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Displaying results 1151 - 1160 of 10000 in total
  1. Drug

    Furosemide

    go.drugbank.com/drugs/DB00695
    ApprovedInvestigationalVet approved

    Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. … [A182495] The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential.

    Mixtures: SPIRO D TABLINEN 100MG, Lasitace 5 mg/40 mg KapselnSynonyms: 4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid, 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid
  2. Drug

    VM4-037

    go.drugbank.com/drugs/DB15319
    Investigational

    VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037).

  3. Drug

    Parsaclisib

    go.drugbank.com/drugs/DB14867
    Investigational

    Parsaclisib is under investigation in clinical trial NCT03126019 (An Open-Label Study of Parsaclisib in Relapsed or Refractory Follicular Lymphoma (CITADEL-203)).

    Categories: Heterocyclic Compounds, 1-Ring, Phosphatidylinositol-3-kinase (Pi3K) inhibitors
  4. Pathway

    Sarcosinemia

    smpdb.ca/view/SMP0125579
    Disease

    Sarcosine can also be formed in a reversible reaction from S-adenosylmethionine and glycine, using glycine N-methyltransferase as the enzyme, and forming S-adenosylhomocysteine as another product. … This, along with homocysteine, react using betaine-homocysteine S-methyltransferase to form L-methionine, as well as dimethylglycine.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1
  5. Drug

    Pegfilgrastim

    go.drugbank.com/drugs/DB00019
    ApprovedInvestigational

    Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, [filgrastim]. … [A187607] First developed by Amgen, pegfilgrastim was initially approved by the FDA in 2002 and marketed as Neulasta. It is typically administered via a subcutaneous injection.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 吉新芬, PEG-G-CSF
  6. Drug

    DiaPep 277

    go.drugbank.com/drugs/DB06651
    Investigational

    DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460).

    Categories: Group I Chaperonins, Diabetes Mellitus, Type 1
  7. Pathway

    Ritodrine B2-Adrenergic Myometrial Smooth Muscle Relaxation Action Pathway

    smpdb.ca/view/SMP0126043
    Drug action

    Ritodrine is a adrenergic beta agonist used for the treatment and prophylaxis of premature labour. Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adren...

    Drugs: ATP · Ritodrine · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  8. Drug

    Octinoxate

    go.drugbank.com/drugs/DB09496
    ApprovedInvestigational

    It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. … Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage.

    Mixtures: LA Mer The SPF 18 Fluid, LA Mer The SPF 18 Fluid TintCategories: Compounds used in a research, industrial, or household setting
  9. Pathway

    Dimethylglycine Dehydrogenase Deficiency

    smpdb.ca/view/SMP0125578
    Disease

    Dimethylglycine dehydrogenase deficiency, also called DMGDH deficiency and dimethylglycinuria, is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of glycine metabolism caused by a defective DMGDH gene. DMGDH code...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1
  10. Drug

    Bexicaserin

    go.drugbank.com/drugs/DB18885
    Investigational

    Bexicaserin is under investigation in clinical trial NCT05626634 (Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy).

    Synonyms: (7R)-N-(2,2-difluoroethyl)-7-methyl-1,2,3,4,6,7-hexahydro[1,4]diazepino[6,7,1-hi]indole-8-carboxamide