Reaction: Imatinib to 1 product

N-demethylationMajor circulating metaboliteMetabolism of Imatinib

Imatinib is converted to N-Desmethylimatinib by Cytochrome P450 2C9, Cytochrome P450 3A5, Cytochrome P450 2D6 and 5 other enzymes.

Direction
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active

What you can answer from here — as of June 22, 2022

8EnzymesEach linked to its target card
Listed above
3ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 2C9, Cytochrome P450 3A5, and Cytochrome P450 2D6, and which of those pairings are clinically significant?

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