Recurrent Gliomas (DBCOND0054243)

Identifiers

Synonyms

Recurrent Glioma

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06397560	PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial	No drug interventions	treatment	Not Available	not_yet_recruiting
NCT06630338	Use of Shear Wave Elastography for Intraoperative Brain and Glioma Stiffness Measurements	No drug interventions	Not Available	Not Available	not_yet_recruiting
NCT02465060	Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)	ABSK-091 Adavosertib Afatinib Binimetinib Capivasertib Copanlisib Crizotinib Dabrafenib Dasatinib Defactinib Erdafitinib GSK-2636771 Ipatasertib Larotrectinib Methane Nivolumab Osimertinib Palbociclib Pertuzumab Relatlimab Sapanisertib Sulfate ion Sunitinib Taselisib Trametinib Trastuzumab Trastuzumab emtansine Tyrosine Ulixertinib Vismodegib	screening	2	active_not_recruiting
NCT03213678	Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)	LY-3023414	treatment	2	active_not_recruiting
NCT03213704	Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)	Larotrectinib Sulfate ion	treatment	2	active_not_recruiting
NCT03155620	Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)	Ensartinib Erdafitinib Hydrogen LY-3023414 Larotrectinib Menthol Olaparib Palbociclib Selpercatinib Selumetinib Sulfate ion Tazemetostat Tipifarnib Ulixertinib Vemurafenib X-396	screening	2	recruiting
NCT03526250	Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)	Palbociclib	treatment	2	active_not_recruiting
NCT03698994	Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)	Ulixertinib	treatment	2	active_not_recruiting
NCT05045027	Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma	No drug interventions	basic_science	0	recruiting
NCT04740190	Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd	Carboplatin Talazoparib	treatment	2	unknown_status
NCT05297864	PARP Inhibition for Gliomas (PI-4G or π4g)	Niraparib	treatment	2	terminated
NCT05611645	Low-dose Bevacizumab With HSRT vs BVZ Alone for GBM at First Recurrence	Bevacizumab	treatment	2	active_not_recruiting
NCT05406700	Niraparib In Recurrent IDH 1/2 Gliomas	Niraparib	treatment	0	recruiting
NCT04089449	A Study of PRT811 in Participants With Advanced Solid Tumors, CNS Lymphoma and Gliomas	No drug interventions	treatment	1	completed
NCT03389230	Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma	No drug interventions	treatment	1	active_not_recruiting
NCT03213665	Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)	Tazemetostat	treatment	2	active_not_recruiting
NCT03796273	Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases	Ketoconazole	treatment	0	terminated
NCT04164901	Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO)	Vorasidenib	treatment	3	active_not_recruiting
NCT04216550	Prediction of Therapeutic Response of Apatinib in Recurrent Gliomas	Rivoceranib	Not Available	Not Available	recruiting
NCT04562077	Role of Surgery in Treatment of Recurrent Brian Glioma:Prognostic Factors and Outcome	No drug interventions	Not Available	Not Available	unknown_status
NCT04943718	Personalized Vaccine for Patients With Recurrent Malignant Glioma	No drug interventions	treatment	1	unknown_status
NCT01324635	Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors	Panobinostat	treatment	1	terminated
NCT03212274	Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations	Olaparib	treatment	2	active_not_recruiting
NCT05676489	MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors	No drug interventions	diagnostic	0	not_yet_recruiting
NCT03233204	Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)	Olaparib	treatment	2	completed
NCT04794972	A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors	No drug interventions	treatment	1	recruiting
NCT05660369	CARv3-TEAM-E T Cells in Glioblastoma	No drug interventions	treatment	1	recruiting
NCT01580969	Repeat Radiation, Minocycline and Bevacizumab in Patients With Recurrent Glioma	Bevacizumab Minocycline	treatment	1 / 2	completed
NCT03411408	Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.	No drug interventions	treatment	Not Available	recruiting
NCT01445119	A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent Gliomas	Carboplatin Enzastaurin	treatment	1	completed