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Cyanocobalamin reductase / alkylcobalamin dealkylase
go.drugbank.com/bio_entities/BE0002175TargetHumansCobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and NADPH as cosubstrate (PubMed:187795...
Synonyms: Alkylcobalamin:glutathione S-alkyltransferaseRalA-binding protein 1
go.drugbank.com/bio_entities/BE0004770TransporterHumansMultifunctional protein that functions as a downstream effector of RALA and RALB (PubMed:7673236). As a GTPase-activating protein/GAP can inactivate CDC42 and RAC1 by stimulating their GTPase activity (PubMed:7673236). As part of the Ral...
Synonyms: Dinitrophenyl S-glutathione ATPaseFunction: ABC-type glutathione S-conjugate transporter activityEukaryotic peptide chain release factor GTP-binding subunit ERF3A
go.drugbank.com/bio_entities/BE0004448TargetHumansGTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA (PubMed:15987998, PubMed:19417105, PubMed:2511002, PubMed:27863242). GS...
Synonyms: G1 to S phase transition protein 1 homologNitric oxide synthase 1
go.drugbank.com/bio_entities/BE0000067TargetEnzymeHumansProbably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR
Synonyms: Peptidyl-cysteine S-nitrosylase NOS1Cyclopropane mycolic acid synthase MmaA2
go.drugbank.com/bio_entities/BE0002512TargetMycobacterium tuberculosisCatalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.
Synonyms: S-adenosylmethionine-dependent methyltransferaseTransitional endoplasmic reticulum ATPase
go.drugbank.com/bio_entities/BE0004572TargetHumansNecessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to...
Synonyms: HEL-S-70Alcohol dehydrogenase class-3
go.drugbank.com/bio_entities/BE0000009TargetEnzymeHumansAlso acts as a S-nitroso-glutathione reductase by catalyzing the NADH-dependent reduction of S-nitrosoglutathione, thereby regulating protein S-nitrosylation (By similarity) … Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (PubMed:8460164).
Synonyms: S-(hydroxymethyl)glutathione dehydrogenaseBis(monoacylglycero)phosphate synthase CLN5
go.drugbank.com/bio_entities/BE0011971EnzymeHumansCatalyzes the synthesis of bis(monoacylglycero)phosphate (BMP) via transacylation of 2 molecules of lysophosphatidylglycerol (LPG) (PubMed:37708259). BMP also known as lysobisphosphatidic acid plays a key role in the formation of intralu...
Synonyms: S-depalmitoylase CLN5Cytosolic non-specific dipeptidase
go.drugbank.com/bio_entities/BE0018303EnzymeHumansN-[(S)-lactoyl]-L-phenylalanine is an exercise-induced metabolite that influences food intake and systemic energy balance (PubMed:25964343). … Upon physiological conditions of amino acids and lactate excess can also catalyze a reverse proteolysis reaction, generating N-[(S)-lactoyl]-L-phenylalanine and possibly other N-lactoyl-amino acids which
Synonyms: HEL-S-132-Hydroxyacid oxidase 2
go.drugbank.com/bio_entities/BE0004577TargetEnzymeHumansOxidase that catalyzes the oxidation of medium and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, to the corresponding 2-oxoacids (PubMed:10777549). Its role in the oxidation of 2-hydroxy fatty acids may c...
Synonyms: (S)-2-hydroxy-acid oxidase, peroxisomalFunction: (S)-2-hydroxy-acid oxidase activity