HER2 negative (DBCOND0024919)

Identifiers

Synonyms
HER2/Neu Negative / HER2-negative / Human epidermal growth factor receptor negative

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03872388
Atorvastatin in Treating Patients With Stage IIb-III Triple Negative Breast Cancer Who Did Not Achieve a Pathologic Complete Response After Receiving Neoadjuvant Chemotherapytreatment2terminated
NCT03070002
Denosumab in Treating Patients With ER and/or PR Positive, HER2 Negative Metastatic Breast Cancer With Bone Metastases and Detectable Circulating Tumor Cellstreatment2terminated
NCT02945579
Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic TherapyNo drug interventionstreatmentNot Availablerecruiting
NCT01238133
Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097, Paclitaxel, and Carboplatin Before Surgery in Treating Patients With Stage II or Stage III Triple-Negative Breast Cancertreatment1terminated
NCT03359954
Radiation Therapy Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Breast CancerNo drug interventionstreatment2active_not_recruiting
NCT03599453
Chemokine Modulation Therapy and Pembrolizumab in Treating Participants With Metastatic Triple-Negative Breast Cancertreatment0completed
NCT02744053
DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancerdiagnostic0active_not_recruiting
NCT02648477
Pembrolizumab and Doxorubicin Hydrochloride or Anti-Estrogen Therapy in Treating Patients With Triple-Negative or Hormone Receptor-Positive Metastatic Breast Cancertreatment2completed
NCT02401347
Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumorstreatment2completed
NCT02282345
Talazoparib Before Standard Therapy in Treating Patients With Invasive, BRCA-Mutated Breast Cancertreatment2completed
NCT02971761
Pembrolizumab and Enobosarm in Treating Patients With Androgen Receptor Positive Metastatic Triple Negative Breast Cancertreatment2completed
NCT03723928
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast CancerNo drug interventionshealth_services_researchNot Availablerecruiting
NCT02876107
Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancertreatment2active_not_recruiting
NCT02411656
Pembrolizumab in Treating Patients With Stage IV Metastatic or Recurrent Inflammatory Breast Cancer or Triple-Negative Breast Cancer Who Have Achieved Clinical Response or Stable Disease to Prior Chemotherapytreatment2active_not_recruiting
NCT03566485
Atezolizumab and Cobimetinib or Idasanutlin in Participants With Stage IV or Unresectable Recurrent Estrogen Receptor Positive Breast Cancertreatment1 / 2terminated
NCT02860000
Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancertreatment2active_not_recruiting
NCT02672475
Galunisertib and Paclitaxel in Treating Patients With Metastatic Androgen Receptor Negative (AR-) Triple Negative Breast Cancertreatment1completed
NCT02208375
mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovariantreatment1 / 2active_not_recruiting
NCT03725436
ALRN-6924 and Paclitaxel in Treating Patients With Advanced, Metastatic, or Unresectable Solid Tumorstreatment1active_not_recruiting
NCT00892736
Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapytreatment1completed
NCT01754519
Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer Undergoing SurgeryNo drug interventionstreatment2terminated
NCT03128619
Copanlisib, Letrozole, and Palbociclib in Treating Patients With Hormone Receptor Positive HER2 Negative Stage I-IV Breast Cancertreatment1terminated
NCT02892734
Ipilimumab and Nivolumab in Treating Patients With Recurrent Stage IV HER2 Negative Inflammatory Breast Cancertreatment2terminated
NCT03477396
Ribociclib and Aromatase Inhibitor in Treating Older Participants With Hormone Receptor Positive Metastatic Breast Cancertreatment2completed
NCT01276496
Weekly Doses of Cilengitide and Paclitaxel in Treating Patients With Advanced Solid Tumors That Cannot Be Removed by Surgerytreatment1completed
NCT03326258
Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgerytreatment1 / 2withdrawn
NCT02432963
Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapytreatment1active_not_recruiting
NCT01928186
FLT PET in Measuring Treatment Response in Patients With Newly Diagnosed Estrogen Receptor-Positive, HER2-Negative Stage I-III Breast CancerdiagnosticNot Availablecompleted
NCT01319539
MK2206 in Treating Patients With Stage I, Stage II, or Stage III Breast CancerNo drug interventionstreatment2terminated
NCT01145430
Veliparib and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer or Metastatic Breast Cancertreatment1completed
NCT02115282
Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatictreatment3active_not_recruiting
NCT03633331
Palbociclib and Letrozole or Fulvestrant in Treating Patients With Estrogen Receptor Positive, HER2 Negative Metastatic Breast Cancertreatment2unknown_status
NCT01750073
Paclitaxel & Cyclophosphamide With or Without Trastuzumab Before Surgery in Treating Previously Untreated Breast Cancertreatment2active_not_recruiting
NCT02599194
18F-FSPG PET/CT for Cancer Patients on Therapydiagnostic2completed
NCT00785291
Paclitaxel, Nab-paclitaxel, or Ixabepilone With or Without Bevacizumab in Treating Patients With Stage IIIC or Stage IV Breast Cancertreatment3completed
NCT02445391
Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapytreatment3active_not_recruiting
NCT01846091
Viral Therapy In Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Cancer or Metastatic Breast Cancertreatment1completed
NCT03644589
Effect of Pembrolizumab and Cisplatin on Metastatic, Locally Recurrent or Inoperable Triple-Negative Breast Cancertreatment2withdrawn
NCT04090567
Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancertreatment2recruiting
NCT03132467
Durvalumab and Tremelimumab Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Stage II-III Breast Cancertreatment0completed
NCT02780401
Vaccine Therapy in Preventing Cancer Recurrence in Patients With Non-Metastatic, Node Positive, HER2 Negative Breast Cancer That is in Remissionprevention1active_not_recruiting
NCT02957968
Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Catreatment2active_not_recruiting
NCT02993068
Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)No drug interventionsdiagnosticNot Availablerecruiting
NCT02120469
Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancertreatment1completed
NCT02774681
Palbociclib in Treating Patients With Metastatic HER-2 Positive Breast Cancer With Brain Metastasistreatment2terminated
NCT03523195
Exercise Intervention After Cancer Treatment for Improving Health in Stage II-III Breast Cancer SurvivorsNo drug interventionssupportive_careNot Availablecompleted
NCT00390455
Fulvestrant With or Without Lapatinib in Treating Postmenopausal Women With Stage III or Stage IV Breast Cancer That is Hormone Receptor-Positivetreatment3completed
NCT01776008
Akt Inhibitor MK-2206 and Anastrozole With or Without Goserelin Acetate in Treating Patients With Stage II-III Breast Cancertreatment2terminated
NCT03291938
IACS-010759 in Advanced CancersNo drug interventionstreatment1completed
NCT03238703
Endocrine Therapy in Treating Patients With HER2 Negative, Low Risk Breast Cancertreatment4withdrawn
NCT03154190
Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With CancerNo drug interventionshealth_services_researchNot Availableunknown_status
NCT01071564
RO4929097 and Vismodegib in Treating Patients With Breast Cancer That is Metastatic or Cannot Be Removed By Surgerytreatment1terminated
NCT03106077
Mirvetuximab Soravtansine as First Line in Treating Patients With Triple Negative Breast Cancertreatment2completed
NCT04185311
Ipilimumab, Nivolumab, and Talimogene Laherparepvec Before Surgery in Treating Participants With Localized, Triple-Negative or Estrogen Receptor Positive, HER2 Negative Breast Cancer-deletedtreatment1terminated
NCT01697293
PTX-200, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide in Treating Patients With Stage IIB-IV Breast Cancertreatment1 / 2terminated
NCT03691493
Radiation Therapy, Palbociclib, and Hormone Therapy in Treating Breast Cancer Patients With Bone Metastasistreatment2completed
NCT01149356
RO4929097 And Exemestane in Treating Pre- and Postmenopausal Patients With Advanced or Metastatic Breast Cancertreatment1terminated
NCT00877500
Ixabepilone in Treating Participants With Significant Residual Disease of HER2/Neu Negative Invasive Breast Cancer After Systemic Therapytreatment2active_not_recruiting
NCT03715959
Nipple Aspirate Fluid in Detecting Breast CancerNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT01624441
Dinaciclib and Epirubicin Hydrochloride in Treating Patients With Metastatic Triple-Negative Breast Cancertreatment1completed
NCT03213041
Pembrolizumab and Carboplatin in Treating Patients With Circulating Tumor Cells Positive Metastatic Breast Cancertreatment2recruiting
NCT01964924
Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Metastatic Triple-Negative Breast Cancertreatment2completed
NCT02567396
Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunctiontreatment1withdrawn
NCT01575522
Tivantinib in Treating Patients With Recurrent or Metastatic Breast Cancertreatment2completed
NCT03544125
Olaparib and Durvalumab in Treating Participants With Metastatic Triple Negative Breast Cancertreatment1completed
NCT03044730
Pembrolizumab and Capecitabine in Treating Patients With Locally Advanced or Metastatic Triple Negative or Hormone-Refractory Breast Cancer That Cannot Be Removed by Surgerytreatment2unknown_status
NCT02760030
Endocrine Therapy Fulvestrant & Palbociclib or Aromatase Inhibitor Therapy in Treating Older Patients With Hormone Responsive Breast Cancer That Cannot Be Removed by Surgerytreatment2recruiting
NCT02627430
Talazoparib and HSP90 Inhibitor AT13387 in Treating Patients With Metastatic Advanced Solid Tumor or Recurrent Ovarian, Fallopian Tube, Primary Peritoneal, or Triple Negative Breast Cancertreatment1withdrawn
NCT01525966
Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Locally Advanced or Inflammatory Triple Negative Breast Cancertreatment2active_not_recruiting
NCT01251874
Veliparib and Carboplatin in Treating Patients With HER2-Negative Metastatic Breast Cancertreatment1completed
NCT02398773
FES PET/CT in Predicting Response in Patients With Newly Diagnosed Metastatic Breast Cancer Receiving Endocrine Therapydiagnostic2active_not_recruiting
NCT02536794
MEDI4736 and Tremelimumab in Treating Patients With Metastatic HER2 Negative Breast Cancertreatment2completed
NCT02037529
Eribulin Mesylate or Paclitaxel as First- or Second-Line Therapy in Treating Patients With Recurrent Stage IIIC-IV Breast Cancertreatment3suspended
NCT03207529
Alpelisib and Enzalutamide in Treating Patients With Androgen Receptor and PTEN Positive Metastatic Breast Cancertreatment1completed
NCT04081389
Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancertreatment1completed
NCT03554044
T-VEC With Chemotherapy or Endocrine Therapy in Treating Participants With HER2- Negative Breast Cancertreatment1active_not_recruiting
NCT02488967
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancertreatment3active_not_recruiting
NCT03377101
Fulvestrant and Palbociclib With or Without Copanlisib in Treating Patients With Hormone Receptor Positive, HER2 Negative, Stage IV Breast Cancertreatment2withdrawn
NCT02457910
Taselisib and Enzalutamide in Treating Patients With Androgen Receptor Positive Triple-Negative Metastatic Breast Cancertreatment1 / 2terminated
NCT01957514
Collecting, Analyzing, and Storing Samples From Patients With Metastatic, Triple Negative Breast Cancer Receiving Anti-cancer TherapyNo drug interventionsNot AvailableNot Availableterminated
NCT01281150
Veliparib in Combination With Carboplatin and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumorstreatment1completed
NCT03156309
Vaccine Therapy in Preventing Cancer Recurrence in Patients With Non-Metastatic, Node Positive, HER2 Negative Breast Cancer That is in Remissionprevention1recruiting
NCT06131424
NIS Study Determining Prevalence of HER2-low in Metastatic Breast Cancer PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT04669587
ER+/HER2- Locally Advanced or Metastatic Breast Cancer (ENZENO Study)treatment1 / 2unknown_status
NCT04757363
A Study of Nivolumab Combined With FOLFOX and Regorafenib in People Who Have HER2-Negative Esophagogastric Cancertreatment2active_not_recruiting
NCT03206203
Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancertreatment2active_not_recruiting
NCT06284746
Tirelizumab Combined With Chemotherapy in the Treatment of HER-2 Negative Locally Advanced Gastric CancerNo drug interventionstreatment2recruiting