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Displaying results 91 - 100 of 100 in total
  1. Target

    Kynurenine--oxoglutarate transaminase 3

    go.drugbank.com/bio_entities/BE0002162
    TargetHumans

    Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro).

  2. Target

    Cyanocobalamin reductase / alkylcobalamin dealkylase

    go.drugbank.com/bio_entities/BE0002175
    TargetHumans

    The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute … to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine (PubMed:21071249, PubMed:27771510).

  3. Target

    o-succinylbenzoate synthase

    go.drugbank.com/bio_entities/BE0002715
    TargetEscherichia coli (strain K12)

    Does not show detectable N-acylamino acid racemase (NAAAR) activity with N-acetyl-S-methionine as substrate (PubMed:10194342).

  4. Target

    N-succinylamino acid racemase

    go.drugbank.com/bio_entities/BE0003211
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Can catalyze the racemization of a broad range of N-acylamino acids, including N-acetyl-D/L-methionine, N-acetyl-D/L-phenylalanine, N-acetyl-L-glutamine, N-acetyl-L-tryptophan, N-acetyl-L-leucine, N-formyl-D-methionine … , N-formyl-D-norleucine, N-carbamoyl-D-methionine and N-carbamoyl-D-norleucine (PubMed:15313614, PubMed:16650857, PubMed:25875730).

  5. Target

    Peptide deformylase

    go.drugbank.com/bio_entities/BE0003877
    TargetStreptococcus pyogenes serotype M1

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

  6. Target

    Peptide deformylase

    go.drugbank.com/bio_entities/BE0004268
    TargetMycobacterium tuberculosis

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).

  7. Target

    Squalene epoxidase ERG1

    go.drugbank.com/bio_entities/BE0004670
    TargetYeast

    Then, the sterol 24-C-methyltransferase ERG6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

  8. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0009225
    TargetPlasmodium falciparum (isolate 3D7)

    Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via

  9. Target

    Histone-lysine N-methyltransferase 2A

    go.drugbank.com/bio_entities/BE0010441
    TargetHumans

    Catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism.

  10. Target

    N-formyl peptide receptor 2

    go.drugbank.com/bio_entities/BE0012843
    TargetHumans

    Pattern recognition G protein-coupled receptor (GPCR) that recognizes peptides with N-terminal formyl methionine, which are derived from invading pathogens or host mitochondria as pathogen or damage-associated