NCT03763396
Azoles Targeting Recurrent High Grade Gliomas other 0 not_yet_recruiting NCT03779230
Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse treatment 1 / 2 completed NCT03849430
Longitudinal Analysis of the Health-related Quality of Life in Glioma Patients No drug interventions Not Available Not Available recruiting NCT03916757
V-Boost Immunotherapy in Glioblastoma Multiforme Brain Cancer No drug interventions treatment 2 unknown_status NCT03650257
A Large-scale Research for Immunotherapy of Glioblastoma With Autologous Heat Shock Protein gp96 treatment 2 unknown_status NCT03460782
An Expanded Access Program of Ipilimumab for Patients With Glioblastomas and Gliomas Not Available Not Available no_longer_available NCT03728673
A Study Utilizing Escitalopram in Glioma Patients treatment 2 recruiting NCT03698162
Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases diagnostic Not Available terminated NCT03949192
Efficacy of Kangliuwan for Recurrent Grade IV Glioma No drug interventions Not Available Not Available unknown_status NCT03102112
Noninvasively Predicting Gene Status of Glioma No drug interventions Not Available Not Available unknown_status NCT04406610
CAR-T Cell Immunotherapy for GD2 Positive Glioma Patients No drug interventions treatment 1 / 2 withdrawn NCT03496181
Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently No drug interventions Not Available Not Available active_not_recruiting NCT03534050
Neuropsychological and Oncological Outcomes in Grade 2 or 3 Glioma Patients Undergoing Postoperative Modern Radiotherapy No drug interventions treatment 2 / 3 recruiting NCT03750890
Visual Study of Molecular Genotype in Glioma Evolution No drug interventions Not Available Not Available unknown_status NCT03213002
Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM treatment 1 / 2 recruiting NCT03834740
A Phase 0 /II Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection treatment 0 completed NCT03935685
Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ treatment 2 active_not_recruiting NCT03189420
Glioma Microenvironment an Exploratory Study No drug interventions Not Available Not Available active_not_recruiting NCT03739372
Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma No drug interventions treatment Not Available active_not_recruiting NCT03194906
Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors supportive_care 2 completed NCT03927274
Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma treatment 0 terminated NCT03436433
Seizure Prophylaxis in Patients With Glioma or Brain Metastasis treatment 2 terminated NCT03698201
Blood Biomarker Signature in Glioma No drug interventions Not Available Not Available terminated NCT03665545
Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma treatment 1 / 2 active_not_recruiting NCT03796507
Early Temozolomide in Patients With High-Grade Gliomas in Rehabilitation treatment 0 withdrawn NCT03311542
Expanded Access for Pembrolizumab (MK-3475) Not Available Not Available no_longer_available NCT03180697
The Efficacy of APT Magnetic Resonance Imaging in Predicting the Efficacy of Bevacizumab in Recurrent Malignant Gliomas No drug interventions Not Available Not Available unknown_status NCT02876016
Cerebral Bases Bodily Representations No drug interventions basic_science Not Available unknown_status NCT05189366
Sophrology Treatment for Patients With Glial Tumours Requiring Speech Therapy No drug interventions supportive_care Not Available recruiting NCT04541082
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms No drug interventions treatment 1 recruiting NCT05139277
Evaluation of the CONVIVO System No drug interventions diagnostic Not Available recruiting NCT01655927
Efficacy of Tranexamic Acid in Brain Tumor Resections treatment 3 unknown_status NCT05804227
Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Low-Grade Gliomas in Adults treatment 0 recruiting NCT02332889
Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs treatment 1 / 2 terminated NCT03952598
Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy No drug interventions diagnostic Not Available recruiting NCT03557359
Nivolumab for Recurrent or Progressive IDH Mutant Gliomas treatment 2 active_not_recruiting NCT05054400
Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR treatment 0 withdrawn NCT03154996
Chronic Convection Enhanced Delivery of Topotecan treatment 1 completed NCT03091270
ZOOMit-fMRI Identifies Motor Functional Cortex No drug interventions Not Available Not Available recruiting NCT01961934
C11-Sodium Acetate PET/CT Imaging Evaluation in Brain Glioma, Post Therapy Necrosis and Pseudo-progression diagnostic 2 / 3 withdrawn NCT01517776
Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents treatment 2 terminated NCT01445691
More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery treatment 2 withdrawn NCT01251913
A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes No drug interventions Not Available Not Available terminated NCT01225003
Advanced MR Techniques in Detection of Tumor Infiltration and Grading in Gliomas No drug interventions Not Available Not Available completed NCT01144247
Cellular Immunotherapy Study for Brain Cancer No drug interventions treatment 1 completed NCT00967577
177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors treatment 1 completed NCT00832598
[18F] FACBC and [18F] FLT PET Imaging in Central Nervous System Tumors No drug interventions treatment Not Available completed NCT00589706
A Phase II Study of Adjuvant Use of Anti-Epidermal Growth Factor Receptor EGFR-425 in High Grade Gliomas No drug interventions treatment 2 completed NCT00200161
Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/Glioblastoma treatment 2 completed NCT03042416
18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety No drug interventions diagnostic 3 completed NCT03984240
The Effects of Mild Sedation on Motor Function Networks in Patients With Brian Gliomas treatment Not Available recruiting NCT05595863
Correlation Between SPECT/CT and IDH Mutation in Brain Glioma No drug interventions Not Available Not Available not_yet_recruiting NCT05593809
Single Photon Emission Computed Tomography/Computed Tomography With Pentavalent 99mTc Dimercaptosuccinic Acid in Patients With Brain Glioma; Correlation With IDH Mutation No drug interventions Not Available Not Available not_yet_recruiting NCT05157594
hPG80 (Circulating Progastrin) as a Blood Biomarker for High-grade Glial Tumors No drug interventions Not Available Not Available active_not_recruiting NCT04541225
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors No drug interventions treatment 1 terminated NCT00879437
Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma treatment 2 completed NCT02728024
Assessing Psychosocial and Supportive Care Needs in Patients With Gliomas No drug interventions Not Available Not Available completed NCT06563024
18F-FET PET/CT in the Management of Glioma No drug interventions diagnostic Not Available completed NCT05577416
A Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma treatment 0 recruiting NCT03295396
ONC201 in Adults With Recurrent H3 K27M-mutant Glioma treatment 2 active_not_recruiting NCT03626896
Safety of BBB Disruption Using NaviFUS System in Recurrent Glioblastoma Multiforme (GBM) Patients No drug interventions device_feasibility Not Available completed NCT00575796
Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs) treatment 2 unknown_status NCT05019196
fMRI Study of Functional Reorganization in Glioma Patients No drug interventions Not Available Not Available unknown_status NCT00028158
Safety and Effectiveness Study of G207, a Tumor-Killing Virus, in Patients With Recurrent Brain Cancer No drug interventions treatment 1 / 2 completed NCT02597335
Non Invasive Detection of IDH1/2 Mutation in Gliomas No drug interventions diagnostic Not Available unknown_status NCT05635435
Immune and Inflammatory Indices in Peripheral Blood Predict Prognosis of Glioma and Correlate With Grades and Subtypes No drug interventions Not Available Not Available recruiting NCT00454935
Correlation Between SV2A Expression in Tumour Tissue and Efficacy of Levetiracetam in Glioma Patients With Epilepsy No drug interventions Not Available Not Available unknown_status NCT00009035
Natural History of Patients With Brain and Spinal Cord Tumors No drug interventions Not Available Not Available completed NCT03193463
Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy treatment 0 withdrawn NCT04902586
Effect of Radiotherapy Concurrent of TTFields in Patients With Glioblastoma No drug interventions treatment Not Available unknown_status NCT01479686
iMRI Guided Resection in Cerebral Glioma Surgery No drug interventions treatment 3 completed NCT04521686
Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations treatment 1 active_not_recruiting NCT00122239
A Study of Gene Polymorphisms and Normal Tissue Radiation Injury in Patients Treated for Breast, Prostate, Brain, Lung, and Head and Neck Cancers No drug interventions Not Available Not Available unknown_status NCT02273739
Study of Orally Administered Enasidenib (AG-221) in Adults With Advanced Solid Tumors, Including Glioma, or Angioimmunoblastic T-cell Lymphoma, With an IDH2 Mutation treatment 1 / 2 completed NCT01595139
MicroRNAs in Patients With Neurofibromatosis Type 1 No drug interventions Not Available Not Available completed NCT04407039
Establishment and Evaluation of Multimodal Image Recognition System of Glioma Based on Deep Learning No drug interventions Not Available Not Available unknown_status NCT02122822
Research for Immunotherapy of Glioblastoma With Autologous Heat Shock Protein gp96 No drug interventions treatment 1 completed NCT00256425
Cognitive Rehabilitation of Glioma Patients No drug interventions treatment 3 unknown_status NCT06344130
Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma No drug interventions treatment 1 not_yet_recruiting NCT05310448
Tumor Treating Fields for the Treatment of Brainstem Gliomas No drug interventions treatment Not Available recruiting NCT01986348
Study Evaluating the Efficacy and Safety of Selinexor (KPT-330) in Participants With Recurrent Gliomas treatment 2 terminated NCT00001148
Detecting Malignant Brain Tumor Cells in the Bloodstream During Surgery to Remove the Tumor No drug interventions Not Available Not Available completed NCT00532948
A Study of Xeloda (Capecitabine) Plus Radiation Therapy in Children With Newly Diagnosed Gliomas treatment 1 completed NCT03212157
GlucoCEST MRI in Oncology No drug interventions basic_science Not Available completed NCT04205357
Sulfasalazine and Stereotactic Radiosurgery for Recurrent Glioblastoma treatment 1 completed NCT05773326
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG treatment 0 recruiting NCT00338026
A Phase I Study of ECO-4601 in Patients With Advanced Cancer treatment 1 completed NCT04424966
Infigratinib in Recurrent High-Grade Glioma Patients treatment 0 terminated NCT06043765
Reducing Cognitive Impairment in Glioma With Repetitive Transcranial Magnetic Stimulation and Cognitive Strategy Training No drug interventions treatment Not Available not_yet_recruiting NCT00795665
Bevacizumab and Carmustine in Treating Patients With Relapsed or Progressive High-Grade Glioma treatment 2 completed NCT05392374
Expanded Access Use of ONC201 in a Patient With Diffuse Intrinsic Pontine Gliomas Not Available Not Available no_longer_available NCT02115074
Safety of Fluvastatin-Celebrex Association in Low-grade and High Grade Optico-chiasmatic Gliomas treatment 1 completed NCT04539574
An Investigational Scan (7T MRI) for the Imaging of Central Nervous System Tumors No drug interventions diagnostic Not Available active_not_recruiting NCT02520882
68Ga-NOTA-Aca-BBN(7-14) PET/CT in Patients With Primary Gliomas No drug interventions diagnostic 0 unknown_status NCT05672082
Contribution of [18F]DPA-714 PET for Grading and Exploration of the Inflammatory Microenvironment of Glioma. No drug interventions diagnostic Not Available withdrawn NCT03134131
Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline High Grade Gliomas Not Available Not Available no_longer_available NCT06546631
Investigating Mechanistic Predictors of Interpatient Variability and Temozolomide (TMZ) Induced Haematological Toxicity for Glioma Patients No drug interventions Not Available Not Available not_yet_recruiting NCT01212731
Skull Base and Low Grade Glioma Neurocognitive Magnetic Resonance Imaging (MRI) Study No drug interventions Not Available Not Available completed NCT00040573
Safety and Tolerability Study of 131I-TM-601 to Treat Adult Patients With Recurrent Glioma. treatment 1 / 2 completed NCT05045027
Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma No drug interventions basic_science 0 recruiting NCT00977327
Comparison of Neuro-navigational Systems for Resection-Control of Brain Tumors No drug interventions treatment Not Available unknown_status NCT00350727
Pazopanib In Combination With Lapatinib In Adult Patients With Relapsed Malignant Glioma treatment 2 completed NCT05937776
Developing a New Metabolic Imaging Approach (aMRI) for Evaluating Neurological Disease in Patients With Gliomas No drug interventions Not Available Not Available recruiting NCT04065776
Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma No drug interventions treatment Not Available recruiting NCT00147160
Phase II Cisplatin + Temozolomide in Malignant Glial Tumours in Children and Adolescents treatment 2 completed NCT00870129
Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors No drug interventions diagnostic Not Available recruiting NCT02686229
Registry Study on Epidemiological and Biological Disease Profile as Well as Clinical Outcome in Patients With Low Grade Gliomas No drug interventions Not Available Not Available recruiting NCT03900689
Social Determinants of Health in Glioblastoma Population No drug interventions Not Available Not Available completed NCT00038389
Study of Vioxx and Radiation Therapy for Brainstem Glioma treatment 1 terminated NCT05464992
Use of CEST (Chemical Exchange Saturation Transfer) Imaging in PET/MRI No drug interventions other Not Available recruiting NCT03423992
Personalized Chimeric Antigen Receptor T Cell Immunotherapy for Patients With Recurrent Malignant Gliomas No drug interventions treatment 1 unknown_status NCT02433392
Study of Intraparenchymal Therapy as Adjunct Therapy in Patients With Recurrent, Resectable Glioblastoma Multiforme. No drug interventions treatment 1 terminated NCT01020292
A Trial of the Protease Inhibitor Nelfinavir and Concurrent Radiation and Temozolomide in Patients With WHO Grade IV Glioma treatment 1 completed NCT01229644
Study of Crenolanib, a Selective and Potent Inhibitor of PDGFR, for the Treatment of Adult Gliomas treatment 2 terminated NCT05770544
DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers. treatment 2 / 3 recruiting NCT04217044
Histopathology Images Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence No drug interventions Not Available Not Available recruiting NCT03741244
TMZ Plus Apatinib in Newly Diagnosed High-grade Glioma：RCT treatment 2 unknown_status NCT02854644
Study of the Anti-tumoral Immune Response No drug interventions basic_science Not Available completed NCT05990244
Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion No drug interventions diagnostic Not Available recruiting NCT06472440
Evaluation of the Use of a Method "Radiomics" for DOPA PET in Gliomas No drug interventions Not Available Not Available not_yet_recruiting NCT04752267
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases diagnostic 0 completed NCT03718767
Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype treatment 2 recruiting NCT02771301
Safety and Efficacy of IDH1R132H-DC Vaccine in Gliomas No drug interventions treatment Not Available unknown_status NCT01137604
A Study in Subjects With Recurrent Malignant Glioma treatment 2 completed NCT05958472
Navigating the Clinical Research Process for Glioma No drug interventions Not Available Not Available not_yet_recruiting NCT04953468
Expression of ANXA2 in the Extracellular Space in the Microenvironment of Periumoral Edema Promotes Glioma Invasion No drug interventions Not Available Not Available unknown_status NCT05025969
Evaluation of the Incidence of NTRK Gene Fusion in Adult Brain Tumours No drug interventions Not Available Not Available completed NCT04687969
Multimodal Machine Learning Characterization of Solid Tumors No drug interventions Not Available Not Available recruiting NCT00108069
Tamoxifen and Bortezomib to Treat Recurrent Brain Tumors treatment 2 completed NCT05039346
Quality of Life and Patient Needs in Advanced High Grade Gliomas No drug interventions Not Available Not Available completed NCT02444546
Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors treatment 1 completed NCT00526812
A Safety Study of RTA 744 in Patients With Recurrent High-Grade Gliomas treatment 1 completed NCT03971812
Organoids Derived From Induced-Pluripotent Stem Cells (iPS) From Patients With High Grade Astrocytoma No drug interventions Not Available Not Available unknown_status NCT02987010
Phase 2 Study of IDH305 in Low Grade Gliomas No drug interventions treatment 2 withdrawn NCT06368310
FIH Clinical Investigation of Graphene Electrodes for Brain Mapping No drug interventions device_feasibility Not Available not_yet_recruiting NCT04056910
Ivosidenib (AG-120) With Nivolumab in IDH1 Mutant Tumors treatment 2 completed NCT00979810
Image-Guided Stereotactic Biopsy of High Grade Gliomas diagnostic Not Available completed NCT03407781
IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Lower Grade Glioma No drug interventions diagnostic 1 completed NCT03181581
Improving Ultrasound Images in Brain Tumour Surgery With the Use of an Acoustic Coupling Fluid Mimicking Brain Tissue. No drug interventions diagnostic 2 terminated NCT05373381
The KetoGlioma (Ketogenic Glioma) Study No drug interventions other Not Available withdrawn NCT04391595
LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients treatment 0 recruiting NCT02783495
Feasibility And Efficacy Of An iPad-Based Cognitive Rehabilitation Program In Brain Tumor Patients No drug interventions treatment Not Available terminated NCT03843814
Pilot Study Using Amide Proton Transfer Magnetic Resonance Imaging Distinguishing Glioma No drug interventions diagnostic Not Available terminated NCT00409214
Phase IIa Safety and Light Dose-escalation Study in Patients With Primary or Recurrent/High-grade Glioma Using the Litxâ„¢ System to Confirm the Zone of Tumor Destruction During the Intraoperative Treatment of Glioma treatment 2 completed NCT02717455
Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma treatment 1 completed NCT03323450
Cognitive Remediation Therapy for Brain Tumor Patients: Improving Working Memory No drug interventions supportive_care Not Available completed NCT01743950
A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab treatment 2 active_not_recruiting NCT05555550
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG diagnostic 0 not_yet_recruiting NCT05486923
Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population No drug interventions Not Available Not Available recruiting NCT01081223
Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma No drug interventions treatment 1 / 2 completed NCT01166308
Carbon Ion Radiotherapy for Recurrent Gliomas No drug interventions treatment Not Available completed NCT02502708
Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors treatment 1 completed NCT05188508
Pembrolizumab, Olaparib, and Temozolomide for People With Glioma treatment 2 recruiting NCT02119338
5-ALA in Recurrent Glioma diagnostic Not Available unknown_status NCT02924038
A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG) treatment 1 terminated NCT00031538
Genetic Analysis of Brain Tumors No drug interventions Not Available Not Available terminated NCT05592743
Vorasidenib Expanded Access Program Not Available Not Available available NCT06099743
ASCENT Intervention for Brain Tumor Patients No drug interventions supportive_care Not Available not_yet_recruiting NCT00463203
Bevacizumab and Irinotecan for Patients With Primary Brain Tumors and Progression After Standard Therapy treatment 2 completed NCT01641003
Isolation and Characterization of Cancer Stem Cells Using iFP Technique No drug interventions Not Available Not Available unknown_status NCT06116903
Clinical Relevance of Detecting Molecular Abnormalities in Glial Tumor Exosomes No drug interventions diagnostic Not Available not_yet_recruiting NCT00107003
GW572016 to Treat Recurrent Malignant Brain Tumors treatment 2 completed NCT03102203
Differentiation of Progression From Treatment Effects in High-Grade Gliomas: A Clinical Trial With Multimodality MR Imaging No drug interventions Not Available Not Available unknown_status NCT05976490
NeuroPathways Intervention for Brain Tumor Patients No drug interventions supportive_care Not Available recruiting NCT05979064
Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) No drug interventions treatment Not Available recruiting NCT02795364
Study About the Validity of MRS-guided Resection on Prognosis High-grade Glioma Gliomas No drug interventions treatment Not Available unknown_status NCT04689321
Revision of the EORTC QLQ-BN20 Questionnaire No drug interventions Not Available Not Available unknown_status NCT04122521
Radiogenomic and Prognosis Analysis in Glioma No drug interventions Not Available Not Available unknown_status NCT00660621
A Phase II Study Of Gliadel, Concomitant Temozolomide And Radiation, Followed By Dose Dense Therapy With Temozolomide Plus Bevacizumab For Newly Diagnosed Malignant High Grade Glioma treatment 2 unknown_status NCT01263821
Image Guided Therapy in the Treatment of Gliomas No drug interventions diagnostic Not Available terminated NCT02941302
Multimodality Imaging Combined With Multiple Targets Pathological Examination for Detecting of Biological Borders of Gliomas: a Clinical Application Study No drug interventions treatment Not Available unknown_status NCT05345002
All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma treatment 2 recruiting NCT02658279
Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype treatment Not Available active_not_recruiting NCT06387979
Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer Using Pathology Biopsies No drug interventions Not Available Not Available recruiting NCT06575452
Using the Chemical Modifications Present on RNA Molecules to Diagnose and Treat Brain Cancer No drug interventions diagnostic Not Available not_yet_recruiting NCT03796273
Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases treatment 0 terminated NCT06572592
The Predictive Value of MRI for Adult-type Diffuse Gliomas No drug interventions Not Available Not Available not_yet_recruiting NCT01204684
Dendritic Cell Vaccine for Patients With Brain Tumors treatment 2 completed NCT03152318
A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 treatment 1 recruiting NCT05511324
Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma Patients No drug interventions supportive_care Not Available recruiting NCT06161519
PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications No drug interventions treatment 1 / 2 recruiting NCT01772771
Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program No drug interventions Not Available Not Available recruiting NCT04186832
Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy No drug interventions supportive_care Not Available recruiting NCT06413706
A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy treatment 2 not_yet_recruiting NCT02465060
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) screening 2 active_not_recruiting NCT03514069
Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma treatment 1 active_not_recruiting NCT06011109
Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab treatment 1 / 2 recruiting NCT02162732
Molecular-Guided Therapy for Childhood Cancer No drug interventions treatment Not Available completed NCT02372409
Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors treatment 2 terminated NCT03532295
Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas treatment 2 active_not_recruiting NCT04617002
Intermediate-size Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline Gliomas Not Available Not Available available NCT05355701
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations. treatment 1 recruiting NCT05580562
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) treatment 3 recruiting NCT05916313
A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3 No drug interventions treatment 1 recruiting NCT02073994
Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation treatment 1 completed NCT02781792
Temozolomide Chronotherapy for High Grade Glioma treatment 2 completed NCT05413304
Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis treatment 1 recruiting NCT02481154
Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation treatment 1 completed NCT03343197
Study of AG-120 and AG-881 in Subjects With Low Grade Glioma treatment 1 active_not_recruiting NCT04772456
Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas No drug interventions diagnostic 1 recruiting NCT05460507
Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment treatment 1 not_yet_recruiting NCT06512298
Plasticizer Exposure and Its Consequences on Health No drug interventions Not Available Not Available not_yet_recruiting NCT03991832
Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors treatment 2 recruiting NCT05576103
Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients No drug interventions Not Available Not Available recruiting NCT06326411
A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors No drug interventions treatment 1 recruiting NCT06355908
IL13Rα2 CAR-T for Patients With r/r Glioma No drug interventions treatment 1 recruiting NCT06397560
PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial No drug interventions treatment Not Available not_yet_recruiting NCT06496971
A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients treatment 3 not_yet_recruiting NCT01906385
Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT) treatment 1 / 2 recruiting NCT03095248
Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors treatment 2 suspended NCT03868943
Solriamfetol in Improving Sleep in Patients With Grade II-IV Glioma supportive_care 2 suspended NCT03975959
Memory Perception Assessment in Central/Non-central Nervous System Cancers No drug interventions supportive_care Not Available recruiting NCT06454097
Study on Radiogenomics Features Associated With Radiochemotherapy Sensitivity in Gliomas No drug interventions diagnostic Not Available recruiting NCT04373720
MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas No drug interventions diagnostic Not Available recruiting NCT05538130
A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors treatment 1 recruiting NCT03434262
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors treatment 1 completed NCT06412952
68Ga-NOTA-RM26 PET/CT in Glioma Patients No drug interventions diagnostic 0 recruiting NCT06417372
Intraoperative Fluorescent Staining Combined With Microsurgery for Gliomas No drug interventions Not Available Not Available not_yet_recruiting NCT04181684
LITT Followed by Hypofractionated RT for Recurrent Gliomas No drug interventions treatment Not Available recruiting NCT05383872
Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors No drug interventions diagnostic Not Available recruiting NCT05727605
Neurocognition After Radiotherapy in CNS- and Skull-base Tumors No drug interventions diagnostic Not Available recruiting NCT06408428
Glioma Intraoperative MicroElectroCorticoGraphy No drug interventions device_feasibility Not Available not_yet_recruiting NCT03964909
Resting-State Functional MRI in Glioma Patients Before and After Surgery No drug interventions diagnostic Not Available recruiting NCT05968053
Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi) No drug interventions Not Available Not Available recruiting NCT06381726
Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life No drug interventions treatment Not Available recruiting NCT02386241
Identification of Genomic Changes in Families Having Multiple Members With Tumors No drug interventions Not Available Not Available terminated NCT02481349
Couples-Based Yoga Program in Improving Quality of Life in Patients With High-Grade Glioma Undergoing Radiation Therapy and Their Partners No drug interventions supportive_care Not Available active_not_recruiting NCT04943913
Study on TIL for the Treatment of Brain Glioma No drug interventions treatment 0 recruiting NCT06368934
Sub-lobectomy for IDH Wild-type and TERT Promoter Mutant Glioblastoma No drug interventions treatment Not Available not_yet_recruiting NCT04745156
A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas No drug interventions device_feasibility Not Available not_yet_recruiting NCT06363162
Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery No drug interventions diagnostic Not Available recruiting NCT03739411
Hyperpolarized Imaging in Diagnosing Participants With Glioma No drug interventions diagnostic 1 recruiting NCT06036381
Spatial and Temporal Characterization of Gliomas Using Radiomic Analysis No drug interventions Not Available Not Available active_not_recruiting NCT06348693
Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness No drug interventions Not Available Not Available recruiting NCT02052648
Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors treatment 1 / 2 completed NCT04309552
Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma diagnostic 1 recruiting NCT04556929
Enhanced Detection in Glioma Excision No drug interventions diagnostic Not Available terminated NCT05182905
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients No drug interventions treatment 0 recruiting NCT06327048
Application of Cognitive Training Based on Remind Strategy in Glioma Patients With Cognitive Impairment No drug interventions other Not Available recruiting NCT06330337
Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma treatment 3 recruiting NCT06329570
Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM) treatment 1 / 2 not_yet_recruiting NCT03030066
Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas No drug interventions basic_science Not Available active_not_recruiting NCT03180502
Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma supportive_care 2 active_not_recruiting NCT03935269
Cereset for Caregivers No drug interventions supportive_care Not Available withdrawn NCT05500391
Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring No drug interventions health_services_research 2 recruiting NCT03048084
Seizure Treatment in Glioma treatment 4 recruiting NCT01638533
Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction treatment 1 active_not_recruiting NCT03551249
Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption No drug interventions treatment Not Available completed NCT04667715
Safety and Effectiveness of Blood-Brain Barrier Disruption (BBBD) in Subjects With Suspected Infiltrating Glioma No drug interventions treatment Not Available suspended NCT04699773
LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138) No drug interventions treatment Not Available recruiting NCT06234319
CXCR4 PET/MRI Targeted Imaging for Grading Diagnosis, Molecular Typing, and Prognostic Evaluation of Brain Glioma No drug interventions Not Available Not Available recruiting NCT06294418
FCI in Post-operative Low Grade Gliomas No drug interventions basic_science Not Available recruiting NCT02960230
H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas treatment 1 / 2 completed NCT05076513
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma treatment 0 recruiting NCT05604365
FearLess in Cognitively Intact Patients With Glioma No drug interventions supportive_care Not Available completed NCT06241391
Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas No drug interventions diagnostic Not Available not_yet_recruiting NCT01661400
Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors treatment 1 completed NCT04975139
Cognitive Changes of IDH-mutant and IDH-wildtype Glioma Patients After Chemoradiotherapy With Radiation Dose to the Resting State Networks No drug interventions Not Available Not Available recruiting NCT03684109
Non-invasive Glioma Characterization Through Molecular Imaging No drug interventions diagnostic Not Available recruiting NCT03687957
rhIL-7-hyFc on Increasing Lymphocyte Counts in Patients With Newly Diagnosed Non-severe Lymphopenic Gliomas Following Radiation and Temzolomide treatment 1 / 2 recruiting NCT04543201
Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade Glioma No drug interventions supportive_care Not Available recruiting NCT06199388
Development and Validation of a Deep Learning-Based Survival Prediction Model for Pediatric Glioma Patients: A Retrospective Study Using the SEER Database and Chinese Data No drug interventions Not Available Not Available completed NCT03500991
HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors No drug interventions treatment 1 active_not_recruiting NCT04185038
Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors No drug interventions treatment 1 recruiting NCT05686798
Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma. No drug interventions treatment 1 recruiting NCT06180434
Short Term Outcomes After PRoton And photoN radiOtherapy for IDH Mutated Grade 2 and 3 Gliomas No drug interventions Not Available Not Available not_yet_recruiting NCT05274919
Vascular Signature Mapping of Brain Tumor Genotypes No drug interventions Not Available Not Available recruiting NCT06156150
The Role of B7-H4 in Tumor Vaccine No drug interventions Not Available Not Available recruiting NCT04274283
Tessa Jowell BRAIN MATRIX - Platform Study No drug interventions Not Available Not Available recruiting NCT01502280
Fluorescence-guided Surgery for Low- and High-grade Gliomas treatment 3 completed NCT02717962
Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting treatment 2 active_not_recruiting NCT03149575
VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM treatment 3 terminated NCT03050736
Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression treatment 2 active_not_recruiting NCT03027388
Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma basic_science 2 completed NCT03706625
Integrated Discovery of New Immuno-Molecular Actionable Biomarkers for Tumors With Immune-suppressed Environment No drug interventions Not Available Not Available completed NCT04870580
[18F] FDOPA PET Imaging in Glioma: Feasibility Study for PET Guided Brain Biopsy No drug interventions diagnostic Not Available active_not_recruiting NCT05303519
Safusidenib Phase 2 Study in IDH1 Mutant Glioma treatment 2 recruiting NCT02800486
Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA treatment 2 recruiting NCT05352685
Effects of Propofol on Auditory Event-related Potentials and Brain Functional Connectivity in Patients With Supratentorial Glioma other Not Available recruiting NCT01491893
PVSRIPO for Recurrent Glioblastoma (GBM) treatment 1 completed NCT02549833
Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma treatment 1 active_not_recruiting NCT02833701
Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma treatment 1 terminated NCT03593993
A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas No drug interventions Not Available Not Available terminated NCT03638167
EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors No drug interventions treatment 1 active_not_recruiting NCT04931732
The circTeloDIAG: Liquid Biopsy for Glioma Tumor No drug interventions Not Available Not Available recruiting NCT05489783
Glioma Developmental and HyperActive Ras Tumor (DHART) Board No drug interventions Not Available Not Available recruiting NCT05768178
DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. treatment 2 / 3 recruiting NCT05873946
Assessing the Effectiveness of 2D Non-Navigated Intraoperative Ultrasound in Glioma Surgery No drug interventions Not Available Not Available completed NCT06043232
MMR/MSI Phenotypes in Prediction of Tumor Vaccine Benefit for Gliomas No drug interventions Not Available Not Available recruiting NCT06055517
Use of Pulsed Low-dose Rate Re-irradiation for Recurrent Glioma (PULSAR) No drug interventions treatment Not Available recruiting NCT06102837
Tumor Vaccines for Solid Tumors No drug interventions Not Available Not Available recruiting NCT04446416
Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients treatment Not Available completed NCT05607407
Methimazole in Patients With Progressive Glioblastoma treatment 2 recruiting NCT05964153
Analysis of Circulating DNA in Blood Samples of Glioma-affected Patients No drug interventions diagnostic Not Available recruiting NCT06018870
MRI Contrast Clearance Analysis for Glioma Grading and Genotyping No drug interventions Not Available Not Available recruiting NCT05386043
Registering Genomics and Imaging of Tumors (ReGIT) Not Available Not Available recruiting NCT05553041
18F-Fluciclovine PET-MRI in High-grade Glioma diagnostic 0 recruiting NCT04222309
Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) No drug interventions treatment 1 suspended NCT05512403
Evaluation of Diagnostic Performances of 18F-FDOPA PET KInetics No drug interventions diagnostic 3 recruiting NCT01682187
A Dose-Escalation Study in Participants With Recurrent Malignant Glioma treatment 1 active_not_recruiting NCT05901844
Evaluate the Accuracy of Raman IVD Analyzer in the Diagnosis of Gliomas During Surgery No drug interventions diagnostic Not Available not_yet_recruiting NCT02879682
nTMS for Motor Mapping of Rolandic Lesions No drug interventions diagnostic 2 / 3 completed NCT05062772
Brain Tumor Intraoperative Ultrasound Database No drug interventions Not Available Not Available recruiting NCT05875935
Assessment of Awake Surgery With Electrocorticographic Recordings in the Management of Gliomas and Correlation With Imaging Data (ECoG) No drug interventions screening Not Available terminated NCT05859659
Clinical, patHOlogical and Imaging Project of nEuro-oncology (HOPE) No drug interventions Not Available Not Available recruiting NCT05850377
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas Not Available Not Available not_yet_recruiting NCT05803057
Accelerating Motor Recovering in Patients With SMA Syndrome After Glioma Surgery by Using nrTMS No drug interventions treatment Not Available recruiting NCT04712214
Use of Non-invasive Optical Analysis in Neurosurgery No drug interventions other Not Available recruiting NCT03865355
Blood and Cerebrospinal Fluid Metabolomic Profile in Glioma Patients No drug interventions Not Available Not Available recruiting NCT05259605
Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification No drug interventions Not Available Not Available recruiting NCT05788445
High-frequency nrTMS on the Contralateral Broca Mirror Area for Glioma Patients With Early Postoperative Aphasia No drug interventions treatment Not Available not_yet_recruiting NCT03242824
The Utility of 18F-DOPA-PET in the Treatment of Recurrent High-grade Glioma treatment 2 completed NCT01792310
A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours No drug interventions treatment 1 / 2 completed NCT05739500
MRI-based Computer Aided Diagnosis Software (V1) for Glioma No drug interventions Not Available Not Available enrolling_by_invitation NCT04916015
Histomolecular Profiles of Gliomas in Children and Adolescent/Young Adults No drug interventions Not Available Not Available recruiting NCT05049148
Platelets Activation in Brain Neoplasms No drug interventions other Not Available recruiting NCT05707728
Evaluation of Role of Intraoperative Ultrasound in Gross Total Resection of Gliomas No drug interventions Not Available Not Available not_yet_recruiting NCT04233788
Metabolic Characterization of Space Occupying Lesions of the Brain No drug interventions Not Available Not Available recruiting NCT05700071
MRS of Glioma Genomics No drug interventions basic_science Not Available not_yet_recruiting NCT03072134
Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma No drug interventions treatment 1 completed NCT04097535
Measuring Fatty Acid Oxidation in Gliomas Using 18F-FPIA PET/MRI No drug interventions Not Available Not Available completed NCT05672043
Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China No drug interventions Not Available Not Available recruiting NCT05611645
Low-dose Bevacizumab With HSRT vs BVZ Alone for GBM at First Recurrence treatment 2 active_not_recruiting NCT05569434
68Ga-P16-093 PET/CT Imaging in Glioma Patients No drug interventions diagnostic 1 / 2 recruiting NCT05459441
Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases treatment 0 recruiting NCT05188534
ZOOMit-fMRI Identifies Language Functional Cortex No drug interventions Not Available Not Available not_yet_recruiting NCT05143775
Strategic Intervention on Preserving Language Function During Awake Craniotomy No drug interventions prevention Not Available not_yet_recruiting NCT05143788
Strategic Intervention on Preserving Motor Function During Awake Craniotomy No drug interventions treatment Not Available not_yet_recruiting NCT05140785
Mapping Molecular Markers of Brain Tumour Activity Using MRI No drug interventions other Not Available not_yet_recruiting NCT05133154
LIQUID BIOPSY IN Low-grade Glioma Patients No drug interventions other Not Available recruiting NCT05061251
Surgical Window of Opportunity Study of Orally Administered BAY 2402234 in Recurrent Glioma No drug interventions treatment 0 withdrawn NCT05028400
Intraoperative Laser Speckle Contrast Imaging to Assess Blood Flow During Neurosurgery No drug interventions treatment Not Available completed NCT04970615
Educating Brain Tumor Patients Using Patient-specific Actual-size Three-dimensional Printed Models No drug interventions Not Available Not Available recruiting NCT04809597
Does Notch Regulate Glioma Proliferation ? No drug interventions Not Available Not Available completed NCT04792437
Research on Precise Immune Prevention and Treatment of Glioma Based on Multi-omics Sequencing Data No drug interventions Not Available Not Available recruiting NCT04781764
The Study of Microglia/Macrophages Involved Dynamic Evolution of Glioma Microenvironment and the Function and Visualization of Targeted Molecules of Glioma No drug interventions Not Available Not Available recruiting NCT04738110
Post-operative Imaging in High Grade Glioma: is Management Influenced? No drug interventions Not Available Not Available recruiting NCT04719806
MR Textural Analysis in Low Grade Gliomas No drug interventions Not Available Not Available completed NCT04706338
Transcranial Magnetic Stimulation in the Rehabilitation of Postoperative Motor Dysfunction. No drug interventions treatment Not Available recruiting NCT04668508
Anlotinib to Malignant Brainstem Glioma treatment 2 recruiting NCT04550663
NKG2D CAR-T(KD-025) in the Treatment of Relapsed or Refractory NKG2DL+ Tumors treatment 1 not_yet_recruiting NCT04539431
Glioma Brain Tumours - E12513 - SensiScreen Glioma No drug interventions Not Available Not Available recruiting NCT04461002
Evaluation of the Correlation Between Molecular Phenotype and Radiological Signature (by PET-scanner and MRI) of Incident WHO II and III Grade Gliomas. No drug interventions Not Available Not Available enrolling_by_invitation NCT04425798
Connectivity Alterations After Levetiracetam Application No drug interventions Not Available Not Available unknown_status NCT04423094
Foci of Tumor Heterogeneity in Diffuse Low-Grade Gliomas No drug interventions Not Available Not Available completed NCT04388033
Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-naïve GBM Patients. treatment 1 / 2 recruiting NCT04220424
Glioma Patients Registry Based on Radiological, Histopathological and Genetic Analysis No drug interventions Not Available Not Available recruiting NCT04216537
Survival Significance of Molecular Pathology and Genetic Variation in Brain Gliomas No drug interventions Not Available Not Available recruiting NCT04217018
MR Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence No drug interventions Not Available Not Available recruiting NCT04215224
Histopathology Images Based Survival Prediction of Glioma Patients Using Artificial Intelligence No drug interventions Not Available Not Available recruiting NCT04215211
MR Based Survival Prediction of Glioma Patients Using Artificial Intelligence No drug interventions Not Available Not Available recruiting NCT04194593
Biomarker-based Algorithm for Diagnosis of Glioma No drug interventions Not Available Not Available unknown_status NCT04114370
Evaluation of 18F-fluciclovine (FACBC) PET/MR Uptake in Participants With Glioma other 0 completed NCT04055688
Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas Not Available Not Available completed NCT04051047
Gemcitabine in Newly-Diagnosed Diffuse Midline Glioma basic_science 0 withdrawn NCT04001257
18F-Fluoro-Ethyl-Tyrosine (FET) Positron Emission Tomography (PET) and Grading Glioma No drug interventions Not Available Not Available completed NCT03990597
StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord No drug interventions supportive_care 1 withdrawn NCT03973892
Remote Brain Microhaemorrhages May Predict Haematoma in Glioma Patients Treated With Radiation Therapy No drug interventions Not Available Not Available completed NCT03941626
Autologous CAR-T/TCR-T Cell Immunotherapy for Solid Malignancies No drug interventions treatment 1 / 2 recruiting NCT03877861
Validation of Readibandâ„¢ Actigraph and Associated Sleep/Wake Classification Algorithms No drug interventions Not Available Not Available completed NCT03722355
Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma treatment 3 completed NCT03716986
Multimodal Imaging of Hypoxia in Gliomas No drug interventions diagnostic Not Available unknown_status NCT03690570
Long Term Follow up of Patients Under 5 Years of Age With High Grade Glioma Diagnosed in France Between 1990 and 2015 No drug interventions Not Available Not Available unknown_status NCT03641391
Awake Intraoperative Language Mapping and Chinese Probabilistic Map Construction No drug interventions prevention Not Available not_yet_recruiting NCT03638206
Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies No drug interventions treatment 1 / 2 recruiting NCT03632317
A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With Gliomas treatment 2 withdrawn NCT03531333
Intraoperative Ultrasound Guided Glioma Surgery; a Randomised, Controlled Trial. No drug interventions treatment Not Available unknown_status NCT03463733
Hydroxy-urea and Temozolomide in Patients With a Recurrent Malignant Brain Tumor (Glioblastoma) treatment 1 unknown_status NCT03390062
A Study of Apatinib in Recurrent or Recurrent High-grade Glioma treatment 2 unknown_status NCT03352427
Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations treatment 2 terminated NCT03335280
68Ga-citrate PET/MR Imaging for Glioma No drug interventions Not Available Not Available terminated NCT03322813
ExAblate Blood Brain Barrier Disruption (BBBD) for Planned Surgery in Suspected Infiltrating Glioma No drug interventions treatment Not Available suspended NCT03257618
Quality of Life and Neurocognitive Functioning treatment Not Available completed NCT03168919
Image-Based Quantitative Assessment of Acute Radiation-Induced Changes in Glioma diagnostic Not Available terminated NCT03082846
Treatment of High-grade Gliomas Using Hypofractionated Radiation Therapy -a Phase I Clinical Trial treatment Not Available completed NCT03058198
The Research on 89Zr-ABT806 PET Imaging in High Grade Glioma No drug interventions diagnostic Not Available unknown_status NCT03009318
MRS and 11C-methionine PET/CT in the Diagnosis of Glioma No drug interventions diagnostic Not Available completed NCT02986815
[11C]Acetate PET in Patients With Glioma No drug interventions diagnostic Not Available terminated NCT02978261
Study of a c-Met Inhibitor PLB1001 in Patients With PTPRZ1-MET Fusion Gene Positive Recurrent High-grade Gliomas treatment 1 completed NCT02977689
Trial of IDH305 in IDH1 Mutant Grade II or III Glioma No drug interventions treatment 2 withdrawn NCT02919865
MR Perfusion Methods in Patients With Suspected Recurrent High Grade Gliomas No drug interventions treatment Not Available completed NCT02919332
Delayed 18F-FDG PET/CT in Improving Visualization of Brain Tumors in Patients With Glioblastoma No drug interventions Not Available Not Available withdrawn NCT02901925
A Microdose Evaluation Study of ABY-029 in Recurrent Glioma No drug interventions basic_science 0 completed NCT02805179
A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With Glioblastoma treatment 2 completed NCT02798406
Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects treatment 2 completed NCT02754362
A Toll-like Receptor Agonist as an Adjuvant to Tumor Associated Antigens (TAA) Mixed With Montanide ISA-51 VG With Bevacizumab for Patients With Recurrent Glioblastoma treatment 2 withdrawn NCT02747407
Qualitative, Qualitative, and Functional Studies Over the First Year in Measuring Immune System Response During the First Year of Therapy in Patients With Brain Tumors Not Available Not Available completed NCT02743078
Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma treatment 2 terminated NCT02713984
A Clinical Research of CAR T Cells Targeting HER2 Positive Cancer No drug interventions treatment 1 / 2 withdrawn NCT02689336
Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors treatment 2 withdrawn NCT02678975
Disulfiram in Recurrent Glioblastoma treatment 2 / 3 completed NCT02676687
Supratotal Resection for Gliomas Within Noneloquent Areas No drug interventions treatment Not Available unknown_status NCT02666066
Radiomics for Prediction of Survival in GBM No drug interventions Not Available Not Available completed NCT02652897
Hemostasis Alterations in Neurosurgical Patients No drug interventions Not Available Not Available unknown_status NCT02622620
Study on Neuroepithelial Tumor Grading and Pseudoprogression After Glioma Therapy Using Advanced Functional MRI Techniques No drug interventions Not Available Not Available unknown_status NCT02520492
Non Invasive Measurements of Intracranial Pressure in Patients With Malignant Glioma No drug interventions diagnostic Not Available completed NCT02518061
11C-Methionine PET as Prognostic Marker of Gliomas No drug interventions Not Available Not Available completed NCT02507232
Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas treatment 0 terminated NCT02496741
Metformin And Chloroquine in IDH1/2-mutated Solid Tumors treatment 1 / 2 completed NCT02481960
Study of Intraparenchymal Therapy With Irinotecan Drug Eluting Beads as Adjunct to Recurrent Surgically Resectable High Grade Glioma No drug interventions treatment 1 / 2 terminated NCT02454634
Phase I Trial of IDH1 Peptide Vaccine in IDH1R132H-mutated Grade III-IV Gliomas No drug interventions treatment 1 completed NCT02439164
Sedatives' Effects on Neurological Function in Patients With Eloquent Area Glioma other Not Available completed NCT02402075
Spinal Motor Evoked Potentials in Brain Surgery No drug interventions Not Available Not Available unknown_status NCT02387840
Feasibility and Clinically Application of Magnetic Resonance Fingerprinting No drug interventions diagnostic Not Available terminated NCT02371031
FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas No drug interventions diagnostic 1 terminated NCT02363075
Dexamfetamine Sulphate in Patients With Glioma Suffering From Severe Asthenia treatment 3 unknown_status NCT02345824
Early-Phase Study to Assess Inhibitor Ribociclib in Patients With Recurrent Glioblastoma or Anaplastic Glioma treatment 1 unknown_status NCT02327442
68Ga-NOTA-NFB: Radiation Dosimetry in Healthy Volunteers and Applications in Glioma Patients or Breast Cancer Patients No drug interventions Not Available Not Available unknown_status NCT02279992
Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases treatment 0 terminated NCT02272452
Assistance in Neurosurgery (ExtempoRMN) No drug interventions Not Available Not Available unknown_status NCT02253212
Safety of BBB Opening With the SonoCloud treatment 1 / 2 completed NCT02234297
Safety Study of BLZ-100 in Adult Subjects With Glioma Undergoing Surgery Not Available 1 completed NCT02176720
Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma No drug interventions diagnostic 1 terminated NCT02105233
Improving Ultrasound Images in Brain Tumor Surgery With the Use of Brain Mimicking Fluid No drug interventions diagnostic 1 completed NCT02099487
Hypofractionated Imrt (Vmat-Ra) For Elderly Patients With Newly Diagnosed High Grade Glioma No drug interventions treatment 2 completed NCT02082119
Hypofractionated IMRT With Temozolomide for HGG No drug interventions treatment Not Available completed NCT02029690
Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin treatment 1 terminated NCT02022800
Prospective Study on Oncologic Cerebral Imagery Contribution by 18F-FDOPA Position Emission Tomography (PET) No drug interventions diagnostic Not Available completed NCT02010606
Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma treatment 1 completed NCT01999270
Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors treatment 1 completed NCT01967810
ANG1005 in Patients With Recurrent High-Grade Glioma treatment 2 completed NCT01902771
Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors No drug interventions treatment 1 terminated NCT01861990
Valproic Acid in Childhood Progressive Brain Tumors treatment 1 withdrawn NCT01836536
Search for a Link Between Response to Treatment and Circulating Leucocytes in High Grade Glioma Patients basic_science Not Available completed NCT01813877
Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma No drug interventions diagnostic Not Available completed NCT01811524
The Etiology and Progression of Brain Tumors No drug interventions Not Available Not Available completed NCT01801852
Autologous Natural Killer T Cells Infusion for the Treatment of Cancer No drug interventions treatment Not Available unknown_status NCT01801371
68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma No drug interventions diagnostic 0 unknown_status NCT01798771
Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery No drug interventions treatment Not Available unknown_status NCT01778088
Open-Label Study of I-131-CLR1404 in Subjects With Recurrent Glioma treatment 2 withdrawn NCT01598454
Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides treatment 1 completed NCT01579253
Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients No drug interventions Not Available Not Available unknown_status NCT01567202
Study of DC Vaccination Against Glioblastoma No drug interventions treatment 2 unknown_status NCT01525459
Gene Expression, Immunological Status and Metabolome in Glioma Patients No drug interventions Not Available Not Available unknown_status NCT01502605
Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas diagnostic 1 terminated NCT01478178
Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma treatment 1 / 2 completed NCT01473485
ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors No drug interventions treatment Not Available active_not_recruiting NCT01465347
Safety and Efficacy of Trans Sodium Crocetinate (TSC) With Radiation and Temozolomide in Newly Diagnosed Glioblastoma treatment 1 / 2 completed NCT01460706
Imaging Malignant Glioma With 68Ga-DOTATOC PET/CT basic_science 2 / 3 completed NCT01450826
Emend and Ondansetron Compared to Ondansetron Alone to Prevent CINV in Glioma Patients Receiving Temozolomide treatment 2 completed NCT01403311
A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain No drug interventions treatment 2 unknown_status NCT01394692
Comparative Study of Intraoperative MRI-guided vs. Conventional Glioma Surgery No drug interventions treatment Not Available completed NCT01351519
A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors treatment 2 terminated NCT01331135
Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors treatment 1 completed NCT01220271
A Study Combining LY2157299 With Temozolomide-based Radiochemotherapy in Patients With Newly Diagnosed Malignant Glioma treatment 1 / 2 completed NCT01182883
A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors treatment 1 withdrawn NCT01158651
Everolimus for Children With NF1 Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas prevention 2 completed NCT01140568
Study of Platelet Derived Growth Factor Receptor (PDGFR) in Recurrent Malignant Gliomas treatment 2 completed NCT01138813
Development of Magnetic Resonance Spectroscopy (MRS) Biomarkers of Tumor Metabolism (MK-0000-145) No drug interventions Not Available Not Available completed NCT01125800
A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB treatment 1 / 2 completed NCT01116661
Safety Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Tumors of the Brain No drug interventions treatment 2 terminated NCT01044966
A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma treatment 1 / 2 terminated NCT00985036
Vascular Endothelial Growth Factor (VEGF) Levels in Brain Tumor Patients No drug interventions Not Available Not Available withdrawn NCT00979173
Pharmacokinetics (PK) Study of AC480 for Recurrent Glioma treatment 1 completed NCT00939315
Multimodal Diagnostic Assessment of Cerebral Gliomas With FET & FCH PET/CT, and Magnetic Resonance Imaging/Spectroscopy No drug interventions Not Available Not Available completed NCT00909558
Safety and Effectiveness Study of Autologous Natural Killer and Natural Killer T Cells on Cancer No drug interventions treatment 1 suspended NCT00880061
An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma treatment 1 terminated NCT00815152
Coping With High Grade Glioma No drug interventions supportive_care Not Available terminated NCT00813787
Investigation Into the Differentiation of Tumour and Healthy Brain Tissue Using Multi-exponential T2 Components No drug interventions Not Available Not Available unknown_status NCT00795457
Effects of Vaccinations With HLA-A2-Restricted Glioma Antigen-Peptides in Combination With Poly-ICLC for Adults With High-Risk WHO Grade II Astrocytomas and Oligo-Astrocytomas treatment 0 completed NCT00782626
Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas treatment 2 completed NCT00734864
Ph. I Dasatinib/Protracted Temozolomide in Recurrent Malignant Glioma No drug interventions treatment 1 withdrawn NCT00727506
BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant Glioma treatment 2 completed NCT00723827
Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2) Not Available Not Available completed NCT00705198
Temozolomide All-Case-Registered Surveillance (Designated Drug Use Investigation)(Study P05062) Not Available Not Available completed NCT00694330
Vaccination With Lethally Irradiated Glioma Cells Mixed With GM-K562 Cells in Patients Undergoing Craniotomy For Recurrent Tumor No drug interventions treatment 1 completed NCT00686387
Establishment of a Brain and Spinal Tumor Tissue Bank No drug interventions Not Available Not Available unknown_status NCT00660283
A Phase II Study of Gliadel, Concomitant Temozolomide and Radiation, Followed By Dose Dense Therapy With Temozolomide For Newly Diagnosed Malignant High Grade Glioma treatment 2 unknown_status NCT00424554
Low-dose Temozolomide for 2 Weeks on Brain Tumor Enzyme in Patients With Gliomas (P04602 AM1) (Completed) treatment 2 completed NCT00418899
Gliogene: Brain Tumor Linkage Study No drug interventions Not Available Not Available unknown_status NCT00412542
Thalidomide and Temozolomide or Camptothecin-11 (CPT-11) in Patients With Gliomas treatment 2 completed NCT00404495
Combination of Irinotecan and Temozolomide in Children With Brain Tumors. treatment 2 completed NCT00392171
The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601) treatment 2 completed NCT00389090
A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma treatment 2 terminated NCT00379132
131-I-TM-601 Study in Adults With Solid Tumors treatment 1 completed NCT00360828
Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas diagnostic 2 terminated NCT00352820
Experience of Brain Tumor Caregivers No drug interventions Not Available Not Available completed NCT00339352
A Family Study of Adults With Glioma No drug interventions Not Available Not Available completed NCT00330109
Identification of Clinically Occult Glioma Cells and Characterization of Glioma Behavior Through Machine Learning Analysis of Advanced Imaging Technology No drug interventions diagnostic Not Available unknown_status NCT00250211
Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide No drug interventions treatment 1 / 2 completed NCT00214175
Determination of Fraction Size Equivalent Dose (FED) Levels for Intracranial Conformal Avoidance Radiotherapy No drug interventions Not Available Not Available completed NCT00213278
Phase 2 Study of Vinblastine in Children With Recurrent or Refractory Low Grade Glioma treatment 2 completed NCT00185848
Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis No drug interventions diagnostic 1 completed NCT00165360
Prolonged Daily Temozolomide for Low-Grade Glioma treatment 2 completed NCT00137488
Angiogenic Profile and Non-invasive Imaging May Predict Tumor Progression of High Risk Group Low Grade Glioma (LGG) No drug interventions Not Available Not Available completed NCT00108056
Enzastaurin to Treat Recurrent Brain Tumor treatment 1 terminated NCT00080054
A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas treatment 1 completed NCT00059020
The Role of Gene Changes in Brain Tumor Formation and Growth No drug interventions Not Available Not Available completed NCT00047879
Phase II Trial of Peginterferon Alpha-2b and Thalidomide in Adults With Recurrent Gliomas treatment 2 completed NCT00045968
Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer treatment 3 active_not_recruiting NCT00038441
Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas treatment 1 / 2 completed NCT00001502
A Pediatric Phase I Trial of RMP-7 and Carboplatin in Brain Tumors treatment 1 completed NCT00001573
A Phase I Study of SU101 in Pediatric Patients With Refractory Malignancy treatment 1 completed NCT00001171
Evaluation of Factors in Human Brain Tumors No drug interventions Not Available Not Available completed NCT06018363
Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection No drug interventions treatment 1 / 2 recruiting