Sinusitis

Also known as: Sinus infection / Sinusitis NOS / Chronic sinusitis

DrugDrug NameDrug Description
DB00316AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DB01060AmoxicillinA penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
DB01114ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB00766Clavulanic acidA beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
DB15881ClonazolineNot Annotated
DB09357DexpanthenolAn alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
DB08801DimetindeneIndicated as symptomatic treatment of allergic reactions: urticaria, allergies of the upper respiratory tract such as hey fever and perennial rhinitis, food and drug allergies; pruritus of various origins, except...
DB00764MometasoneA corticosteroid with no indications.
DB00218MoxifloxacinA fluoroquinolone antibiotic used to treat various bacterial infections.
DB06711NaphazolineA sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion.
DB00788NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
DB13216OxolamineOxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant . It is listed as a prescription drug in New Zealand legislation ....
DB00388PhenylephrineAn alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics.
DB09209PholcodinePholcodine is indicated as a cough suppressant for the temporary relief of non-productive dry cough. It is stated to present a required label indication of "temporary relief of dry cough."...
DB00852PseudoephedrineAn alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.
DB09153Sodium chlorideAn ingredient found in a variety of nutritional products as a source of electrolytes and water.
DB06764TetryzolineAn alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations.
DB06694XylometazolineA direct acting sympathomimetic agent used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds.
DrugDrug NameTargetType
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenP-glycoprotein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin E synthase 3target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenSerum albumincarrier
DB00316AcetaminophenFatty-acid amide hydrolase 1enzyme
DB00316AcetaminophenGlutathione S-transferase Penzyme
DB00316AcetaminophenGlutathione S-transferase Mu 1enzyme
DB01060AmoxicillinSolute carrier family 15 member 1transporter
DB01060AmoxicillinSolute carrier family 15 member 2transporter
DB01060AmoxicillinSolute carrier family 22 member 6transporter
DB01060AmoxicillinCytochrome P450 2C8enzyme
DB01060AmoxicillinSerum albumincarrier
DB01060AmoxicillinBeta-lactamase 2enzyme
DB01060AmoxicillinPenicillin binding proteintarget
DB01114ChlorpheniramineHistamine H1 receptortarget
DB01114ChlorpheniramineCytochrome P450 3A4enzyme
DB01114ChlorpheniramineCytochrome P450 2D6enzyme
DB01114ChlorpheniramineSodium-dependent serotonin transportertarget
DB01114ChlorpheniramineSodium-dependent noradrenaline transportertarget
DB01114ChlorpheniramineSodium-dependent dopamine transportertarget
DB01114ChlorpheniramineCytochrome P450 3A5enzyme
DB01114ChlorpheniramineCytochrome P450 3A7enzyme
DB01114ChlorpheniramineSolute carrier family 22 member 2transporter
DB01114ChlorpheniramineSolute carrier family 22 member 1transporter
DB00766Clavulanic acidBacterial beta-lactamase enzymesenzyme
DB00766Clavulanic acidBacterial beta-lactamase enzymestarget
DB00766Clavulanic acidSodium/glucose cotransporter 1transporter
DB08801DimetindeneMuscarinic acetylcholine receptor M2target
DB08801DimetindeneHistamine H1 receptortarget
DB00764MometasoneGlucocorticoid receptortarget
DB00764MometasoneCytochrome P450 2C8enzyme
DB00764MometasoneProgesterone receptortarget
DB00764MometasoneCytochrome P450 3A4enzyme
DB00764MometasoneCytochrome P450 3A5enzyme
DB00218MoxifloxacinDNA gyrase subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 4 subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 2-alphatarget
DB00218MoxifloxacinCytochrome P450 1A2enzyme
DB06711NaphazolineAlpha-1A adrenergic receptortarget
DB06711NaphazolineAlpha-2A adrenergic receptortarget
DB00788NaproxenProstaglandin G/H synthase 1target
DB00788NaproxenProstaglandin G/H synthase 2target
DB00788NaproxenSerum albumincarrier
DB00788NaproxenCytochrome P450 2C9enzyme
DB00788NaproxenCytochrome P450 1A2enzyme
DB00788NaproxenSolute carrier organic anion transporter family member 1A2transporter
DB00788NaproxenSolute carrier family 22 member 6transporter
DB00788NaproxenCytochrome P450 2C8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 2B7enzyme
DB00788NaproxenPeptostreptococcal albumin-binding proteintarget
DB00788NaproxenBile salt export pumptransporter
DB00788NaproxenP-glycoprotein 1transporter
DB00788NaproxenUDP-glucuronosyltransferase 1-3enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-6enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-7enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-9enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-10enzyme
DB00788NaproxenSolute carrier family 22 member 8transporter
DB00388PhenylephrineAlpha-1A adrenergic receptortarget
DB00388PhenylephrineAlpha-1B adrenergic receptortarget
DB00388PhenylephrineAmine oxidase [flavin-containing] Aenzyme
DB00388PhenylephrineAlpha-1D adrenergic receptortarget
DB00388PhenylephrineCytochrome P450 1A2enzyme
DB00388PhenylephrineSulfotransferase 1A3/1A4enzyme
DB00388PhenylephrineAmine oxidase [flavin-containing] Benzyme
DB09209PholcodineMu-type opioid receptortarget
DB09209PholcodineKappa-type opioid receptortarget
DB09209PholcodineDelta-type opioid receptortarget
DB00852PseudoephedrineAlpha-1A adrenergic receptortarget
DB00852PseudoephedrineAlpha-2A adrenergic receptortarget
DB00852PseudoephedrineBeta-2 adrenergic receptortarget
DB00852PseudoephedrineAmine oxidase [flavin-containing] Aenzyme
DB00852PseudoephedrineBeta-1 adrenergic receptortarget
DB00852PseudoephedrineSodium-dependent dopamine transportertarget
DB00852PseudoephedrineSodium-dependent noradrenaline transportertarget
DB00852PseudoephedrineSodium-dependent serotonin transportertarget
DB00852PseudoephedrineNuclear factor of activated T-cells, cytoplasmic 1target
DB00852PseudoephedrineTumor necrosis factortarget
DB00852PseudoephedrineNuclear factor NF-kappa-B p105 subunittarget
DB00852Pseudoephedrineactivator protein 1target
DB00852PseudoephedrineInterleukin-2target
DB00852PseudoephedrineSerum albumincarrier
DB00852PseudoephedrineSodium-dependent noradrenaline transportertransporter
DB00852PseudoephedrineSodium-dependent dopamine transportertransporter
DB00852PseudoephedrineSodium-dependent serotonin transportertransporter
DB06764TetryzolineAlpha-1A adrenergic receptortarget
DB06694XylometazolineAlpha-2A adrenergic receptortarget
DB06694XylometazolineAlpha-1A adrenergic receptortarget
DB06694XylometazolineAlpha-1B adrenergic receptortarget
DB06694XylometazolineAlpha-1D adrenergic receptortarget
DB06694XylometazolineAlpha-2B adrenergic receptortarget
DB06694XylometazolineAlpha-2C adrenergic receptortarget
DrugDrug NamePhaseStatusCount
DB01167Itraconazole1Completed1
DB00661Verapamil1Terminated1
DB00468Quinine1 / 2Terminated1
DB00207Azithromycin2Completed1
DB00394Beclomethasone dipropionate2Withdrawn1
DB01222Budesonide2Withdrawn1
DB01112Cefuroxime2Withdrawn1
DB00003Dornase alfa2Completed1
DB00874Guaifenesin2Withdrawn1
DB00852Pseudoephedrine2Withdrawn1
DB01222Budesonide2 / 3Completed1
DB00959Methylprednisolone2 / 3Completed1
DB11195Xylitol2 / 3Recruiting1
DB01060Amoxicillin3Completed1
DB01060Amoxicillin3Recruiting1
DB01416Cefpodoxime3Recruiting1
DB00766Clavulanic acid3Recruiting1
DB09551Desoxyribonuclease3Withdrawn1
DB00003Dornase alfa3Withdrawn1
DB01137Levofloxacin3Completed2
DB00218Moxifloxacin3Completed1
DB00635Prednisone3Unknown Status1
DB06602Reslizumab3Unknown Status1
DB00316Acetaminophen4Recruiting1
DB00918Almotriptan4Completed1
DB01060Amoxicillin4Completed4
DB01060Amoxicillin4Terminated1
DB01060Amoxicillin4Unknown Status1
DB00207Azithromycin4Completed2
DB00766Clavulanic acid4Completed4
DB00766Clavulanic acid4Terminated1
DB00766Clavulanic acid4Unknown Status1
DB00254Doxycycline4Completed1
DB01050Ibuprofen4Recruiting1
DB00764Mometasone4Completed1
DB14512Mometasone furoate4Completed2
DB00471Montelukast4Completed1
DB00218Moxifloxacin4Terminated1
DB00497Oxycodone4Recruiting1
DB00852Pseudoephedrine4Completed1
DB00976Telithromycin4Completed1
DB00620Triamcinolone4Completed1
DB01060AmoxicillinNot AvailableCompleted5
DB00207AzithromycinNot AvailableCompleted2
DB00626BacitracinNot AvailableWithdrawn1
DB01222BudesonideNot AvailableCompleted1
DB00341CetirizineNot AvailableCompleted1
DB00766Clavulanic acidNot AvailableCompleted5
DB00588Fluticasone propionateNot AvailableCompleted1
DB00635PrednisoneNot AvailableCompleted1
DB00852PseudoephedrineNot AvailableCompleted2
DB01015SulfamethoxazoleNot AvailableCompleted1
DB00440TrimethoprimNot AvailableCompleted1
DB00661VerapamilNot AvailableTerminated1
DB00558ZanamivirNot AvailableCompleted1