Emixustat

DB12608InvestigationalSmall molecule

Emixustat has been used in trials studying the treatment of Geographic Atrophy, Age-Related Macular Degeneration, and Dry Age-related Macular Degeneration.

Mechanism: Pharmacologically active on Retinoid isomerohydrolase
Curator reviewed
Formula / weight: C₁₆H₂₅NO₂ · 263.381 g/mol (avg)
Code names: ACU-4429

Resolves to

Compound

UNII02DZ1HBF0MCAS1141777-14-1ChEMBLCHEMBL2107821PubChem25221720

Structure

InChIKeyWJIGGYYSZBWCGC-MRXNPFEDSA-NSMILESNCC[C@@H](O)C1=CC(OCC2CCCCC2)=CC=C1

Targets

Q16518RPE65

What you can answer from here — as of September 19, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

7Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Emixustat, and which of those have an active Phase 3 trial?

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