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Displaying results 1221 - 1230 of 8010 in total
  1. Indication

    Lymphomas

    go.drugbank.com/conditions/DBCOND0029770
    Drugs: Betamethasone · Chlorambucil · Cortisone acetate · Cyclophosphamide · Dexamethasone · Hydrocortisone +6 more
    Synonyms: Malignant lymphoma, no International Classification of Diseases for Oncology subtype
  2. Drug

    Tetryzoline

    go.drugbank.com/drugs/DB06764
    Approved

    [L32599] As it causes profound sedation in children and adults, tetryzoline is increasingly becoming scrutinized for possible drug overdose and toxicity from accidental ingestion. … [A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several cases of drug-facilitated sexual assault.[A231764]

    Mixtures: Visine for Red Eye Cool, Visine for Red Eye WorkplaceCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Pepsin

    go.drugbank.com/drugs/DB13198
    ApprovedWithdrawn

    Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated egg whites to dissolve. … Pepsin is often used as a replacement enzyme for those with pancreatic insufficiency [L2357].

  4. Drug

    Crotonaldehyde

    go.drugbank.com/drugs/DB04381
    Experimental

    Synonyms: trans-but-2-enal
  5. Indication

    Metastatic Colorectal Cancer (CRC)

    go.drugbank.com/conditions/DBCOND0134580
    Drugs: Aflibercept · Bevacizumab · Cetuximab · Encorafenib · Fluorouracil · Fruquintinib +12 more
    Synonyms: Metastasis from malignant neoplasm of colon and/or rectum (disorder)
  6. Target

    Glycogen phosphorylase, liver form

    go.drugbank.com/bio_entities/BE0000007
    TargetHumans

    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis

    Polypeptides: Glycogen phosphorylase, liver form
  7. Drug

    Diazepam

    go.drugbank.com/drugs/DB00829
    ApprovedIllicitInvestigationalVet approved

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the … formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016 [L5200].

  8. Drug

    Bromfenac

    go.drugbank.com/drugs/DB00963
    ApprovedWithdrawn

    Non-ophthalmic formulations of bromfenac were withdrawn in the US in 1998 due to cases of severe liver toxicity.[L43942,T239] … Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation.

    Mixtures: Pred-Brom, Pred-Brom
  9. Target

    Glycogen phosphorylase, muscle form

    go.drugbank.com/bio_entities/BE0000916
    TargetHumans

    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis

    Polypeptides: Glycogen phosphorylase, muscle form
  10. Target

    Glycogen phosphorylase, brain form

    go.drugbank.com/bio_entities/BE0002150
    TargetHumans

    Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228).

    Polypeptides: Glycogen phosphorylase, brain form