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Displaying results 1101 - 1110 of 10000 in total
  1. Target

    U1 small nuclear ribonucleoprotein A

    go.drugbank.com/bio_entities/BE0002708
    TargetHumans

    In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs

    Polypeptides: U1 small nuclear ribonucleoprotein ASynonyms: U1-A, U1 snRNP A
  2. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0003726
    TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  3. Target

    Myocardin-related transcription factor A

    go.drugbank.com/bio_entities/BE0004156
    TargetHumans

    Activity is also regulated by filamentous actin (F-actin) in the nucleus … The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics.

    Polypeptides: Myocardin-related transcription factor ASynonyms: MRTF-A
  4. Target

    Ephrin type-A receptor 5

    go.drugbank.com/bio_entities/BE0005587
    TargetHumans

    Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. … Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5.

    Polypeptides: Ephrin type-A receptor 5
  5. Target

    Ephrin type-A receptor 4

    go.drugbank.com/bio_entities/BE0009438
    TargetHumans

    In addition to its role in axonal guidance plays a role in synaptic plasticity. … In the nervous system, also plays a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation.

    Polypeptides: Ephrin type-A receptor 4
  6. Target

    Acyl-coenzyme A thioesterase 1

    go.drugbank.com/bio_entities/BE0016368
    EnzymeHumans

    Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels.

    Polypeptides: Acyl-coenzyme A thioesterase 1Synonyms: Palmitoyl-coenzyme A thioesterase, Inducible cytosolic acyl-coenzyme A thioester hydrolase
  7. Drug

    Witch hazel

    go.drugbank.com/drugs/DB11111
    ApprovedInvestigationalNutraceutical

    Mixtures: Hemorrhoidal Soothing Well at Walgreens, Preparation HProducts: Placenta EX Deep Line, Tone and Line Change Pack
  8. Drug

    Sulbactam

    go.drugbank.com/drugs/DB09324
    ApprovedInvestigational

    [L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296] … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus.

    Mixtures: AUROPENNZ 1.5 G POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE, PROBICID IV/IM 1 GR FLAKON, 1 ADETCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Protein C

    go.drugbank.com/drugs/DB11312
    ApprovedInvestigational

    Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. … Once in its activated form, APC functions as a serine protease with potent anticoagulant effects, especially in the presence of its cofactor protein S.

    Synonyms: Protein C, Human protein CMixtures: Beriplex P/n 500, Beriplex P/n 1000
  10. Drug

    Granisetron

    go.drugbank.com/drugs/DB00889
    ApprovedInvestigational

    A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: GRANSET 3 MG/3 ML IV İNFÜZYON ÇÖZELTİSİ, AXIGRAN 1MG/ML KON INJ INF