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Cytarabine
go.drugbank.com/drugs/DB00987ApprovedInvestigationalA pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. … Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone, 1-beta-D-Arabinofuranosylcytosinealpha-Tocopherol acetate
go.drugbank.com/drugs/DB14003ApprovedMoreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed [A32451]. … At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use.
Mixtures: TOOTH NOTE Herb Tooth Charcoal Jasmine, TOOTH NOTE Moisturizing Therapy Tooth GRAPEFRUITCategories: Compounds used in a research, industrial, or household setting, Vitamin ELow affinity immunoglobulin gamma Fc region receptor II-a
go.drugbank.com/bio_entities/BE0002098TargetHumansBinds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens
Polypeptides: Low affinity immunoglobulin gamma Fc region receptor II-aSynonyms: FcRII-a, Fc-gamma RII-aTransient receptor potential cation channel subfamily A member 1
go.drugbank.com/bio_entities/BE0001122TargetHumansHas a central role in the pain response to endogenous inflammatory mediators, such as bradykinin and to a diverse array of irritants. … Has a relatively high Ca(2+) selectivity, with a preference for divalent over monovalent cations (Ca(2+) > Ba(2+) > Mg(2+) > NH4(+) > Li(+) > K(+)), the influx of cation into the cytoplasm leads to membrane
Polypeptides: Transient receptor potential cation channel subfamily A member 1Low affinity immunoglobulin gamma Fc region receptor III-A
go.drugbank.com/bio_entities/BE0002097TargetHumansOptimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC
Polypeptides: Low affinity immunoglobulin gamma Fc region receptor III-ASynonyms: IgG Fc receptor III-ASuccinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
go.drugbank.com/bio_entities/BE0002256TargetEnzymeHumans) and produce a new acyl-CoA. … Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate (acetoacetate
Polypeptides: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrialNKG2-A/NKG2-B type II integral membrane protein
go.drugbank.com/bio_entities/BE0010560TargetHumansDominantly counteracts T cell receptor signaling on a subset of memory/effector CD8-positive T cells as part of an antigen-driven response to avoid autoimmunity (PubMed:12387742). … In HLA-E-rich tumor microenvironment, acts as an immune inhibitory checkpoint and may contribute to progressive loss of effector functions of NK cells and tumor-specific T cells, a state known as cell
Polypeptides: NKG2-A/NKG2-B type II integral membrane proteinSynonyms: NK cell receptor A, NKG2-A/B-activating NK receptorZinc sulfate
go.drugbank.com/drugs/DB09322ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".
Mixtures: Zincfrin A, One-A-day Advance Men'sProducts: SULFATO DE ZINC 2MG/ML SOLUCION ORAL SABOR A CEREZA Y SABOR A CHICLE., ZINK AL 25MG BRAUSETABLPatients at High-Risk of a Cardiovascular Event
go.drugbank.com/conditions/DBCOND0163212Drugs: Bempedoic acidSynonyms: Patients at High-Risk of a Cardiovascular EventNot a candidate for curative surgery or radiation
go.drugbank.com/conditions/DBCOND0144324Synonyms: Not a candidate for curative surgery or radiation