Cytochrome P-450 Enzyme Inhibitors
- Name
- Cytochrome P-450 Enzyme Inhibitors
- Accession Number
- DBCAT000394
- Description
Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 ENZYMES.
- Drugs
Drug Drug Description (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE Not Available 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP) is a synthetic analogue of meperidine. It is sold as a "synthetic heroin." 6-Deoxyerythronolide B Not Available Abametapir A pediculicide metalloproteinase used topically in the treatment of head lice infection. Abemaciclib A medication used to treat HR+ HER2- advanced or metastatic breast cancer. Abiraterone An antiandrogen used in the treatment of metastatic castration-resistant prostate cancer and metastatic high-risk castration-sensitive prostate cancer. Acalabrutinib A Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. Acebutolol A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults. Acetaminophen An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. Acetazolamide A carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. Acetyl sulfisoxazole Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the... Acoramidis A small molecule transthyretin stabilizer for use in patients with cardiomyopathy caused by transthyretin amyloidosis. Adagrasib A KRAS inhibitor indicated for the treatment of locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer in patients who have received at least one prior systemic therapy. Ademetionine S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as... Agomelatine Agomelatine is indicated to treat major depressive episodes in adults. Albinterferon Alfa-2B Investigated for use/treatment in hepatitis (viral, C). Albuterol A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms. Aldesleukin A recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma. Allicin Allicin has been used in trials studying the treatment of Follicular Lymphoma. Allopurinol A xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies. Almonertinib A third-generation, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) indicated for the treatment of patients with metastatic EGFR T790M mutation-positive non-small cell lung cancer (NSCLC). Alosetron A 5-HT3 antagonist used to treat diarrhea-predominant IBS. Alpelisib Alpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer. This cancer must be hormone receptor (HR)-positive, human epidermal growth factor... Alpibectir Alpibectir is a small molecule drug. Alpibectir is under investigation in clinical trial NCT06748937 (A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With Ethionamide).... Aminophenazone An analgesic drug used to treat acute migraine attacks in combination with ergotamine and caffeine. Amiodarone A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. Amitriptyline A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. Amlodipine A calcium channel blocker used to treat hypertension and angina. Amodiaquine An antimalarial drug. Amoxapine A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression. Amoxicillin A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. Amphetamine A CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Amprenavir A protease inhibitor used to treat HIV infection. Anacaulase A mix of proteolytic enzymes indicated for eschar removal in adults with deep partial thickness and/or full-thickness thermal burns. Anagrelide A platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms. Anastrozole A competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women. Angelica sinensis root Angelica sinensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Antipyrine An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine. Aprepitant A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. Aprocitentan An endothelin receptor antagonist used for the treatment of uncontrolled hypertension in patients inadequately controlled on other treatments. Armodafinil A stimulant used to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea, narcolepsy, or shift work disorder. Arsenic trioxide A chemotherapeutic agent used in the treatment of refractory or relapsed acute promyelocytic leukemia in patients with prior retinoid and anthracycline chemotherapy. Artefenomel Artefenomel has been investigated for the treatment of Malaria. Artenimol For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB13941. Asciminib An inhibitor of ABL/BCR-ABL1 tyrosine kinase for the treatment of patients with Philadelphia chromosome-positive CML, including those with the T315I mutation. Asenapine An atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia. Astemizole A second generation antihistamine used to treat allergy symptoms. Asunaprevir An NS3 protease inhibitor used to treat hepatitis C genotype 1b. Atazanavir An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. Atomoxetine A selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD). Atorvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Atovaquone An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria. Atrasentan An endothelin A receptor antagonist used to reduce proteinuria in patients with primary IgA nephropathy. Avacopan An orally bioavailable complement 5a receptor (C5aR) antagonist for the treatment of severe anti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis. Avapritinib A selective tyrosine kinase inhibitor being investigated for the treatment of multidrug resistant gastrointestinal tumors. Avasimibe Investigated for use/treatment in peripheral vascular disease. AVE9633 Investigated for use/treatment in leukemia (myeloid). Azamulin Azamulin is a small molecule drug. Azamulin has a monoisotopic molecular weight of 478.26 Da. Azelastine A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. Azithromycin A macrolide antibiotic used to treat a variety of bacterial infections. Balaglitazone Balaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2. Baloxavir marboxil A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza. Barnidipine A calcium channel blocker used to treat various forms of hypertension. Belinostat A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). Belumosudil An oral inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK) used in the treatment of chronic graft-versus-host disease (GVHD). Benidipine A synthetic dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. Benzbromarone A uricosuric agent which is taken daily for the prevention of gout flares. Benznidazole A trypanocidal agent used to treat Chagas disease. Bepridil For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). Bergapten Bergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis). Berotralstat An inhibitor of plasma kallikrein used for prophylaxis of angioedema attacks in patients with hereditary angioedema. Besifloxacin A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis. Besigomsin Besigomsin is a small molecule drug. Besigomsin has a monoisotopic molecular weight of 416.18 Da. Bexarotene A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. Bezafibrate A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. Bicalutamide An androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate. Bifonazole An azole antifungal drug used to treat fungal skin infections, such as dermatomycosis. Biperiden A muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs. Birch bark extract A herbal medicinal product used to treat partial thickness wounds. Black cohosh A herbal product indicated in the symptomatic treatment of menopause. Boceprevir A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. Bortezomib A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies. Bosutinib An antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments. Brefeldin A A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity. Brentuximab vedotin A CD30-directed antibody-drug conjugate used to treat various types of lymphoma. Brincidofovir An oral lipid prodrug of cidofovir used in the treatment of human smallpox disease. Bromazepam A short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. Bromocriptine A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. Bryostatin 1 Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease. Buprenorphine A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction. Bupropion A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation. BW-A 58C BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy metabolite in man in vivo and also in human... Cabergoline A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes. Cabozantinib A tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer. Caffeine A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. Candesartan An angiotensin-receptor blocker indicated in the treatment of hypertension. Candesartan cilexetil An angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy. Candicidin Used in the topical treatment of vulvovaginal candidiasis. Cannabidiol An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. Cannabinol Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa. Capecitabine A nucleoside metabolic inhibitor indicated to treat different gastrointestinal, including pancreatic cancer, and breast cancer. Capmatinib A kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Carbamazepine An anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia. Carbazochrome Indicated for capillary and parenchymal hemorrhage (trauma, tonsillectomy, during surgery), intestinal bleeding, and thrombocytopenic purpura. Carbomycin Carbomycin, also called magnamycin, is crystalline macrolide antibiotic. This antibacterial is obtained from Streptomyces halstedii and it presents a large inhibitory effect against Gram-positive bacteria and some Mycoplasma strains. The... Cariprazine An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder. Casimersen An antisense phosphorodiamidate morpholino oligonucleotide used to treat Duchenne muscular dystrophy patients with mutations amenable to exon 45 skipping. Caspofungin An echinocandin used to treat a variety of fungal infections. Cathine Used to decrease appetite. Celecoxib An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Cenobamate A small molecule drug indicated to treat partial onset seizures in adults. Cepeginterferon alfa-2B Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C). Ceritinib An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib. Cerivastatin A statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events. Cethromycin A ketolide antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and atypical bacteria that may be useful for treating several conditions including community-acquired pneumonia, inhalation anthrax, plague, and tularemia. Chamazulene Not Annotated Chloramphenicol A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. Chloroquine An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis. Chlorpheniramine A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. Chlorpromazine A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. Chlorzoxazone A drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions. Cholecalciferol A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. Ciglitazone Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class. Ciglitazone was never used as a medication, but it sparked interest in... Cimetidine A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. Cinacalcet A calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma. Cinchonidine Not Annotated Cinnamon oil Not Annotated Cinoxacin For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and... Ciprofloxacin A second generation fluoroquinolone used to treat various susceptible bacterial infections. Cisapride A medication used to treat heartburn associated with GERD. Cisplatin A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. Citalopram A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression. Clarithromycin A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. Clascoterone An androgen receptor antagonist used for the topical treatment of acne vulgaris in patients 12 years of age and older. Clemastine An antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis. Clevidipine A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. Clinafloxacin Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of... Clindamycin A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria. Clobazam A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome. Clofazimine A riminophenazine antimycobacterial used to treat leprosy. Clofibrate A fibric acid derivative used to treat hypertriglyceridemia and high cholesterol. Clomipramine A tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder. Clonazepam A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures. Cloperidone Cloperidone is a small molecule drug. Cloperidone has a monoisotopic molecular weight of 398.15 Da. Clopidogrel An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. Clotrimazole A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis. Clozapine An atypical or second-generation antipsychotic drug used in treatment-resistant schizophrenia and to decrease suicide risk in schizophrenic patients. Cobalt chloride Not Annotated Cobicistat A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection. Cobimetinib An antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma. Cocaine An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. Colchicine An alkaloid used to treat gout and Familial Mediterranean Fever as well as prevent major cardiovascular events. Coltuximab ravtansine Investigated for use/treatment in lymphoma (non-hodgkin's). Conivaptan An antidiuretic hormone inhibitor used to raise serum sodium levels. Conjugated estrogens A mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis. Crisaborole A non-steroidal topical medication used for the treatment of mild-moderate atopic dermatitis. Crizotinib A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive. Cryptotanshinone Not Annotated Curcumin No approved therapeutic indications. Curcumin sulfate No approved therapeutic indications. Cyclizine An antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo. Cyclosporine A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis. Cyproterone acetate A steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer Dabrafenib A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. Dacomitinib A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution. Dalfopristin An antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes. Danazol A synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts. Danoprevir Danoprevir has been used in trials studying the treatment of Hepatitis C, Chronic. Dapoxetine A selective serotonin reuptake inhibitor used in the treatment of premature ejaculation. Daprodustat A small-molecule hypoxia-inducible factor prolyl hydroxylase inhibitor used for the treatment of anemia in patients with chronic kidney disease. Darifenacin An M3 muscarinic receptor blocker used to treat urinary incontinence. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Dasatinib A tyrosine kinase inhibitor used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia or chronic myeloid leukemia. Daunorubicin An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia. Defactinib An inhibitor of FAK used alongside a MEK1/RAF inhibitor for the treatment of recurrent low-grade serous ovarian cancer. Deferasirox An iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin. Delavirdine A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. Deltamethrin Not Annotated Deramciclane Investigated for use/treatment in anxiety disorders. Desipramine A tricyclic antidepressant used in the treatment of depression. Desmethylprodine Desmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine. It has been listed as a Schedule I controlled drug in the United States, and thus... Desogestrel A synthetic progestin used in contraception, often in combination with ethinyl estradiol. Desvenlafaxine An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. Deutivacaftor A CFTR potentiator used to treat cystic fibrosis in patients with responsive mutations (e.g. F508del). Dexamethasone A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. Dexamethasone acetate Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions. Developed in 1957, dexamethasone is... Dexamethasone isonicotinate Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention. Dexchlorpheniramine A chlorpheniramine enantiomer antihistamine indicated in the treatment of sunburns, insect bites, and allergic reactions of the skin. Dexchlorpheniramine maleate A first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema. Dexfenfluramine For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet Dexlansoprazole A proton pump inhibitor used to treat erosive esophagitis, heartburn, and gastroesophageal reflux disease (GERD). Dexloxiglumide For the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD). Dexmedetomidine An alpha-2 agonist used for sedation during various procedures. Dextropropoxyphene An opioid analgesic used to treat mild to moderate pain. Diacerein An slow-onset anthraquinone IL-1 inhibitor used in the treatment of degenerative joint diseases like osteoarthritis. Diazepam A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. Diazoxide A non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions. Diclofenac An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Diethylstilbestrol Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery. Difloxacin Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced... Dihydralazine Dihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals). Dihydroergotamine An ergot alkaloid used in the acute treatment of migraine headache and cluster headache. Diltiazem A calcium channel blocker used to treat hypertension and to manage chronic stable angina. Dimethyl sulfoxide A reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer. Diosmin A citrus flavonoid medication used to support vascular health. Diphenhydramine A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. Dirithromycin An antibiotic used to treat a variety of respiratory, skin, and other infections. Disulfiram A carbamate derivative used to treat alcohol addiction. Ditiocarb A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM. Ditiocarb zinc Ditiocarb Zinc is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6... Docetaxel A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. Doconexent An omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. Doramectin Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in... Dordaviprone A protease inhibitor used to treat diffuse midline glioma with a H3 K27M mutation. Dosulepin A tricyclic antidepressant commonly used only in patients for whom alternative therapies are ineffective due to its toxicity potential. Dovitinib Investigated for use/treatment in multiple myeloma and solid tumors. Doxepin A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. Doxorubicin A medication used to treat various cancers, including AIDS-associated Kaposi's Sarcoma and metastatic cancers. Doxycycline A tetracycline antibiotic used to treat a wide variety of bacterial infections. Dronabinol A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. Dronedarone An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation. Duloxetine A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. Econazole A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor. Edetate calcium disodium anhydrous A chelating agent used to treat lead poisoning. Edetate disodium anhydrous A polyvalent ion chelator indicated for emergency treatment of hypercalcemia and digitalis toxicity associated ventricular arrhythmias. Efavirenz A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. Efonidipine For the treatment of hypertension. Elagolix A gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis. Elbasvir An antiviral and NS5A inhibitor used to treat hepatitis C infections. Elexacaftor A small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation. Eliglustat A glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers. Elinzanetant A selective, dual neurokinin 1 (NK-1) and 3 (NK-3) receptor antagonist used to treat vasomotor symptoms associated with menopause. Ellagic acid Ellagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines. Eltrombopag A thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies. Elvitegravir An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Enasidenib An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. Encorafenib A kinase inhibitor used to treat unresectable or metastatic melanoma with BRAF mutations. Enmetazobactam A beta-lactamase inhibitor used to treat complicated urinary tract infections in combination with cefepime. Enoxacin For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria... Enrofloxacin Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant... Ensitrelvir Ensitrelvir is indicated for post-exposure prophylaxis of coronavirus disease 2019 (COVID-19) in adults and adolescents 12 years of age and older following contact with an individual who has COVID-19. Entacapone A selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson's disease. Enzalutamide A second-generation androgen receptor inhibitor used to treat castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer. Epinastine An H1 receptor antagonist used to prevent itching in allergic conjunctivitis. Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Epofolate Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target... Epothilone D Investigated for use/treatment in colorectal cancer, lung cancer, breast cancer, solid tumors, and prostate cancer. Eprinomectin Not Annotated Erdafitinib A fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma. Ergometrine An ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony. Ergotamine An alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. Erlotinib An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers. Erythromycin A macrolide antibiotic used to treat and prevent a variety of bacterial infections. Escitalopram A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). Eslicarbazepine An antiepileptic indicated as a monotherapy or adjunct therapy in the treatment of epilepsy. Eslicarbazepine acetate An anticonvulsant agent used as an adjunct to treat partial-onset seizures in patients with inadequate clinical response to conventional antiepileptic therapy. Esomeprazole A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion. Estradiol An estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate. Estradiol acetate An estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause. Estradiol benzoate An estrogen indicated in combination with progesterone for the treatment of irregular menstruation. Estradiol cypionate An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism. Estradiol dienanthate An estrogen used in some combined hormonal oral contraceptives. Estradiol valerate An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception. Estrone sulfate An estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders. Ethambutol An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB). Ethanol For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical... Ethinylestradiol An estradiol used as a contraceptive. Etoposide A podophyllotoxin derivative used to treat testicular and small cell lung tumors. Etoricoxib A selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis. Etravirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. Etripamil An L-type calcium channel blocker used to convert acute symptomatic episodes of paroxysmal supraventricular tachycardia to sinus rhythm in adults. Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Everolimus A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies. Ezetimibe A cholesterol absorption inhibitor used to lower total cholesterol, LDL-C, Apo-B, and non-HDL-C in primary hyperlipidemia and familial cholesterolemia. Famotidine A histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. Favipiravir An antiviral used to manage influenza, and that has the potential to target other viral infections. Fedratinib Fedratinib is indicated for the treatment of adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis. Felbamate An anticonvulsant used to treat severe epilepsy. Felodipine A calcium channel blocker used to treat hypertension. Fenfluramine Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures. Fennel Not Annotated Fenofibrate A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. Fenvalerate Not Annotated Ferroheme Not Annotated Fexinidazole An orally bioavailable 2-substituted 5-nitroimidazole used to treat early- and late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense. Fidaxomicin A macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection. Flecainide A class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT). Floxuridine An antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy. Fluconazole A triazole antifungal used to treat various fungal infections including candidiasis. Flumequine Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections. Flunitrazepam A benzodiazepine used to manage anxiety disorders and insomnia. Fluorouracil A pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment. Fluoxetine A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. Fluphenazine A phenothiazine used to treat patients requiring long-term neuroleptic therapy. Flurazepam A long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. Flurithromycin Not Annotated Fluticasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses, asthma, and COPD. Fluticasone furoate An inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis. Fluticasone propionate A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis. Fluvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Fluvoxamine A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. Fomepizole An inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fosamprenavir An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection. Fosaprepitant An antiemetic drug used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting caused by chemotherapy. Fosfluconazole Fosfluconazole is a small molecule drug. Fosfluconazole has a monoisotopic molecular weight of 386.07 Da. Fosnetupitant A medication used in combination with others to prevent chemotherapy associated nausea and vomiting. Fostamatinib A spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment. Furafylline Furafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline. Fusidic acid A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Garenoxacin Investigated for use/treatment in bacterial infection. Garlic oil Not Annotated Gatifloxacin A fourth generation fluoroquinolone used to treat a wide variety of infections in the body. Gefitinib A tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria. Gemfibrozil A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. Gemifloxacin A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria. Genistein Currently Genistein is being studied in clinical trials as a treatment for prostate cancer. Gestodene Gestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol... Ginkgo biloba A herbal supplement found in over-the-counter or unapproved homeopathic products for various health conditions, such as cognitive, neurodegenerative, cardiovascular, and reproductive health disorders. Ginsenoside C Not Available Givinostat A histone deacetylase inhibitor indicated for the treatment of Duchenne Muscular Dystrophy (DMD). Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. Glyburide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Glycerol phenylbutyrate A nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions. Goldenseal Not Annotated GPI-1485 Investigated for use/treatment in erectile dysfunction and parkinson's disease. Grapefruit An extract from Grapefruit used in allergy testing. Grazoprevir An antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections. Grepafloxacin A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections. Guaiazulen Not Annotated Halofantrine An antimalarial used for the treatment of severe malaria. Haloperidol An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. Hippuric acid Not Annotated Histamine An ingredient of topical drugs for the relief of joint pain or muscle aches and pains. Homochlorcyclizine Not Annotated Human placenta hydrolysate Not Annotated Hydralazine An antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia . Hydrastine Not Annotated Hydrastinine Not Annotated Hydroxychloroquine An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus. Hydroxyurea An antimetabolite used to treat sickle cell anemia crisis, resistant chronic myeloid leukemia, and Locally advanced squamous cell carcinomas of the head and neck (excluding the lip). Hydroxyzine An antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria. Ibrexafungerp A triterpene antifungal indicated in the treatment of vulvovaginal candidiasis and prevention of recurrent vulvovaginal candidiasis in post-menarchal patients. Ibuprofen An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. Idelalisib An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). Ifosfamide An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma. Imatinib A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. Imipramine A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. Imlunestrant An estrogen receptor antagonist used to treat estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, estrogen receptor-1 (ESR1)-mutated advanced or metastatic breast cancer in adults with previous endocrine therapy. Indalpine Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse... Indinavir A protease inhibitor used to treat HIV infection. Indisulam Investigated for use/treatment in lung cancer. Indomethacin A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. Interferon alfa An immunomodulator used to treat hepatitis B and C as well as certain types of cancer including cutaneous T-cell lymphoma and renal cell carcinoma. Interferon alfa-2a A form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses. Interferon alfa-2b A form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi's sarcoma. Interferon alfa-2c Interferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma). Interferon alfa-n1 A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus. Interferon alfa-n3 A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus. Interferon alfacon-1 A recombinant interferon similar the interferon alfa subtype which is used to treat hepatitis C infections. Interferon beta-1a A form of recombinant human interferon used to slow disease progression and reduce the frequency of clinical symptoms in patients who have relapsing multiple sclerosis. Interferon beta-1b A form of recombinant human interferon used to slow the progression of relapsing multiple sclerosis and to reduce the frequency of clinical symptoms. Interferon gamma-1b A form of recombinant human interferon used to treat infections associated with chronic granulomatous disease and to slow the progression of severe malignant osteopetrosis. Ipriflavone Not Annotated Iproniazid For the treatment of depression (originally intended to treat tuberculosis). Irbesartan An angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure. Irinotecan A topoisomerase inhibitor used to treat metastatic carcinoma of the colon or rectum and pancreatic adenocarcinoma. Isavuconazole Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of... Isavuconazonium A triazole antifungal used for the treatment of invasive aspergillosis and mucormycosis. Isoliquiritigenin Isoliquiritigenin is a precursor to several flavonones in many plants. Isoniazid An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. Isosorbide dinitrate A vasodilator used to treat angina in coronary artery disease. Isradipine A dihydropyridine calcium channel blocker used for the treatment of hypertension. Itraconazole A triazole antifungal agent used to treat various fungal infections, such as blastomycosis and onychomycosis. Ivacaftor A cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication. JPC-3210 JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant Plasmodium falciparum lines, low cytotoxicity, potent in vivo efficacy against murine... Kava Not Available Ketazolam A long-acting benzodiazepine used to manage anxiety and insomnia. Ketoconazole A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. Ketoprofen An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain. Kitasamycin Kitasamycin is a macrolide antibiotic derived from Streptomyces kitasatoensis. KOS-1584 Investigated for use/treatment in solid tumors. Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Landiolol A rapid-acting selective beta-blocker used to reduce ventricular rate in supraventricular tachycardia in adults. Lanreotide A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly. Lansoprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Lapatinib An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-positive breast cancer in patients who received prior chemotherapeutic treatments. Laromustine Investigated for use/treatment in brain cancer, cancer/tumors (unspecified), colorectal cancer, leukemia (lymphoid), leukemia (myeloid), lung cancer, myelodysplastic syndrome, pediatric indications, and solid tumors. Lasmiditan An oral 5HT1F agonist used for the acute treatment of migraine headache with or without aura. Lazertinib A tyrosine kinase inhibitor used in combiantion with amivantamab to treat non-small cell lung cancer with EGFR mutations. Leflunomide A pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis. Lemborexant A dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia. Lenacapavir A first-in-class capsid inhibitor being investigated for use in HIV-1 treatment. Leniolisib A phosphoinositide 3-kinase-delta inhibitor that is used to treat activated phosphoinositide 3-kinase delta syndrome. Lenvatinib A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. Lercanidipine A calcium channel blocker for the management of hypertension. Lestaurtinib Investigated for use/treatment in pancreatic cancer, prostate cancer, and leukemia (myeloid). Letermovir An antiviral medication used for prophylaxis in adult transplant recipients at risk of cytomegalovirus (CMV) infection and disease. Letrozole An aromatase inhibitor used to treat breast cancer in postmenopausal women. Levofloxacin A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague. Levoketoconazole One of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing's syndrome. Levosalbutamol A beta-2 adrenergic receptor agonist used to treat COPD and asthma. Levothyroxine A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. Licofelone For the management of osteoarthritis. Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Lifitegrast A medication used to treat dry eye disease. Limnetrelvir Limnetrelvir is a small molecule drug. The usage of the INN stem '-trelvir' in the name indicates that Limnetrelvir is a antiviral 3CL protease inhibitor. Limnetrelvir has a monoisotopic molecular... Linagliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Linerixibat An ileal bile acid transporter (IBAT) inhibitor indicated for the treatment of cholestatic pruritus in adult patients with primary biliary cholangitis. Linzagolix A selective gonadotropin-releasing hormone (GnRH) receptor antagonist used for the symptomatic treatment of uterine fibroids. Liotrix May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic... Lobeglitazone Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use... Lomefloxacin A fluoroquinolone used to prevent and treat a wide variety of infections in the body. Lomitapide A microsomal triglyceride transfer protein inhibitor used to lower cholesterol associated with homozygous familial hypercholesterolemia (HoFH), reducing risk of cardiovascular events such as myocardial infarction and stroke. Lomustine An alkylating agent used as a part of chemotherapeutic regimens for the treatment of primary and metastatic brain tumors as well as refractory or relapsed Hodgkin's disease in addition to surgical and/or radiotherapeutic treatments. Lonafarnib A potent farnesyl transferase inhibitor used to reduce mortality associated with Hutchinson-Gilford progeria syndrome (HGPS) and other progeroid laminopathies. Lonapegsomatropin A human growth hormone indicated in the treatment of growth failure due to inadequate endogenous growth hormone secretion. Loperamide A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis. Lopinavir An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. Loratadine A second generation antihistamine used to manage the symptoms of allergic rhinitis. Lorcaserin A serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities. Lorlatinib An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. Lorvotuzumab mertansine Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others. Losartan An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke. Luliconazole A topical antifungal agent used to treat fungal infections. Lumacaftor A protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene. Lumasiran Lumasiran is an interfering RNA that silences hydroxyacid oxidase 1 for the treatment of primary hypoxaluria type 1. Lumefantrine An antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. Lynestrenol A progestin used for contraception and in the treatment of menstrual disorders. Madecassic acid Not Annotated Mafosfamide Mafosfamide has been used in trials studying the treatment of Lymphoma, Leukemia, Meningeal Neoplasm, and Brain and Central Nervous System Tumors. Manidipine A dihydropyridine calcium channel blocker used to treat hypertension. Maralixibat An ileal bile acid transporter inhibitor indicated to treat cholestatic pruritus in patients with Alagille syndrome. Mavorixafor A CXC chemokine receptor 4 antagonist used to treat WHIM syndrome. Medical Cannabis The use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical... Medroxyprogesterone acetate A progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty. Mefenamic acid An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. Mefloquine An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax. Melperone An atypical butyrophenone antipsychotic used to treat sleep disorders, confusion, and psychomotor dysfunction associated with geriatric, psychiatric, and alcohol-dependent patients. Memantine An NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's. Menadione The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. Mephenytoin A phenylhydantoin used to treat refractory partial epilepsy. Mepyramine An antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. Mequitazine For the treatment of Hay fever, urticaria (hives) and allergic rhinitis Metacetamol Metacetamol is a small molecule drug. Metacetamol has a monoisotopic molecular weight of 151.06 Da. Methadone An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. Methimazole A thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism. Methotrimeprazine A phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder. Methoxsalen A furocoumarin used to treat psoriasis and vitiligo. Methsuximide A succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures. Methylene blue An oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia. Methylergometrine An ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery. Methylone Methylone is under investigation in clinical trial NCT05741710 (A Study to Assess the use of Methylone in the Treatment of PTSD). Metoclopramide An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. Metoprolol A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction. Metronidazole A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. Metyrapone A steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function. Mexiletine A class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. Mibefradil For the treatment of angina and high blood pressure. Miconazole An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis. Midazolam A short-acting benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. Midecamycin A macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria. Midostaurin An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). Mifentidine Mifentidine is a small molecule drug. The usage of the INN stem '-tidine' in the name indicates that Mifentidine is a histamine- H2-receptor antagonist, cimetidine derivative. Mifentidine has a monoisotopic... Mifepristone A cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation. Milnacipran A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder. Miocamycin Miocamycin is a macrolide type antimicrobial . This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia . It has shown to... Mirabegron A beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity. Miricorilant Miricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent Weight Gain While Taking... Mirtazapine A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite. Mitemcinal Investigated for use/treatment in gastroparesis and irritable bowel syndrome (IBS). Mitoxantrone A chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis. Mizolastine A second-generation non-sedating antihistamine used to treat symptoms of allergic rhinoconjunctivitis and urticaria. Moclobemide A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. Modafinil A stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder. Momelotinib A Janus Kinase inhibitor used to treat intermediate or high-risk myelofibrosis. Mometasone A corticosteroid with no indications. Mometasone furoate A corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus. Montelukast A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. Moxifloxacin A fluoroquinolone antibiotic used to treat various bacterial infections. Nabilone A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. Nabiximols In Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have... Nafimidone Nafimidone is a small molecule drug. Nafimidone has a monoisotopic molecular weight of 236.09 Da. Nafithromycin Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP). Nalidixic acid A quinolone antibiotic used to treat urinary tract infections. Naloxegol A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. Naloxone An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. Naringin Not Annotated Nefazodone An antidepressant used in the treatment of depression. Nelfinavir A viral protease inhibitor used in the treatment of HIV infection. Nemonoxacin Investigated for use/treatment in bacterial infection and pneumonia. Netoglitazone Netoglitazone (MCC-555) is a hypoglycemic agent. Netupitant An antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy. Nevirapine A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. Niacin A B vitamin used to treat hypertriglyceridemia and pellagra. Nicardipine A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. Niclosamide An anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children. Nicotinamide An ingredient found in a variety of cosmetic products. Nicotine A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. Nifedipine A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. Nilotinib A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib. Nilutamide An antineoplastic hormone used to treat prostate cancer. Nilvadipine A calcium channel blocker used to manage arterial hypertension. Nirmatrelvir An oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19. Nitisinone A hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1) and Alkaptonuria, which cause intolerance to tyrosine containing foods. Nitrazepam A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures. Nitric Oxide A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates. Nivasorexant Nivasorexant is a small molecule drug. The usage of the INN stem '-orexant' in the name indicates that Nivasorexant is a orexin receptor antagonist. Nivasorexant has a monoisotopic molecular weight... Nix-0699 Not Annotated Norfloxacin A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine. Nortriptyline A tricyclic antidepressant used in the treatment of depression. Noscapine A non-sedating isoquinoline alkaloid used primarily for its antitussive properties. Obeticholic acid A bile acid analog and farnesoid X receptor agonist used to treat primary biliary cholangitis in adult patients with inadequate clinical response or intolerance to UDCA. Octreotide A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors. Ofloxacin An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract. Olanzapine An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders. Olaparib A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer. Oleandomycin Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus. Olorofim Olorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects). Omeprazole A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. Ondansetron A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively. Opelconazole Not Annotated Opicapone A catechol-O-methyltransferase inhibitor used as an adjunct treatment for Parkinson's Disease in adults currently receiving levodopa and a dopa decarboxylase inhibitor. Orbifloxacin Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs. Oritavancin An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria. Orphenadrine A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. Osilodrostat An oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism. Osimertinib A tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma. Ospemifene A non-hormonal estrogen receptor modulator (SERM) used to treat moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. OSU-6162 OSU-6162 is under investigation in clinical trial NCT05641623 (OSU6162 as Add-on in Ssri/snri-resistant Depression). Oxamniquine For treatment of Schistosomiasis caused by Schistosoma mansoni Oxandrolone An androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis. Oxcarbazepine An anti-epileptic used in the treatment of partial-onset seizures. Oxethazaine An antacid used to treat gastritis, peptic ulcer disease, heartburn, esophagitis, hiatus hernia, and anorexia. Oxprenolol A non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety. Oxybutynin An antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void. Oxymetholone An anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias. P-57AS3 Investigated for use/treatment in obesity. Pacritinib A kinase inhibitor used for the treatment of primary and secondary myelofibrosis in adult patients with significantly reduced platelet counts. Palbociclib An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer. Paltusotine A somatostatin receptor agonist used to treat acromegaly in adults whose surgery is not an option or has not been effective. Panobinostat A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents. Pantoprazole A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. Paramethasone For the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary... Paroxetine A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. Pasireotide A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate. Patupilone Investigated for use/treatment in ovarian cancer, lung cancer, brain cancer, breast cancer, and gastric cancer. Pazopanib An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy. Pazufloxacin Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol). Pefloxacin An antibiotic used to treat a variety of bacterial infections. Peginterferon alfa-2a A modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses. Peginterferon alfa-2b A purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers. Peppermint oil An ingredient used in a variety of natural health products and is not an approved medication. Perampanel A non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy. Pergolide A long-acting dopamine agonist that is uncommonly used for the management of Parkinson's disease, due to the risk for cardiac valvulopathy. Perhexiline For the management of severe angina pectoris. Perphenazine A phenothiazine used to treat schizophrenia as well as nausea and vomiting. Pexidartinib An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. Phencyclidine A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like... Phenelzine A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression. Phenylbutazone An NSAID used to treat backache and ankylosing spondylitis. Phenylbutyric acid An agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy. Phenytoin An anticonvulsant drug used in the prophylaxis and control of various types of seizures. Phloxine B For use in dental disclosing products, allowing for highlighting of bacterial placques. Pibrentasvir A Hepatitis C NS5A inhibitor used to treat Hepatitis C. Pilocarpine A muscarinic agonist used to treat dry mouth and various ophthalmic conditions, such as presbyopia, increased intraocular pressure, and angle-closure glaucoma. Pimozide An antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette's Disorder. Pindolol A beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation. Pioglitazone A thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. Pipemidic acid A quinolone antibiotic indicated in the treatment of susceptible urinary tract infections. Piperaquine For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638. Piperine Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders. Piperonyl butoxide A pesticide used as a potentiator ingredient in the treatment of pediculosis (head lice, body lice or crabs) to boost efficacy of treatment. Pipotiazine An antipsychotic indicated for the management of chronic, non-agitated schizophrenic patients. Pirfenidone An agent used for the treatment of idiopathic pulmonary fibrosis (IPF). Piroxicam An NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis. Pirtobrutinib A kinase inhibitor used to treat relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy. It is also used in adults with relapsed or refractory CLL/SLL who have previously received a covalent BTK inhibitor. Pitolisant An antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults. Poloxamer 188 A medication used to clean wounds. Polysorbate 80 It is used as a solubilizer, antimicrobial preservative and disinfectant . Posaconazole A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. Pralsetinib A RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer. Pranlukast A leukotriene receptor antagonist for the treatment of allergic rhinitis and asthma symptoms. Prasterone A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy. Primaquine An antimalarial indicated to prevent relapse of vivax malaria. Probenecid A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia. Progesterone A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. Proguanil A medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria. Promazine A phenothiazine used to manage schizophrenia. Promethazine A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. Propacetamol Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy. Propafenone A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias. Propofol A medication used in general anesthesia and for sedation. Propranolol A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. Prulifloxacin A broad-spectrum fluoroquinolone antibiotic used to treat a variety of susceptible bacterial infections. Pyrimethamine An antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria. Quazepam A long-acting benzodiazepine used to manage insomnia. Quercetin A natural flavonoid found in foods and natural supplement products. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Quinine An alkaloid used to treat uncomplicated Plasmodium falciparum malaria. Quinupristin An antibiotic agent used in the treatment of serious vancomycin-resistant Enterococcus faecium bacteremia as well as complicated skin and skin structure infections. Rabeprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Raloxifene A selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women. Ranitidine A histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis. Ranolazine An anti-anginal drug used for the treatment of chronic angina. Reboxetine A drug used for the acute treatment of major depression and for maintenance therapy of depression. Regorafenib A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma. Relacorilant A selective glucocorticoid receptor antagonist that reverses glucocorticoid-mediated anti-apoptotic signaling to restore chemosensitivity in platinum-resistant ovarian, fallopian tube, and primary peritoneal cancers. Remacemide Investigated for use/treatment in epilepsy, huntington's disease, and parkinson's disease. Remdesivir A nucleoside analog used to treat RNA virus infections including COVID-19. Remibrutinib A Bruton's tyrosine kinase inhibitor used to treat chronic spontaneous urticaria in adults. Remoxipride An discontinued atypical antipsychotic selective for dopamine D2 receptors. Repotrectinib A tyrosine kinase inhibitor used to treat locally active or metastatic non-small cell lung cancer Resmetirom A thyroid hormone receptor-beta agonist used to treat noncirrhotic nonalcoholic steatohepatitis (NASH) with moderate to advanced liver fibrosis in adults. Resveratrol Being investigated for the treatment of Herpes labialis infections (cold sores). Revumenib A small molecule menin inhibitor for the treatment of relapsed/refractory leukemia with KMT2A translocation. Rhein No approved indication. Ribociclib A cyclin-dependent kinase inhibitor used to treat HR+, HER2- breast cancer. Ridaforolimus Investigated for use/treatment in solid tumors, sarcoma, cancer/tumors (unspecified), endometrial cancer, prostate cancer, and bone metastases. Rifampin An antibiotic used alone or in combination with other antimicrobial drugs to treat tuberculosis and asymptomatic carriers of Neisseria meningitidis. Rifamycin An antibacterial used to treat traveler's diarrhea. Rilpivirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). Rilzabrutinib A kinase inhibitor used to treat persistent or chronic immune thrombocytopenia (ITP) who have had an insufficient response to a previous treatment. Rimegepant An oral CGRP receptor antagonist used for the acute treatment of migraines with or without aura in adults. Ripretinib A kinase inhibitor used to treat advanced gastrointestinal stromal tumor (GIST). Risperidone A second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression. Ritanserin Ritanserin has been used in trials studying the treatment of Cocaine-Related Disorders. Ritlecitinib A kinase inhibitor used to treat severe alopecia areata in adults and adolescents 12 years and older. Ritonavir An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. Rivoglitazone Rivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo Co. Rizatriptan A triptan used to treat migraines with or without aura. Rofecoxib A COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks. Rokitamycin Not Annotated Rolapitant A neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy. Ropeginterferon alfa-2b A mono-pegylated type I interferon used to treat polycythemia vera. Rosiglitazone A thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. Rosoxacin For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosuvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Rotigotine A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome. Roxithromycin An antibiotic used to treat a variety of susceptible bacterial infections. Rucaparib A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults. Rufinamide An antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS). Rufloxacin A fluoroquinolone antibiotic indicated in the treatment of susceptible respiratory infections and uncomplicated cystitis. Rutin A flavonoid found in over-the-counter vitamin supplements. Safinamide A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes. Sagopilone Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is... Salmeterol A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. Saquinavir An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. Saracatinib Saracatinib has been investigated for the treatment of Cancer, Osteosarcoma, Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer. Sarafloxacin Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada. Sarilumab A monoclonal antibody used to treat moderate to severe rheumatoid arthritis who have responded poorly or are intolerant of other DMARDs. Saw palmetto Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Sebetralstat A plasma kallikrein inhibitor indicated for the oral on-demand treatment of acute hereditary angioedema attacks in adults and pediatric patients aged 12 years and older, shown in phase 3 trials to provide faster symptom relief, reduced attack severity, and quicker resolution compared to placebo. Secnidazole A nitroimidazole antibiotic used to treat bacterial vaginosis. Selamectin Selamectin is a topical parasiticide and antihelminthic used on dogs and cats to treat and prevent infections of heartworms, fleas, ear mites, sarcoptic mange, and certain types of ticks in... Selegiline A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. Selpercatinib A RET receptor tyrosine kinase inhibitor for the treatment of RET-driven non-small cell lung cancer, medullary thyroid cancer, and thyroid cancer in appropriate patient populations. Seproxetine Seproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an... Seratrodast Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. Sertraline A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. Sevabertinib A HER2 kinase inhibitor used to treat non-squamous non-small cell lung cancer with HER2 (ERBB2) tyrosine kinase domain (TKD) activating mutations. Seviteronel Seviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer. Sildenafil A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. Siltuximab An interleukin antagonist used to treat multicentric Castleman's disease (MCD) in patients who are HIV and HHV-8 negative. Simeprevir A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. Simvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke. Sitafloxacin A fluoroquinolone antibiotic indicated in the treatment of susceptible bacterial infections. Sitaxentan Investigated for use/treatment in pulmonary hypertension, connective tissue diseases, hypertension, and congestive heart failure. SN-38 Investigated for use/treatment in colorectal cancer. Sofpironium A topical anticholinergic used to treat primary axillary hyperhidrosis. Solithromycin Investigated for the treatment of community-acquired pneumonia (CAP). Somapacitan A human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency. Somatostatin A natural peptide hormone used to treat acute bleeding from esophageal varices, gastrointestinal ulcers, and gastritis; prevent pancreatic complications after surgery; and restrict secretions of the upper intestine, pancreas, and biliary tract. Somatotropin A recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults. Sonrotoclax A selective oral BCL-2 inhibitor indicated for relapsed or refractory mantle cell lymphoma who have already tried a BTK inhibitor. Sophora flavescens root Not Annotated Sorafenib A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma. Sotagliflozin An orally administered dual SGLT1/2 inhibitor used alongside insulin to improve glycemic control in patients with type 1 diabetes mellitus. Sparfloxacin A fluoroquinolone antibiotic used to treat bacterial respiratory infections and sinusitis. Sparsentan An endothelin and angiotensin II receptor antagonist indicated to reduce proteinuria in adults with primary immunoglobulin A nephropathy at risk of rapid disease progression. Sparteine Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category... Spiramycin A macrolide antimicrobial agent used in the treatment of various bacterial infections. Spironolactone An aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism. St. John's Wort An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety. Stiripentol An antiepileptic agent used in combination with other anticonvulsants to treat seizures associated with Dravet syndrome. Sulconazole A topical antifungal agent used for the treatment of tinea cruris, tinea corporis, and tinea versicolor caused by susceptible fungal strains. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Sulfadimethoxine For use in the treatment of infections. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Sulfamethoxazole An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. Sulfamoxole For the treatment of bacterial infection. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Sulfaphenazole For the treatment bacterial infections. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Sulfinpyrazone A platelet inhibitory and uricosuric agent used to inhibit thrombotic and embolic processes and to manage the chronic phases of gout . Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Sulforaphane Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli. Sunitinib A receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). Suprofen An NSAID used to prevent pupil constriction in ocular surgery. Suvorexant A orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance. Suzetrigine A sodium channel blocker used to treat moderate to severe acute pain in adults. Tabimorelin Tabimorelin is a small molecule drug. The usage of the INN stem '-relin' in the name indicates that Tabimorelin is a pituitary hormone-release stimulating peptide. Tabimorelin has a monoisotopic molecular... Tacrolimus A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. Talarozole Talarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation. Taletrectinib A small molecule ROS1 inhibitor for use in patients with advanced forms of ROS1-positive non-small cell lung cancer. Tamoxifen A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women. Tanshinone I Not Annotated Tasisulam Tasisulam has been used in trials studying the treatment and basic science of Melanoma, Lymphoma, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others. Technetium Tc-99m ciprofloxacin Investigated for use/treatment in infectious and parasitic disease (unspecified). Tecovirimat An antiviral medication used to treat smallpox, monkeypox, and cowpox. Tegaserod A serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men. Telaprevir An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. Telisotuzumab vedotin An chemotherapeutic antibody-drug conjugate comprising a c-Met-directed antibody with a microtubule-disrupting small molecule payload. Telithromycin An ketolide used to treat community acquired pneumonia of mild to moderate severity. Telmisartan An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. Telotristat ethyl A tryptophan hydroxylase inhibitor that is used to treat carcinoid syndrome diarrhea. Temafloxacin For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections. Temsirolimus A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR. Teniposide A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia. Tepotinib An oral tyrosine kinase inhibitor targeted against MET for the treatment of metastatic non-small cell lung cancer in patients exhibiting MET exon 14 skipping mutations. Terbinafine An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections. Terfenadine An antihistamine for the treatment of allergy symptoms. Teriflunomide A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. Tesmilifene Intended for the treatment of various forms of cancer. Testosterone cypionate An androgen used to treat low or absent testosterone. Testosterone enanthate An androgen used to treat low or absent testosterone. Testosterone undecanoate An androgen indicated for testosterone replacement therapy in adult males with primary hypogonadism and hypogonadotropic hypogonadism. Tetracycline An antibiotic used to treat a wide variety of susceptible infections. Tezacaftor A CFTR corrector used to treat cystic fibrosis in patients with susceptible mutations (e.g. F508del). Thalidomide A medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum. Thiabendazole A benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections. Thiopental A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. Thioridazine A phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder. Thiotepa An alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas. Thiothixene An antipsychotic indicated for the management of schizophrenia. Tiamulin Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry. Ticagrelor A P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death. Ticlopidine A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). Tienilic acid For the treatment of hypertension. Tildipirosin Tildipirosin is a veterinary antibiotic. Tilidine A synthetic opioid indicated in the treatment of severe pain. Tioconazole An imidazole antifungal used to treat vulvovaginal candidiasis. Tipranavir A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. Tirbanibulin A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp. Tocainide An orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias. Tofisopam For the treatment of anxiety and alcohol withdrawal. Tolbutamide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Tolcapone A catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease. Topiramate An anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. Topiroxostat Indicated for the treatment of gout and hyperurcemia in Japan. Topotecan An antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer. Torasemide A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease. Toremifene A first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers. Tovorafenib A type II RAF inhibitor used to treat pediatric low-grade glioma with BRAF gene mutations. Tradipitant A substance P receptor antagonist used to prevent motion-induced vomiting in adults. Trametinib A kinase inhibitor used alone or in combination with dabrafenib to treat patients with cancers with specific BRAF mutations, such as melanoma and non-small cell lung cancer. Tranylcypromine A monoamine oxidase inhibitor used to treat major depressive disorder. Trazodone A serotonin uptake inhibitor used to treat major depressive disorder. Treosulfan A DNA alkylating agent used in the context of myeloablative conditioning prior to allogeneic hemoatopoietic stem cell transplantation. Triazolam A benzodiazepine used for short term treatment of insomnia. Trichloroethylene Trichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. It has been sold under a variety of... Triclabendazole An anthelmintic drug used to treat fascioliasis. Trilaciclib A CDK4 and CDK6 inhibitor to reduce the risk of chemotherapy induced myelosuppression. Trimethoprim An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. Tripelennamine A histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold. Trofinetide A drug used to treat Rett syndrome in children and adults. Troglitazone For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise. Troleandomycin For the treatment of bacterial infection. Trospium An antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). Trovafloxacin An antibiotic used to treat gonorrhea and chlamydia. Tucatinib A kinase inhibitor used to treat certain types of unresectable/metastatic HER-2 positive breast cancer. Ubrogepant An oral CGRP antagonist used in the acute treatment of migraine with or without aura. Vadadustat An oral hypoxia-inducible factor prolyl-hydroxylase inhibitor used to treat symptomatic anemia associated with chronic kidney disease in adults on chronic maintenance dialysis. Valdecoxib A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. Valproic acid An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. Valsartan An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors. Vapreotide For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea. Vardenafil A phosphodiesterase 5 inhibitor used to treat erectile dysfunction. Vayarin ADHD in children, hypertriglyceridemia . Vemurafenib A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. Venetoclax A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia. Venlafaxine A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder. Vepdegestrant An oral proteolysis-targeting chimera (PROTAC) estrogen receptor degrader used to treat adults with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, ESR1-mutated advanced or metastatic breast cancer. Verapamil A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. Vernakalant An antiarrhythmic medication used to treat patients with atrial fibrillation. Vilazodone An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. Viloxazine A selective norepinephrine reuptake inhibitor indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults in children. Vinblastine A vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. Vinorelbine A vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC. Vismodegib A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. Vitis vinifera seed Not Annotated Voclosporin A calcineurin inhibitor for the treatment of lupus nephritis (LN) in patients diagnosed with systemic lupus erythematosus (SLE). Vonoprazan A potassium-competitive acid blocker used in the treatment of acid-related disorders and as an adjunct to Helicobacter pylori eradication. Voriconazole A triazole compound used to treat fungal infections. Warfarin A vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction. WIN 55212-2 WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It... Xanomeline A muscarinic agonist used in conjunction with trospium, a muscarinic antagonist, to treat schizophrenia. Zafirlukast A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. Zileuton A leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma. Zimelidine For the treatment of depression. Ziprasidone An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia. Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. - Drugs & Drug Targets