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Bendamustine
go.drugbank.com/drugs/DB06769ApprovedInvestigationalBendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). … It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: BENDAMUSTINA DR. REDDY'S, BENDUSTINE 25 MG IV INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADETPyrantel
go.drugbank.com/drugs/DB11156ApprovedVet approvedPyrantel is on the World Health Organization's List of Essential Medicines, which are the safest and most effective medicines required in a functioning health system [L1901], [L1902]. … Pyrantel has shown to be effective after a single dose [L1905]. In humans, it is administered as pyrantel pamoate [A32282],[A32283],[L1893],[L1898].
Mixtures: PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN., PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN.Categories: Heterocyclic Compounds, 1-RingZiprasidone
go.drugbank.com/drugs/DB00246ApprovedInvestigational[A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to treat manic episodes in bipolar disorder although the mechanism of action is unknown. … [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower incidence of metabolic adverse effects compared to other medications in the same class.[A190525]
Categories: Dopamine D2 Receptor Antagonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: ZIPRASIDONE MYLAN GENERICS, ZELDOX IM ENJ. SOL. ICIN KURU TOZ ICEREN FLAKON 20MG/ML FLAKON, 1 ADETAntihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalPEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529]. … PEGylation is the covalent attachment of a polyethylene glycol polymer, called PEG, to a drug or protein.
Categories: Compounds used in a research, industrial, or household settingProducts: ADYNOVATE 500®IU / VIAL, ADYNOVATE®250IU/VIALInsulin pork
go.drugbank.com/drugs/DB00071ApprovedComposed of alpha and beta chains, processed from pro-insulin. Forms a hexameric structure.
Categories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersProducts: Regular Purified Pork Insulin InjRifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawn[L4800] This drug was also sent for review to the EMA in 2015 by Dr. Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801] … The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid.
Mixtures: RİF 250 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ (1 AMPUL), RİF 250 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ (100 AMPUL)Categories: Heterocyclic Compounds with 4 or More Rings, Drugs for Treatment of TuberculosisAstrocytoma
go.drugbank.com/conditions/DBCOND0017186Drugs: CarmustineSynonyms: Astrocytoma, no ICD-O subtype, Astrocytoma, no ICD-O subtype (morphologic abnormality)Bronchospasm
go.drugbank.com/conditions/DBCOND0013567Drugs: Albuterol · Ambroxol acefyllinate · Aminophylline · Atropine · Bambuterol · Bamifylline +12 moreSynonyms: (Bronchospasm) or (O/E - rhonchi (& present)), O/E: [rhonchi present] or [bronchospasm] or [rhonchi]Beclomethasone dipropionate
go.drugbank.com/drugs/DB00394ApprovedInvestigationalBeclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and later in a dry powder inhaler and an aqueous nasal spray. … [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which acts on the glucocorticoid receptor to mediates its therapeutic action.
Synonyms: (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione, 9-chloro-11β-hydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionateInternational brands: Clenil-AMenotropins
go.drugbank.com/drugs/DB00032ApprovedInvestigationalIt is used as a fertility medication that is injected either subcutaneously or intramuscularly. … It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits, alpha = 92 residues, beta=111 residues.
Categories: Sex Hormones and Modulators of the Genital SystemProducts: MENOPUR 600 IU, MENOPUR 1200 IU