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Sugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigational[L53333] In combination with platinum-based chemotherapy, sugemalimab is a first-line treatment indicated for adult populations with metastatic non-small cell lung cancer (NSCLC) with no sensitising EGFR … [L32868] Sugemalimab was under investigation in the clinical trial NCT03802591 (A Study of CS1001 in Subjects With Gastric Adenocarcinoma or Gastro-esophageal Junction Adenocarcinoma).
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsBalsam of Peru
go.drugbank.com/drugs/DB11482ApprovedNutraceuticalVet approvedBalsam of Peru is a resin that comes from the tree Myroxylon balsamum pereirae. It is constituted by a mixture of substances from which the major components are benzyl cinnamate and [DB00676]. … [L2879] By Health Canada, the balsam of Peru is approved by the use of over-the-counter combination products and it is currently approved in veterinary products.
Synonyms: bálsamo de PerúMixtures: Arnica De LA Abuela, Stroke II SynergyEplerenone
go.drugbank.com/drugs/DB00700ApprovedInvestigationalEplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative … The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of eplerenone.
Products: INSPRA IC, EPLERENON AL 25MG FTASPARC
go.drugbank.com/bio_entities/BE0002145TargetHumansAppears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites;...
Synonyms: Secreted protein acidic and rich in cysteineCandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalthe blood pressure increasing effects of angiotensin II. … It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract.
Mixtures: CANDESARTAN PL 1A 32/25, CANDESARTAN PL 1A 32/25Categories: Angiotensin II receptor antagonists, Angiotensin II Antagonists and DiureticsEprosartan
go.drugbank.com/drugs/DB00876ApprovedInvestigationalEprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Synonyms: (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acidCategories: Angiotensin II receptor antagonists, Angiotensin II Type 1 Receptor BlockersArginine
go.drugbank.com/drugs/DB00125ApprovedInvestigationalNutraceuticalAn essential amino acid that is physiologically active in the L-form.
Synonyms: L-Arginin, L-(+)-ArginineMixtures: Aminosyn II in Dextrose, Aminosyn II in DextroseSloughing Skin
go.drugbank.com/conditions/DBCOND0111504Drugs: PhentolamineSynonyms: Changes in skin textureTraveler's Diarrhea
go.drugbank.com/conditions/DBCOND0040361Synonyms: Acute Gastroenteritis in Adult TravelersNepidermin
go.drugbank.com/drugs/DB14145InvestigationalInternational brands: Regen-DMixtures: Le-Blen EGF Serum, EASYDEW DW EGF Derma Oneshot Ampoule