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Displaying results 1201 - 1210 of 6949 in total
  1. Target

    Glycine receptor subunit alpha-2

    go.drugbank.com/bio_entities/BE0000745
    TargetHumans

    Subunit of heteromeric glycine-gated chloride channels (PubMed:15302677, PubMed:16144831, PubMed:2155780, PubMed:23895467, PubMed:25445488, PubMed:26370147, PubMed:34473954). Plays a role in synaptic plasticity (By similarity). Contribut...

    Polypeptides: Glycine receptor subunit alpha-2
  2. Target

    Ephrin type-A receptor 2

    go.drugbank.com/bio_entities/BE0000841
    TargetHumans

    The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. … Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

    Polypeptides: Ephrin type-A receptor 2Synonyms: Tyrosine-protein kinase receptor ECK
  3. Target

    Receptor activity-modifying protein 2

    go.drugbank.com/bio_entities/BE0000860
    TargetHumans

    Together with CALCR, act as a receptor complex for calcitonin/CT/CALC (PubMed:35324283). Together with CALCR, also act as a receptor complex for amylin/IAPP (PubMed:35324283) … Accessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed

    Polypeptides: Receptor activity-modifying protein 2Synonyms: Calcitonin-receptor-like receptor activity-modifying protein 2
  4. Target

    Interleukin-3 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0001036
    TargetHumans

    Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted

    Polypeptides: Interleukin-3 receptor subunit alphaSynonyms: IL-3 receptor subunit alpha
  5. Target

    Gastrin/cholecystokinin type B receptor

    go.drugbank.com/bio_entities/BE0001158
    TargetHumans

    Receptor for the peptide hormones gastrin and cholecystokinin (CCK).

    Polypeptides: Gastrin/cholecystokinin type B receptorSynonyms: CCK-B receptor, Cholecystokinin-2 receptor
  6. Target

    Fibroblast growth factor receptor 4

    go.drugbank.com/bio_entities/BE0001203
    TargetHumans

    FGFR4 signaling is down-regulated by receptor internalization and degradation; MMP14 promotes internalization and degradation of FGFR4. … Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of

    Polypeptides: Fibroblast growth factor receptor 4
  7. Target

    Neuropeptide Y receptor type 2

    go.drugbank.com/bio_entities/BE0002419
    TargetHumans

    Receptor activation by ligands also leads to an increase of intracellular Ca(2+) levels (PubMed:7559383, PubMed:7592910). … Receptor for neuropeptide Y (NPY) and peptide YY (PYY) (PubMed:7592910, PubMed:7559383, PubMed:35507650, PubMed:36525977, PubMed:38882210).

    Polypeptides: Neuropeptide Y receptor type 2Synonyms: Y2 receptor, NPY-Y2 receptor
  8. Target

    Atrial natriuretic peptide receptor 3

    go.drugbank.com/bio_entities/BE0002426
    TargetHumans

    May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. … Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP.

    Polypeptides: Atrial natriuretic peptide receptor 3Synonyms: Atrial natriuretic peptide receptor type C, Atrial natriuretic peptide clearance receptor
  9. Target

    Interleukin-6 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0002859
    TargetHumans

    Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal (PubMed:28265003). Signal activation necessitate an association with IL6ST.

    Polypeptides: Interleukin-6 receptor subunit alphaSynonyms: IL-6 receptor subunit alpha
  10. Target

    Signal recognition particle receptor FtsY

    go.drugbank.com/bio_entities/BE0003264
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).

    Polypeptides: Signal recognition particle receptor FtsYSynonyms: SRP receptor