Reaction: Phenytoin arene-oxide to 1 product

dihydroxylation; oxidationMetabolism of Phenytoin

Phenytoin arene-oxide is converted to Phenytoin dihydrodiol by Cytochrome P450 1A2, Cytochrome P450 2A6, Cytochrome P450 2C19 and 6 other enzymes.

Direction

What you can answer from here — as of December 18, 2019

9EnzymesEach linked to its target card
Listed above
1ReferenceThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 1A2, Cytochrome P450 2A6, and Cytochrome P450 2C19, and which of those pairings are clinically significant?

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