Search
Pentobarbital
go.drugbank.com/drugs/DB00312ApprovedVet approvedA short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. … It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration.
Synonyms: 5-Ethyl-5-(1-methyl-butyl)-pyrimidine-2,4,6-trione, 5-ethyl-5-(1-methylbutyl)barbituric acidCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersDihydroergocryptine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126659Drug actionAlpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino ...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortNandrolone decanoate
go.drugbank.com/drugs/DB08804ApprovedIllicitInvestigationalNandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile … [A233789,A233849,L32564,L9464] The process for creating esters of [nandrolone] was patented in Spain in 1959[L33244] and in 1960, it was described as having a long duration of action and strong anabolic
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: PARABOLIN RETARD 5 MG AMPUL, 2 ADET, DECA - DURABOLIN® 50 MGIL15-NK Cell
go.drugbank.com/drugs/DB15725InvestigationalIn particular, incubation with IL-15 allows NK cells to lyse a broad range of fresh and cultured tumor targets that the cell is not normally sensitive to.
Sepetaprost
go.drugbank.com/drugs/DB12043InvestigationalSepetaprost has been used in trials studying the treatment of Open Angle-glaucoma, Ocular Hypertension, and Mild Open Angle-glaucoma (OAG).
Categories: Heterocyclic Compounds, 1-RingErgoloid mesylate Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126658Drug actionErgoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all de...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortThiethylperazine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126476Drug actionThiethylperazine' s antipsychotic effect is due to antagonism at dopamine and serotonin type 2 receptors, with greater activity at serotonin 5-HT2 receptors than at dopamine type-2 receptors.
Drugs: Pyridoxal phosphate · Tyrosine · Sapropterin · Thiethylperazine · Dopamine · Levodopa +2 moreEnzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortAncestim
go.drugbank.com/drugs/DB09103ApprovedWithdrawnIt is a 166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal … Ancestim is a non-glycosylated recombinant methionyl human stem cell factor.
Anileridine
go.drugbank.com/drugs/DB00913ApprovedIllicitWithdrawnAnileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-[2-(4-aminophenyl)ethyl]-4-phenyl-4-piperidinecarboxlic acid ethyl ester, ethyl 1-(2-(4-aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxylateMegestrol acetate Action Pathway
smpdb.ca/view/SMP0126528Drug actionMegestrol acetate is a synthetic progestational hormone initially developed as a contraceptive. Nowadays, it is used as a drug to treat anorexia and cachexia (or unexplained weight loss) and as an antineoplastic agent to treat inoperable...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12