Sinusitis

Also known as: Highmoritis / Sinusitis (disorder) / Sinus infection / Sinusitis NOS / Chronic sinusitis

DrugDrug NameDrug Description
DB00316AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DB06151AcetylcysteineA medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose.
DB01060AmoxicillinA penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
DB01114ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB00766Clavulanic acidA beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
DB15881ClonazolineNot Annotated
DB09357DexpanthenolAn alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
DB08801DimetindeneA 1st generation selective H1 antagonist used topically as an antipruritic and orally to treat allergies.
DB00764MometasoneA corticosteroid with no indications.
DB09285MorniflumateAn NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems.
DB00218MoxifloxacinA fluoroquinolone antibiotic used to treat various bacterial infections.
DB06711NaphazolineA sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion.
DB00788NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
DB13216OxolamineA medication indicated in the treatment of a cough or upper respiratory tract inflammation.
DB00388PhenylephrineAn alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics.
DB09209PholcodineAn opioid antitussive used to suppress unproductive coughing.
DB00852PseudoephedrineAn alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.
DB16362Silver proteinateA nasal decongestant and antiseptic of the nasal and ear canals.
DB09153Sodium chlorideAn ingredient found in a variety of nutritional products as a source of electrolytes and water.
DB06764TetryzolineAn alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion.
DB06694XylometazolineA direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds.
DrugDrug NameTargetType
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenATP-dependent translocase ABCB1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1A1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1A9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin E synthase 3target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenAlbumincarrier
DB00316AcetaminophenFatty-acid amide hydrolase 1enzyme
DB00316AcetaminophenGlutathione S-transferase Penzyme
DB00316AcetaminophenGlutathione S-transferase Mu 1enzyme
DB00316AcetaminophenSodium-dependent noradrenaline transportertarget
DB00316AcetaminophenSodium-dependent serotonin transportertarget
DB06151AcetylcysteineSolute carrier organic anion transporter family member 1B1transporter
DB06151AcetylcysteineNAPQI (N-acetyl-p-benzoquinone imine)target
DB06151AcetylcysteineSolute carrier family 22 member 6transporter
DB06151AcetylcysteineAminoacylase-1target
DB06151AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB06151AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB06151AcetylcysteineGlutathione synthetasetarget
DB06151AcetylcysteineCystine/glutamate transportertarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 2Btarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 1target
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 2Atarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 2Dtarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 3Atarget
DB06151AcetylcysteineAlbumincarrier
DB06151AcetylcysteineAminoacylase-1enzyme
DB01060AmoxicillinSolute carrier family 15 member 1transporter
DB01060AmoxicillinSolute carrier family 15 member 2transporter
DB01060AmoxicillinSolute carrier family 22 member 6transporter
DB01060AmoxicillinCytochrome P450 2C8enzyme
DB01060AmoxicillinAlbumincarrier
DB01060AmoxicillinBeta-lactamase 2enzyme
DB01060AmoxicillinPenicillin binding proteintarget
DB01114ChlorpheniramineHistamine H1 receptortarget
DB01114ChlorpheniramineCytochrome P450 3A4enzyme
DB01114ChlorpheniramineCytochrome P450 2D6enzyme
DB01114ChlorpheniramineSodium-dependent serotonin transportertarget
DB01114ChlorpheniramineSodium-dependent noradrenaline transportertarget
DB01114ChlorpheniramineSodium-dependent dopamine transportertarget
DB01114ChlorpheniramineCytochrome P450 3A5enzyme
DB01114ChlorpheniramineCytochrome P450 3A7enzyme
DB01114ChlorpheniramineSolute carrier family 22 member 2transporter
DB01114ChlorpheniramineSolute carrier family 22 member 1transporter
DB00766Clavulanic acidBacterial beta-lactamase enzymestarget
DB00766Clavulanic acidSodium/glucose cotransporter 1transporter
DB00766Clavulanic acidBeta-lactamasetarget
DB08801DimetindeneMuscarinic acetylcholine receptor M2target
DB08801DimetindeneHistamine H1 receptortarget
DB00764MometasoneGlucocorticoid receptortarget
DB00764MometasoneCytochrome P450 2C8enzyme
DB00764MometasoneProgesterone receptortarget
DB00764MometasoneCytochrome P450 3A4enzyme
DB00764MometasoneCytochrome P450 3A5enzyme
DB09285MorniflumatePolyunsaturated fatty acid 5-lipoxygenasetarget
DB09285MorniflumateProstaglandin G/H synthase 2target
DB09285MorniflumatePolyunsaturated fatty acid 5-lipoxygenaseenzyme
DB09285MorniflumateProstaglandin G/H synthase 2enzyme
DB09285MorniflumateLeukotriene B4 receptor 1target
DB09285MorniflumateThromboxane A2 receptortarget
DB09285MorniflumateUDP-glucuronosyltransferase 1A9enzyme
DB09285MorniflumateProstaglandin G/H synthase 1target
DB00218MoxifloxacinDNA gyrase subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 4 subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 2-alphatarget
DB00218MoxifloxacinCytochrome P450 1A2enzyme
DB00218MoxifloxacinSerum paraoxonase/arylesterase 1target
DB00218MoxifloxacinDNA gyrase subunit Atarget
DB00218MoxifloxacinDNA gyrase subunit Btarget
DB06711NaphazolineAlpha-1A adrenergic receptortarget
DB06711NaphazolineAlpha-2A adrenergic receptortarget
DB06711NaphazolineD(2) dopamine receptortarget
DB00788NaproxenProstaglandin G/H synthase 1target
DB00788NaproxenProstaglandin G/H synthase 2target
DB00788NaproxenAlbumincarrier
DB00788NaproxenCytochrome P450 2C9enzyme
DB00788NaproxenCytochrome P450 1A2enzyme
DB00788NaproxenSolute carrier organic anion transporter family member 1A2transporter
DB00788NaproxenSolute carrier family 22 member 6transporter
DB00788NaproxenCytochrome P450 2C8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 2B7enzyme
DB00788NaproxenPeptostreptococcal albumin-binding proteintarget
DB00788NaproxenBile salt export pumptransporter
DB00788NaproxenATP-dependent translocase ABCB1transporter
DB00788NaproxenUDP-glucuronosyltransferase 1A3enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-6enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1A7enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1A8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1A9enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1A10enzyme
DB00788NaproxenOrganic anion transporter 3transporter
DB00788NaproxenPancreatic triacylglycerol lipasetarget
DB00388PhenylephrineAlpha-1A adrenergic receptortarget
DB00388PhenylephrineAlpha-1B adrenergic receptortarget
DB00388PhenylephrineAmine oxidase [flavin-containing] Aenzyme
DB00388PhenylephrineAlpha-1D adrenergic receptortarget
DB00388PhenylephrineCytochrome P450 1A2enzyme
DB00388PhenylephrineSulfotransferase 1A3enzyme
DB00388PhenylephrineAmine oxidase [flavin-containing] Benzyme
DB00388PhenylephrineD(2) dopamine receptortarget
DB09209PholcodineMu-type opioid receptortarget
DB09209PholcodineKappa-type opioid receptortarget
DB09209PholcodineDelta-type opioid receptortarget
DB00852PseudoephedrineAlpha-1A adrenergic receptortarget
DB00852PseudoephedrineAlpha-2A adrenergic receptortarget
DB00852PseudoephedrineBeta-2 adrenergic receptortarget
DB00852PseudoephedrineAmine oxidase [flavin-containing] Aenzyme
DB00852PseudoephedrineBeta-1 adrenergic receptortarget
DB00852PseudoephedrineSodium-dependent dopamine transportertarget
DB00852PseudoephedrineSodium-dependent noradrenaline transportertarget
DB00852PseudoephedrineSodium-dependent serotonin transportertarget
DB00852PseudoephedrineNuclear factor of activated T-cells, cytoplasmic 1target
DB00852PseudoephedrineTumor necrosis factortarget
DB00852PseudoephedrineNuclear factor NF-kappa-B p105 subunittarget
DB00852Pseudoephedrineactivator protein 1target
DB00852PseudoephedrineInterleukin-2target
DB00852PseudoephedrineAlbumincarrier
DB00852PseudoephedrineSodium-dependent noradrenaline transportertransporter
DB00852PseudoephedrineSodium-dependent dopamine transportertransporter
DB00852PseudoephedrineSodium-dependent serotonin transportertransporter
DB00852PseudoephedrineD(2) dopamine receptortarget
DB06764TetryzolineAlpha-1 adrenergic receptorstarget
DB06764TetryzolineAlpha-2 adrenergic receptorstarget
DB06764TetryzolineAlpha-2C adrenergic receptortarget
DB06694XylometazolineAlpha-2A adrenergic receptortarget
DB06694XylometazolineAlpha-1A adrenergic receptortarget
DB06694XylometazolineAlpha-1B adrenergic receptortarget
DB06694XylometazolineAlpha-1D adrenergic receptortarget
DB06694XylometazolineAlpha-2B adrenergic receptortarget
DB06694XylometazolineAlpha-2C adrenergic receptortarget
DrugDrug NamePhaseStatusCount
DB01060AmoxicillinNot AvailableCompleted5
DB00207AzithromycinNot AvailableCompleted2
DB00626BacitracinNot AvailableWithdrawn1
DB01222BudesonideNot AvailableCompleted1
DB00341CetirizineNot AvailableCompleted1
DB00766Clavulanic acidNot AvailableCompleted5
DB00588Fluticasone propionateNot AvailableCompleted1
DB00635PrednisoneNot AvailableCompleted1
DB00852PseudoephedrineNot AvailableCompleted2
DB01015SulfamethoxazoleNot AvailableCompleted1
DB00620TriamcinoloneNot AvailableCompleted1
DB00440TrimethoprimNot AvailableCompleted1
DB00661VerapamilNot AvailableTerminated1
DB00558ZanamivirNot AvailableCompleted1
DB01167Itraconazole1Completed1
DB00661Verapamil1Terminated1
DB00468Quinine1 / 2Terminated1
DB00207Azithromycin2Completed1
DB00394Beclomethasone dipropionate2Withdrawn1
DB01222Budesonide2Withdrawn1
DB01112Cefuroxime2Withdrawn1
DB00003Dornase alfa2Completed1
DB12159Dupilumab2Completed1
DB00874Guaifenesin2Withdrawn1
DB00852Pseudoephedrine2Withdrawn1
DB01222Budesonide2 / 3Completed1
DB11114Eucalyptus oil2 / 3Completed1
DB00959Methylprednisolone2 / 3Completed1
DB10984Peppermint2 / 3Completed1
DB11195Xylitol2 / 3Completed2
DB01060Amoxicillin3Completed2
DB01416Cefpodoxime3Recruiting1
DB00766Clavulanic acid3Completed1
DB09551Desoxyribonuclease3Withdrawn1
DB00003Dornase alfa3Withdrawn1
DB01137Levofloxacin3Completed2
DB14512Mometasone furoate3Recruiting1
DB00218Moxifloxacin3Completed1
DB00043Omalizumab3Recruiting1
DB00635Prednisone3Unknown Status1
DB06602Reslizumab3Unknown Status1
DB00316Acetaminophen4Completed1
DB00918Almotriptan4Completed1
DB01060Amoxicillin4Completed4
DB01060Amoxicillin4Terminated1
DB01060Amoxicillin4Unknown Status1
DB00207Azithromycin4Completed2
DB00766Clavulanic acid4Completed4
DB00766Clavulanic acid4Terminated1
DB00766Clavulanic acid4Unknown Status1
DB00254Doxycycline4Completed1
DB01050Ibuprofen4Completed1
DB00764Mometasone4Completed1
DB14512Mometasone furoate4Completed2
DB00471Montelukast4Completed1
DB00218Moxifloxacin4Terminated1
DB00497Oxycodone4Completed1
DB00852Pseudoephedrine4Completed1
DB00976Telithromycin4Completed1
DB00620Triamcinolone4Completed1