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Tumor necrosis factor receptor superfamily member 16
go.drugbank.com/bio_entities/BE0010540TargetHumansLow affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. … Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF (PubMed:24908487).
Polypeptides: Tumor necrosis factor receptor superfamily member 16Synonyms: NGF receptor, Low affinity neurotrophin receptor p75NTRAntiviral innate immune response receptor RIG-I
go.drugbank.com/bio_entities/BE0012418TargetHumansInnate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leading to the production of type I interferons and pro-inflammatory cytokines (PubMed:15208624
Polypeptides: Antiviral innate immune response receptor RIG-ISynonyms: RIG-I-like receptor 1Tumor necrosis factor receptor superfamily member 13C
go.drugbank.com/bio_entities/BE0018598TargetHumansB-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response
Polypeptides: Tumor necrosis factor receptor superfamily member 13CSynonyms: BAFF receptor, BLyS receptor 3Tumor necrosis factor receptor superfamily member 12A
go.drugbank.com/bio_entities/BE0020009TargetHumansReceptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins
Polypeptides: Tumor necrosis factor receptor superfamily member 12ASynonyms: Tweak-receptorAcetylcholine receptor subunit alpha-type acr-16
go.drugbank.com/bio_entities/BE0027703TargetCaenorhabditis elegansA subunit of the levamisole-insensitive nicotinic receptor.
Polypeptides: Acetylcholine receptor subunit alpha-type acr-16Pyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalPyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
Products: Balmers Cooling Zone 31, Australian Gold Defense Zone Anti-Dandruff Step 2Fenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnIn 2006 and 2009, the FDA issued warnings that it had been detected in diet pills sold online, and imported from foreign manufacturers.
Erlotinib
go.drugbank.com/drugs/DB00530ApprovedInvestigationalRecent studies demonstrate that erlotinib is also a potent inhibitor of JAK2V617F, which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and a substantial proportion … Erlotinib binds to the epidermal growth factor receptor (EGFR) tyrosine kinase in a reversible fashion at the adenosine triphosphate (ATP) binding site of the receptor.
Categories: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitorsCytochrome c oxidase subunit 6A2, mitochondrial
go.drugbank.com/bio_entities/BE0003994TargetHumansElectrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit
Synonyms: COX VIa-M, Cytochrome c oxidase subunit VIA-muscleBiotin
go.drugbank.com/drugs/DB00121ApprovedInvestigationalNutraceuticalA water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Mixtures: Vita-B, Liqui Vita