Malignant Glioma (DBCOND0029627)

Identifiers

Synonyms
Milignant Gliomas / Gliomas, Malignant / Glioma, Malignant / Malignant Gliomas / Malignant glioma / Glial tumours malignant / Glioma, malignant (morphologic abnormality)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02494804
Effect of Cytokine-induced Killer Cells for Stage I-II Malignant GliomasNot Available1 / 2not_yet_recruiting
NCT06640582
TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and MeningiomasNo drug interventionstreatment1 / 2not_yet_recruiting
NCT06270082
Study of IK-595 in RAS- or RAF-altered Advanced TumorsNo drug interventionstreatment1recruiting
NCT06562621
Clinical Study on the Safety and Efficacy of Novel Oncolytic Virus in the Treatment of Recurrent Malignant Gliomatreatment1 / 2completed
NCT04327011
A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511treatment1terminated
NCT05475522
Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain MetastasesNo drug interventionstreatmentNot Availablerecruiting
NCT06397560
PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies TrialNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05553041
18F-Fluciclovine PET-MRI in High-grade Gliomadiagnostic0recruiting
NCT06636162
Window of Opportunity Study of DSP-0390 in GliomasNo drug interventionstreatment0not_yet_recruiting
NCT05271240
Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBMtreatment3recruiting
NCT05500508
Oral AMXT 1501 Dicaprate in Combination with IV DFMOtreatment1 / 2active_not_recruiting
NCT05954858
Surgical Tissue Flap to Bypass the Blood Brain Barrier in GlioblastomaNo drug interventionstreatmentNot Availablerecruiting
NCT05979064
Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)No drug interventionstreatmentNot Availablerecruiting
NCT04091503
Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastomatreatment1completed
NCT04998864
Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05100602
Clinical Evaluation of Genetron TERT PCR Kit in Glioma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04741984
Monocyte Antigen Carrier Cells for Newly Diagnosed GBMtreatment1withdrawn
NCT05656053
Intraoperative Rapid Diagnosis of Glioma Based on Fusion of Magnetic Resonance and Ultrasound ImagingNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04547777
Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Gliomatreatment1recruiting
NCT03392545
Combination of Immunization and Radiotherapy for Malignant Gliomas (InSituVac1)No drug interventionstreatment1unknown_status
NCT05283109
ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBMtreatment1recruiting
NCT05406700
Niraparib In Recurrent IDH 1/2 Gliomastreatment0recruiting
NCT04497142
Effect of Perampanel on Peritumoral Hyperexcitability in HGGtreatment1 / 2completed
NCT05896449
Predictive Values of Preoperative [68Ga]Ga-PSMA-11 PET/CT in Patients With Suspected Brain Tumours of Glial OriginNo drug interventionsdiagnosticNot Availablecompleted
NCT06499636
In Vitro Models From Pediatric Brain TumorsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06258018
Niraparib and Temozolomide in Patients Glioblastomatreatment1 / 2not_yet_recruiting
NCT06196918
Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma PatientspreventionNot Availablerecruiting
NCT05772741
Grafts of GSCs Into Brain Organoids for Testing Anti-invasion DrugsNo drug interventionsbasic_scienceNot Availablerecruiting
NCT06203496
Monitoring of Patients With Diffuse Gliomas Using Circulating miRNAsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05393258
Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant GliomasNo drug interventionstreatmentNot Availablerecruiting
NCT05556486
Mapping of Tumor Stem Cells in the Resection Marigin During Extirpation of Highly Malignant Gliomas Using GlioStemNo drug interventionsNot AvailableNot Availablerecruiting
NCT04541225
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid TumorsNo drug interventionstreatment1terminated
NCT03416530
ONC201 in Pediatric H3 K27M Gliomastreatment1active_not_recruiting
NCT06381726
Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of LifeNo drug interventionstreatmentNot Availablerecruiting
NCT05263466
Establishing Radiolabelled PSMA as a Target for Glioma TreatmentNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT05063682
The Efficacy and Safety of Brain-targeting Immune Cells (EGFRvIII-CAR T Cells) in Treating Patients With Leptomeningeal Disease From Glioblastoma. Administering Patients EGFRvIII -CAR T Cells May Help to Recognize and Destroy Brain Tumor Cells in PatientsNo drug interventionstreatment1unknown_status
NCT06499831
18F-FET-PET/MRI vs Standard MRI Alone for Stereotactic RadioTherapy Planning for High Grade Brain GliomasNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT05474573
Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and MetastasesNo drug interventionstreatmentNot Availablerecruiting
NCT06585527
Clinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant GliomaNo drug interventionstreatment1recruiting
NCT05695976
GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBMNo drug interventionsNot AvailableNot Availablerecruiting
NCT05366062
ERC1671 to Treat Malignant Gliomas When Given in Combination With GM-CSF, Cyclophosphamide, Bevacizumab and Pembrolizumabtreatment2not_yet_recruiting
NCT03434262
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumorstreatment1completed
NCT05557240
Neoantigens Phase I Trial in Newly Diagnosed Glioblastoma PatientstreatmentNot Availablerecruiting
NCT05873946
Assessing the Effectiveness of 2D Non-Navigated Intraoperative Ultrasound in Glioma SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT04608812
Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resectiontreatment1terminated
NCT03576612
GMCI, Nivolumab, and Radiation Therapy in Treating Patients With Newly Diagnosed High-Grade Gliomastreatment1active_not_recruiting
NCT05485038
General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor AreasNo drug interventionstreatmentNot Availablerecruiting
NCT04547621
HSRT and IMRT Chemoradiotherapy for Newly Diagnosed GBMtreatment1 / 2unknown_status
NCT04895553
Incidence of Intracranial Hemorrhage in Glioma Patients With Venous Thromboembolism Converted From LMWH to ApixabanNo drug interventionsNot AvailableNot Availableterminated
NCT04562077
Role of Surgery in Treatment of Recurrent Brian Glioma:Prognostic Factors and OutcomeNo drug interventionsNot AvailableNot Availableunknown_status
NCT05850377
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade GliomasNot AvailableNot Availablenot_yet_recruiting
NCT05182905
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma PatientsNo drug interventionstreatment0recruiting
NCT04222309
Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)No drug interventionstreatment1suspended
NCT05267509
An Integrated Radio-immunological ApproachNo drug interventionsNot AvailableNot Availablerecruiting
NCT05076513
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Gliomatreatment0recruiting
NCT05806619
Glioma: Biomolecular AspectsNo drug interventionsNot AvailableNot Availablecompleted
NCT04904419
Multi-center Research Project for Glioma Molecular Pathology Intraoperative Rapid DetectionNo drug interventionsNot AvailableNot Availablecompleted
NCT05773326
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGGtreatment0recruiting
NCT05100173
Clinical Evaluation of Genetron IDH1 PCR Kit in Glioma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04924127
Molecular Pathology Research Project of GliomaNo drug interventionsNot AvailableNot Availablecompleted
NCT06468176
Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse GliomaNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT05764460
Social Cognition and Language in Patients With GliomasNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06038760
Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO)No drug interventionsNot AvailableNot Availablerecruiting
NCT05226494
Safety and Tolerability of Fb-PMT in Recurrent Glioblastomatreatment1recruiting
NCT05969691
Radiomics-Based Visualization and Quantitative Validation of IDH1 Heterogeneity in GliomasNo drug interventionsotherNot Availableactive_not_recruiting
NCT06169280
Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade GliomaNo drug interventionstreatment1not_yet_recruiting
NCT05772767
Modulation of Ciliogenesis in Glioma Stem CellsNo drug interventionsbasic_scienceNot Availablerecruiting
NCT05356312
Glioblastoma and Individualized TherapiesNo drug interventionsNot AvailableNot Availableavailable
NCT06172595
FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade GliomaNo drug interventionsdiagnostic2not_yet_recruiting
NCT05555550
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGGdiagnostic0not_yet_recruiting
NCT06323408
Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and GliomasNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01670890
Efficacy and Safety of TMZ Plus CDDP in the Patients With Recurrent Malignant Gliomastreatment2unknown_status
NCT02731521
Clinical Development of MR Spectroscopy and Imaging in Brain CancersNo drug interventionsNot AvailableNot Availablecompleted
NCT00822887
Dose Escalation Study of Vandetanib With Hypofractionated Stereotactic Radiotherapy in Recurrent Malignant Gliomastreatment1completed
NCT00590954
Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomastreatment2completed
NCT00165477
Study of Lenalidomide and XRT in Patients With Newly Diagnosed Glioblastoma Multiformetreatment2completed
NCT00271609
Bevacizumab for Recurrent Malignant Gliomatreatment2completed
NCT02388659
Clinical Development of Cancer-Specific MRS Biomarkers in Malignant GliomasNo drug interventionsNot AvailableNot Availablecompleted
NCT00923117
Sunitinib to Treat Recurrent Brain Cancertreatment2terminated
NCT01657734
Multimodal MR Imaging in Patients With Glioblastoma Treated With Dendritic Cell TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT00704080
A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomastreatment1completed
NCT01549392
Imaging Study of Glioblastomas Treated With AvastinNo drug interventionsdiagnosticNot Availableterminated
NCT00074646
Phase I Trial of CC-8490 for the Treatment of Subjects With Recurrent/Refractory High-Grade Gliomastreatment1completed
NCT00879437
Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Gliomatreatment2completed
NCT02155452
Fluorescence and Glioma HeterogeneityNo drug interventionsNot AvailableNot Availablecompleted
NCT02632370
5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant TumorNot AvailableNot Availablecompleted
NCT03212742
Phase I/IIa Study of Concomitant Radiotherapy With Olaparib and Temozolomide in Unresectable High Grade Gliomas Patientstreatment1 / 2recruiting
NCT00463073
Cetuximab, Bevacizumab and Irinotecan for Patients With Malignant GlioblastomasNot Available2completed
NCT00671801
Irinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma Multiforme: Phase Itreatment1terminated
NCT00272350
ZD6474 to Treat Advanced Brain Cancer in Patientstreatment1completed
NCT02369367
Irinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma Multiforme (Phase II)treatment2withdrawn
NCT02359565
Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastomatreatment1recruiting
NCT02465268
Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiformetreatment2completed
NCT03213678
Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)treatment2active_not_recruiting
NCT03919071
Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Gliomatreatment2recruiting
NCT05099003
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)treatment1 / 2recruiting
NCT03155620
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)screening2recruiting
NCT03581292
Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutationstreatment2active_not_recruiting
NCT03718767
Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotypetreatment2recruiting
NCT03952598
Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR SpectroscopyNo drug interventionsdiagnosticNot Availablerecruiting
NCT04817254
Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcomatreatment2recruiting
NCT05045027
Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent GliomaNo drug interventionsbasic_science0recruiting
NCT04771806
Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade GliomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05030298
Preoperative Radiosurgery for the Treatment of High Grade Glioma, the NeoGlioma Studytreatment1 / 2recruiting
NCT05773664
Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients with Glioblastomatreatment1withdrawn
NCT06470711
Mapping of Electrical Properties in the BrainNo drug interventionsNot AvailableNot Availablerecruiting
NCT03893903
AMPLIFYing NEOepitope-specific VACcine Responses in Progressive Diffuse Gliomatreatment1active_not_recruiting
NCT00032903
This is an Early Study to Investigate the Effect of Gimatecan® in Adults With Malignant Glioma.treatment1 / 2completed
NCT00953121
Bevacizumab Plus Irinotecan Plus Carboplatin for Recurrent Malignant Glioma (MG)treatment2completed
NCT00528684
Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomastreatment1completed
NCT02549833
Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Gliomatreatment1active_not_recruiting
NCT01817751
Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Gliomatreatment2completed
NCT00087451
Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)treatment1completed
NCT05717153
Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Gliomabasic_science0recruiting
NCT01891747
A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Gliomatreatment1completed
NCT05486247
Molecular Characterization of Gliomas Using a Broad Next Generation Sequencing (NGS)PanelNo drug interventionsNot AvailableNot Availablecompleted
NCT01235845
Dendritic Cell (DC) Activated Cytokine-induced Killer Cell (DCIK) Combined With DC Treatment for GliomaNo drug interventionstreatment1 / 2unknown_status
NCT02457845
HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumorstreatment1completed
NCT03735498
Psychological Intervention for Caregivers of Patients With Malignant GliomasNo drug interventionssupportive_careNot Availablecompleted
NCT00717197
Study of Capecitabine to Treat Recurrent High Grade Gliomastreatment2completed
NCT05293197
Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric PatientsNo drug interventionstreatment1recruiting
NCT02794883
Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Gliomatreatment2completed
NCT02540161
Phase 2 Study of Sym004 for Adult Patients With Recurrent Glioblastomatreatment2completed
NCT04013828
Treatment Decision-making in Patients With Recurrent High-grade GliomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01491893
PVSRIPO for Recurrent Glioblastoma (GBM)treatment1completed
NCT02303678
D2C7 for Adult Patients With Recurrent Malignant Gliomatreatment1completed
NCT02986178
PVSRIPO in Recurrent Malignant Gliomatreatment2active_not_recruiting
NCT03684109
Non-invasive Glioma Characterization Through Molecular ImagingNo drug interventionsdiagnosticNot Availablerecruiting
NCT01515085
MRI-Guided Laser Induced Thermal TherapyNo drug interventionsNot AvailableNot Availableterminated
NCT00919737
Study of NPC-08 is to Treat for Newly-Diagnosed Malignant Glioma and Recurrent Glioblastoma MultiformeNo drug interventionstreatment1 / 2completed
NCT02300532
Post-Marketing Surveillance of Gliadel 7.7mg Implant (All-case Observational Study)No drug interventionsNot AvailableNot Availablecompleted
NCT00589875
Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Gliomatreatment2completed
NCT00751270
Phase 1b Study of AdV-tk + Valacyclovir Combined With Radiation Therapy for Malignant Gliomastreatment1completed
NCT02300506
Post-Marketing Surveillance of Long-Term Observation of Gliadel Wafer-Investigation of Vital Prognosis in Patients With High Grade GliomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01868906
FMISO-PET in Brain Tumors and SCS Effectdiagnostic2terminated
NCT00735436
A Study of Gliadel Followed by Avastin + Irinotecan for Glioblastoma Multiforme (GBM)treatment2terminated
NCT04937413
The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluationbasic_science0completed
NCT01351519
A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumorstreatment2terminated
NCT02375334
Adherence Monitoring System in Managing Myelosuppression in Patients With Newly Diagnosed Malignant Gliomas Receiving Temozolomide and Radiation TherapyNo drug interventionsNot AvailableNot Availableterminated
NCT01454596
CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIIItreatment1 / 2completed
NCT00591058
Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Gliomatreatment1unknown_status
NCT01400958
Nuvigil or Placebo in Newly Diagnosed Malignant Gliomasupportive_care2terminated
NCT02047058
Treatment Response and Prognosis in Glioma Patients: Q Cell and Its Biological CharacteristicsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02590263
Study Evaluating ABT-414 in Japanese Subjects With Malignant Gliomatreatment1 / 2completed
NCT02855086
Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgerydiagnostic1 / 2terminated
NCT00859222
LBH589 and Bevacizumab in Patients With Recurrent High Grade Gliomatreatment1 / 2completed
NCT01167322
Study of NPC-07 for Fluorescence-guided Resection of Malignant Gliomasdiagnostic3completed
NCT02861222
Myocet® in Children With Relapsed or Refractory Non-brainstem Malignant Gliomatreatment1completed
NCT03389230
Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV GliomaNo drug interventionstreatment1active_not_recruiting
NCT00024557
Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patientstreatment1completed
NCT02371031
FDOPA-PET/MRI for the Pre-operative Evaluation of GliomasNo drug interventionsdiagnostic1terminated
NCT02025231
Image Guided Reirradiation of High-grade GliomaNo drug interventionstreatment1 / 2terminated
NCT03778294
18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapytreatment2completed
NCT02644291
Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumorstreatment1completed
NCT01386580
An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.treatment1 / 2completed
NCT03033992
Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPGNo drug interventionstreatmentNot Availablerecruiting
NCT01811992
Combined Cytotoxic and Immune-Stimulatory Therapy for GliomaNo drug interventionstreatment1completed
NCT04197492
Hypofractionated Stereotactic Radiotherapy With Anlotinib in Patients With Recurrent High-Grade Gliomastreatment2active_not_recruiting
NCT00458601
Phase II Study of Rindopepimut (CDX-110) in Patients With Glioblastoma Multiformetreatment2completed
NCT04175301
Effect H2 Water on QoL of Patients Receiving Radiotherapy for High Grade Gliomas.treatment2active_not_recruiting
NCT03615404
Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastomatreatment1completed
NCT02903069
Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancertreatment1completed
NCT02391246
Radionecrosis and FDG PETNo drug interventionsNot AvailableNot Availableunknown_status
NCT01738646
Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patientstreatment2completed
NCT04521946
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancertreatment1withdrawn
NCT02104310
A Pilot Study Using 18F-DOPA PET-guided Radiotherapy in GliomasNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03244995
Mind-Body Intervention in Glioma CouplesNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT01017250
Radiosurgery and Avastin for Recurrent Malignant GliomastreatmentNot Availablecompleted
NCT00190723
A Study of LY317615 in Patients With Brain Tumorstreatment2completed
NCT03510208
Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgerydiagnostic1 / 2recruiting
NCT02892708
Impact of Surgery on the Treatment of Supratentorial Malignant Gliomas in Subjects Aged 70 and OverNo drug interventionstreatment3completed
NCT00157703
G207 Followed by Radiation Therapy in Malignant GliomaNo drug interventionstreatment1completed
NCT00064779
Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Gliomatreatment1completed
NCT04630379
Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their CaregiversNo drug interventionssupportive_careNot Availablecompleted
NCT03973879
Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Gliomatreatment1 / 2withdrawn
NCT03749187
BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomastreatment1recruiting
NCT00041587
Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Gliomatreatment1 / 2completed
NCT00075387
Combination Chemotherapy With or Without Sodium Thiosulfate in Preventing Low Platelet Count While Treating Patients With Malignant Brain Tumorstreatment2unknown_status
NCT02764151
First in Patient Study for PF-06840003 in Malignant GliomasNo drug interventionstreatment1terminated
NCT00766753
Vaccination-Dendritic Cells With Peptides for Recurrent Malignant GliomasNo drug interventionstreatment1 / 2completed
NCT01991977
18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapydiagnostic2active_not_recruiting
NCT01249105
MK-2206 for Recurrent Malignant Gliomatreatment2withdrawn
NCT03334305
Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomastreatment1active_not_recruiting
NCT01792505
Dendritic Cell Vaccine With Imiquimod for Patients With Malignant Gliomatreatment1completed
NCT00125697
Characterization of Serial Magnetic Resonance Spectroscopy Imaging in Patients With Malignant Glioma Undergoing RadiotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT03678883
9-ING-41 in Patients With Advanced Cancerstreatment2active_not_recruiting
NCT02507583
Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant GliomaNo drug interventionstreatment1completed
NCT00683761
A Study of 131I-TM601 in Adults With Recurrent Malignant GliomaNo drug interventionstreatment1 / 2unknown_status
NCT01432171
Lacosamide in Preventing Seizures in Participants With Malignant GliomapreventionNot Availableterminated
NCT02663271
TTFields and Pulsed Bevacizumab for Recurrent Glioblastomatreatment2terminated
NCT02039778
Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade GliomaNo drug interventionstreatmentNot Availableterminated
NCT01392209
Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant GliomaNo drug interventionstreatment1completed
NCT00114309
131-I-TM-601 Study in Adults With Recurrent High-Grade Gliomatreatment2unknown_status
NCT01316809
AZD8055 for Adults With Recurrent Gliomastreatment1completed
NCT04109209
Psychological Intervention For Brain Tumor CaregiversNo drug interventionssupportive_careNot Availablecompleted
NCT03299309
PEP-CMV in Recurrent MEdulloblastoma/Malignant GliomaNo drug interventionstreatment1active_not_recruiting
NCT00782756
Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant GliomaNo drug interventionstreatment2completed
NCT00283556
High Dose Camptothecin-11 (CPT-11) in Recurrent Unresectable Malignant Gliomatreatment1 / 2completed
NCT02659800
Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomassupportive_care1terminated
NCT00024570
Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Gliomatreatment1 / 2completed
NCT03956706
Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant GliomasNo drug interventionstreatmentNot Availablewithdrawn
NCT04943718
Personalized Vaccine for Patients With Recurrent Malignant GliomaNo drug interventionstreatment1unknown_status
NCT02526017
Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancerstreatment1completed
NCT03501134
Quality of Life of Patients With Glioblastoma (GBM) Treated With Tumor-Treating FieldsNo drug interventionsNot AvailableNot Availablecompleted
NCT01740258
Bevacizumab Beyond Progression (BBP)treatment2completed
NCT03220035
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)treatment2active_not_recruiting
NCT01303835
Low Dose Naltrexone for Glioma Patientstreatment2completed
NCT01952886
Patient Satisfaction, Efficacy and Compliance of Antiemetic Patch vs Pill in Malignant Glioma Patientssupportive_care2withdrawn
NCT00900757
Intravenous Palonosetron With Radiotherapy and Concomitant Temozolomideprevention2completed
NCT01004874
Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastomatreatment2completed
NCT01808820
Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastomatreatment1completed
NCT03387020
Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumorstreatment1completed
NCT02020720
18F-DOPA-PET in Planning Surgery in Patients With GliomasNo drug interventionsdiagnostic0active_not_recruiting
NCT02661282
Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastomatreatment1 / 2completed
NCT02311582
MK-3475 in Combination With MRI-guided Laser Ablation in Recurrent Malignant Gliomastreatment1 / 2completed
NCT01266031
Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastomatreatment1 / 2completed
NCT00634231
A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumorstreatment1completed
NCT02829931
Hypofractionated Stereotactic Irradiation With Nivolumab, Ipilimumab and Bevacizumab in Patients With Recurrent High Grade Gliomastreatment1completed
NCT04160494
D2C7-IT With Atezolizumab for Recurrent Gliomastreatment1active_not_recruiting
NCT03043391
Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Childrentreatment1completed
NCT02330562
Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumabtreatment1 / 2completed
NCT02186262
Rotating Frame Relaxation and Diffusion Weighted Imaging of Human GliomasNo drug interventionsNot AvailableNot Availablecompleted
NCT03746080
Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastomatreatment2active_not_recruiting
NCT02323880
Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomastreatment1active_not_recruiting
NCT02315989
Early-Phase Safety of Proton Therapy EquipmentNo drug interventionstreatmentNot Availablecompleted
NCT00766467
A Randomized Placebo-Controlled Trial of Armodafinil (Nuvigil) for Fatigue in Patients With Malignant Gliomassupportive_care2completed
NCT04650204
Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsyprevention4terminated
NCT03233204
Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)treatment2completed
NCT02529072
Nivolumab With DC Vaccines for Recurrent Brain Tumorstreatment1completed
NCT02313272
Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomastreatment1completed
NCT05660369
CARv3-TEAM-E T Cells in GlioblastomaNo drug interventionstreatment1recruiting
NCT03471546
Early Palliative Care Intervention in Malignant GliomaNo drug interventionssupportive_careNot Availablecompleted
NCT00576446
Surgical Resection With Gliadel Wafer Followed by Dendritic Cells Vaccination for Malignant Glioma PatientsNo drug interventionstreatment1completed
NCT04323046
Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adultstreatment1recruiting
NCT02023346
Prognostic Awareness and Patient-Physician Communication in Malignant GliomaNo drug interventionsNot AvailableNot Availablecompleted
NCT03915912
Mindfulness Meditation in Glioma PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT00125710
Comparative 2-D Tumor Analysis in Familial GliomasNo drug interventionsNot AvailableNot Availablecompleted
NCT02278510
Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Gliomatreatment0completed
NCT04903795
Bispecific T Cell Engager BRiTE for Patients With Grade IV Malignant GliomaNo drug interventionstreatment1not_yet_recruiting
NCT03411408
Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.No drug interventionstreatmentNot Availablerecruiting
NCT00103038
Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral MetastasesdiagnosticNot Availablecompleted
NCT02924038
A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)treatment1terminated