treatment Not Available completed NCT02947126
Multilevel Models of Therapeutic Response in the Lungs No drug interventions basic_science 1 completed NCT03633526
Evaluation of VX-659/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age No drug interventions treatment 3 terminated NCT02965326
Surrogate Markers of Response to New Therapies in Cystic Fibrosis Patients No drug interventions basic_science Not Available recruiting NCT04249466
Diet, Physical Activity and Glucose Tolerance in Cystic Fibrosis. Exploratory Study. No drug interventions Not Available Not Available completed NCT01815866
Cough-Generated Aerosols of NTM in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT06273566
French Validation of the AdT-Physio Scale No drug interventions Not Available Not Available recruiting NCT00388466
Whole Body Vibration - a New Therapeutic Approach to Improve Muscle Function in CF No drug interventions treatment Not Available completed NCT03625466
A Study to Explore the Impact of Lumacaftor/Ivacaftor on Disease Progression in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del No drug interventions treatment 2 completed NCT01479166
Bronchial Inflammation of Small Airways in Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT04058366
Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy No drug interventions treatment 3 completed NCT03421366
Modified Release Posaconazole in Patients With Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT00687466
Study on the Efficacy of Slow Release Insulin in Cystic Fibrosis Patients With Glucide Intolerance and Clinical Decay No drug interventions treatment 3 unknown_status NCT02295566
RATNO, Reducing Antibiotic Tolerance Using Nitric Oxide in CF - a Phase 2 Pilot Study No drug interventions treatment 2 completed NCT01605565
Functional Analysis by Dynamic Imaging of the Respiratory Epithelium in Infants With Cystic Fibrosis No drug interventions basic_science Not Available unknown_status NCT00425165
Study of Denufosol Inhalation Solution in Patients With Mild to Moderate Cystic Fibrosis Lung Disease No drug interventions treatment 2 terminated NCT06072365
Treatment With Elexacaftor/Tezacaftor/Ivacaftor, in Patients With Cystic Fibrosis and Caloric Intake No drug interventions Not Available Not Available completed NCT00023465
Quantification of Pulmonary Neutrophil Activity in Cystic Fibrosis Using Radiolabeled Fluorodeoxyglucose and PET Imaging No drug interventions Not Available Not Available unknown_status NCT06350474
Impact of Discontinuing Dornase Alfa in People With CF on Highly Effective CFTR Modulator Therapy-A SIMPLIFY Sub-Study No drug interventions other Not Available completed NCT05687474
Baby Detect : Genomic Newborn Screening No drug interventions Not Available Not Available recruiting NCT02753374
Registry Study on Cystic Fibrosis in Chinese Children No drug interventions Not Available Not Available not_yet_recruiting NCT05766774
FEED-Cystic Fibrosis (FEED-CF) No drug interventions prevention Not Available recruiting NCT00266474
Prevalence of Chronic Rhinosinusitis in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT05437120
Pharmacokinetics and Safety Assessment of VX-121/Tezacaftor/Deutivacaftor in Participants With Moderate Hepatic Impairment No drug interventions basic_science 1 completed NCT00499720
Aztreonam Lysine for Inhalation in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Airway Infection No drug interventions Not Available Not Available approved_for_marketing NCT02421120
Population Pharmacokinetics and Safety of Intravenous Ceftolozane/Tazobactam in Adult Cystic Fibrosis Patients No drug interventions other 4 completed NCT00104520
Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Cystic Fibrosis Patients With P. Aeruginosa No drug interventions treatment 3 completed NCT04395820
Prospective Surveillance of Lung Development During Childhood, Adolescence and Adulthood in Healthy and Patients With Cystic Fibrosis No drug interventions Not Available Not Available active_not_recruiting NCT04242420
Connexin Genotypes in Cystic Fibrosis No drug interventions diagnostic Not Available recruiting NCT04685720
A Pilot Study to Assess the Effect of Intermittent iNO on the Treatment of NTM Lung Infection in CF and Non-CF Patients No drug interventions treatment Not Available completed NCT03320382
Multiple Breath Washout, a Clinimetric Dataset No drug interventions Not Available Not Available unknown_status NCT06262282
Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria No drug interventions Not Available Not Available enrolling_by_invitation NCT06175182
Assessment of Cognitive Function and Exercise Capacity in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT02626182
Evaluation and Treatment of Pulmonary Vascular Disease in Moderate to Severe CF No drug interventions treatment 1 / 2 completed NCT02201082
Evaluation of the Timing of the Nebulization Related to the Physiotherapy Session No drug interventions treatment Not Available completed NCT00485082
Disclosing a Cystic Fibrosis Diagnosis to a Dating Partner No drug interventions Not Available Not Available completed NCT00916682
Structure and Function of Salivary Proteins No drug interventions Not Available Not Available unknown_status NCT05584982
Clinical Performance of the AtbFinder® Test System for Selection of Antibiotic Therapy in Persons With Cystic Fibrosis No drug interventions diagnostic Not Available completed NCT04847882
Case-control Study of Sleep Disorders in Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01285882
Representations of Transplantation in Patients and in Health Care Professionals No drug interventions Not Available Not Available completed NCT02951182
A Study Evaluating the Safety and Efficacy of VX-440 Combination Therapy in Subjects With Cystic Fibrosis No drug interventions treatment 2 completed NCT00531882
Pilot Mouthwash Study of Pioglitazone and Simvastatin in Healthy Volunteers No drug interventions other Not Available completed NCT00416182
Nasally Delivered Pulmozyme for Sinusitis in Cystic Fibrosis No drug interventions treatment 2 completed NCT03859531
Gastrointestinal Study at Orkambi Therapy in CF Patients No drug interventions Not Available Not Available unknown_status NCT00531531
Evaluation of the Emission Distance of P. Aeruginosa From the Respiratory Tract of People With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03061331
Lumacaftor/Ivacaftor Combination Therapy in Subjects With CF Who Have an A455E CFTR Mutation No drug interventions treatment 2 completed NCT00999531
A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Trial of GS-9411 in Healthy Volunteers No drug interventions treatment 1 completed NCT04126473
A Phase 2 Study to Evaluate the Safety, Tolerability, PK and PD in Cystic Fibrosis Patients With at Least 1 G542X Allele No drug interventions treatment 2 completed NCT04863573
COVID-19 Antibody Responses In Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT01266473
Study of Individualized Physiotherapy for Airway Clearance in Cystic Fibrosis. No drug interventions treatment Not Available completed NCT04006873
Gut Imaging for Function & Transit in Cystic Fibrosis Study 2 No drug interventions other 2 completed NCT03645473
Evaluation of Device Settings for Airway Clearance Using The Monarch Airway Clearance System No drug interventions device_feasibility Not Available unknown_status NCT01222273
Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis No drug interventions treatment Not Available completed NCT00006273
Study of Total Energy Expenditure in Infants and Children With Moderate to Severe Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT06032273
Lung Transplant READY CF 2: CARING CF Ancillary RCT No drug interventions other Not Available recruiting NCT00846573
Hyperpolarized Noble Gas MR Imaging for Pulmonary Disorders No drug interventions diagnostic Not Available terminated NCT05795673
Peer-supporting for Teenagers With Cystic Fibrosis in the Transition of Care From Paediatric to Adult Services No drug interventions other Not Available not_yet_recruiting NCT03173573
A Study to Assess the Safety, Tolerability and PK Profile of FDL176 in Healthy and CF Participants No drug interventions treatment 1 completed NCT06468527
Clinical Trial to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/Nesolicaftor in Adults With CF No drug interventions treatment 2 recruiting NCT06313827
e-Health Program to Prevent Exacerbations in the Cystic Fibrosis Population No drug interventions prevention Not Available not_yet_recruiting NCT01889927
INSPIRE-CF: an Alternative Physiotherapy Model for Children With Cystic Fibrosis No drug interventions treatment Not Available completed NCT06364176
Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis. No drug interventions treatment 2 recruiting NCT03423576
Effects of a Comprehensive Patient-centered Health Service in Cystic Fibrosis (VEMSE-CF) No drug interventions health_services_research Not Available completed NCT06429176
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis No drug interventions treatment 2 recruiting NCT01316276
Extension Study of Liposomal Amikacin for Inhalation in Cystic Fibrosis (CF) Patients With Chronic Pseudomonas Aeruginosa (Pa) Infection No drug interventions treatment 3 completed NCT00391976
Efficacy and Safety of 28 or 56 Day Treatment for Pseudomonas Aeruginosa in Children With Cystic Fibrosis No drug interventions treatment 3 completed NCT03921060
Markers of Osteoporosis in Cystic Fibrosis No drug interventions diagnostic 4 recruiting NCT02277860
Gaming Console Home-Based Exercise for Adults With Cystic Fibrosis No drug interventions treatment Not Available completed NCT00677560
The Natural History of Small Airways Physiology in Diseased and Healthy States No drug interventions Not Available Not Available completed NCT04702360
ELX/TEZ/IVA Expanded Access Program for Cystic Fibrosis (CF) Patients With at Least One F508del Mutation No drug interventions Not Available Not Available approved_for_marketing NCT03482960
Comparison of 129Xe MRI With 19F MRI in CF Lung Disease No drug interventions other 0 completed NCT02848560
Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRI No drug interventions Not Available Not Available active_not_recruiting NCT00809094
NAC Phase IIB: A Multi-Center, Phase IIB, Randomized, Placebo-controlled, Double-Blind Study Of The Effects Of N-Acetylcysteine On Redox Changes and Lung Inflammation In Cystic Fibrosis Patients No drug interventions treatment 2 completed NCT03494894
Bacteriological Link Between Upper and Lower Airways in Cystic Fibrosis and Primary Ciliary Dyskinesia No drug interventions Not Available Not Available completed NCT03367494
A New Optical Sweat Test Method Based on a Citric Acid-derived Multi-halide Sensor No drug interventions diagnostic Not Available terminated NCT05726994
Volatilomic Approaches for the Study of CFTR Modulators (VOLATIL-CF) No drug interventions Not Available Not Available recruiting NCT00863694
Fecal Calprotectin in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT04059094
A 4-week Study to Test Different Doses of BI 1265162 in Adolescents and Adults With Cystic Fibrosis Using the Respimat® Inhaler - BALANCE - CF™1 No drug interventions treatment 2 terminated NCT01572194
Predictive Value of PIIINP Urinary for the Development of Chronic Renal Failure in Patients With Cystic Fibrosis After Lung Transplantation (MUCO-IRC) No drug interventions diagnostic Not Available terminated NCT01667094
A Study Comparing Continuous Infusion Antibiotics to Standard Treatment for Lung Infections in Cystic Fibrosis No drug interventions treatment 4 unknown_status NCT05052294
COVID-19 Antibody Responses in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT03551691
Proton Pump Inhibitors (PPI) and Fat Absorption in Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI) No drug interventions treatment 2 completed NCT01661491
Microbiome Acquisition and Progression of Inflammation and Airway Disease in Infants and Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03809091
WGS of Korean Idiopathic Bronchiectasis No drug interventions Not Available Not Available unknown_status NCT01543191
A Safety and Tolerability Study OF PUR118 In Subjects With Cystic Fibrosis No drug interventions treatment 1 completed NCT05359991
Exercise in Child Health No drug interventions basic_science Not Available recruiting NCT00633191
Anti-pseudomonas IgY to Prevent Infections in Cystic Fibrosis No drug interventions prevention 1 / 2 completed NCT03559062
A Study to Evaluate Efficacy and Safety of TEZ/IVA in Subjects Aged 6 Through 11 Years With Cystic Fibrosis No drug interventions treatment 3 completed NCT04302662
Phase 2 Combination Study With Escalating Doses of MS1819-SD on Top of a Stable Dose of PPEs No drug interventions treatment 2 completed NCT00934362
Effect of Lucinactant on Mucus Clearance in Cystic Fibrosis Lung Disease No drug interventions treatment 2 completed NCT02707562
Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation) No drug interventions treatment 2 completed NCT03357562
MR Imaging of Lung in the Follow-up Assessment of Cystic Fibrosis No drug interventions prevention Not Available active_not_recruiting NCT05074680
COVID-19 Antibody Responses In Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT02368080
Multiple Breath Nitrogen Washout in Healthy and Cystic Fibrosis Adults No drug interventions Not Available Not Available completed NCT00446680
Long Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis - A Safety and Efficacy Study No drug interventions treatment 3 completed NCT00237380
Safety and Efficacy of Ataluren (PTC124) for Cystic Fibrosis treatment 2 completed NCT01569880
Pre-flight Evaluation of Adult Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT05654480
Combating Diagnostic Wandering and Impasse for Cystic Fibrosis No drug interventions Not Available Not Available not_yet_recruiting NCT00006280
A Study of the Safety and Efficacy of Tobramycin for Inhalation in Young Children With Cystic Fibrosis treatment 2 completed NCT00817180
Long-term Study, Comparing Vest Therapy to Positive Expiratory Pressure (PEP) Therapy in the Treatment of Cystic Fibrosis No drug interventions treatment 2 completed NCT02496780
The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients No drug interventions treatment 2 / 3 completed NCT01331980
Bone Microarchitecture at the Radius: a Pilot Comparison Between Children With Cystic Fibrosis and Healthy Controls No drug interventions Not Available Not Available completed NCT05033080
A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF) No drug interventions treatment 3 completed NCT00709280
Infant Study of Inhaled Saline in Cystic Fibrosis No drug interventions treatment Not Available completed NCT05200429
Canadian Observational Study Evaluating the Long-term IMPACT of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators on People With CF No drug interventions Not Available Not Available recruiting NCT00659529
Safety and Efficacy of Sildenafil in Cystic Fibrosis (CF) Lung Disease No drug interventions treatment 1 / 2 completed NCT03853629
Air Pollution and Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT05998629
Skin-interfaced Colorimetric Bifluidic Sweat Sensor Device for the Diagnosis of Cystic Fibrosis (CF) No drug interventions diagnostic Not Available recruiting NCT03489629
STaph Aureus Resistance-Treat Early and Repeat (STAR-TER) No drug interventions treatment 2 recruiting NCT02025829
IL-17 Neutrophils in CF Lung Inflammation No drug interventions Not Available Not Available completed NCT05158829
COVID-19 Antibody Responses In Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT04458129
Polyethylene Glycol and Intestinal Inflammation in Cystic Fibrosis No drug interventions treatment 2 unknown_status NCT02309229
Sputum Purulence as a Predictor of Cystic Fibrosis Exacerbations: a Prospective Cohort Trial. No drug interventions Not Available Not Available completed NCT04543929
Effects of Innovative Aerobic Exercise Training in Cystic Fibrosis No drug interventions treatment Not Available unknown_status NCT01465529
A Cross-over Study of OligoG in Subjects With Cystic Fibrosis. Fibrosis No drug interventions treatment 1 / 2 completed NCT02569229
Glucose Tolerance in Children With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03768089
Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT02122289
Muco Smartphone Exacerbation No drug interventions supportive_care 0 completed NCT02419989
PATIENCE Trial: Prospective Algorithm for Treatment of NTM in Cystic Fibrosis No drug interventions Not Available Not Available enrolling_by_invitation NCT03056989
A Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis No drug interventions treatment 1 completed NCT02310789
(Study: Vertex IIS) Does Ivacaftor Alter Wild Type CFTR-Open Probability In The Sweat Gland Secretory Coil? No drug interventions basic_science Not Available completed NCT04217889
Cystic Fibrosis Adherence Study No drug interventions Not Available Not Available completed NCT06504589
A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators No drug interventions Not Available Not Available not_yet_recruiting NCT02453789
A Study of OligoG in Cystic Fibrosis Subjects With Burkholderia Spp. Infection No drug interventions treatment 2 completed NCT01381289
VX-770 Expanded Access Program No drug interventions Not Available Not Available approved_for_marketing NCT00004489
Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis treatment Not Available completed NCT05675592
Trikafta/Kaftrio and Pseudomonas Aeruginosa No drug interventions Not Available Not Available recruiting NCT00742092
Miglustat in Cystic Fibrosis No drug interventions treatment 2 completed NCT00128492
Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Cystic Fibrosis (CF) Patients With Pseudomonas Aeruginosa (PA) No drug interventions treatment 3 completed NCT03565692
Lum-Iva-biota: Exploring the Respiratory Mycobiota and Microbiota Profile in French CF Patients Taking Lumacaftor-Ivacaftor No drug interventions Not Available Not Available unknown_status NCT01377792
Study of Long-term Treatment With Hypertonic Saline in Patients With Cystic Fibrosis No drug interventions treatment 4 completed NCT05809492
Use of A-STEP Test in Cystic Fibrosis Patients No drug interventions supportive_care Not Available recruiting NCT01100892
Cystic Fibrosis - Insulin Deficiency, Early Action No drug interventions treatment 3 completed NCT00506792
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QAU145 in Patients With Cystic Fibrosis No drug interventions treatment 2 completed NCT03622892
Non-invasive Prenatal Diagnosis of Monogenic Disorders by Linked-reads Technology No drug interventions Not Available Not Available unknown_status NCT01931644
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions No drug interventions Not Available Not Available completed NCT05362344
Colorectal Cancer Screening in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT04392544
Intestinal Inflammation in CF Patients No drug interventions Not Available Not Available active_not_recruiting NCT05748444
The Relationship Between Diet and Glycemic Response and Inflammatory Markers in Children With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT03734744
PK/PD of Vitamin D3 in Adults With CF No drug interventions treatment Not Available terminated NCT00016744
Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous(for Cystic Fibrosis) basic_science 1 / 2 completed NCT00558844
Safety/Tolerability Study of Arikayce™ in Cystic Fibrosis Patients With Chronic Infection Due to Pseudomonas Aeruginosa No drug interventions treatment 1 / 2 completed NCT01710644
Efficacy and Tolerability of NM-BL in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis No drug interventions treatment 1 / 2 completed NCT04777344
Clinical Effort Against Smoke Exposure in Cystic Fibrosis No drug interventions health_services_research Not Available completed NCT02589444
Vitamin D and Microbiota in Cystic Fibrosis No drug interventions supportive_care Not Available completed NCT03290144
Pregnancies and Cystic Fibrosis No drug interventions Not Available Not Available unknown_status NCT04235140
Long-term Safety of Lumacaftor/Ivacaftor in Subjects With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation No drug interventions treatment 3 completed NCT02178540
Study to Validate the Instructions for Use of TOBI® Podhaler™ in Cystic Fibrosis Patients No drug interventions Not Available 4 completed NCT02199340
The iStep Study: Development and Validation of an Incremental Exercise Step Test for Children With Cystic Fibrosis No drug interventions basic_science Not Available completed NCT05279040
Trikafta Exercise Study in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT02417740
Natural History of Noncirrhotic Portal Hypertension No drug interventions Not Available Not Available recruiting NCT01379040
Volatile Organic Compounds in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00413140
Non-Invasive Biomarkers in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT05140967
Effects of Training Intensity on Physical Fitness and Body Composition in Cystic Fibrosis No drug interventions treatment Not Available active_not_recruiting NCT01450267
Inhaled Glutathione (GSH) Versus Placebo in Cystic Fibrosis No drug interventions treatment 3 unknown_status NCT05251467
A Comprehensive Approach To Relief Of Digestive Symptoms In Cystic Fibrosis: CARDS-CF No drug interventions Not Available Not Available completed NCT01953367
Bioequivalence and Safety of Vantobra and TOBI in Healthy Subjects No drug interventions basic_science 1 completed NCT02725567
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Ivacaftor in Subjects With Cystic Fibrosis Who Are Less Than 24 Months of Age and Have an Ivacaftor-Responsive CFTR Mutation No drug interventions treatment 3 completed NCT04882267
General Health, Attitudes, and Activity in Self-directed Exercise in Patients With Cystic Fibrosis (GAINS-CF) No drug interventions supportive_care Not Available unknown_status NCT00297167
Study to Evaluate the Safety and Efficacy of EUR-1008 (APT-1008) Pancreatic Enzyme Product in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency No drug interventions treatment 3 completed NCT04888767
Safety and Feasibility of High-intensity Interval Training Program in CF Patients No drug interventions treatment Not Available completed NCT04793867
Regional Phenotyping of CF and Non-CF Bronchiectasis No drug interventions Not Available Not Available recruiting NCT03492567
Study of Circulating Blood Cell Monocytes as Predictive Biomarker of Bone Cystic Fibrosis Disease. Impact of CFTR Correctors. No drug interventions basic_science Not Available completed NCT04402801
Patient Outcomes of Clinic Transition From Face to Face Encounter to Telemedicine in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01737801
Time to Perform Lung Function Test in Cystic Fibrosis No drug interventions treatment Not Available completed NCT00060801
Efficacy and Safety of 24 Weeks of Oral Treatment With BIIL 284 BS in Adult and Pediatric Patients No drug interventions treatment 2 terminated NCT03295201
Clinical Effects of Exercise Program Added to Pulmonary Rehabilitation in Patients With Cystic Fibrosis No drug interventions treatment Not Available completed NCT00903201
28 Day Repeat Dose in Cystic Fibrosis Patients No drug interventions treatment 2 completed NCT02252601
Evaluation of the High Frequency Digit Triplet Test in Cystic Fibrosis No drug interventions screening Not Available unknown_status NCT00457301
Using Health-related Quality of Life (HRQL) in Routine Clinical Care No drug interventions Not Available Not Available completed NCT03624101
Novel Therapeutic Approaches for Treatment of CF Patients With W1282X Premature Termination Codon Mutations No drug interventions treatment 4 recruiting NCT00072904
Diabetes Therapy to Improve BMI and Lung Function in CF treatment 3 completed NCT05090904
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Fibrosis No drug interventions treatment 2 completed NCT00706004
Short Term Safety and Efficacy of Lubiprostone in Adults With Cystic Fibrosis No drug interventions treatment Not Available completed NCT01094704
Durability of Hypertonic Saline for Enhancing Mucociliary Clearance in Cystic Fibrosis No drug interventions basic_science 1 completed NCT02190604
Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients No drug interventions treatment 1 / 2 terminated NCT00865904
Study of VX-809 in Cystic Fibrosis Subjects With the ∆F508-CFTR Gene Mutation No drug interventions treatment 2 completed NCT03892304
Gynecological Health Improvement of Adult Women With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02524704
Electrical Impedance Imaging of Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT05700604
Hypoglycemia and Glucagon Response in CF No drug interventions Not Available Not Available completed NCT03205904
Nutritional Intervention and Glycemic Improvement in Patients With Pre-diabetic Cystic Fibrosis. No drug interventions prevention Not Available completed NCT06216704
Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT00221572
Can Quantitative Ultrasound be Used for the Evaluation of Bone Health in Adolescents and Adults With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT04731272
GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance No drug interventions other 2 recruiting NCT00774072
Nasal Inhalation of Tobramycin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization No drug interventions treatment 2 completed NCT01860872
Comparing Chest Images From MRI to CT in Patients With Cystic Fibrosis (CF) No drug interventions Not Available Not Available completed NCT00202072
Mucin in Sputum of CF During Pulmonary Exacerbation No drug interventions Not Available Not Available unknown_status NCT03670472
Correction of Nonsense Mutations in Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT01957072
Pilot Study of Behavioural Intervention for Nutrition in Cystic Fibrosis No drug interventions health_services_research Not Available completed NCT01686672
Web-based Delivery of Effective Treatment for Growth in Cystic Fibrosis No drug interventions treatment Not Available completed NCT00014768
Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis Not Available Not Available terminated NCT06084468
Cardiac Structure and Function in Patients With Cystic Fibrosis No drug interventions Not Available Not Available active_not_recruiting NCT03058068
Human MesenchymAl Stem Cells Infusion in Patients With Cystic Fibrosis No drug interventions treatment 1 withdrawn NCT00906568
Evaluation of Bronchial Inflammation in Allergic Bronchopulmonary Aspergillosis (ABPA) No drug interventions Not Available Not Available completed NCT02324868
Impact of Availability of Showerpatch for Patients With Intravenous Catheters No drug interventions supportive_care Not Available terminated NCT00322868
Safety and Efficacy of Pioglitazone as an Anti-inflammatory for the Treatment of Cystic Fibrosis (CF) Lung Disease No drug interventions treatment Not Available completed NCT01303068
Detection of Pseudomonas Aeruginosa in the Airways of Patients With CF No drug interventions diagnostic Not Available completed NCT04602468
Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER) No drug interventions other 4 active_not_recruiting NCT01018368
Study of VX-770 and Rifampin in Healthy Male Subjects No drug interventions treatment 1 completed NCT04580368
Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 Trials No drug interventions treatment Not Available recruiting NCT03256968
PTC Study to Evaluate Ataluren in Combination With Ivacaftor No drug interventions treatment 4 completed NCT00006169
Behavioral Treatment of Weight Gain in CF No drug interventions prevention 3 completed NCT01880346
Comparison of Absorption of Vitamin D in Cystic Fibrosis No drug interventions prevention 4 completed NCT05095246
A Study of Inhaled KB407 for the Treatment of Cystic Fibrosis No drug interventions treatment 1 withdrawn NCT00125346
Tobramycin Inhalation Powder (TIP) in Cystic Fibrosis Subjects treatment 3 terminated NCT00970346
Safety and Efficacy of Inhaled OligoG CF-5/20 for the Treatment Cystic Fibrosis No drug interventions treatment 1 completed NCT04133246
Parenting Concerns in Patients With Cystic Fibrosis (MucoPar) No drug interventions supportive_care Not Available completed NCT00625612
Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis (CF) Lung Disease No drug interventions treatment 3 completed NCT03068312
A Study to Evaluate Efficacy of Ivacaftor in Subjects With Cystic Fibrosis Who Have a 3849 + 10KB C→T or D1152H CFTR Mutation No drug interventions treatment 3 completed NCT00630812
Long Term Administration of Inhaled Mannitol in Cystic Fibrosis No drug interventions treatment 3 completed NCT01427712
Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis No drug interventions Not Available Not Available completed NCT05285410
Observational Study Comparing Home to Office Spirometry No drug interventions Not Available Not Available completed NCT02516410
A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation No drug interventions treatment 3 completed NCT04038710
Clinical Outcomes of Triple Combination Therapy in Severe Cystic Fibrosis Disease. No drug interventions Not Available Not Available completed NCT00959010
Omega 3 Supplementation in Cystic Fibrosis Patients No drug interventions treatment 3 completed NCT00719381
Effect of Pioglitazone on Inflammation in Cystic Fibrosis No drug interventions treatment 1 completed NCT00476281
Nutritional, Metabolic and Respiratory Status in Cystic Fibrosis No drug interventions basic_science Not Available completed NCT03475381
Real-life Follow-up of Cystic Fibrosis Patients Treated With Ivacaftor+Lumacaftor (Orkambi*) No drug interventions Not Available Not Available completed NCT04879381
Epidemiology of Anaerobic Bacteria in Cystic Fibrosis Patients: Descriptive and Non-interventional Study No drug interventions Not Available Not Available completed NCT00014781
Study of Hepatic Glucose Production and De Novo Lipogenesis in Patients With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT03910881
Technology-enabled Patient Support System for Self-management of CF No drug interventions other Not Available completed NCT03338595
Longitudinal Assessment of Exercise Capacity and Vascular Function in Patients With CF No drug interventions Not Available Not Available completed NCT00219895
Assessment of Inflammatory Mediators (AIM) treatment Not Available completed NCT03125395
A Rollover Safety Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Years and Older With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation No drug interventions treatment 3 completed NCT04018495
STeP IT UP CF: STimulating ImProved Health And Well-being In CysTic Fibrosis No drug interventions supportive_care Not Available completed NCT01285895
Needs in Education for Pulmonary or Cardiopulmonary Transplanted Cystic Fibrosis Patients No drug interventions Not Available Not Available completed NCT03728595
Validation of a Predictive Score for HAST No drug interventions Not Available Not Available completed NCT03278314
Tezacaftor/Ivacaftor Combination Therapy Expanded Access Program for Patients 12 Years of Age and Older With Cystic Fibrosis No drug interventions Not Available Not Available approved_for_marketing NCT01116414
Molecular Phenotypes for Cystic Fibrosis Lung Disease No drug interventions Not Available Not Available completed NCT04798014
HERO-2: Home-Reported Outcomes With CFTR Modulator Therapy No drug interventions Not Available Not Available completed NCT00792714
Pharmacokinetics of Inhaled Mannitol in Cystic Fibrosis Patients No drug interventions treatment 1 completed NCT00458614
Pharmacokinetic Study of Lansoprazole in Cystic Fibrosis No drug interventions treatment 1 completed NCT03391414
Effects of Inhaled Bicarbonate on Airway pH in Cystic Fibrosis No drug interventions basic_science 1 completed NCT04170114
Comparison of the Efficacy of Comprehensive Respiratory Physiotherapy in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis No drug interventions treatment Not Available completed NCT02565914
A Study to Evaluate the Safety and Efficacy of Long Term Treatment With VX-661 in Combination With Ivacaftor in Participants With Cystic Fibrosis Who Have an F508del-CFTR Mutation No drug interventions treatment 3 completed NCT04071314
Evaluating the Alimentary and Respiratory Tracts in Health and Disease (EARTH) Research Program. No drug interventions Not Available Not Available unknown_status NCT00981214
Study of Pancreatic Enzyme Product in Pediatric Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency No drug interventions treatment 3 completed NCT03029455
A Study to Evaluate Safety and Pharmacokinetics of VX-659 in Healthy Subjects and in Adults With Cystic Fibrosis No drug interventions treatment 1 completed NCT02703155
The Use of Home Oral Glucose Tolerance Test Kit in Screening Cystic Fibrosis Related Diabetes No drug interventions screening Not Available unknown_status NCT04400955
A Study of Web and Tablet-based Interactive Audiometry in Adults With CF No drug interventions Not Available Not Available completed NCT05517655
BEGIN Novel ImagiNG Biomarkers No drug interventions diagnostic 4 recruiting NCT02489955
Antibiotic Nephrotoxicity in Adult Patients With Cystic Fibrosis No drug interventions diagnostic Not Available unknown_status NCT01651455
Retrospective Observational Study to Compare Cystic Fibrosis Patients in Two Decades Before and After 2000 No drug interventions Not Available Not Available completed NCT04922255
Cystic Fibrosis and Urinary Incontinence No drug interventions treatment Not Available completed NCT01708655
Sweat Evaporimeter Measurement No drug interventions diagnostic Not Available completed NCT01608555
Tobramycin 300 mg Once-a-day (o.d.) Aerosol in Adults With Cystic Fibrosis No drug interventions treatment 4 completed NCT00256555
Growth Hormone Treatment Study in Children With Cystic Fibrosis treatment 2 / 3 withdrawn NCT01837355
Modulation of Intestinal and Pulmonary Inflammation by Lactobacillus Diet Supplementation in Pediatric Cystic Fibrosis No drug interventions treatment Not Available unknown_status NCT00248755
Assessing Mucociliary Clearance and Airway Liquid Volume in the CF Airway No drug interventions diagnostic Not Available completed NCT03104855
Clearance of 25-hydroxyvitamin D in Cystic Fibrosis No drug interventions diagnostic 1 completed NCT05392855
Symptom Based Performance of Airway Clearance After Starting Highly Effective Modulators for Cystic Fibrosis (SPACE-CF) No drug interventions treatment Not Available recruiting NCT05663255
Effectiveness of CFTR Modulators According to Co-therapy No drug interventions Not Available Not Available not_yet_recruiting NCT00744250
Intraduodenal Aspiration Study to Assess the Bioavailability of Oral Pancrecarb® Compared to Placebo Control No drug interventions supportive_care 4 terminated NCT01353950
Costimulatory Molecules as Biomarkers in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT01885650
The Addition of Non-Invasive Ventilation To Airway Clearance Techniques In Adults With Cystic Fibrosis No drug interventions treatment Not Available terminated NCT04509050
Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children No drug interventions Not Available Not Available recruiting NCT00700050
Modulation by Sex Hormones of Inflammation and Susceptibility to Pseudomonas Aeruginosa in Cystic Fibrosis Airways No drug interventions Not Available Not Available completed NCT04024423
Healthcare-associated Links in Transmission of Nontuberculous Mycobacteria in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT05100823
Validation of Therapeutic Efficacy Targeting the Splicing Variants in Cystic Fibrosis and CFTR Pathologies No drug interventions basic_science Not Available recruiting NCT01880723
Utilizing Exhaled Breathe Condensate Collection to Study Ion Regulation in Cystic Fibrosis No drug interventions basic_science Not Available completed NCT00001223
Diagnosis and Treatment of Patients With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT06526923
A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF) No drug interventions treatment 1 / 2 recruiting NCT00117208
Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis treatment 2 completed NCT02303808
Positive Expiratory Pressure During Inhalation of Hypertonic Saline in Patients With Cystic Fibrosis No drug interventions treatment Not Available completed NCT04503408
A Comparison of Clinical Parameters in With and Without Abnormal Glucose Tolerance. No drug interventions Not Available Not Available completed NCT04884308
Bacille Calmette-Guerin (BCG) Vaccine for Immune Protection Against Infections No drug interventions prevention 2 completed NCT02468908
Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects No drug interventions treatment 1 completed NCT06306508
Effect of Parental Attitude on Functional and Physical Level of Children With Cystic Fibrosis No drug interventions Not Available Not Available recruiting NCT03161808
Rare CFTR Mutation Cell Collection Protocol (RARE) No drug interventions Not Available Not Available recruiting NCT01090908
Evaluation of Ciprofloxacin for Inhalation to Cystic Fibrosis Patients With P. Aeruginosa No drug interventions Not Available Not Available withdrawn NCT05712538
Safety, Tolerability, and Pharmacokinetics of ARCT-032 in Healthy Adult Subjects and Adults With Cystic Fibrosis. No drug interventions treatment 1 recruiting NCT03710538
The Effect of a Pre-meal Snack and/or Exercise on Post-prandial Glycemic Excursions in Adults With Cystic Fibrosis No drug interventions treatment Not Available completed NCT00082238
Increased Gluconeogenesis is One Cause of Cystic Fibrosis Related Diabetes (CFRD) No drug interventions diagnostic Not Available completed NCT01521338
G551D Observational Study- Expanded to Additional Genotypes and Extended for Long Therm Follow up (GOAL-e2) No drug interventions Not Available Not Available completed NCT00823238
Comparison of Antibiotics for Pseudomonas in Early CF No drug interventions treatment 1 completed NCT04354038
Host and Bacterial Mechanisms During Cystic Fibrosis Pulmonary Exacerbations No drug interventions Not Available Not Available active_not_recruiting NCT00788138
Effects of Vitamin D Supplementation on Lung Function in an Acute Pulmonary Exacerbation of Cystic Fibrosis No drug interventions treatment Not Available completed NCT01863238
An Ocular Safety Study of Ivacaftor-Treated Pediatric Patients 11 Years of Age or Younger With Cystic Fibrosis No drug interventions Not Available Not Available completed NCT02605538
Hepatitis B in Cystic Fibrosis and Latent Tuberculosis Respectively No drug interventions prevention Not Available withdrawn NCT02700243
Increase Tolerance for Exercise and Raise Activity Through Connectedness Trial No drug interventions treatment Not Available completed