- Anesthetics, Local
- Accession Number
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
- ATC Classification
Drug Drug Description Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Ropivacaine An amide-type local anesthetic used for local or regional anesthesia during surgery and for short-term management of acute pain. Bupivacaine A local anesthetic used in a wide variety of superficial and invasive procedures. Dyclonine An topical anesthetic used prior to examination to suppress the gag reflex or for pain relief from canker sores and fever blisters. Procaine A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block. Prilocaine A local anesthetic used in dental procedures. Proparacaine A topical anesthetic used for ophthalmic practice. Mepivacaine A local anesthetic used for local or regional analgesia or anesthesia. Levobupivacaine A drug used for nerve block and anesthesia. Benzocaine A topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations. Chloroprocaine A local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, spinal anesthesia, or ocular surface anesthesia. Etidocaine Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage... Articaine A local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures. Tetracaine A local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures. Ethyl chloride A local anesthetic. Oxybuprocaine A local anesthetic used in ophthalmology. Phenol An antiseptic and disinfectant used in a variety of settings. Cinchocaine An anesthetic used for local or regional anesthesia. Cocaine An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. Diphenhydramine A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. Tetrodotoxin For the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence. Benzyl alcohol An antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older. Propoxycaine Propoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures . It has been combined with procaine to accelerate its onset of action and... Pramocaine A local anesthetic and antipruritic agent found in various topical preparations. Butamben Anesthesia of mucus membranes other than the eyes. Butacaine Not Annotated Quinisocaine Not Annotated Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Oxetacaine An antacid used to treat gastritis, peptic ulcer disease, heartburn, esophagitis, hiatus hernia, and anorexia. Butanilicaine Not Annotated Metabutethamine Not Annotated Meloxicam An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics.
- Drugs & Drug Targets