Search
Cabergoline Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126670Drug actionactivity on α2B, α2A, and α2C receptors. … It also exhibits: weak agonist activity (in order of decreasing binding affinities) on 5-hydroxytryptamine (5-HT)2B, 5-HT2A, 5-HT1D, dopamine D4, 5-HT1A, dopamine D1, 5-HT1B and 5-HT2C receptors and antagonist
Enzymes: Aromatic-L-amino-acid decarboxylase, D(2) dopamine receptorQuinagolide Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126673Drug actionIt also binds to D1 receptors but with low affinity and little clinical relevance. … It is typically present in the hydrochloride salt form and is marketed as oral tablets.
Enzymes: Aromatic-L-amino-acid decarboxylase, D(2) dopamine receptorRetinol Metabolism
smpdb.ca/view/SMP0000074MetabolicRetinol is part of the vitamin A family, and is known as vitamin A1, and in a dietary context it is a type of preformed vitamin A. … Other forms of vitamin A include retinal, its aldehyde form, retinoic acid, its acid form, and reinyl ester, its ester form.
Chlorpromazine - Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126485Drug actionIV, PO, and rectal (PR) formulations are available. Side effects include dizziness, headache, and extrapyramidal symptoms, including dystonia and tardive dyskinesia. … Chlorpromazine is used for the management of schizophrenia; to control nausea and vomiting; for relief of restlessness and apprehension before surgery; for acute intermittent porphyria; as an adjunct in
Enzymes: Aromatic-L-amino-acid decarboxylase, D(2) dopamine receptorLurasidone Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126526Drug actionLurasidone is an atypical antipsychotic that is a D2 and 5-HT2A (mixed serotonin and dopamine activity) to improve cognition. … Lurasidone is is a benzothiazol derivative and an atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.
Enzymes: Aromatic-L-amino-acid decarboxylase, D(2) dopamine receptorTiapride Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126581Drug actionsymptoms of psychosis, and agitation and aggression in the elderly. … Tiapride is a selective D2 and D3 dopamine receptor blocker indicated for the treatment of a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative
Enzymes: Aromatic-L-amino-acid decarboxylase, D(2) dopamine receptorProchlorperazine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126604Drug actionIt is a phenothiazine derivative, used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. … It depresses the chemoreceptor trigger zone and blocking D2 dopamine receptors in the brain. It was shown to also block histaminergic, cholinergic and noradrenergic receptors.
Drugs: Pyridoxal phosphate · Tyrosine · Sapropterin · Prochlorperazine · Dopamine · Levodopa +2 moreEnzymes: Aromatic-L-amino-acid decarboxylase, D(2) dopamine receptorSafinamide Action Pathway
smpdb.ca/view/SMP0126696Drug actionSafinamide has multiple mechanisms of action and a very high therapeutic index, it binds only the B isoform of MAO but it also inhibits sodium and calcium channels and the glutamate release channels. … The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine.
Enzymes: Aromatic-L-amino-acid decarboxylase, D(2) dopamine receptorClozapine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126963Drug actionAntipsychotic drugs are vital in treating the core symptoms of schizophrenia: hallucinations and delusions As an atypical antipsychotic, clozapine acts an antagonist to both dopamine and serotonin receptors … Clozapine is an antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients. Clozapine is available as oral tablets.
Enzymes: Aromatic-L-amino-acid decarboxylase, D(2) dopamine receptorRemoxipride Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126480Drug actionChronic use upregulates the expression of D2 receptors, while downregulating the expression of D1 and D5 receptors in the prefrontal cortex. … Remoxipride is an atypical antipsychotic dopamine D2 antagonist.
Enzymes: Aromatic-L-amino-acid decarboxylase, D(2) dopamine receptor