Anesthetics
- Name
- Anesthetics
- Accession Number
- DBCAT000564 (DBCAT003828)
- Description
Agents that are capable of inducing a total or partial loss of sensation, especially tactile sensation and pain. They may act to induce general ANESTHESIA, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site.
- ATC Classification
- Drugs
Drug Drug Description Alfaxalone Alfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use... Alfentanil An opioid agonist used to induce and maintain anesthesia, as well as an analgesic. Ambroxol A medication indicated for airway secretion clearance therapy. Anileridine An opioid analgesic used to treat moderate to severe pain. Articaine A local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures. Benzocaine A topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations. Benzyl alcohol An antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older. Brexanolone Brexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label] . Bupivacaine A local anesthetic used in a wide variety of superficial and invasive procedures. Butacaine Not Annotated Butamben Anesthesia of mucus membranes other than the eyes. Butanilicaine Not Annotated Canertinib Investigated for use/treatment in breast cancer and lung cancer. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Chloralose Chloralose is a small molecule drug. Chloralose has a monoisotopic molecular weight of 307.96 Da. Chloroform Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on... Chloroprocaine A local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, spinal anesthesia, or ocular surface anesthesia. Cinchocaine An anesthetic used for local or regional anesthesia. Cipepofol An alkylphenol GABA-A positive allosteric modulator used for induction of general anesthesia in adults undergoing surgery. Clonidine An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. Cocaine An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. Cyclopropane Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene. Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery... Desflurane A general inhalation anesthetic for inpatient and outpatient surgery in adults. Dexmedetomidine An alpha-2 agonist used for sedation during various procedures. Diazepam A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. Diethyl ether Not Annotated Diphenhydramine A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. Dyclonine An topical anesthetic used prior to examination to suppress the gag reflex or for pain relief from canker sores and fever blisters. Eltanolone Eltanolone is under investigation in clinical trial NCT02603926 (Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone). Enflurane A halogenated inhalational anesthetic agent used for the induction and maintenance of anesthesia and for analgesia during labor and delivery. Enibomal Not Annotated Esketamine A NMDA receptor antagonist used for treatment-resistant depression. Ethyl chloride A local anesthetic. Etidocaine Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage... Etomidate A short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures. Fentanyl An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. Fospropofol A sedative-hypnotic agent indicated for monitored anesthesia care (MAC) sedation in adult patients undergoing diagnostic or therapeutic procedures. Gaboxadol Investigated for use/treatment in sleep disorders and insomnia. gamma-Hydroxybutyric acid Gamma-hydroxybutyric acid is a central nervous system depressant indicated for the treatment of cataplexy or excessive daytime sleepiness (EDS) in patients aged 7 years and older with narcolepsy, as well... Halothane A general inhalation anesthetic used for the induction and maintenance of general anesthesia. Hexobarbital For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful... Isoflurane An inhaled general anesthetic used in surgery. Ketamine A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant. Levobupivacaine A drug used for nerve block and anesthesia. Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Meloxicam An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. Mepivacaine A local anesthetic used for local or regional analgesia or anesthesia. Metabutethamine Not Annotated Methohexital An anesthetic used to induce deep sedation. Methoxyflurane For use in the induction and maintenance of general anesthesia Midazolam A short-acting benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. Minaxolone Minaxolone is a small molecule drug. Minaxolone has a monoisotopic molecular weight of 405.32 Da. Morphine An opioid agonist used for the relief of moderate to severe acute and chronic pain. Nitrous oxide An inhalatory gas used as an adjunct to improve oxygenation and reduce the need for extracorporeal membrane oxygenation in certain neonates with hypoxic respiratory failure. Norflurane Norflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage). Oliceridine A biased opioid agonist indicated for the management of severe acute pain in adult patients. Through preferential activation of G-protein-coupled signalling pathways, oliceridine provides analgesic effect with a comparable or improved safety profile over conventional opioid agonists. Oxethazaine An antacid used to treat gastritis, peptic ulcer disease, heartburn, esophagitis, hiatus hernia, and anorexia. Oxybuprocaine A local anesthetic used in ophthalmology. Phenol An antiseptic and disinfectant used in a variety of settings. Phenoperidine Not Annotated Phenoxyethanol An antiseptic used as a hand disinfectant or preservative in medications. Pramocaine A local anesthetic and antipruritic agent found in various topical preparations. Prilocaine A local anesthetic used in dental procedures. Procaine A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block. Propanidid An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918) Proparacaine A topical anesthetic used for ophthalmic practice. Propofol A medication used in general anesthesia and for sedation. Propofol Hemisuccinate Not Annotated Propoxycaine Propoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures . It has been combined with procaine to accelerate its onset of action and... Quinisocaine Not Annotated Remifentanil An opioid analgesic used in anesthesia. Romifidine Romifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species.... Ropivacaine An amide-type local anesthetic used for local or regional anesthesia during surgery and for short-term management of acute pain. Sepranolone Sepranolone has been investigated for the treatment of Premenstrual Dysphoric Disorder. Sevoflurane A inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures. Sodium oxybate A central nervous system depressant used to treat cataplexy and excessive daytime sleepiness (EDS) associated with narcolepsy. Sufentanil An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain. Tetracaine A local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures. Tetrodotoxin For the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence. Thiamylal Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state. Thiopental A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. Tiletamine This drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt... Tricaine Tricaine (as tricaine methanesulfonate) is white powder used for anesthesia, sedation, or euthanasia of fish. It is also the only anesthetic licensed in the United States for use in fin... Trichloroethylene Trichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. It has been sold under a variety of... Urethane Urethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963. Vinyl ether Not Annotated Xenon Not Annotated