Search

Displaying results 91 - 100 of 225 in total
  1. Target

    Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

    go.drugbank.com/bio_entities/BE0018277
    TargetHumans

    Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). … Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity)

    Polypeptides: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1Synonyms: Leucine-rich repeat and immunoglobulin domain-containing protein 1
  2. Target

    Bacterial hemoglobin

    go.drugbank.com/bio_entities/BE0002903
    TargetVitreoscilla stercoraria

    This protein functions as a terminal oxidase.

    Synonyms: Soluble cytochrome O
  3. Target

    Methylated-DNA--protein-cysteine methyltransferase

    go.drugbank.com/bio_entities/BE0001145
    TargetHumans

    Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.

    Synonyms: 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase
  4. Target

    Lecithin retinol acyltransferase

    go.drugbank.com/bio_entities/BE0000900
    TargetEnzymeHumans

    Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology (By similarity) … converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments (Probable).

    Synonyms: Phosphatidylcholine--retinol O-acyltransferase
  5. Target

    Cystathionine gamma-synthase

    go.drugbank.com/bio_entities/BE0003209
    TargetEnzymeEscherichia coli (strain K12)

    Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. … In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia.

    Synonyms: O-succinylhomoserine (thiol)-lyase
  6. Target

    Threonine-phosphate decarboxylase

    go.drugbank.com/bio_entities/BE0001652
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

    Synonyms: L-threonine-O-3-phosphate decarboxylase
  7. Target

    rRNA methyltransferase 2, mitochondrial

    go.drugbank.com/bio_entities/BE0020789
    TargetHumans

    S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU … This activity may require prior 2'-O-methylguanosine modification at position 1370 (Gm1370) by MRM3 (PubMed:35177605).

    Synonyms: 16S rRNA [Um1369] 2'-O-methyltransferase, 16S rRNA (uridine(1369)-2'-O)-methyltransferaseFunction: rRNA (uridine-2'-O-ribose)-methyltransferase activity
  8. Target

    Cathepsin K

    go.drugbank.com/bio_entities/BE0003417
    TargetHumans

    May play an important role in extracellular matrix degradation. … Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH.

    Synonyms: Cathepsin O
  9. Target

    Lysophosphatidylcholine acyltransferase 1

    go.drugbank.com/bio_entities/BE0017259
    TargetEnzymeHumans

    Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine … Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (By similarity).

    Synonyms: 1-acylglycerol-3-phosphate O-acyltransferase, 1-acylglycerophosphocholine O-acyltransferaseFunction: 1-acylglycerol-3-phosphate O-acyltransferase activity
  10. Target

    Phosphoserine phosphatase

    go.drugbank.com/bio_entities/BE0004590
    TargetHumans

    May also act on O-phospho-D-serine (Probable) … Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine (PubMed:12213811, PubMed:14673469, PubMed:15291819, PubMed

    Synonyms: O-phosphoserine phosphohydrolase