Glycosides
- Name
- Glycosides
- Accession Number
- DBCAT000257
- Description
Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)
- Drugs
Drug Drug Description 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Oxadiazole Not Available 2'-Deoxy-thymidine-beta-L-rhamnose Not Available 3-O-Methyl-d-glucose Not Annotated 4-methylumbelliferyl beta-D-glucoside Not Annotated 4-nitrophenyl-beta-D-galactoside Not Available Acetyldigitoxin Used for fast digitalization in congestive heart failure. Acetyldigoxin Not Annotated Aclarubicin Not Annotated Acrihellin Acrihellin is a small molecule drug. Acrihellin has a monoisotopic molecular weight of 498.26 Da. Acteoside Acteoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy). Actodigin Actodigin is a small molecule drug. Actodigin has a monoisotopic molecular weight of 536.3 Da. Adenosine A medication used in myocardial perfusion scintigraphy and to treat supraventricular tachycardia. Aklavine Aklavine is under investigation in clinical trial NCT03026842 (Decitabine Versus Conventional Chemotherapy for Maintenance Therapy of Acute Myeloid Leukemia With T(8;21)). Aldoxorubicin Investigated for use/treatment in solid tumors. AM365 Investigated for use/treatment in hepatitis (viral, B). Amikacin An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria. Amphotericin B An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis. Amrubicin Investigated for use/treatment in lung cancer . Annamycin Investigated for use/treatment in breast cancer and leukemia (unspecified). Anthelmycin Anthelmycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Anthelmycin is a antibiotic, produced by Streptomyces strain. Anthelmycin has a monoisotopic... Apramycin An aminoglycoside antibiotic for veterinary use that is used to treat infections in animals. Arbekacin Arbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA). Arbutin Indicated for over-the-counter use for epidermal hyperpigmentation in various skin conditions, such as melasma, freckles, and senile lentigines. Atigliflozin Atigliflozin is a small molecule drug. Atigliflozin is under investigation in clinical trial NCT00361738 (Dose-Ranging Study Evaluating AVE2268 in Patients With Type 2 Diabetes Not Adequately Controlled by a Metformin... Avicin D Not Annotated Azathioprine An immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis. Balapiravir Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic. Becatecarin Investigated for use/treatment in cancer/tumors (unspecified), liver cancer, gastric cancer, and leukemia (unspecified). Beciparcil Beciparcil is a small molecule drug. Beciparcil has a monoisotopic molecular weight of 283.03 Da. Bekanamycin An aminoglycoside antibiotic indicated in the treatment of eye infections. Berubicin Not Annotated Beta-D-Glucose A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically... beta-Escin An anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma. Bexagliflozin A sodium-glucose co-transporter 2 inhibitor used to improve glycemic control in patients with type 2 diabetes mellitus. Bilberry Not Annotated Bluensomycin Bluensomycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Bluensomycin is a antibiotic, produced by Streptomyces strain. Bluensomycin has a monoisotopic... Bufogenin Bufogenin is a small molecule drug. Bufogenin has a monoisotopic molecular weight of 384.23 Da. Camsirubicin GPX-150 has been used in trials studying the treatment of Soft Tissue Sarcoma and Advanced Solid Tumors - Phase 1 Population. Carboxyatractyloside Not Available Chloralose Chloralose is a small molecule drug. Chloralose has a monoisotopic molecular weight of 307.96 Da. Clindamycin A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria. Clorobiocin Clorobiocin is an aminocoumarin antibiotic, similar to novobiocin and coumermycin A1. CMB-401 Not Annotated Cyclohexyl-pentyl-maltoside Not Available Cymarin Not Annotated Dapagliflozin A sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus. Daunorubicin An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia. Decitabine A chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation and corresponding alterations in gene expression. Deslanoside For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure. Dibekacin Dibekacin is an aminoglycoside antibiotic marketed in Japan . Digitoxigenin Digitoxigenin is a cardenolide which is the aglycon of digitoxin. Digitoxin A cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. Digoxigenin Digoxigenin is a cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh. Digoxin A cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. Dihydrostreptomycin Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin... Doranidazole Not Annotated Doxorubicin A medication used to treat various cancers, including AIDS-associated Kaposi's Sarcoma and metastatic cancers. DTS-201 Investigated for use/treatment in cancer/tumors (unspecified). Elsamitrucin Investigated for use/treatment in lymphoma (non-hodgkin's). Empagliflozin An SGLT2 inhibitor used to manage type 2 diabetes mellitus. Emtricitabine A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. Epirubicin An anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer. Escin An anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma. Esculamine Esculamine is a small molecule drug. Esculamine has a monoisotopic molecular weight of 309.12 Da. Esculin As medication, esculin is sometimes used as a vasoprotective agent. Esculin is also used in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria),... Etoposide A podophyllotoxin derivative used to treat testicular and small cell lung tumors. Evernimicin Investigated for use/treatment in bacterial infection. Framycetin An aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus. Galactose-uridine-5'-diphosphate A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides,... Galidesivir Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus. In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various... Gancotamab Gancotamab is under investigation in clinical trial NCT02213744 (MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients). Gemcitabine A nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer. Gemtuzumab ozogamicin A monoclonal anti-CD33 antibody used to treat CD33-positive acute myeloid leukemia. Geneticin Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both... Gentamicin An aminoglycoside used to treat a wide variety of aerobic infections in the body. Gentamicin C1a Not Available Gentamicin C2 Not Annotated Ginsenoside B2 Ginsenoside B2 is under investigation in clinical trial NCT00781534 (A Clinical Trial of Ginseng in Diabetes). Ginsenoside C Not Available Ginsenoside Rb1 Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as... Ginsenoside Rd Ginsenoside Rd is under investigation in clinical trial NCT00815763 (Efficacy and Safety of Ginsenoside-rd for Acute Ischemic Stroke). Ginsenoside Rg1 Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as... Ginsenoside Rg3 Ginsenoside Rg3 is under investigation in clinical trial NCT01757366 (Safety and Efficacy of Ginsenoside Rg3 in Combination With First-line Chemotherapy in Advanced Gastric Cancer). Ginsenosides Dammarane type triterpene saponins based mainly on the aglycones, protopanaxadiol and protopanaxatriol. Gitoformate Not Annotated Glucoraphanin Glucoraphanin is under investigation in clinical trial NCT01879878 (Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]). GPI-0100 Investigated for use/treatment in breast cancer, kidney cancer, leukemia (myeloid), melanoma, neuroblastoma, ovarian cancer, and prostate cancer. Hesperetin For lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase... Hesperidin A bioflavonoid found in a variety of nutritional supplements that is touted to have various beneficial effects on blood vessel disorders and various other conditions. Hesperidin methylchalcone Not Annotated Hygromycin B Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. Idarubicin An anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults. Inotuzumab ozogamicin An antibody-drug conjugate used to treat B-cell precursor acute lymphoblastic leukemia (ALL). Ipragliflozin Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2. Isepamicin Not Annotated Isopropyl beta-D-thiogalactopyranoside A non-metabolizable galactose analog that induces expression of the LAC operon. Isoquercetin Isoquercetin has been used in trials studying the treatment of Kidney Cancer, Renal cell carcinoma, Advanced Renal Cell Carcinoma, Thromboembolism of Vein in Pancreatic Cancer, and Thromboembolism of Vein VTE... Kanamycin An aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. KP-1461 Investigated for use/treatment in HIV infection. Ladirubicin Ladirubicin is a small molecule drug. Ladirubicin has a monoisotopic molecular weight of 601.16 Da. Lanatoside C Not Annotated Lincomycin An antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate. Maribavir A cytomegalovirus (CMV) pUL97 kinase inhibitor used for the treatment of refractory post-transplant CMV infection. Matrix-M Matrix-M is a saponin-based adjuvant made of nanometer particles, cholesterol, and phospholipid that is developed by Novavax. This compound is administered alongside vaccines to enhance biological functions: creating robust and... Me-4(18F)DG Me-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer). methyl beta-D-glucopyranoside Not Available Methyl beta-galactoside Not Available Metildigoxin A digitalis glycoside indicated in the treatment of acute and chronic heart failure. Metrizamide Metrizamide is used for lumbar, thoracic, cervical, and total columnar myelography to determine the presence of abnormalities in the spinal column, spinal canal, and central nervous system (CNS) as well... Micronomicin Micronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina. Mizagliflozin Mizagliflozin is under investigation in clinical trial NCT05721729 (Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions). N4-Hydroxycytidine A cytidine analog being investigated to treat COVID-19. Nanoparticle Epirubicin Nanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma). It is a novel epirubicin... Naroparcil Naroparcil is a small molecule drug. Naroparcil has a monoisotopic molecular weight of 387.06 Da. NC-6300 NC-6300, also known as K-912, is a novel epirubicin drug-conjugated polymeric micelle. Neamine Not Available Neomycin An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body. Netilmicin An aminoglycoside used to treat a wide variety of infections in the body. Nikkomycin Z Nikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis. Nogalamycin Nogalamycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Nogalamycin is a antibiotic, produced by Streptomyces strain. Nogalamycin has a monoisotopic... Novobiocin For the treatment of infections due to staphylococci and other susceptible organisms octyl beta-D-galactopyranoside Not Available Oleandrin Oleandrin has been used in trials studying the treatment of Lung Cancer and Chemotherapeutic Agent Toxicity. Olitigaltin Olitigaltin has been investigated for the treatment of Idiopathic Pulmonary Fibrosis. Ouabain For the treatment of atrial fibrillation and flutter and heart failure Pamaqueside Pamaqueside is a small molecule drug. Pamaqueside has a monoisotopic molecular weight of 754.41 Da. Paromomycin An aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma. Pegaptanib A selective vascular endothelial growth factor (VEGF) antagonist used for the treatment of neovascular (wet) age-related macular degeneration. Peoniflorin Peoniflorin is under investigation in clinical trial NCT02878863 (Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune Hepatitis). Peruvoside Not Annotated Phlorizin Not Annotated Pirarubicin Not Annotated Pirlimycin Pirlimycin hydrochloride is an antibiotic belonging to the lincosamide class. Often marketed as Pirsue, this drug is used to treat mastitis in cattle. Plazomicin An aminoglycoside antibiotic used to treat complicated urinary tract infections. Plicamycin For the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer. Polydatin Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin... Propikacin Propikacin is a small molecule drug. Propikacin has a monoisotopic molecular weight of 557.29 Da. Proscillaridin Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin,... PSI-352938 PSI-352938 has been used in trials studying the treatment of Hepatitis C and Hepatitis C, Chronic. Puromycin Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting... QS-21 Investigated for use/treatment in genital herpes, HIV infection, hepatitis (viral, B), influenza, malaria, melanoma, and viral infection. R1626 Investigated for use/treatment in hepatitis (viral, C). Remdesivir A nucleoside analog used to treat RNA virus infections including COVID-19. Remogliflozin etabonate Remogliflozin etabonate has been used in trials studying the treatment and basic science of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2. Ribavirin monophosphate Not Annotated Ribostamycin A broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine. Sabarubicin Sabarubicin has been used in trials studying the treatment of Prostate Cancer, Testicular Germ Cell Tumor, and Unspecified Adult Solid Tumor, Protocol Specific. Salicin Not Annotated Sennosides A laxative used to treat constipation. Sergliflozin etabonate Sergliflozin etabonate is a small molecule drug. Sergliflozin etabonate has a monoisotopic molecular weight of 448.17 Da. Sisomicin Sisomicin has been used in trials studying the treatment of Pyoderma. SP1049C Intended for the treatment of carcinoma of the oesophagus. Spectinomycin An aminocyclitol antibiotic used to treat susceptible strains of Neisseria gonorrhoeae. Spiramycin A macrolide antimicrobial agent used in the treatment of various bacterial infections. Steffimycin Steffimycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Steffimycin is a antibiotic, produced by Streptomyces strain. Steffimycin has a monoisotopic... Stevioside Not Annotated Streptolydigin Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci. Streptomycin An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. Streptozocin A nitrosourea antineoplastic agent used in the treatment of metastatic pancreatic islet cell carcinoma. Sucralfate A gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence. Telavancin An antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia. Teniposide A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia. Thiocellobiose Not Available Thiodigalactoside Thiodigalactoside is a solid. This compound belongs to the dihexoses. These are disaccharides containing two hexose carbohydrates. This medication is known to target galectin-1, heat-labile enterotoxin b chain, neurocan core... Ticagrelor A P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death. Tobramycin An aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections. Tofogliflozin Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2. Tricetin Not Available UDP-alpha-D-glucuronic acid A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides.... Uridine diphosphate glucose A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and... Valrubicin An anthracycline used intravesically in the treatment of BCG-resistant bladder carcinoma. Vidarabine An antiviral agent used to treat various viral infections. Volanesorsen An antisense oligonucleotide indicated to treat familial chylomicronemia. Zoptarelin doxorubicin Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others. Zorubicin Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types. - Drugs & Drug Targets