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Nomifensine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0127002Drug actionNomifensine, formerly known as Merital capsules, is a dopamine reuptake inhibitor drug that was removed from the market in 1986 for increased incidence of hemolytic anemia. The drug was originally used to treat depression. Nomifensine st...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Gaboxadol
go.drugbank.com/drugs/DB06554InvestigationalGaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing … It acts on the GABA system, but in a seemingly different way from benzodiazepines and other sedatives.
Synonyms: 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-olCategories: Heterocyclic Compounds, 1-RingEtodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedEtodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Synonyms: (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acidMixtures: S-ETODUO 150/300 MG FİLM KAPLI TABLET, 10 ADET, S-ETODUO 150/300 MG FİLM KAPLI TABLET, 14 ADETSNX-5422
go.drugbank.com/drugs/DB06070InvestigationalAs an oral formulation that demonstrates strong efficacy and tolerability, SNX-5422 is positioned as a breakthrough therapy with broad applicability across a wide range of cancers. … SNX-5422 is a synthetic, novel, small molecule Hsp90 Inhibitor.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigationalA branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant Pharmaceuticals and APOTEX have been available since the late 1990s.[L30300] … Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.
International brands: Agapurin SRMixtures: Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5%Propofol
go.drugbank.com/drugs/DB00818ApprovedInvestigationalVet approvedIV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. … Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia.
Synonyms: 2,6-bis(1-methylethyl)phenolMixtures: Anesthesia S/I-60, Anesthesia S/I-40Sennosides
go.drugbank.com/drugs/DB11365ApprovedInvestigationalIt is a weaker laxative than bisacodyl or castor oil[A177092]. … Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and empty the large intestine before surgery.
Salts: Sennosides A and BMixtures: Senna-S, Senexon-SMumps virus strain B level jeryl lynn live antigen
go.drugbank.com/drugs/DB10316ApprovedInvestigationalMumps virus strain B level jeryl lynn live antigen is a live attenuated virus vaccine for subcutenous injection. It is an active immunization against mumps, which is a common childhood disease.
Synonyms: Mumps virus strain B level jeryl lynn live antigenMixtures: PROQUAD® ( Measles, Mumps, Rubella AND Varicella (Oka/Merck) Virus Vaccine Live, MSD) LYOPHILIZED VACCINE;, TRESIVAC 0,5 ML SC ENJEKSIYONLUK ÇÖZELTI IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADETGluconic Acid
go.drugbank.com/drugs/DB13180ApprovedInvestigationalGluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Synonyms: D-Gluconic AcidMixtures: Isolyte S, Isolyte S pH 7.4Sodium phosphate, dibasic
go.drugbank.com/drugs/DB14502ApprovedInvestigationalSynonyms: Phosphoric acid, sodium salt (1:2)Mixtures: ISOLYTE-S PH 7.4 PVC 500 ML(SETLI), ISOLYTE-S PH 7.4 PVC 1000 ML(SETLI)