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Acidic amino acid decarboxylase GADL1
go.drugbank.com/bio_entities/BE0002163TargetHumansMay catalyze the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. … Does not exhibit any decarboxylation activity toward glutamate
Polypeptides: Acidic amino acid decarboxylase GADL1Synonyms: Cysteine sulfinic acid decarboxylaseCyclopropane mycolic acid synthase 1
go.drugbank.com/bio_entities/BE0003738TargetMycobacterium tuberculosisCyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence. … Catalyzes the conversion of a double bond to a cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.
Polypeptides: Cyclopropane mycolic acid synthase 1Synonyms: Cyclopropane fatty acid synthase, Mycolic acid methyltransferaseFatty acid-binding protein, liver
go.drugbank.com/bio_entities/BE0003998CarrierTargetHumansBinds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity)
Polypeptides: Fatty acid-binding protein, liverSynonyms: Fatty acid-binding protein 1, Liver-type fatty acid-binding proteinAcid-sensing ion channel 3
go.drugbank.com/bio_entities/BE0004768TargetHumansAs a neuronal acid sensor, probably contributes to mechanoreception, acid nociception, and heat nociception (By similarity). … ASIC3 is more sensitive to protons and gates between closed, open, and desensitized states faster than other ASICs (By similarity).
Polypeptides: Acid-sensing ion channel 3Free fatty acid receptor 3
go.drugbank.com/bio_entities/BE0010132TargetHumansIn omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. … G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis
Polypeptides: Free fatty acid receptor 3Polyunsaturated fatty acid lipoxygenase ALOX12
go.drugbank.com/bio_entities/BE0012732TargetHumansCatalyzes the regio and stereo-specific incorporation of molecular oxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding … An additional function involves a multistep process by which it transforms leukotriene A4/LTA4 into the bioactive lipids lipoxin A4/LXA4 and lipoxin B4/LXB4, both are vasoactive and LXA4 may regulate neutrophil
Polypeptides: Polyunsaturated fatty acid lipoxygenase ALOX12Fatty-acid amide hydrolase 2
go.drugbank.com/bio_entities/BE0015331EnzymeHumansthe sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids
Polypeptides: Fatty-acid amide hydrolase 2Function: fatty acid amide hydrolase activityCationic amino acid transporter 4
go.drugbank.com/bio_entities/BE0000052TargetHumansInvolved in the transport of the cationic amino acids (arginine, lysine and ornithine)
Polypeptides: Cationic amino acid transporter 4Function: basic amino acid transmembrane transporter activityCationic amino acid transporter 3
go.drugbank.com/bio_entities/BE0000136TargetHumansUniporter that mediates the uptake of cationic L-amino acids such as L-arginine, L-lysine and L-ornithine (PubMed:11591158). … The transport is sodium ions- and pH-independent, moderately trans-stimulated and is mediated by passive diffusion (PubMed:11591158)
Polypeptides: Cationic amino acid transporter 3Synonyms: Cationic amino acid transporter y+Acid-sensing ion channel 1
go.drugbank.com/bio_entities/BE0000353TargetTransporterHumansRegulates more or less directly intracellular calcium concentration and CaMKII phosphorylation, and thereby the density of dendritic spines. … Upon extracellular pH drop this channel elicits transient, fast activating, and completely desensitizing inward currents (PubMed:21036899).
Polypeptides: Acid-sensing ion channel 1