Osteoporosis

Also known as: Involutional osteoporosis without current pathological fracture / Osteoporosis, unspecified / Osteoporosis NOS

DrugDrug NameDrug Description
DB00630Alendronic acidA bisphosphonate drug that prevents osteoclastic bone resorption and is used for the prevention and treatment of osteoporosis.
DB11093Calcium citrateAn ingredient found in a variety of supplements and vitamins.
DB00286Conjugated estrogensA mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis.
DB00710IbandronateA bisphosphonate used to treat osteoporosis in postmenopausal women.
DB00481RaloxifeneA selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women.
DB00884Risedronic acidA bisphosphonate used to treat osteoporosis and Paget's disease.
DB11866RomosozumabA monoclonal antibody used to treat osteoporosis in postmenopausal women at high risk of fracture, patients who are intolerant of other treatments, or patients who have failed other treatments.
DB00017Salmon calcitoninA synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
DB06285TeriparatideA recombinant parathyroid hormone used for the treatment of osteoporosis.
DB00399Zoledronic acidA bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors.
DrugDrug NameTargetType
DB00630Alendronic acidFarnesyl pyrophosphate synthasetarget
DB00630Alendronic acidTyrosine-protein phosphatase non-receptor type 4target
DB00630Alendronic acidReceptor-type tyrosine-protein phosphatase Starget
DB00630Alendronic acidReceptor-type tyrosine-protein phosphatase epsilontarget
DB00630Alendronic acidV-type proton ATPase catalytic subunit Atarget
DB00630Alendronic acidHydroxylapatitetarget
DB11093Calcium citrateTransient receptor potential cation channel subfamily V member 6transporter
DB11093Calcium citrateCalbindincarrier
DB11093Calcium citrateProtein S100-Gcarrier
DB11093Calcium citrateSodium/calcium exchanger 1transporter
DB11093Calcium citrateTransient receptor potential cation channel subfamily V member 5transporter
DB11093Calcium citrateExtracellular calcium-sensing receptortarget
DB11093Calcium citrateCalreticulintarget
DB11093Calcium citrateCalcium and integrin-binding protein 1target
DB11093Calcium citrateProgrammed cell death protein 6target
DB11093Calcium citrateSorcintarget
DB11093Calcium citrateCalcineurin B homologous protein 1target
DB11093Calcium citrateSPARCtarget
DB11093Calcium citrateCalnexintarget
DB11093Calcium citrateFibrillin-2target
DB11093Calcium citrateProtein S100-Btarget
DB11093Calcium citrateCalsequestrin-2target
DB11093Calcium citrateRegucalcintarget
DB11093Calcium citratePeflintarget
DB11093Calcium citrateProtein S100-A6target
DB11093Calcium citrateTranslationally-controlled tumor proteintarget
DB11093Calcium citrateCalcium and integrin-binding family member 2target
DB11093Calcium citrateProtein S100-A13target
DB11093Calcium citrateCalsequestrin-1target
DB11093Calcium citrateNucleobindin-1target
DB11093Calcium citrateNucleobindin-2target
DB11093Calcium citrateCalmodulintarget
DB11093Calcium citrateFibrillin-3target
DB11093Calcium citrateGrancalcintarget
DB11093Calcium citrateCalcium-dependent secretion activator 1target
DB11093Calcium citrateSerum albumincarrier
DB11093Calcium citrateCalmodulin-2target
DB11093Calcium citrateCalmodulin-3target
DB11093Calcium citrateProtein S100-A16target
DB11093Calcium citrateCalretinintarget
DB11093Calcium citrateCalcyphosintarget
DB11093Calcium citrateCalcium-dependent secretion activator 2target
DB11093Calcium citrateCalreticulin-3target
DB11093Calcium citrateRyanodine receptor 1transporter
DB11093Calcium citrateRyanodine receptor 2transporter
DB11093Calcium citratePolycystic kidney disease 2-like 1 proteintransporter
DB11093Calcium citrateNeurexin-1target
DB11093Calcium citrateNeuronal calcium sensor 1target
DB11093Calcium citrateRyanodine receptor 3transporter
DB11093Calcium citratePolycystic kidney disease protein 1-like 3transporter
DB11093Calcium citrateCation channel sperm-associated protein 1transporter
DB11093Calcium citrateVoltage-dependent L-type calcium channeltransporter
DB11093Calcium citrateVoltage-dependent P/Q-type calcium channeltransporter
DB11093Calcium citrateVoltage-dependent T-type calcium channeltransporter
DB11093Calcium citrateVoltage-dependent R-type calcium channeltransporter
DB00286Conjugated estrogensEstrogen receptor alphatarget
DB00286Conjugated estrogensCytochrome P450 3A4enzyme
DB00286Conjugated estrogensCytochrome P450 1A2enzyme
DB00286Conjugated estrogensCatechol O-methyltransferaseenzyme
DB00286Conjugated estrogensCanalicular multispecific organic anion transporter 2transporter
DB00286Conjugated estrogensMultidrug resistance-associated protein 4transporter
DB00286Conjugated estrogensMultidrug resistance-associated protein 1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1A2transporter
DB00286Conjugated estrogensSodium/bile acid cotransportertransporter
DB00286Conjugated estrogensSolute carrier family 22 member 10transporter
DB00286Conjugated estrogensSolute carrier family 22 member 8transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1C1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1B1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 2B1transporter
DB00286Conjugated estrogensP-glycoprotein 1transporter
DB00286Conjugated estrogensSolute carrier family 22 member 6transporter
DB00286Conjugated estrogensOrganic solute transporter subunit alphatransporter
DB00286Conjugated estrogensOrganic solute transporter subunit betatransporter
DB00286Conjugated estrogensCanalicular multispecific organic anion transporter 1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 4A1transporter
DB00286Conjugated estrogensATP-binding cassette sub-family C member 11transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1B3transporter
DB00286Conjugated estrogensSolute carrier family 22 member 11transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 3A1transporter
DB00286Conjugated estrogensATP-binding cassette sub-family G member 2transporter
DB00286Conjugated estrogensThyroxine-binding globulincarrier
DB00286Conjugated estrogensSex hormone-binding globulincarrier
DB00286Conjugated estrogensSerum albumincarrier
DB00286Conjugated estrogensEstrogen receptor betatarget
DB00710IbandronateFarnesyl pyrophosphate synthasetarget
DB00710IbandronateHydroxylapatitetarget
DB00710IbandronateGeranylgeranyl pyrophosphate synthasetarget
DB00481RaloxifeneEstrogen receptor alphatarget
DB00481RaloxifeneEstrogen receptor betatarget
DB00481RaloxifeneAldehyde oxidaseenzyme
DB00481RaloxifeneCytochrome P450 2C8enzyme
DB00481RaloxifeneCytochrome P450 2B6enzyme
DB00481RaloxifeneCytochrome P450 19A1enzyme
DB00481RaloxifeneCytochrome P450 3A4enzyme
DB00481RaloxifeneSerpin B9target
DB00481RaloxifeneTrefoil factor 1target
DB00481RaloxifeneUDP-glucuronosyltransferase 1-1enzyme
DB00481RaloxifeneSerum albumincarrier
DB00481RaloxifeneAlpha-1-acid glycoprotein 1carrier
DB00481RaloxifeneSolute carrier organic anion transporter family member 1B1transporter
DB00481RaloxifeneSolute carrier organic anion transporter family member 1B3transporter
DB00481RaloxifeneP-glycoprotein 1transporter
DB00481RaloxifeneATP-binding cassette sub-family G member 2transporter
DB00481RaloxifeneCanalicular multispecific organic anion transporter 1transporter
DB00481RaloxifeneCanalicular multispecific organic anion transporter 2transporter
DB00481RaloxifeneMultidrug resistance-associated protein 4transporter
DB00481RaloxifeneUDP-glucuronosyltransferase 1-10enzyme
DB00481RaloxifeneUDP-glucuronosyltransferase 1-8enzyme
DB00884Risedronic acidFarnesyl pyrophosphate synthasetarget
DB00884Risedronic acidHydroxylapatitetarget
DB00884Risedronic acidProstaglandin G/H synthase 2enzyme
DB11866RomosozumabSclerostintarget
DB00017Salmon calcitoninCalcitonin receptortarget
DB06285TeriparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
DB00399Zoledronic acidFarnesyl pyrophosphate synthasetarget
DB00399Zoledronic acidGeranylgeranyl pyrophosphate synthasetarget
DB00399Zoledronic acidHydroxylapatitetarget
DB00399Zoledronic acidMultidrug resistance-associated protein 1transporter
DrugDrug NamePhaseStatusCount
DB01164Calcium chloride0Completed1
DB11126Calcium gluconate0Completed1
DB00798Gentamicin0Completed1
DB00760Meropenem0Completed1
DB05829Parathyroid hormone0Completed2
DB00512Vancomycin0Completed1
DB00630Alendronic acid1Active Not Recruiting1
DB00630Alendronic acid1Completed5
DB06401Bazedoxifene1Completed2
DB00136Calcitriol1Completed1
DB00169Cholecalciferol1Completed5
DB06643Denosumab1Completed2
DB06643Denosumab1Terminated1
DB05295Eldecalcitol1Recruiting1
DB00005Etanercept1Terminated1
DB01026Ketoconazole1Completed1
DB14513Magnesium1Completed1
DB06548Minodronic acid1Completed2
DB06670Odanacatib1Completed5
DB06670Odanacatib1Terminated1
DB05829Parathyroid hormone1Completed2
DB05829Parathyroid hormone1Withdrawn2
DB00481Raloxifene1Completed2
DB00884Risedronic acid1Completed3
DB11866Romosozumab1Completed2
DB05255Ronacaleret1Completed1
DB06285Teriparatide1Completed1
DB06285Teriparatide1Unknown Status1
DB06285Teriparatide1Withdrawn1
DB11094Vitamin D1Completed2
DB12276Apomine1 / 2Terminated1
DB06643Denosumab1 / 2Withdrawn1
DB14307Green tea leaf1 / 2Completed1
DB00282Pamidronic acid1 / 2Terminated1
DB05084Abaloparatide2Completed1
DB00630Alendronic acid2Active Not Recruiting1
DB00630Alendronic acid2Completed8
DB00630Alendronic acid2Recruiting1
DB00630Alendronic acid2Suspended1
DB00630Alendronic acid2Terminated1
DB00630Alendronic acid2Unknown Status1
DB01436Alfacalcidol2Recruiting1
DB01217Anastrozole2Completed1
DB06249Arzoxifene2Completed1
DB12239Balicatib2Completed2
DB06401Bazedoxifene2Recruiting1
DB12560Blosozumab2Completed1
DB01373Calcium2Active Not Recruiting1
DB01373Calcium2Completed4
DB01373Calcium2Recruiting2
DB11348Calcium Phosphate2Completed1
DB06724Calcium carbonate2Completed2
DB00169Cholecalciferol2Completed1
DB00169Cholecalciferol2Recruiting1
DB06643Denosumab2Completed5
DB06643Denosumab2Recruiting2
DB06643Denosumab2Terminated1
DB06643Denosumab2Withdrawn1
DB11639Dibotermin alfa2Completed1
DB00153Ergocalciferol2Completed1
DB00153Ergocalciferol2Recruiting1
DB00783Estradiol2Completed1
DB00783Estradiol2Terminated1
DB00977Ethinylestradiol2Completed1
DB01645Genistein2Completed1
DB00710Ibandronate2Recruiting1
DB06202Lasofoxifene2Completed1
DB01006Letrozole2Completed1
DB00367Levonorgestrel2Completed1
DB11620Neridronic Acid2Completed1
DB00957Norgestimate2Completed1
DB06670Odanacatib2Completed2
DB00282Pamidronic acid2Recruiting1
DB05829Parathyroid hormone2Completed5
DB05255Ronacaleret2Terminated1
DB01098Rosuvastatin2Recruiting1
DB00017Salmon calcitonin2Completed1
DB14778Setrusumab2Completed1
DB00641Simvastatin2Recruiting1
DB00052Somatotropin2Completed1
DB05732Strontium malonate2Completed1
DB06285Teriparatide2Completed12
DB06285Teriparatide2Recruiting2
DB06285Teriparatide2Terminated1
DB06285Teriparatide2Unknown Status2
DB06285Teriparatide2Withdrawn1
DB00624Testosterone2Completed1
DB00624Testosterone2Suspended1
DB00624Testosterone2Unknown Status1
DB11094Vitamin D2Active Not Recruiting1
DB11094Vitamin D2Completed3
DB11094Vitamin D2Recruiting3
DB00399Zoledronic acid2Completed6
DB00399Zoledronic acid2Recruiting2
DB00399Zoledronic acid2Unknown Status1
DB00399Zoledronic acid2Withdrawn1
DB00630Alendronic acid2 / 3Unknown Status1
DB00710Ibandronate2 / 3Completed1
DB06548Minodronic acid2 / 3Completed1
DB05829Parathyroid hormone2 / 3Completed1
DB05581Teriparatide2 / 3Completed1
DB06285Teriparatide2 / 3Completed1
DB00399Zoledronic acid2 / 3Terminated1
DB05084Abaloparatide3Active Not Recruiting2
DB05084Abaloparatide3Completed1
DB00630Alendronic acid3Completed18
DB00630Alendronic acid3Terminated4
DB00630Alendronic acid3Unknown Status2
DB00630Alendronic acid3Withdrawn1
DB01436Alfacalcidol3Completed1
DB06401Bazedoxifene3Completed6
DB00136Calcitriol3Completed1
DB01373Calcium3Completed8
DB01373Calcium3Unknown Status1
DB06724Calcium carbonate3Completed4
DB11093Calcium citrate3Completed1
DB11126Calcium gluconate3Active Not Recruiting1
DB11126Calcium gluconate3Completed1
DB00169Cholecalciferol3Completed7
DB00169Cholecalciferol3Unknown Status1
DB00286Conjugated estrogens3Completed3
DB06643Denosumab3Active Not Recruiting1
DB06643Denosumab3Completed11
DB06643Denosumab3Recruiting1
DB06643Denosumab3Terminated1
DB05295Eldecalcitol3Completed1
DB00783Estradiol3Completed4
DB00783Estradiol3Recruiting1
DB00783Estradiol3Terminated1
DB00014Goserelin3Recruiting1
DB00710Ibandronate3Completed1
DB06202Lasofoxifene3Completed2
DB01006Letrozole3Completed3
DB00603Medroxyprogesterone acetate3Completed3
DB14049Nitrate3Completed1
DB00727Nitroglycerin3Completed3
DB06670Odanacatib3Completed2
DB06670Odanacatib3Terminated1
DB06670Odanacatib3Withdrawn1
DB05829Parathyroid hormone3Completed6
DB01022Phylloquinone3Completed1
DB09528Phylloquinone3Completed1
DB00396Progesterone3Completed1
DB00481Raloxifene3Completed2
DB00884Risedronic acid3Completed11
DB00884Risedronic acid3Withdrawn1
DB00017Salmon calcitonin3Completed2
DB00052Somatotropin3Unknown Status1
DB06285Teriparatide3Completed13
DB09070Tibolone3Completed1
DB00539Toremifene3Completed1
DB11094Vitamin D3Completed7
DB11094Vitamin D3Unknown Status2
DB00399Zoledronic acid3Active Not Recruiting1
DB00399Zoledronic acid3Completed17
DB00399Zoledronic acid3Terminated2
DB05084Abaloparatide4Recruiting1
DB00316Acetaminophen4Completed1
DB00630Alendronic acid4Completed14
DB00630Alendronic acid4Recruiting1
DB00630Alendronic acid4Unknown Status2
DB01436Alfacalcidol4Unknown Status1
DB01076Atorvastatin4Completed1
DB01222Budesonide4Withdrawn1
DB00136Calcitriol4Unknown Status1
DB01373Calcium4Completed1
DB01373Calcium4Unknown Status1
DB00169Cholecalciferol4Completed3
DB00169Cholecalciferol4Unknown Status1
DB01012Cinacalcet4Completed1
DB01013Clobetasol propionate4Not Yet Recruiting1
DB00618Demeclocycline4Completed1
DB06643Denosumab4Active Not Recruiting1
DB06643Denosumab4Completed3
DB06643Denosumab4Recruiting6
DB06643Denosumab4Unknown Status1
DB00879Emtricitabine4Active Not Recruiting1
DB00153Ergocalciferol4Completed1
DB00736Esomeprazole4Completed1
DB00783Estradiol4Completed1
DB00783Estradiol4Unknown Status1
DB13956Estradiol valerate4Completed1
DB01077Etidronic acid4Completed1
DB12625Evogliptin4Unknown Status1
DB01095Fluvastatin4Completed1
DB01120Gliclazide4Completed1
DB00710Ibandronate4Completed4
DB00710Ibandronate4Terminated1
DB00451Levothyroxine4Completed1
DB08882Linagliptin4Unknown Status1
DB06655Liraglutide4Completed1
DB14936Menaquinone 64Completed1
DB12148Menatetrenone4Completed1
DB00338Omeprazole4Completed1
DB00282Pamidronic acid4Completed1
DB05829Parathyroid hormone4Completed1
DB01132Pioglitazone4Unknown Status1
DB00396Progesterone4Completed1
DB00396Progesterone4Unknown Status1
DB00481Raloxifene4Completed5
DB00481Raloxifene4Recruiting1
DB06817Raltegravir4Completed1
DB00884Risedronic acid4Completed9
DB00884Risedronic acid4Terminated2
DB09267Strontium ranelate4Completed2
DB09299Tenofovir alafenamide4Active Not Recruiting1
DB00300Tenofovir disoproxil4Active Not Recruiting1
DB06285Teriparatide4Completed12
DB06285Teriparatide4Recruiting1
DB06285Teriparatide4Terminated1
DB06285Teriparatide4Unknown Status1
DB00624Testosterone4Completed1
DB00759Tetracycline4Completed1
DB09070Tibolone4Completed1
DB00177Valsartan4Completed1
DB04876Vildagliptin4Completed1
DB11094Vitamin D4Completed4
DB00399Zoledronic acid4Active Not Recruiting1
DB00399Zoledronic acid4Completed5
DB00399Zoledronic acid4Recruiting3
DB00630Alendronic acidNot AvailableCompleted8
DB00630Alendronic acidNot AvailableTerminated2
DB01436AlfacalcidolNot AvailableUnknown Status1
DB00125ArginineNot AvailableCompleted1
DB01076AtorvastatinNot AvailableCompleted1
DB06401BazedoxifeneNot AvailableCompleted2
DB01128BicalutamideNot AvailableCompleted1
DB01373CalciumNot AvailableCompleted2
DB06724Calcium carbonateNot AvailableCompleted2
DB00564CarbamazepineNot AvailableCompleted1
DB00169CholecalciferolNot AvailableCompleted4
DB00720Clodronic acidNot AvailableCompleted1
DB00286Conjugated estrogensNot AvailableUnknown Status1
DB01262DecitabineNot AvailableCompleted1
DB08826DeferiproneNot AvailableCompleted1
DB00746DeferoxamineNot AvailableCompleted1
DB06643DenosumabNot AvailableActive Not Recruiting1
DB06643DenosumabNot AvailableCompleted1
DB06643DenosumabNot AvailableRecruiting1
DB06643DenosumabNot AvailableUnknown Status1
DB05295EldecalcitolNot AvailableUnknown Status1
DB00153ErgocalciferolNot AvailableCompleted1
DB00783EstradiolNot AvailableCompleted1
DB01077Etidronic acidNot AvailableCompleted1
DB00014GoserelinNot AvailableCompleted1
DB00710IbandronateNot AvailableCompleted4
DB01050IbuprofenNot AvailableCompleted1
DB04465LactoseNot AvailableCompleted1
DB01006LetrozoleNot AvailableCompleted1
DB01277MecaserminNot AvailableCompleted1
DB01065MelatoninNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB00282Pamidronic acidNot AvailableCompleted1
DB05829Parathyroid hormoneNot AvailableCompleted2
DB01022PhylloquinoneNot AvailableCompleted1
DB09528PhylloquinoneNot AvailableCompleted1
DB00635PrednisoneNot AvailableTerminated1
DB00396ProgesteroneNot AvailableUnknown Status1
DB00481RaloxifeneNot AvailableCompleted3
DB00884Risedronic acidNot AvailableCompleted6
DB00203SildenafilNot AvailableCompleted1
DB00052SomatotropinNot AvailableCompleted1
DB14227Technetium Tc-99mNot AvailableCompleted1
DB06285TeriparatideNot AvailableActive Not Recruiting1
DB06285TeriparatideNot AvailableCompleted6
DB06285TeriparatideNot AvailableRecruiting2
DB06285TeriparatideNot AvailableUnknown Status2
DB06285TeriparatideNot AvailableWithdrawn1
DB13946Testosterone undecanoateNot AvailableCompleted1
DB00273TopiramateNot AvailableCompleted1
DB00313Valproic acidNot AvailableCompleted1
DB11094Vitamin DNot AvailableCompleted4
DB00399Zoledronic acidNot AvailableCompleted7
DB00399Zoledronic acidNot AvailableUnknown Status1